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Transcript
PowerPoint® Lecture Slides
Prepared by Patty Bostwick-Taylor,
Florence-Darlington Technical College
CHAPTER
7
The Nervous
System
© 2012 Pearson Education, Inc.
B. Peripheral Nervous System (PNS)
•Nerves and ganglia outside the central
nervous system
•Nerve = bundle of neuron fibers
•Neuron fibers are bundled by connective
tissue
© 2012 Pearson Education, Inc.
PNS: Structure of a Nerve
•Endoneurium surrounds each fiber
•Groups of fibers are bound into fascicles by
perineurium
•Fascicles are bound together by epineurium
© 2012 Pearson Education, Inc.
Axon
Myelin sheath
Endoneurium
Perineurium
Epineurium
Fascicle
Blood
vessels
© 2012 Pearson Education, Inc.
Figure 7.23
PNS: Classification of Nerves
•Mixed nerves
•Both sensory and motor fibers
•Sensory (afferent) nerves
•Carry impulses toward the CNS
•Motor (efferent) nerves
•Carry impulses away from the CNS
© 2012 Pearson Education, Inc.
Spinal Cord
•Extends from the foramen magnum of the
skull to the first or second lumbar vertebra
•Provides a two-way conduction pathway from
the brain to and from the brain
•31 pairs of spinal nerves arise from the spinal
cord
•Cauda equina is a collection of spinal nerves
at the inferior end
© 2012 Pearson Education, Inc.
Cervical
spinal nerves
Cervical
enlargement
C8
Dura and
arachnoid
mater
© 2012 Pearson Education, Inc.
Thoracic
spinal nerves
Figure 7.20 (1 of 2)
Lumbar
enlargement
T12
Cauda
equina
End of
meningeal
coverings
End of
spinal cord
Lumbar
spinal nerves
L5
S1
Sacral
spinal nerves
S5
© 2012 Pearson Education, Inc.
Figure 7.20 (2 of 2)
Spinal Cord Anatomy
• Internal gray matter is mostly cell bodies
• Dorsal (posterior) horns
• Anterior (ventral) horns
• Gray matter surrounds the central canal
• Central canal is filled with cerebrospinal fluid
• Exterior white mater — conduction tracts
• Dorsal, lateral, ventral columns
© 2012 Pearson Education, Inc.
Dorsal root
ganglion
White matter
Central canal
Dorsal (posterior)
horn of gray matter
Lateral horn of
gray matter
Spinal nerve
Dorsal root of
spinal nerve
Ventral root
of spinal nerve
Ventral (anterior)
horn of gray matter
Pia mater
Arachnoid mater
Dura mater
© 2012 Pearson Education, Inc.
Figure 7.21
Spinal Cord Anatomy
• Meninges cover the spinal cord
• Spinal nerves leave at the level of each vertebrae
• Dorsal root
• Associated with the dorsal root ganglia—
collections of cell bodies outside the central
nervous system
• Ventral root
• Contains axons
© 2012 Pearson Education, Inc.
Interneuron carrying sensory
information to cerebral cortex
Integration (processing
and interpretation of
sensory input) occurs
Cerebral cortex
(gray matter)
White matter
Interneuron carrying
response to
motor neurons
Thalamus
Cerebrum
Interneuron
carrying response
to motor neuron
Brain stem
Cell body of sensory
neuron in sensory
ganglion
Interneuron carrying
sensory information to
cerebral cortex
Nerve
Skin
Sensory
receptors
Cervical spinal cord
Muscle
© 2012 Pearson Education, Inc.
Motor output
Motor neuron
cell body
White matter
Gray matter
Interneuron
Figure 7.22
PNS: Spinal Nerves
•There is a pair of spinal nerves at the level of
each vertebrae for a total of 31 pairs
•Formed by the combination of the ventral and
dorsal roots of the spinal cord
•Named for the region from which they arise
© 2012 Pearson Education, Inc.
Cervical
nerves
Thoracic
nerves
Lumbar
nerves
Sacral
nerves
C1
2
3
4
5
6
7
8
T1
2
3
4
5
6
7
8
9
10
11
Ventral rami form
cervical plexus
(C1 – C5)
Ventral rami form
brachial plexus
(C5 – C8; T1)
No plexus
formed
(intercostal
nerves)
(T1 – T12)
12
L1
2
3
4
Ventral rami form
lumbar plexus
(L1 – L4)
5
(a)
© 2012 Pearson Education, Inc.
