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Download Professor Mattias Dobbelstein Listen or ignore – regulatory
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KMEB Seminar Winsløwparken 25 Professor Mattias Dobbelstein Department of Molecular Oncology Faculty of Medicine, University of Göttingen Listen or ignore – regulatory networks determine the cellular response to DNA damage Wednesday 11 March 2009 14:00-15:00 auditorium, Winsløwparken 25 Abstract: DNA damage results in cell death, DNA repair, or malignant transformation. The decision between these outcomes is not just determined by the extent of DNA lesions. Rather, the cells adjust their sensitivity to DNA damage through a signalling network that can be adjusted e. g. through the tumor suppressors p53 and BRCA1. We have identified additional “nods” within this network by a high content cell screening approach. Current research inserts these new players into the existing models of the DNA damage response. Contact: Linda Harkness, [email protected] tlf. (6550) 4082
