Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Slide 1 - AccessMedicine
Document related concepts
Transcript
The central dogma. (A) The central dogma of molecular biology as originally described by Crick. This schematic illustrates the flow of genetic information from DNA to RNA and then to protein, as well as illustrates that DNA serves as its own template in replication. (B) The new central dogma reflects advances in our understanding of molecular processes that occur in normal cells. These processes include epigenetic regulation of gene expression by DNA methylation and histone modification, post-transcriptional regulation of gene expression by microRNAs, and modification of protein functionality by post-translational modification (which might include glycosylation, ubiquitination, phosphorylation, or other). This new central dogma also emphasizes the importance of DNA repair processes in the maintenance of genome integrity. Source: Disease and the Genome: Genetic, Developmental, and Neoplastic Disease, Pathology: A Modern Case Study Citation: Reisner HM. Pathology: A Modern Case Study; 2015 Available at: http://mhmedical.com/ Accessed: August 03, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved
