Download 2015 department of medicine research day

2015 DEPARTMENT OF MEDICINE RESEARCH DAY
Title of Poster: A Population-Based Analysis of Oral Cavity Cancer in 55,775 Patients
Presenter: Jose Alonso, MSIII
Division: Head & Neck Surgery
☐Faculty ☐Fellow ☐Resident ☐Post-doc Research Fellow ☐Graduate Student ☒Medical Student ☐Other
Principal Investigator/Mentor: Maie St. John MD
Co-Investigators: John W. Frederick MD
Thematic Poster Category: Clinical Observations and Clinical Trials
Outcomes and Objectives: The goals of this review were to characterize trends in the treatment of
oral cavity cancer over time and to compare outcomes across large patient populations.
Methods: The population-based Surveillance, Epidemiology, and End Results (SEER) cancer registry
was utilized to identify all patients between 1972-2011 diagnosed with oral cavity malignancy. A
retrospective cohort analysis of this group was compiled and specific demographic data, treatment
modalities, and survival outcomes were recorded. Differences in outcomes based on treatment
modality, year of diagnosis, and demographic factors were evaluated using Kaplan-Meier methods and
multivariate analysis.
Results: We identified a total of 55,775 patients diagnosed with oral cavity malignancy. The
majority of patients (59%) were male and most patients fell between the ages of 41-79 (80%).
Treatment groups included surgery, radiation, or a combination of surgery and radiation. The most
common treatment modality was surgery alone (53%), while 26% of patients received a combination
of surgery and radiation or were treated with radiation (20%). There was a significant difference in
treatment modality used depending on patient race. Trends in modality used overtime were
consistent. Improved survival was seen in patients receiving surgery alone and depended on race and
year of diagnosis.
Conclusion: Patient factors are associated with the treatment and survival of oral cavity cancer and
these factors should be considered in the treatment of the disease.