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CHE 102 - Homework - Ch 30a Enzymes Name: Date: 1. Define Activation Energy and discuss how it controls the rate of a reaction. Draw a reaction/energy diagram illustrating how a catalyst speeds up a reaction. Be sure to label the: (R)eactants, (P)roducts, (T)ransition state, Activation Energy (AE) and the Catalyzed Activation Energy (CAE). Is the reaction you drew endothermic or exothermic? Explain 2. What is a Holoenzyme? 3. Chose the set of conditions that would yield a faster enzyme-catalyzed reaction. Explain your answer. (A) [reactant] = 0.013 M, Temp = 68℃, and an activation energy of 38 kcal/mol vs (B) [reactant] = 0.013 M, Temp = 55℃, and an activation energy of 38 kcal/mol Explain. CHE 102 - Homework - Ch 30a Enzymes 4. What is an enzyme active site? (Use your own words and complete sentences) 5. What is the ”lock-and-key” hypothesis? Why is it a good model? Why is it a bad model? (Use complete sentences) 6. What does the term ”stereospecific” mean. (Use complete sentences) 7. List 3 ways that a substrate binding to an active site helps the reactants be converted to products. Explain. (Use complete sentences) CHE 102 - Homework - Ch 30a Enzymes 8. Define ”Feedback Inhibition” and ”Feedforward Activation”. (Use complete sentences) 9. The amino acid glutamine is produced by a metabolic pathway in the liver. As the concentration of glutamine increases the metabolic pathway slows down. Is this control feedforward activation or feedback inhibition? Explain. 10. Draw a graph illustrating the effect of temperature on the rate of enzyme-catalyzed reactions. Explain why the enzyme-catalyzed reaction rate decreases at lower temperatures? Label the value on the x-axis that corresponds to the peak in your graph. (Use complete sentences) 11. What is the difference between Maltose and Maltase? 12. Ubertase catalyzes the reaction that converts ethanol to ethanal. What class of enzymes does Ubertase belong to? Explain.