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Reproductive Systems Homeostasis Body systems maintain homeostasis Homeostasis is essential for survival of cells Cells Cells make up body systems Opening image Slide 1 Vertebral column Ureter Rectum Urinary bladder Seminal vesicle Pubic bone Ejaculatory duct Prostate gland Ductus deferens Anus Penis Bulbourethral gland Urethra Epididymis Cords of erectile tissue Scrotum Glans penis Testis Figure 20.1a Page 751 Slide 2 Urinary bladder Ureter Seminal vesicle Prostate gland Ejaculatory duct Bulbourethral gland Ductus deferens Penis Epididymis Testis Glans penis Urethra Figure 20.1b Page 751 Slide 3 Epididymis Ductus deferens Seminiferous tubules (See next slide) Testis Figure 20.6a Page 759 Slide 4 Lumen of seminiferous tubule Spermatozoon Sertoli cell Spermatids Secondary spermatocyte Primary spermatocyte Tight junction Spermatogonium Figure 20.6d Page 759 Slide 5 Stages Chromosomes in each cell Spermatogonium Spermatogonia Mitotic proliferation Primary spermatocyte First meiotic division Meiosis Secondary spermatocyte Second meiotic division Spermatids Packaging Spermatozoa One daughter cell remains at the outer edge of the seminiferous tubule to maintain the germ cell line One daughter cell moves toward the lumen to produce spermatozoa 46 (diploid number; single strands) 46 (diploid number; single strands) 46 (diploid number; doubled strands) 23 (haploid number; single strands) 23 (haploid number; single strands) 23 (haploid number; doubled strands) Figure 20.7 Page 760 Slide 6 Acrosome Microtubules Mitochondria Nucleus Head Midpiece Tail Figure 20.8b Page 761 Slide 7 Plasma membrane Mitochondria Acrosome Nucleus Centriole Figure 20.8c Page 761 Slide 8 Slide 9 Hypothalamus Gonadotropin-releasing hormone Anterior pituitary FSH-secreting cells LH-secreting cells FSH LH Testes Sertoli cell Leydig cell Spermatogenesis Figure 20.9 Page 762 Inhibin Testosterone Slide 10 Stimulation of mechanoreceptors in glans penis Parasympathetic supply to bulbourethral glands and urethral glands Parasympathetic supply to penile arterioles Sympathetic supply to penile arterioles Mucus Penile arterioles dilate Lubrication Erection Compresses veins Figure 20.11 Page 767 Slide 11 Oviduct Ovary Vertebral column Fimbriae Uterus Cervix Urinary bladder Rectum Pubic bone Vagina Urethra Clitoris Labium minora Anus Labium majora Figure 20.2a Page 752 Slide 12 Ovarian vessels Oviduct Endometrium Ovary Fimbriae Myometrium Uterus Cervical canal Cervix Vagina Figure 20.2b Page 752 Slide 13 Clitoris Opening of urethra Labium minora Hymen Vaginal opening Labium majora Perineum Anus Figure 20.2c Page 752 Slide 14 Stages Chromosomes in each cell Oogonium Mitotic proliferation prior to birth 46 (diploid number; single strands) (Arrested in first meiotic division) Primary oocytes After puberty, one primary oocyte reaches maturity and is ovulated about once a month until menopause ensues Enlarged primary oocyte (First meiotic division completed just prior to ovulation) Meiosis 46 (diploid number; doubled strands) 46 (diploid number; doubled strands) 23 (diploid number; doubled strands) Secondary oocyte First polar body Second polar body Polar bodies degenerate 23 (haploid number; single strands) from (Second meiotic ovum plus division 23 (haploid number; completed single strands) from after fertilization) sperm for diploid Mature fertilized ovum with ovum 46 chromosomes Figure 20.12 Page 771 Slide 15 Primary follicles (40 mm) Primary oocyte Single layer of granulosa cells Fig. 20.13a (1) Page 773 Slide 16 Follicular cells Proliferation of granulosa cells Zona pellucida Differentiation of surrounding ovarian connective tissue into thecal cells Primary oocyte Developing secondary follicle Fig. 20.13a (2) Page 773 Slide 17 Beginning of formation of antrum Developing secondary follicle Fig. 20.13a (3) Page 773 Slide 18 Thecal cells Granulosa cells Antrum Zona pellucida Ovum (primary oocyte) Developing secondary follicle Fig. 20.13a (4) Page 773 Slide 19 Ovarian surface Antrum Ovum (secondary oocyte) Mature follicle (12-16 mm) Fig. 20.13a (5) Page 773 Slide 20 Ovulated ovum (secondary oocyte) Follicular remnant Corona radiata Zona pellucida Figure 20.13b Page 773 Slide 21 Developing corpus luteum Fig. 20.13c (1) Page 773 Slide 22 Corpus luteum Fig. 20.13c (2) Page 773 Slide 23 Degenerating corpus luteum Figure 20.13d Page 773 Slide 24 Secondary follicle Mature follicle Primary follicle Corpus luteum Figure 20.13e Page 773 Slide 25 Plasma concentrations of gonadotropic hormones LH FSH Fig. 20.15 (1) Page 775 Slide 26 Plasma concentrations of gonadal hormones Estrogen Progesterone Fig. 20.15 (2) Page 775 Slide 27 Ovary Follicular development Ovulation Development of corpus luteum Degeneration of corpus luteum Fig. 20.15 (3) Page 775 Slide 28 Uterus (endometrial thickness) Fig. 20.15 (4) Page 775 Slide 29 Uterine phases Ovarian phases Menstrual phase Proliferative phase Follicular phase Ovulation Secretory, or progestational, phase Luteal phase New menstrual phase New follicular phase Fig. 