Download Introduction to Basic Therapeutics Module

Introduction to Basic
Therapeutics Module
Dr. Naser Ashraf Tadvi
Module coordinator
Objectives
• Describe the concept of Module, including
objectives, learning contents, teaching and
learning methodology, practicals, references,
assessment, and all module related matter
• Understand computer assisted learning in
experimental Pharmacology
• Briefly overview the concept of pharmacology
Concept of the Module
Theme I: Different Therapeutic Modalities
• Introduction to different therapeutic
modalities.
• Non-pharmacological basis of therapy (e.g.
physiotherapy, occupational therapy,
radiotherapy, counseling & CAM)
• Introduction to pharmacotherapeutics
Theme II:
How body handles drugs (Pharmacokinetics):
 Absorption.
 Distribution.
 Metabolism.
 Elimination.
How drug acts (Pharmacodynamics):
 Receptors (affinity, efficacy & potency).
 Theory of drug receptors binding.
 Signal transduction apparatus.
 Therapeutic index and therapeutic window
Individual variations in drug response (pharmacogenomics)
 Introduction to Pharmacogenomics.
 Clinical relevance of Pharmacogenomics
Theme III: Autonomic Pharmacology
& Autocoids
Autonomic nervous system drugs
• Adrenergic agonists & antagonists.
• Cholinergic agonists & antagonists.
• Skeletal muscles relaxants.
Autacoids (histamine, serotonin & prostaglandins)
• Histamine and antihistamines
• Serotonin and anti–serotonin
• Prostaglandins and ergot alkaloids
Theme IV: Rational & safe prescription
including drug development
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Drug therapy during pregnancy & lactation
Drug therapy in the geriatric & pediatric groups.
Adverse drug reaction (ADR).
Principles of toxicology.
Drug interactions
Safe prescribing habits.
Cost effective drug therapy.
Compliance & adherence
Monitoring of drug treatment
National & international drug evaluation & regulation
Teaching and learning methods
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Lectures: 30
PBL: 4
CD: 5
Seminars: 5
Practicals: 6
Tutorial: 2
Field Visit: 1
Practicals
• All practicals have Computer Assisted Learning
• At the end of each practical the students will be
evaluated in the last half hour
• The quiz for each practical will be of ten marks
• MCQs or SEQs related to practical can be asked
• There will be no separate mid term practical
exam
• 10 % of these marks will be considered as
midterm practical exam marks
Assessment
• Continuous Assessment
• Final Assessment
60%
40%
Continuous assessment
Mid Module exam
Multiple choice questions
Short essay questions
Activities Marks
Problem Based Learning
(PBLs)
Case Discussion (CDs)
Quiz PBL, CDs, Seminars
Seminar
Mid Term Practical Exam
60 marks
40 Marks
20 %
40 MCQs
05 SEQs
30 %
160 Marks
04 PBLs
75 Marks
05 CDs
40 Marks
100 Marks
Practical 2,3,4
30 Marks
04 Quiz
01 Seminar
10% of this
Mid module exam (will cover)
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Lecture 1 to lecture 15
PBL 1 & PBL 2
CD 1 & CD 2
Seminar 1 & Seminar 2
Quizzes (10 marks each)
• Quiz 1
– PBL 1, CD1, Seminar 1
• Quiz 2
– PBL 2, CD2, Seminar 2
• Quiz 3
– PBL 3, Seminar 3, CD 3
• Quiz 4
– PBL 4, Seminar 4, seminar 5, CD4, CD5
Final Assessment
Final Assessment
Final module examination
Multiple choice questions
Short essay questions
Final Practical examination
60 marks
40 Marks
40 %
30 %
60 MCQs
05 SEQs
10 %
Attendance
• 75 % attendance is compulsory for eligibility in
exam
• PBLs, CDs, quizzes, practical's and Seminars
absence will lead to loss of marks in
continuous assessment
Concept of Pharmacology
• Drug therapy involves a great deal more than
matching the name of the drug to the name of
a disease; it requires knowledge, judgement,
skill and wisdom, but above all a sense of
responsibility.
Learning resources
• Illustrated reviews Pharmacology, Ed.
Lippincott. 5th Edition,
• Katzung & Trevor’s Basic and Clinical
Pharmacology. 12th Edition,
• Reference book:
– Goodman & Gilman Pharmacological Basis of
Therapeutic 2011- 12th Edition
At the end of module