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Division of Cardiothoracic Surgery
Thoracic Surgery Residency Program
Introduction
Welcome to the Thoracic Surgery Residency
Program at the University of Colorado.
Our
program is a three-year residency which has been in continuous operation since
1977. Our mission is to provide a very well-rounded thoracic surgical education
in all facets of our specialty. Our global objective is to prepare the graduates of
our program to step into their careers prepared to meet the challenges of the
profession, regardless of their ultimate career goals.
During the course of the three-year curriculum, residents rotate through the
University of Colorado Hospital, Children’s Hospital Colorado, and the
Department of Veterans Affairs Medical Center, Denver. These rotations
provide a robust and sophisticated experience in all facets of adult and
congenital heart disease and general thoracic surgery. The first two years of the
three-year curriculum are designed to provide an in-depth experience in each of
these subspecialty areas and prepare the resident for eligibility for the American
Board of Thoracic Surgery examination process. The third year of the residency
is designed in a manner to permit the resident to focus in an area relevant to
their ultimate career goals. For example, some of our residents focus their
activities in the arena of general thoracic surgery, and others in the arena of
congenital heart surgery. Regardless of a resident’s career goal, the faculty is
absolutely committed to helping all residents achieve their goals.
The graduates of our program have established very successful careers across
the country. Our graduates are established cardiac and thoracic surgeons in
both academic medical centers and private practice.
Regardless of the particular area of clinical focus, the graduates of our programs
have consistently provided feedback that they were more than ready to function
independently upon completion of the residency program.
Thank you for your interest in our program.
Sincerely,
David A. Fullerton, MD
Professor and John T.M. Wright Endowed Chair in Heart Valve Surgery
Chief, Division of Cardiothoracic Surgery
Residency Program Director
University of Colorado School of Medicine
Karen H. Muth, BA
Thoracic Surgery Residency Program Coordinator
University of Colorado School of Medicine
Residency Program
Educational Goals and Objectives
The global objective of the thoracic surgery residency program is to teach
residents the skills necessary to become well-rounded cardiothoracic
surgeons. In addition, it is our interest to align our training program with
modern career objectives. The rotation schedule for the residency is designed
to achieve this global objective, while at the same time permitting enough
flexibility within the program to accommodate the desire of the resident to
focus on a particular subspecialty, such as general thoracic or adult cardiac
surgery. Throughout the residency, the resident is given graded responsibility
both in and outside the operating room.
Year 1 - Adult Cardiac Surgery
During the first year a resident’s time will
be divided between the adult cardiac
service and the general thoracic service.
The goals and objectives during the first
year are:
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Medical management and indications for surgery of ischemic and valvular
heart disease
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Preoperative evaluation of patients
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Risks of the operations and how to counsel patients appropriately
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Perioperative management of patients following complicated cardiac and
general thoracic procedures
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ICU care, including ventilator management, nutritional support, inotropic
management, and management of intra-aortic balloon pumps
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Acquire graded responsibilities as primary surgeon to perform operations
for coronary revascularization, valve repair and replacement, and aortic
disease

Acquire graded responsibilities as primary surgeon for heart and lung
procurements for transplantation
Year 1 - General Thoracic Surgery
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Evaluation and management of thoracic malignancies including lung,
esophageal and mediastinal tumors
Evaluation and management of surgical lung infections
Staging of thoracic malignancies
Utilize appropriate adjunctive protocols for chemotherapy and radiation
therapy
Intraoperative airway management and planning of major airway
resections
Evaluation, management, and operative treatment of patients undergoing
lung transplantation
Acquire graded intraoperative responsibility as surgeon for operations on
the lung, chest wall, mediastinum and esophagus
Year 1- Related Specialties
Acquire a working knowledge of echocardiography, nuclear cardiology, cardiac
stress tests, pulmonary function studies, chest imaging (CT and MRI), and
esophageal motility. The resident will become sufficiently familiar with these to
be able to independently interpret them.
By the end of the first year, it is the expectation of the Program Director that
the resident is fully capable of performing straightforward cardiac surgery with
minimal assistance. Virtually all general thoracic cases are performed by the
resident with faculty assistance.
Year 2 - Adult Cardiac Surgery
The second year is devoted to the practice of adult cardiac surgery at the
University of Colorado Hospital, the VA Medical Center, as well as gaining
exposure to pediatric cardiac surgery at Children’s Hospital Colorado. It is
expected during the second year that residents will develop an increased
understanding of the following:
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Medical management of heart failure
Indications and contraindications for heart transplantation
Management of heart transplant recipients
Indications for ventricular assist devices
In addition residents will:
Continue to assume more responsibilities as primary surgeon for
operations for myocardial revascularization and valvular heart disease
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Assume responsibility as primary surgeon on heart procurements
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Assume graded responsibility as primary surgeon in the placement of
ventricular assist devices
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Year 2 - Pediatric Cardiac Surgery
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Learn the pathophysiology of the common congenital heart anomalies
Learn the fundamentals of cardiopulmonary bypass in infants and children
Learn the perioperative hemodynamic management for pediatric cardiac
surgical patients
Acquire graded intraoperative responsibility as surgeon for operations to
correct atrial septal defects, ventricular defects, patent ductus arteriosus,
and coarctation of the aorta.
Year 3 - Adult Cardiac and/or General Thoracic Surgery
By the beginning of the third year, the resident is expected to have made a
decision regarding his/her ultimate career goals and subspecialization. Once
this decision has been made and the resident has demonstrated skills to be
ABTS eligible, the resident’s experience is focused in this area. This is
typically for the final six to nine months of the residency. Such areas might
include esophageal surgery, minimally invasive thoracic surgery, valve repair,
etc. In addition, all residents will assume responsibility as primary surgeon on
heart and lung transplants as well as insertion of ventricular assist devices.