S1
2
3
4
Ventral rami form
sacral plexus
(L4 – L5; S1 – S4)
Figure 7.25a
PNS: Anatomy of Spinal Nerves
•Spinal nerves divide soon after leaving the
spinal cord
•Ramus — branch of a spinal nerve; contains
both motor and sensory fibers
•Dorsal rami — serve the skin and muscles
of the posterior trunk
•Ventral rami — form a complex of networks
(plexus) for the anterior
© 2012 Pearson Education, Inc.
Dorsal root
Dorsal root
ganglion
Spinal
cord
Ventral
root
Spinal nerve
(b)
© 2012 Pearson Education, Inc.
Dorsal
ramus
Ventral
ramus
Figure 7.25b
PNS: Spinal Nerve Plexuses
• Plexus – networks of nerves serving motor and
sensory needs of the limbs
• Form from ventral rami of spinal nerves in the
cervical, lumbar, and sacral regions
• Four plexuses:
• Cervical
• Brachial
• Lumbar
• Sacral
© 2012 Pearson Education, Inc.
PNS: Spinal Nerve Plexuses
•Cervical Plexus
•Originates from ventral rami in C1 – C5
•Important nerve is the phrenic nerve
•Areas served:
• diaphragm, shoulder and neck
© 2012 Pearson Education, Inc.
PNS: Spinal Nerve Plexuses
•Brachial Plexus
•Originates from ventral rami in C5 – C8 and T1
•Important nerves:
• Axillary
• Radial
• Median
• Musculocutaneous
• Ulnar
• Areas served: shoulder, arm, forearm, and hand
© 2012 Pearson Education, Inc.
Axillary nerve
Humerus
Radial
nerve
Musculocutaneous
nerve
Ulna
Radius
Ulnar nerve
Radial nerve
(superficial
branch)
Median nerve
(a) The major nerves
of the upper limb
© 2012 Pearson Education, Inc.
Figure 7.26a
PNS: Spinal Nerve Plexuses
•Lumbar Plexus
•Originates from ventral rami in L1 through L4
•Important nerves:
•Femoral
•Obturator
•Areas served:
• lower abdomen, anterior and medial thighs
© 2012 Pearson Education, Inc.
Femoral
Lateral
femoral
cutaneous
Obturator
Anterior
femoral
cutaneous
Saphenous
© 2012 Pearson Education, Inc.
(b) Lumbar plexus,
anterior view
Figure 7.26b
PNS: Spinal Nerve Plexuses
•Sacral Plexus
•Originates from ventral rami in L4 – L5 and
S1 – S4
•Important nerves:
• Sciatic
• Superior and inferior gluteal
•Areas served:
• Lower trunk and posterior thigh
• Lateral and posterior leg and foot
• Gluteal muscles of hip area
© 2012 Pearson Education, Inc.
Superior
gluteal
Inferior
gluteal
Sciatic
Posterior
femoral
cutaneous
Common
fibular
Tibial
Sural (cut)
Deep
fibular
Superficial
fibular
Plantar
branches
© 2012 Pearson Education, Inc.
(c) Sacral plexus, posterior view
Figure 7.26c
© 2012 Pearson Education, Inc.
Figure 7.2
PNS: Differences Between Somatic
and Autonomic Nervous Systems
Somatic Nervous
System
Autonomic Nervous
System
Nerves
One-neuron; it
originates in the CNS
and axons extend to
the skeletal muscles
served
Two-neuron system
consisting of
preganglionic and
postganglionic
neurons
Effector organ
Skeletal muscle
Smooth muscle,
cardiac muscle,
glands
Subdivisions
None
Sympathetic and
parasympathetic
Neurotransmitter
Acetylcholine
Acetylcholine,
epinephrine,
norepinephrine
© 2012 Pearson Education, Inc.
PNS: Somatic Nervous System
•Motor subdivision of PNS
•Affects skeletal muscles
•Also known as voluntary nervous system
© 2012 Pearson Education, Inc.
