Download Pedigree Problems 1. The pedigree shows the pattern of inheritance

Pedigree Problems
1. The pedigree shows the pattern of inheritance for a rare human
disease. Filled symbols indicate individuals with the disease; open
symbols indicate normal individuals.
(a) What is the most probable mode of inheritance (dominant or
recessive) for this trait?
(b) What is the most convincing evidence you can give for your
answer to (a)?
(c) What are the most probable genotypes of individuals II-I and II2?
(d) If individuals II-6 and II-7 have another child, what is the
probability that it will be normal? 2. The following pedigree shows the pattern of inheritance for a rare
human disease. Filled symbols indicate individuals with the disease:
open symbols indicate normal individuals.
(a) What is the most probable mode of inheritance (dominant or
recessive) for this trait? On what do you base your answer?
(b) What are the most probable genotypes of individuals I-1 and I2?
(c) What are the most probable genotypes of individuals II-9 and II10?
(d) If individuals II-1 and II-2 have another child, what is the
probability that it will have the disease?
3.
In the following hypothetical pedigree, there are two traits
considered. One gene determines if a person is a vampire or not;
the other gene determines if a person is a werewolf or not. The two
genes sort independently. Study the diagram then answer the
questions below. (HINT: Examine each trait separately when
working out the genotypes.)
(a) Is being a vampire due to a dominant or recessive allele? How
can you tell?
(b) Is being a werewolf due to a dominant or recessive allele? How
can you tell?
(c) Give the most likely genotypes for individuals I-2, II-3, and II-6.
Use D and d for the alleles of the vampire gene and R and r for
the alleles of the werewolf gene.