Residency Program Continued
Educational Conferences
It is our ultimate goal to prepare our residents, not only to satisfactorily pass
the ABTS certification examination, but to excel beyond that to a level of
expertise that will allow the resident to become a future leader in their area
of specialty. To accomplish this endeavor we have many educational
activities which include:
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Cardiac Catheterization Conferences
Multidisciplinary general thoracic surgical oncology conference (held
weekly with attendance of pulmonologists, oncologists, radiation
oncologists, radiologists, as well as thoracic surgeons)
Surgical Grand Rounds
Morbidity and Mortality Conferences (monthly)
Journal Club held with area cardiothoracic surgeons
Teaching Conferences are held weekly and directed by the thoracic
surgical residents
Research opportunities allowing residents exposure to national
meetings
Case Conferences (monthly)
Residency Case Volume
ABTS
Requirement
2009
Graduate
2010
Graduate
2011
Graduate
2012
Graduate
2013
Graduate
Lungs, Pleura,
Chest Wall,
Diaphragm
50
199
233
218
246
202
Esophagus
25
49
43
22
23
24
Congenital
Heart
20
39
46
42
50
43
Adult Cardiac
Acquired
Valvular Heart
50
125
68
109
140
153
Myocardial
Revascularization
80
111
92
134
139
152
375
727
628
742
833
819
Major
Procedures
Anschutz Medical Campus
The Anschutz Medical Campus (AMC) is a
500 acre campus located 15 minutes from
Denver International Airport. AMC is home to
the newly constructed University of Colorado
Hospital, Children’s Hospital Colorado and the
University of Colorado School of Medicine and
its associated research facilities. It will be the
home of the new Denver Veteran’s Affairs
Medical Center, currently under construction
and schedule for completion in 2015.
The northern 225 acres of the campus are
being developed as the Colorado Science & Technology Park at Fitzsimons, a
biomedical industrial park. More than 30 biotech companies are currently housed
within the more than six million square feet of corporate and bioresearch facility
space. The Denver Regional Transportation District (RTD) has approved a future
light rail line to run from downtown Denver to Denver International Airport with stops
at AMC, further enchancing the connectivity of the Anschutz Medical Campus to the
region.
Teaching Hospitals
As the only academic medical center in the Rocky Mountain region, the University of
Colorado Hospital (UCH) and our top medical professionals, superior medicine, and
progressive change make it one of the leading hospitals in the nation. Consistently
ranked among the top hospitals in the country by U.S. News & World Report’s
annual survey of "America’s Best Hospitals," the University of Colorado Hospital is
internationally respected for its exceptional teams of medical specialists. UCH was
named Top-Performing Academic Hospital in Quality – Two Years in a Row by the
University HealthSystems Consortium.
Located on the Anschutz Medical Campus, the University of Colorado Hospital’s 700
bed hospital contains state of the art facilities including a hybrid operating room in
which TAVR, aortic endovascular and structural heart cases are performed. The 17
bed CT Surgical ICU is located adjacent to the OR, with outpatients seen in the
Cardiovascular Center and in the Cancer Center.
The CT Surgical service at the University of Colorado Hospital encompasses the
surgical treatment of all forms of cardiac, aortic, pulmonary, esophageal and other
thoracic diseases.
The service includes a mature ventricular assist device
component, as well as a full-fledged heart and lung transplant program. All patient
rooms are private and provide facilities for rooming of family members.
Teaching Hospitals Continued
Children’s Hospital Colorado
Pediatric Cardiothoracic Surgery
Children's Hospital Colorado (CHC) has been
ranked for more than a decade as one of the
best children's hospitals nationally in
U.S.News & World Report and is located one
block from the University of Colorado Hospital
on the Anschutz Medical Campus. Its state-of-the-art
facilities include a hybrid operating room and cardiac ICU.
The pediatric cardiac surgical program at CHC
encompasses all forms of complex congenital cardiac
diseases including arterial switch procedures, Norwood procedures and pediatric
cardiac transplantation.
The Department of Veterans Affairs Medical Center
The Department of Veterans Affairs Medical Center, Denver serves as the
tertiary care center for veterans in Colorado, Wyoming, and Montana. All
aspects of adult cardiac and thoracic
diseases are managed by the Denver VA
for this veteran population. There are two
half day clinics devoted to cardiac and
thoracic surgery respectively. The thoracic
surgery resident rotating at the VA
provides coverage at these clinics with our
faculty. There are five operative days per
week. The cardiac caseload is weighted
towards coronary revascularization and
valvular heart disease, although all aspects
of cardiovascular surgery are performed by the cardiothoracic service,
including thoracic aortic aneurysm surgery. The thoracic experience leans
towards surgical management of lung and esophageal carcinomas, as well as
surgical management of pleural infections. The VA experience is a unique and
an integral part of the University of Colorado School of Medicine Thoracic
Surgery Residency Program.
Currently under construction on the
Anschutz Medical Campus, the new state
-of-the-art Denver VA Medical Center
(VAMC) includes a new 120-bed inpatient
bed-tower with a 30-bed spinal cord injury
unit, plus a separate 30-bed nursing
home community living center. The $800
million construction is scheduled for
completion in 2015.
Teaching Hospitals Continued
National Jewish Health
National Jewish Health (NJH) is an accredited teaching
affiliate of the University of Colorado School of Medicine. All
of the physicians and scientists on staff at National Jewish
Health have faculty appointments at the University of
Colorado School of Medicine.
NJH has been recognized as the best respiratory hospital in
the nation since 1998, according to U.S. News & World
Report. NJH has achieved this notable ranking by: 1)
providing patient care that is thorough, multidisciplinary, and tailored to the
individual needs of each patient, 2) “translating” the lessons of world-class
basic science into improvements in patient care, and 3) actively promoting the
continuing education of scientists, physicians, healthcare professionals, and the
public. Patients treated medically at NJH are referred to the University of
Colorado Hospital for thoracic surgical procedures.
Denver Health Medical Center
Denver Health Medical Center is Colorado's primary “safety
net” institution. In the last 10 years, this compassionate
organization provided more than $2.1 billion in care for the
uninsured.
Despite this large financial responsibility,
Denver Health remains financially solvent through an
efficient, integrated system.
25 percent of all Denver residents receive their health care
at Denver Health. One of every three children in Denver is cared for by Denver
Health physicians.