20.15 (5) Page 775 Slide 30 LH FSH Thecal cells Granulosa cells Cholesterol (converted to) (Diffuses from thecal cells into granulosa cells) Androgen Androgen (converted to) Estrogen Secreted into blood Remains in the follicle Exerts effects throughout body Contributes to antral formation Figure 20.16 Page 776 Slide 31 Hypothalamus Gonadotropin-releasing hormone (GnRH) Anterior pituitary FSH-secreting cells LH-secreting cells LH FSH Ovary Follicular development Low levels of estrogen Inhibin Figure 20.17 Page 777 Slide 32 Hypothalamus GnRH Anterior pituitary LH-secreting cells FSH-secreting cells FSH LH Ovary Mature follicle (LH surge) Inhibin Ovulation High levels of estrogen Figure 20.18 Page 778 Slide 33 Hypothalamus GnRH Anterior pituitary LH Ovary Corpus luteum Moderate levels of estrogen High levels of progesterone Figure 20.19 Page 779 Slide 34 Location Time of appearance Percent of (min after ejaculated ejaculation) sperm* Fertilization site (upper third of oviduct) 30–60 Uterus 10–20 Cervical canal Vagina Oviduct Optimal site of fertilization Ampulla of oviduct 0.001 Sperm surrounding ovum 0.1 Ovary Uterus 1–3 3 0 100 Ovulated ovum Fimbria Cervical canal *Based on data from animals. Sperm and ovum enlarged. Vagina 180 million sperm deposited Penis Figure 20.20 Page 782 Slide 35 Nucleus of ovum undergoing second meiotic division Corona radiata Cytoplasm of ovum First polar body Zona pellucida Spermatozoa Plasma membrane of ovum (See next slide) Fig. 20.22a (1) Page 783 Slide 36 Enzyme-filled acrosome Spermatozoon head bearing sperm’s nucleus Path tunneled through barriers surrounding ovum by acrosomal enzymes exposed on disruption of acrosomal membrane Spermatozoon that has accomplished fertilization Fig. 20.22a (2) Page 783 Slide 37 Blastocoele Blastocyst (cross section) Becomes amniotic sac Spermatozoa Morula Ovum (cross section) Cleavage Inner cell mass Destined to become fetus Fertilization Trophoblast Accomplishes implantation and develops into fetal portions of placenta Secondary oocyte (ovum) Ovulation Ovary Implantation Endometrium of uterus Fig. 20.23 Page 784 Slide 38 Endometrium Uterine cavity Inner cell mass Capillary Cords of trophoblastic cells Blastocoel Trophoblast (surface layer of cells of the blastocyst) Surface of uterine lining Fig. 20.25 (1) Page 785 Slide 39 Surface of uterine lining Decidua Cords of trophoblastic cells Inner cell mass Fig. 20.25 (2) Page 785 Slide 40 Surface of uterine lining Decidua Developing embryo Fig. 20.25 (3) Page 785 Slide 41 8 weeks (See next slide) Fig. 20.26a (1) Page 787 Slide 42 12 weeks Full term Fig. 20.26a (2) Page 787 Slide 43 Umbilical cord Amniotic sac Pool of maternal blood Placental villus Intervillus space Uterine decidual tissue Maternal arteriole Maternal venule Fetal vessels Chorion Chorionic tissue Placenta Umbilical vein Umbilical artery Figure 20.26b Page 787 Slide 44 Human chorionic gonadotropin (hCG) Estrogen Progesterone Fertilization Delivery Figure 20.27 Page 791 Slide 45 Maternal blood Placenta Fetal blood Fetal adrenal cortex Pathway for placental synthesis of progesterone Pathway for placental synthesis of estrogen Figure 20.28 Page 791 Slide 46 Placenta CRH (into fetal circulation) Fetal anterior pituitary The blue arrows designate the sequence of events leading to the onset of parturition. ACTH Fetal adrenal cortex The green arrows designate the positive-feedback cycle responsible for the progression of parturition. Cortisol DHEA Fetal lungs Placenta Pulmonary surfactant Conversion of DHEA to estrogen Lung maturation in readiness for breathing air Estrogen Gap junctions between myometrial cells Uterus able to contract as a coordinated unit Oxytocin receptors in myometrium Uterine responsiveness to low levels of oxytocin Triggers onset of parturition Prostaglandin production Cervical softening Fig. 20.29 (1) Page 793 Slide 47 The blue arrows designate the sequence of events leading to the onset of parturition. The green arrows designate the positive-feedback cycle responsible for the progression of parturition. Uterine contractions Push fetus against cervix Responsible for progression of parturition (through neuroendocrine reflex) Oxytocin secretion Prostaglandin production Fig. 20.29 (2) Page 793 Slide 48 Placenta Urinary bladder Pubic bone Urethra Vagina Cervix Rectum Figure 20.30a Page 795 Slide 49 Placenta Umbilical cord Partially dilated cervix First stage of labor: Cervical dilation Uterus Second stage of labor: Delivery of the baby Third stage of labor: Delivery of the placenta Figure 20.30b Page 795 Slide 50 Adipose tissue Duct Nipple Lobule containing alveoli Figure 20.31a Page 796 Slide 51 Myoepithelial cell Duct Ejection Secretion Milk (Lumen) Alveolar epithelial cell Figure 20.31b Page 796 Slide 52 Suckling Mechanoreceptors in nipple Hypothalamus Nervous pathway Prolactin-inhibiting hormone or prolactin-releasing hormone (?) Posterior pituitary Anterior pituitary Oxytocin Prolactin Contraction of myoepithelial cells surrounding alveoli Milk secretion Milk ejection Figure 20.32 Page 797 Slide 53