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Evaluation of the risk factors of chronic respiratory diseases
in Ho Chi Minh City, Vietnam: preliminary results
Ha Chu Thi, Nguyen Huu Lan, Nguyen Huy Dung, Nguyen Hong Duc(1), Isabelle Godin (2), Olivier Michel (3).
(1) Pham Ngoc Thach Hospital (PNT-H), (2) Ecole de Santé Publique et (3) CHU Brugmann, UniversitéLibre de Bruxelles
(ULB)Bruxelles, Bruxelles, Belgique
Background: the chronic respiratory diseases (CRD) include the Chronic Obstructive Pulmonary
Diseases (COPD), asthma and restrictive defects. The main causes of CRD are tobacco smoke,
occupational factors, indoor and outdoor air pollution, allergens and sequellae of tuberculosis.
Aim: to evaluate the relative prevalence of the different CRD and their risk factors, among the
population of Ho Chi Minh City (HCMC).
Methods: Design: a cross-sectional-observational study. Inclusion: patients with symptoms
suggestive CRD: cough, sputum, chest tightness, wheezing, dyspnea.
End points: Lung function tests (LFT), allergic skin prick tests (SPT) and the questionnaire
Classical COPD (or suspected
COPD): FEV1/FVC < 0.70 (or
< 0.75), with no significant
response after SB.
Asthmatics:
FEV1/FVC < 0.75 and
increased significantly after
inhalation of salbutamol (SB).
Other CRD:
FEV1/FVC > 0.75 with
restrictive (low
FEV1and FVC).
Results: the results are preliminary, based on 122 evaluable patients (median age 52 years).
General characteristics of population
84%
Home characteristics
94%
80%81%77%
Series1
Series1
88%
69%
53%
52%
41%
38% 37%
25%
23%
19%
COPD: 74 %
• 34 non-smokers
• 20 patients: no history of TB
and/or occupational risk factors
29%
Asthmatics: 21 %
• 9 atopic
• 17 non-atopic
Other CRD: 5 %
82%
51%
35%37%
Compared COPD and asthma:
jobless (p< 0.05)
Known diagnosis of COPD: 4%
Known diagnosis of asthma: 32%
Conclusions:
1/ COPD was the most frequent CRD in HCMC;
2/ While cumulative smoking was frequent, more than 1/3 COPD were non smokers, suggesting
others environmental risk factors (such as incense use);
3/ Sensitization to allergen is infrequent in asthma, suggesting they were sensitized to unknown
domestic or occupational allergens;
4/ Among the general population, less than 10% of CRD had a specific diagnosis, and therefore
could be treated inadequately.