Denver Health is a comprehensive, integrated organization with multiple
components including: 477-bed main hospital at Eighth Avenue and Bannock
Street that houses the Rocky Mountain Regional Level 1 Trauma Center, the
only academic level 1 trauma center in the area; 911 medical response system
for the City and County of Denver; Denver Public Health Department; 8-clinic
network of Family Health Centers throughout the city; 12-clinic network of
school-based health centers in Denver public schools; Rocky Mountain Poison
and Drug Center NurseLine, a telephone advice line that offers assistance to
patients 24 hours a day, seven days a week; Denver CARES, a safe setting
offering community detoxification services; Correctional Care; and Denver
Health Medical Plan, Inc.
Denver Health Medical Center Continued
Denver Health also houses the Denver Health Paramedic School; the Rocky
Mountain Center for Medical Response to Terrorism, Mass Casualties and
Epidemics; the Rita Bass Trauma & EMS Education Institute; the Colorado
Biological, Nuclear, Incendiary, Chemical and Explosive (BNICE) Training Center,
a statewide initiative to educate Colorado's health care and public safety workforce
on the principles of preparing for, and responding to a weapons of mass
destruction event; and clinical training programs for medical residents and allied
health professionals in many different specialties.
Patients treated medically at Denver Health are
referred to the University of Colorado Hospital
for cardiac and thoracic surgical procedures.
Our Faculty
David A. Fullerton, MD
Professor and John T.M. Wright Endowed Chair in Heart
Valve Surgery
Chief, Division of Cardiothoracic Surgery
Residency Program Director
Director, Cardiothoracic Surgical Research
Co-Medical Director, CT Surgical ICU
University of Colorado School of Medicine
Clinical Interests: Myocardial revascularization, valve repair,
valve replacement and TAVR.
Medical School: University of Missouri-Columbia, Magna Cum Laude
Surgery Residency: University of Washington, Seattle
Thoracic Surgery Residency: University of Colorado
Board Certification: American Board of Surgery, American Board of
Surgery—Critical Care, American Board of Thoracic Surgery
David Fullerton, MD was born in Texas and received his undergraduate degree from
Southern Methodist University. He then graduated Magna Cum Laude from the
University of Missouri School of Medicine where he was a member of Alpha Omega
Alpha. He completed a residency in general surgery at the University of Washington
including one year of research in coronary physiology. He then moved to the
University of Colorado for a residency in thoracic surgery which he completed in
1990. He remained on the faculty at the University of Colorado for the next six years
during which time he helped establish adult and pediatric heart and lung transplant
programs. He continued his interest in research and became an NIH-funded
investigator in the area of pulmonary hypertension. During this time he was Chief of
Cardiothoracic Surgery at the Department of Veterans Affairs Medical Center,
Denver. In 1996, he was recruited to Northwestern University in Chicago as Chief of
Cardiothoracic Surgery and Program Director for the thoracic surgery residency
program. After seven very successful years in Chicago, he was recruited back to the
University of Colorado as Head of the Division of Cardiothoracic Surgery.
Dr. Fullerton has received funding from the NIH and has served as a member of the
Surgery, Anesthesia, and Trauma Study Section of NIH. He has published over 200
papers in peer-reviewed journals. He has served on the Editorial Board of The
Annals of Thoracic Surgery, The Journal of Surgical Research and the Journal of
Cardiac Surgery. He is a member of major surgical societies including the Society of
University Surgeons, the American Surgical Association, the Society of Thoracic
Surgeons, the American Association for Thoracic Surgery, the Western Thoracic
Surgical Association, and the Society of Clinical Surgery. He is a past member of the
Board of Governors of the American College of Surgeons. He has been a member of
the Residency Review Committee for Thoracic Surgery and served as the Chair of
that committee. He has served as a Director of the American Board of Thoracic
Surgery. His clinical expertise is recognized by his being listed on numerous “Best
Doctors Lists” over the past decade. He currently serves on the Boards of Directors
for the Joint Council on Thoracic Surgery Education and CTSNet. He is currently the
immediate past president of the STS. He is the Executive Director-elect of the
American Board of Thoracic Surgery.
Ashok N. Babu, MD
Assistant Professor of Surgery, University of Colorado
School of Medicine
Clinical Interests: Surgical treatment of heart failure
with an emphasis on ventricular assist devices. Dr.
Babu’s research interest lies in optimizing the surgical
treatment of heart failure.
Medical School: Northwestern University Medical
School, Chicago
Surgery Residency: University of Colorado
Thoracic Surgery Residency: University of Colorado
Board Certification: American Board of Thoracic Surgery
Ashok Babu, MD is a member of our cardiac surgery faculty in the Division of
Cardiothoracic Surgery. A native of Peoria, Illinois, Dr. Babu attended
Northwestern University where he received his undergraduate degree in
biomedical engineering, graduating summa cum laude with honors. He
continued in the medical program at Northwestern and upon graduation in
2002, moved to the University of Colorado for general surgery training. During
his general surgery training, he spent two years in basic science research
studying lung transplant immunology, esophageal carcinogenesis in reflux
disease, and aortic valve calcification. He received the Ben Eiseman Award for
Basic Science Research in 2007. He also received the J. Cuthbert Owens
Award for Excellence in Teaching and Patient Care and the Golden Apple
Teaching Award during his residency. Upon completion of general surgery
training in 2009, Dr. Babu entered the Thoracic Surgery Residency Program
here at the University of Colorado.
Dr. Babu joined our faculty in July 2012. His clinical interests are wide and
include the surgical treatment of heart failure with short and long term
mechanical circulatory support, extracorporeal membrane oxygenation
(ECMO) for acute respiratory and cardiac failure, minimally invasive valve
surgery, arterial grafting for coronary disease, and quality improvement / cost
reduction in cardiac surgery. His research interests lie in device development
aimed at improving the function and outcomes of ventricular assist devices and
ECMO support.
David N. Campbell, MD
Professor of Surgery, University of Colorado School of
Medicine
Director, Pediatric Cardiac Transplantation Program and
Congenital Cardiac Fellowship Program, Children’s
Hospital Colorado
Medical School: Rush Medical College, Chicago
Surgery Residency: University of Colorado
Thoracic Surgery Residency: University of Colorado
Board Certification: American Board of Thoracic Surgery, American
Board of Thoracic Surgery- Subspecialty Certification in Congenital Cardiac
Surgery.