PNS: Autonomic Nervous System
• Motor subdivision of the PNS
• Consists only of motor nerves
• Also known as the involuntary nervous system
• Regulates activities of cardiac and smooth
muscles and glands
• Two subdivisions
• Sympathetic division
• Parasympathetic division
© 2012 Pearson Education, Inc.
Central
nervous system
Peripheral nervous system
Effector organs
Acetylcholine
Skeletal
muscle
Somatic nervous system
Acetylcholine
Autonomic
nervous
system
Sympathetic
division
Smooth muscle
(e.g., in stomach)
Norepinephrine
Ganglion
Acetylcholine
Epinephrine and
norepinephrine
Adrenal medulla
Acetylcholine
Blood
vessel
Glands
Cardiac
muscle
Parasympathetic
division
Ganglion
KEY:
Preganglionic
axons
(sympathetic)
© 2012 Pearson Education, Inc.
Postganglionic
axons
(sympathetic)
Myelination
Preganglionic
axons
(parasympathetic)
Postganglionic
axons
(parasympathetic)
Figure 7.27
(a) Parasympathetic Division
• Preganglionic neurons originate from the craniosacral
regions:
• The cranial nerves III, VII, IX, and X
• S2 through S4 regions of the spinal cord
• Due to site of preganglionic neuron origination, the
parasympathetic division is also known as the
craniosacral division
• Terminal ganglia are at the effector organs
• Neurotransmitter: acetylcholine
© 2012 Pearson Education, Inc.
(b) Sympathetic Division
• Preganglionic neurons originate from T1 through L2
• Ganglia are at the sympathetic trunk (near the spinal cord)
• Short pre-ganglionic neuron and long post-ganglionic
neuron transmit impulse from CNS to the effector
• Neurotransmitters: norepinephrine and epinephrine
(effector organs)
© 2012 Pearson Education, Inc.
Parasympathetic
Sympathetic
Eye
Eye
Brain stem
Salivary
glands
Heart
Skin
Cranial
nerves
Sympathetic
ganglia
Salivary
glands
Cervical
Lungs
Lungs
T1
Heart
Stomach
Thoracic
Stomach
Pancreas
Pancreas
L1
Liver and
gallbladder
Lumbar
Pelvic
splanchnic
nerves
© 2012 Pearson Education, Inc.
Adrenal
gland
Bladder
Bladder
Genitals
Liver
and gallbladder
Genitals
Sacral nerves (S2 – S4)
Figure 7.28
Lateral horn of
gray matter
Dorsal ramus
of spinal nerve
Dorsal root
Sympathetic
trunk
Spinal
nerve
(a)
(b)
(c)
Ventral root
Sympathetic
trunk ganglion
Splanchnic
nerve
Ventral ramus
of spinal nerve
To effector:
blood vessels,
arrector pili
muscles, and
sweat glands
of the skin
Gray ramus
communicans
White ramus
communicans
Collateral ganglion
(such as the celiac)
Visceral effector organ
(such as small intestine)
© 2012 Pearson Education, Inc.
Figure 7.29
Sympathetic Functioning
•Sympathetic — “fight or flight”
•Response to unusual stimulus
•Takes over to increase activities
•Remember as the “E” division
•exercise, excitement, emergency, and
embarrassment
© 2012 Pearson Education, Inc.
Parasympathetic Functioning
• Parasympathetic — “housekeeping” activites
•Conserves energy
•Maintains daily necessary body functions
•Remember as the “D” division
•digestion, defecation, and diuresis
© 2012 Pearson Education, Inc.
Homeostatic Imbalance
• Cerebral Palsy
• Neuromuscular
• Voluntary muscles are poorly controlled and spastic
• Anencephaly
• Failure of the cerebrum to develop
• Cannot hear, see, or process sensory inputs
• Spina Bifida
• Incomplete formation of vertebrae
• Meninges, nerve roots, and spinal cord can be
damaged
© 2012 Pearson Education, Inc.
Development Aspects of the Nervous
System
•No more neurons are formed after birth, but
growth and maturation continues for several
years
•The brain reaches maximum weight as a
young adult
© 2012 Pearson Education, Inc.