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TEXAS STATE UNIVERSITY HEALTH SCHOLAR SHOWCASE Prepared by Dr. Casey Smith-Physics Department, Cleanroom Director Facilities and Resources Common Instrumentation and Facilities Chromatograph: used to separate the components of a gas or liquid mixture based on size, mobility, and/or charge Electron Microscopy Equipment Example Research Thrusts Supported by this Equipment Advanced Drug Synthesis and Collaborative in-vivo/vitro Studies Targeting Lung Cancer FEI Helios SEM 0.9nm resolution, dual beam configuration, EDS PI – Sean Kerwin, Associate Professor, Chemistry and Biochemistry; [email protected] Functional Nanomaterial Synthesis for Site Specific Therapies Targeting Cancer PI – Tania Betancourt, Assistant Professor, Chemistry and Biochemistry, MSEC; [email protected] High Speed Centrifuge: used to separate nanoscale components of a liquid mixture via sedimentation Investigation of Fundamental Principles Governing Binding Between Proteins and RNA Molecules PI – Karen Lewis, Assistant Professor, Chemistry and Biochemistry; [email protected] Freeze Dryer: used to preserve samples by removing solvent via sublimation under reduced pressure Mass Spectrometer: used to quantify the mass to charge ratio in ionized samples, there are many methods of ionizing and charge detection JEOL 1200 TEM 120kV column, Gatan CCD Biosafety Cabinet: used to protect researchers and from and preserve purity of pathogenic samples Microfluidic Lab-on-a-Chip for Rapid Pathogen Detection and Diagnosis PI – Shannon Weigum, Assistant Professor, Biology, MSEC; [email protected] Fundamental Investigation of Intrinsically Disordered Proteins PI – Steve Whitten, Associate Professor, Chemistry and Biochemistry; [email protected] Deployment Across Campus Chemistry & Biochemistry Department – P.I. Labs Biology Department – P.I. Labs Spectrophotometers: used to quantify sample transmission, reflectance, and/or emission from sample(s) as a function of wavelength (UV-nIR). Several models also control temperature and pH. Live Cell Imaging: used to noninvasively monitor in vitro metabolic processes Specialized Equipment LED Epifluorescence microscope: used to generate high resolution maps and automated counting of cell populations . Laser Engraver: used to create low-cost microfluidic panels for detection and diagnosis of pathogens JEOL JSM-6010 SEM Low and high vacuum modes, incredible ease of use Confocal microscope: used to capture laser excited samples and generate 3D maps of fixed and living cells Materials Science Engineering and Commercialization Program - Analysis Research Services Center (ARSC) For more information regarding access to these resources, please contact: Casey Smith; [email protected]; RFM 1244; 512-245-6635