Dr. Campbell holds the academic rank of Professor of Surgery at the University of
Colorado. He received his medical degree from Rush Medical College. He then
completed residencies in general surgery and thoracic surgery at the University of
Colorado. Dr. Campbell undertook formal fellowship training in pediatric cardiac
surgery at Children’s Hospital Boston. Subsequently, he joined the faculty in the
Department of Surgery at the University of Colorado in 1981.
Dr. Campbell’s major interests include congenital heart surgery, both pediatric and
adult, repair of congenital tracheal diseases, thoracic transplantation in infants,
children and adults, and mechanical circulatory assistance.
Dr. Campbell founded the Heart Transplantation Programs at the University of
Colorado Hospital and at Children’s Hospital Colorado. He continues his
leadership in these fields as the Surgical Director of the Children’s program. Under
his leadership more than 450 heart transplants have been performed in these
programs. He is co-founder of the Pediatric Lung Transplant Program at
Children’s Hospital Colorado. He also founded the Mechanical Circulatory Support
Program at the University of Colorado Hospital.
Dr. Campbell is certified by the American Board of Thoracic Surgery, and holds a
Specialty Certificate in Congenital Heart Surgery. He is a member of 18
professional societies including the American Association of Thoracic Surgery, the
Society of Thoracic Surgeons, the Western Thoracic Surgical Association, the
International Society for Heart and Lung Transplantation, American College of
Surgeons, and the Congenital Heart Surgeons Society. Dr. Campbell is active in
the leadership of several local medical organizations, as well as regional and
national organizations.
Dr. Campbell has authored more than 25 book chapters and has authored or coauthored more than 125 scientific papers published in peer-reviewed journals. Dr.
Campbell is widely regarded as an influential surgical educator and is the Director
of the ACGME-approved Congenital Cardiac Surgery Residency Program.
Joseph C. Cleveland, Jr, MD
Professor of Surgery, University of Colorado School of
Medicine
Clinical Interests: Adult cardiac surgery, off-pump
coronary artery surgery, adult heart and lung
transplantation, mechanical assist devices, heart valve
reconstruction/replacement.
Medical School: University of Washington, Seattle
Surgery Residency: University of Colorado
Thoracic Surgery Residency: University of Colorado
Board Certification: American Board of Surgery, American Board of
Thoracic Surgery
Dr. Cleveland joined the Cardiothoracic Surgery faculty July 2001. He is a Professor of
Surgery. He attended medical school at the University of Washington where he was
elected to Alpha Omega Alpha graduating with High Honors in 1991. He completed an
internship, surgery residency and thoracic surgery residency at the University of
Colorado from 1991– 2001.
Dr. Cleveland’s clinical interests include adult cardiac surgery, adult heart and lung
transplantation, mechanical assist devices, and heart valve reconstruction/replacement.
He is the Surgical Director for Adult Cardiac Transplantation/Mechanical Assist Devices
at the University of Colorado Hospital. Dr. Cleveland is a nationally recognized expert of
ventricular assist devices (VAD) and is a member of the end-stage cardiopulmonary
disease workforce of the STS. He also is a member of the Adverse Effects Committee
for Intermacs, a NIH sponsored VAD database.
Dr. Cleveland’s research interests concern myocardial responses to cardiopulmonary
bypass and obligatory ischemia associated with heart surgery. He completed a twoyear trauma surgical research fellowship under the mentorship of Alden H. Harken,
M.D. from 1994 to 1996. During that time he worked on cellular signaling during
myocardial preconditioning. Dr. Cleveland was a recipient of the Jahnigen Career
Development Award from the American Geriatric Society in 2004. He is the Principal
Investigator/Co-Principal Investigator on numerous clinical research studies and has
authored or co-authored over 100 publications and 15 book chapters.
Dr. Cleveland is the Assistant Program Director of the Thoracic Surgery Residency
Program and is a Preceptor in the Foundations of Doctoring Program. He received the
Outstanding Clinical Teacher award for 2002-2003, the first annual School of Medicine
Professionalism Award in 2007, in 2009 was a co-recipient of the 5th Annual Dwight
McGoon National Teaching Award presented at the AATS, and in 2010, 2012, 2013 &
2014 was recognized in 5280: Denver’s Mile High Magazine as one of Denver’s Top
Doctors.
Dr. Cleveland is a member of The Society of Thoracic Surgeons, the American
Association for Thoracic Surgery, the American College of Surgeons and numerous
other societies. He is on workforces for the STS, is treasurer of the WTSA, and serves
on numerous other society and local committees. He is the program chair for the 51st
Annual STS Meeting in January 2015.
Frederick L. Grover, MD
Professor of Surgery, Division of Cardiothoracic Surgery and
Past Chair, Department of Surgery, University of Colorado School of
Medicine
Clinical Interests: Adult cardiac surgery, lung transplantation,
adult heart transplantation.
Medical School: Duke University
Surgery Residency: Duke University Medical Center, University
of Colorado
Thoracic Surgery Residency: University of Colorado
Board Certification: American Board of Surgery, American Board Thoracic Surgery
From 1991 to 2003, Dr. Grover was Head of the Division of Cardiothoracic Surgery at the
University of Colorado School of Medicine and Chief of Surgical Services at the Department
of Veterans Affairs Medical Center, Denver. From August 2002 until May 2012, Dr. Grover
was Chair of the Department of Surgery at the University of Colorado School of Medicine. He
is a graduate of Duke University School of Medicine. He obtained his residency training at
Duke University and the University of Colorado. Following two years of military service in the
U.S. Navy in San Diego, Dr. Grover spent 19 years of his career in San Antonio at the
University of Texas Health Science Center in the Division of Cardiothoracic Surgery.
Dr. Grover has a major interest in general and cardiothoracic residency training. He has
actively participated in the training and mentoring of over 44 thoracic surgery residents over
his career. In addition to clinical interests in the areas of acquired adult cardiac surgery and
lung and heart transplantation, Dr. Grover has a major interest in risk-adjusted outcomes
analyses and quality improvement in the field of cardiothoracic surgery. He chaired the
Society of Thoracic Surgeons Work Force on National Databases from 1995 to 2004. In
addition, he was the Medical Director of the Continuous Improvement in Cardiac Surgery
Program for the Department of Veterans Affairs and in that capacity helped organize the VA
Cardiac Surgery Database. He chaired the United Network for Organ Sharing Thoracic
Committee, and has served on the UNOS Board of Directors. He was the Co-Principal
Investigator of a large VA multi-center clinical trial comparing off-pump to on-pump coronary
artery bypass, which was published in the New England Journal of Medicine.
Dr. Grover belongs to numerous professional organizations including the American Medical
Association, American College of Surgeons, Society of Thoracic Surgeons, American
Association for Thoracic Surgery, the Southern Thoracic Surgical Association, American
Surgical Association, the Western Thoracic Surgical Association, the European Association
for Cardiothoracic Surgery, the Society of University Surgeons, the International Society for
Heart and Lung Transplantation, and is a past-president of the Southern Thoracic Surgical
Association. Dr. Grover served as President of the Society of Thoracic Surgeons for 2006 –
2007. He has served on the National Quality Forum Board of Directors, and currently serves
on the American College of Cardiology National Cardiovascular Data Registry Board, and
was Chair of the STS Council on Quality, Research, and Patient Safety. Dr. Grover has been
very involved in healthcare policy at a national level and is an advocate for physician
involvement and leadership in this effort. He has authored or co-authored over 312 scientific
papers, many of which are in the area of utilizing surgical databases for quality improvement.
He was honored in 2005 by receiving the Duke University Distinguished Medical Alumnus
Award, by being the 2010 ACS Gibbon Lecturer, by receiving the American College of
Cardiology Distinguished Fellowship Award, the University of Colorado Faculty
Professionalism and Jefferson Awards, the Association of VA Surgeons Distinguished
Service Award and the Southern Thoracic Surgical Association Inspiration Award and is an
American Heart Association Fellow. Dr. Grover serves on a national not-for-profit board and
has an interest in international medicine and medical missions in developing countries.
Dr. Grover and his wife of 54 years Carol have two sons and four grandchildren and two
exceptional daughter-in laws, all of whom live in Denver. For relaxation he enjoys the
outdoors and especially fly fishing and skiing.
James Jaggers, MD
Professor of Surgery, University of Colorado School of
Medicine
Barton-Elliman Chair and Chief of Pediatric Cardiac
Surgery
Children’s Hospital Colorado
Clinical Interests: Complex congenital heart defects in
newborns and infants, adult congenital cardiac surgery,
pediatric cardiac transplantation, surgery for Marfan
Syndrome.
Medical School: University of Nebraska
Surgery Residency: Oregon Health Sciences University
Thoracic Surgery Residency: University of Colorado
Board Certification: American Board of Surgery, American Board of
Thoracic Surgery, Congenital Cardiac Surgery
A native of Nebraska, Dr. Jaggers is a graduate of the University of Nebraska
School of Medicine. Following a residency in surgery at the University of Oregon,
he completed a residency in cardiothoracic surgery at the University of Colorado
in 1996 and a post-graduate fellowship at Children’s Hospital Colorado in 1993
and 1996.
In early 2010, Dr. Jaggers was recruited from Duke University Medical School,
where he served as a faculty member in the Department of Surgery since 1996
and Chief of Pediatric Cardiothoracic Surgery since 2001.
Dr. Jaggers is the Barton-Elliman Chair in Pediatric Cardiothoracic Surgery and
Co-Medical Director of the Heart Institute at Children’s Hospital Colorado. Dr.
Jaggers specializes in repairing complex congenital heart defects in babies and
newborns and is also among the first to receive a new subspecialty certification in
congenital cardiac surgery designated by the American Board of Thoracic
Surgery. He is also a leading authority in neonatal heart surgery. In addition to
his skill as a clinical surgeon, Dr. Jaggers is a highly respected researcher whose
work has appeared in nearly 100 scientific publications and books. Dr. Jaggers’
interests include clinical research in the performance and quality of Congenital
Heart Surgery, as well as basic science research in mechanisms of development
for Left Heart Obstruction Defects.
Dr. Jaggers is a member of 12 professional organizations including the American
Association for Thoracic Surgery, the American College of Surgeons, the
Congenital Heart Surgeons Society, the International Society for Heart & Lung
Transplantation, the Society of Thoracic Surgeons, the European Association of
Cardiothoracic Surgery, and the World Society of Pediatric Cardiac Surgeons.
Robert A. Meguid, MD, MPH
Assistant Professor of Surgery
Medical Degree: Brown University, Providence, RI
Surgery Residency: Johns Hopkins University,
Baltimore
Thoracic Surgery Residency: University of
Washington, Seattle
Board Certification: American Board of Surgery, American Board of
Thoracic Surgery
Dr. Meguid received his undergraduate degree in biochemistry from Brown University
in Providence, Rhode Island and graduated with honors in 1997. He received his
medical degree in 2002 from Brown University School of Medicine. He performed his
internship and residency in general surgery at the Johns Hopkins Hospital, Baltimore,
Maryland between 2002 and 2010. Following completion of his general surgery
residency, he undertook his cardiothoracic surgery residency at the University of
Washington, Seattle, Washington, between 2010 and 2012.
He obtained a Master of Public Health with a focus in epidemiologic and biostatistics at
the Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland
in 2008, during which time he completed a thoracic surgery research fellowship.
Throughout his formal education, he has engaged in research training as a research
fellow in the Surgical Nutrition and Metabolism Laboratory at the SUNY Health Science
Center in Syracuse, New York, the Center for Surgical Research at the Brown
University School of Medicine in Providence, Rhode Island, and in the Surgical
Oncology Research Laboratory at Massachusetts General Hospital, Harvard Medical
School, in Boston, Massachusetts.
Dr. Meguid joined our faculty in July 2012. His clinical interests include benign and
malignant diseases of the lung, esophagus and mediastinum; chest wall tumors,
deformities and reconstruction; surgery for end-stage lung disease and lung
transplantation; benign and malignant airway disease; and minimally invasive thoracic
procedures such as VATS lobectomy.
Dr. Meguid is the surgical director of the Surgical Outcomes and Applied Research
(SOAR) program, a research collaborative between the Department of Surgery and the
University of Colorado Adult and Child Center for Health Outcomes Research and
Delivery Science. His research is in identifying structures and processes of care which
lead to improved outcomes for surgical patients, in order to improve patient care and
shape health care policy. Dr. Meguid is a member of The Society of Thoracic
Surgeons, the American College of Surgeons, the Society of Surgical Oncology, the
Association for Academic Surgery, the Surgical Outcomes Club and other professional
organizations. He is engaged in medical student and resident training and mentorship.
He is an editor-in-chief of The Johns Hopkins ABSITE Review, author of several
chapters and numerous research articles in the field of thoracic surgery, for which he
has received national recognition.
John D. Mitchell, MD
Professor of Surgery
Courtney C. and Lucy Patten Davis Endowed Chair in
Thoracic Surgery
Chief, Section of General Thoracic Surgery
University of Colorado School of Medicine
Medical Degree: University of Michigan, Ann Arbor
Surgery Residency: Massachusetts General Hospital, Boston
Thoracic Surgery Residency: Massachusetts General Hospital, Boston
Board Certification: American Board of Surgery, American Board of
Thoracic Surgery
A native of Colorado, Dr. Mitchell received his undergraduate degree in
molecular biology at the University of Colorado Boulder, graduating Magna Cum
Laude in 1983. He subsequently attended the University of Michigan Medical
School on an Armed Forces Scholarship, graduating in 1987 with honors and as a
member of Alpha Omega Alpha. He then moved to Boston, where over the
following decade he completed residencies in both General and Cardiothoracic
Surgery at Massachusetts General Hospital. During his residency, Dr. Mitchell also
served as a Registrar in Cardiothoracic Surgery in Liverpool, England, and was a
research fellow at Harvard Medical School from 1990 to 1992. Following a four
year period on active duty in the United States Navy, Dr. Mitchell joined the faculty
at the Stanford University School of Medicine. In 2002, he was recruited to the
University of Colorado to become the Chief of General Thoracic Surgery. Since his
arrival in Colorado, he has been recognized repeatedly by his peers as one of the
best thoracic surgeons in the Rocky Mountain region. In 2006, Dr. Mitchell was
awarded the Courtenay C. and Lucy Patten Davis Endowed Chair in the
Department of Surgery, and in 2008 was presented the Donald B. Doty Educational
Award at the 34th Annual Western Thoracic Surgical Association.
Dr. Mitchell is the Chief of General Thoracic Surgery within the Division of
Cardiothoracic Surgery. His primary clinical responsibilities are at the University of
Colorado Hospital and National Jewish Health, Denver. As a consultant for
National Jewish, Dr. Mitchell has extensive experience in the surgical treatment of
lung infection. His research interests focus on lung cancer, surgical treatment of
lung infection, and lung transplantation. His clinical interests include all thoracic
oncology, surgery of the airway, surgery for infectious lung disease, esophageal
surgery, adult lung transplantation, and minimally invasive approaches to thoracic
surgical procedures.
Dr. Mitchell is a member of the Society of Thoracic Surgeons, the American
College of Surgeons, the American Association for Thoracic Surgery, the Western
Thoracic Surgical Association, the General Thoracic Surgical Club and numerous
other professional groups. He currently serves on the ACS Board of Governors
and the ACS Advisory Council for Cardiothoracic Surgery, as well as several STS
Committees including the Council on Quality, Research and Patient Safety, the
Committee on Ethics and Standards, and is the Chair of the STS Workforce on
Evidence Based Surgery. He is President Elect of the WTSA, the past Treasurer
and Program Chair of the WTSA, and serves on the Executive Committee of the
Max B. Mitchell, MD
Professor of Surgery, University of Colorado School of
Medicine
Clinical Interests: Congenital heart disease, pediatric
heart transplantation, adult congenital heart disease.
Medical School: George Washington University
Surgery Residency: University of Colorado
Thoracic Surgery Residency: University of Colorado
Pediatric Cardiac Surgery Fellowship: Royal Children’s Hospital,
Melbourne, Australia
Board Certification: American Board of Surgery, American Board of
Thoracic Surgery, American Board of Thoracic Surgery- Subspecialty
certification in Pediatric Cardiac Surgery
Dr. Mitchell holds the academic rank of Professor of Surgery at the University of
Colorado. Dr. Mitchell received his Doctorate in Medicine from the George
Washington University School of Medicine. He then completed residencies in
General Surgery and Thoracic Surgery at the University of Colorado. Dr. Mitchell
conducted basic science research during a full-time two-year National Institutes of
Health Postdoctoral Research Fellowship in the surgical laboratory at the University
of Colorado. Dr. Mitchell undertook fellowship training in pediatric cardiothoracic
surgery for one year at the Children’s Hospital Colorado, and subsequently served
as the senior fellow in pediatric cardiothoracic surgery at the Royal Children’s
Hospital in Melbourne, Australia. He has been a faculty member in the Department
of Surgery at the University of Colorado since 1998. He is the Director of the
Mechanical Circulatory Support Program at the Children’s Hospital Colorado.
Dr. Mitchell’s clinical interests include neonatal and congenital cardiac surgery,
congenital and acquired diseases of the mitral valve, atrioventricular valve repair in
children and adults, and pediatric cardiac transplantation. His basic research
interests include myocardial preservation and endothelial cell function. He is
currently conducting clinical projects studying outcomes following a variety of
congenital cardiac surgical conditions. In addition, Dr. Mitchell has ongoing studies
examining biologic differences between normal and pathologic heart valves in
pediatric patients. He has authored or co-authored 62 peer reviewed articles and 21
invited papers or book chapters. Dr. Mitchell has made scientific presentations at
more than 16 national and international meetings, and he has given invited lectures
in Japan, China and Spain. Dr. Mitchell has an interest in third world medicine and
has participated on volunteer medical missions in Kazakhstan and China. Dr.
Mitchell has served in Iraq as a military surgeon.
Dr. Mitchell is a member of 11 professional organizations including the Congenital
Heart Surgeons Society, the American Association for Thoracic Surgery, the Society
of Thoracic Surgeons, the Western Thoracic Surgical Association, and the
European Association for Cardio-Thoracic Surgery.
T. Brett Reece, MD
Associate Professor of Surgery, University of Colorado School of
Medicine
Interests: Adult cardiac surgery, thoracic aortic
surgery, aortic endografting, aortic dissections, aortic valve
preservation, interstitial aortic diseases including the Marfan’s
and bicuspid aortic valve syndromes, mechanical circulatory
support, and thoracic transplantation.
Clinical
Medical School: University of Virginia
Surgery Residency: University of Virginia
Thoracic Surgery Residency: University of Colorado
Aortic Surgery Fellowship: University of Pennsylvania
Board Certification:
Thoracic Surgery
American Board of Surgery, American Board of
T. Brett Reece, MD serves as cardiac surgery faculty in the Division of
Cardiothoracic Surgery. He grew up in Oklahoma playing football and ranching. After
earning his BA in economics from Dartmouth College, he received his medical
degree at the University of Virginia, where he completed his surgical research
fellowship and general surgery training in 2006. His next step was completion of his
thoracic surgery training at the University of Colorado in 2009 in addition to a
fellowship in aortic surgery at the University of Pennsylvania in the spring of 2008.
Dr. Reece has wide interests in cardiac surgery, including mechanical circulatory
support and thoracic transplantation. However, his main interest lies in the Thoracic
Aortic Program at the University of Colorado. This multidisciplinary program
encompasses all approaches to thoracic aortic disease including open procedures,
endovascular procedures, hybrid procedures, and hypothermic circulatory arrest.
Moreover, the program has an aggressive approach toward the treatment of aortic
dissections, both short and long term. The newly structured Thoracic Aortic Clinic
serves all thoracic aortic pathology including genetic pathologies such as Marfan’s
and other interstitial arterial diseases.
During his training, Dr. Reece learned the value of medical student and resident
education. His interest in surgical education is evident by multiple education and
leadership awards from both UVA and the University of Colorado. He serves as the
Associate Director for Medical Student Education in the Department of Surgery. He
also serves on the Thoracic Surgery Directors Association’s Cardiac Curriculum
Committee and as Topic Editor for thoracic aortic surgery for the American Board of
Thoracic Surgery Curriculum.
On the research side, Dr. Reece has developed murine models of paraplegia related
to thoracoabdominal operations. This line of research includes both the in vivo and in
vitro models of spinal cord injury pursuing novel clinical techniques for preventing
spinal cord injury resulting from aortic surgery. Clinically, thoracic aortic research
has explored less invasive ways and safer techniques for caring for complex aortic
pathologies.
Michael J. Weyant, MD
Associate Professor of Surgery, University of Colorado
School of Medicine, Surgical Director, Lung
Transplantation
Medical School: Mount Sinai School of Medicine, New
York
Surgery Residency: New York-Presbyterian Hospital and
Weill Medical College of Cornell University
Thoracic Surgery Residency: Memorial Sloan-Kettering
Cancer Center and New York-Presbyterian Hospital
Board Certification: American Board of Thoracic Surgery, American Board
of Surgery
Fellow: American College of Surgeons
Michael J. Weyant, MD received an undergraduate degree in biology from Syracuse
University, and graduated from the Mount Sinai School of Medicine in New York. He
completed a residency in general surgery at the New York-Presbyterian Hospital and
Weill Medical College of Cornell University. During his residency he completed a twoyear research fellowship studying areas of basic science in surgical oncology. In his final
year of residency he was selected as the Chief Surgical Resident in the Department of
Surgery. Dr. Weyant continued his training in New York, entering a fellowship in thoracic
surgery at Memorial Sloan-Kettering Cancer Center and Weill Medical College of Cornell
University.
Dr. Weyant joined the faculty of the University of Colorado School of Medicine in July
2005. His practice is dedicated to all areas of general thoracic surgery including
thoracic malignancies, benign esophageal disease, minimally invasive thoracic
procedures, and lung transplantation.
Since joining the faculty he has developed a busy clinical practice as well as initiating
laboratory research in the areas of esophageal malignancy, lung carcinoma, and lung
transplantation. His success in the laboratory is evident by multiple publications and
meeting presentations regarding his research. His work was recognized by receiving the
2007 Norman E. Shumway Award and mentoring one of his research residents toward
the Samson award in the Western Thoracic Surgical Association Annual Meeting. He
has since mentored several surgery residents pursuing research fellowships who have
demonstrated excellence through many publications and awards.
Dr. Weyant is recognized as an outstanding educator by his medical student and
resident colleagues. He is the 2008 recipient of the University of Colorado Medical
Student Golden Apple Teacher of the Year Award and the 2010 recipient of the McGoon
Award. The latter is a national teaching award given by the American Association of
Thoracic Surgery recognizing excellence in the teaching of cardiothoracic surgery
residents. In 2007, Dr. Weyant received the Gary L. and Thelissa Zollinger Early
Detection of Lung Cancer Endowment. This significant contribution enables Dr. Weyant
to pursue areas of research in early detection of lung cancer as well as interact with the
local community to raise awareness of the impact of lung cancer.
Dr. Weyant is an active member of The Society of Thoracic Surgeons and is a member
of several workforce committees including the General Thoracic Workforce and the Task
membership Committee. He was the 2008-2009 WTSA Chair for the Arrangements
Committee and currently serves as the Chair of the Membership Committee of the
WTSA.
Our Thoracic Surgery Residents
David Mauchley, MD
Chief Resident
General Surgery Residency: University of Colorado
Medical School: University of Washington
Justin Reeves, MD
2nd Year Resident
General Surgery Residency: Dartmouth-Hitchcock
Medical Center
Medical School: University of North Carolina
Ryan Shelstad, MD
2nd Year Resident
General Surgery Residency: University of Minnesota
Medical School: University of Nebraska
Edward (Ed) Bergeron, MD
1st Year Resident
General Surgery Residency: Oakland
University William Beaumont School of
Medicine, Royal Oak, MI
Medical School: Wayne State University
School of Medicine
Giorgio Zanotti, MD
1st Year Resident
General Surgery Residency: Duke University
Medical School: Universita di Pavia, Italy
Our Future Thoracic Surgery Residents
Charles Cole, MD
Starts Training 7/2015
General Surgery Residency: University of Cincinnati
Medical School: University of Arkansas for Medical Sciences
College of Medicine
Brendan Dewan, MD
Starts Training 7/2015
General Surgery Residency: Emory University
Medical School: The University of Texas School of Medicine at
San Antonio
Our Congenital Cardiac Surgery Fellow
Weng Koon Edward Peng, MD,
Fellow, Pediatric Mechanical Support and Pediatric Cardiac
Transplantation
Thoracic Surgery Residency: Royal Hospital for Sick Children
(Yorkhill, Glasgow, UK)
General Surgery Residency: Queen Margaret Hospital (Fife, UK)
Medical School: University of Malaya (Kuala Lumpur, Malaysia)
Former Residents
From 1977 through 2012, 36 residents completed the three-year training program at the
University of Colorado. Nineteen of these residents initially took academic positions. The
remaining are practicing from Idaho to Florida. All of our residents who have taken both
parts of the American Board of Thoracic Surgery exam have become board certified.
With the teaching system instituted by Dr. David Fullerton, residents are able to spend
more of their residency in the area they intend to practice while still obtaining the index
case requirements of the American Board of Thoracic Surgery. All areas of cardiothoracic
surgery are experienced in our residency program. Adult cardiac, pediatric cardiac,
general thoracic, and transplant are well covered in the three-year program.
Our well-rounded program has enabled residents to be independent surgeons either in
private practice or academia once the residency has been completed.
Stan Carson, MD - 1977
Private Practice, Denver, CO
David Campbell, MD - 1979
Professor, Children’s Hospital Colorado,
Aurora, CO
Richard Phillips, MD - 1980
Volunteer, Washington State University
Frank Manart, MD - 1981
Private Practice, Vail, CO
Lawrence Patzelt, MD - 1982
Private Practice, Grand Rapids, MI
John C. Heiser, MD - 1983
Private Practice, Grand Rapids, MI
Thomas Cain, MD - 1984
Private Practice, Green Bay, WI
Douglas Cowgill, MD - 1985
Dean, Clinic/St. Mary’s Hospital, Madison, WI
Fred Woelfel, MD - 1986
Private Practice, Pittsburgh, PA
Mark Ammons, MD - 1987
Private Practice, Denver, CO
Glenn Whitman, MD - 1988
Professor, John Hopkins University
Mike See, MD - 1989
Private Practice, Columbia, MO
David Fullerton, MD - 1990
Professor, University of Colorado
John C. St. Cyr, MD - 1991
Medical Consultant, Minnesota
James Albert, MD - 1992
Private Practice, Colorado Springs, CO
Michael Grosso, MD - 1993
University of Pennsylvania, Philadelphia
James Brown, MD - 1994
Associate Professor, University of Maryland
Steve Jones, MD - 1995
Private Practice, Boise, ID
Jim Jaggers, MD - 1996
Professor, Children's Hospital Colorado,
Aurora, CO
Mary Wollerming, MD - 1997
Skaggs Medical Center, Branson, MO
Max Mitchell, MD - 1998
Professor, Children's Hospital Colorado,
Aurora, CO
Irving Shen, MD - 1999
Professor, University of Oregon
Peter Seirafi, MD - 2000
Private Practice, Sebastian, FL
Joseph Cleveland, MD - 2001
Professor, University of Colorado
Brett Sheridan, MD - 2002
Associate Professor, University of North Carolina
Craig Selzman, MD - 2003
Associate Professor, University of Utah
Larry Brinckerhoff, MD - 2004
Assistant Professor, Tufts University
Tim Sherwood, MD - 2005
Private Practice, Frederick, MD
Aditya Kaza, MD - 2006
Associate Professor, Boston Children’s Hospital
Sunil Malhotra, MD - 2007
Assistant Professor, New York University
Gonzalo Carrizo, MD - 2008
Instructor, University of Florida
T. Brett Reece, MD - 2009
Associate Professor, University of Colorado
John Charles Dugal, Jr., MD - 2010
Private Practice, Knoxville, TN
Ramesh Singh, MD– 2011
Inova Fairfax Hospital, Falls Church, VA
Ashok Babu, MD—2012
Assistant Professor, University of Colorado
Sagar Damle, MD—2013
Nebraska Heart Hospital . Lincoln, NE
Mathéau A. Julien, MD, PhD—2014
Visiting Assistant Professor, University of
California, Davis
Mechanical Circulatory Support
at the University of Colorado Hospital
The Mechanical Circulatory Support (MCS) Program at the University of
Colorado Hospital provides access to life-sustaining devices that are used
to treat patients with acute and end-stage heart failure. Patients are
managed by the Cardiothoracic Surgery Service while they are inpatients
and followed on an outpatient basis by the Heart Failure Service. There is
a Mechanical Support Coordinator on call 24 hours a day, seven days a
week available to patients and staff. We currently have over 60 patients
supported on long-term devices.
The MCS Program grew from a longstanding partnership with our surgical
program for advanced surgical therapies in conjunction with an active
heart failure cardiology service. Dr. Joseph Cleveland serves as the
Surgical Director of the MCS Program; Dr. Andreas Brieke serves as the
Medical Director. Dr. Ashok Babu has recently been recruited to the
faculty as a second surgeon with an active role and interest in MCS and is
also developing our ECMO program. Dr. Cleveland also serves nationally
on the INTERMACs Adverse Event Adjudication Committee.
Devices are placed for three different indications: Recovery, Bridge to
Transplant (BTT), and Destination Therapy (DT). Currently at UCH we
implant the CentriMag, Impella 5.0, Thoratec IVADs and PVADs, Thoratec
HeartMate II, and the Heartware HVAD. UCH has been an active
participant in both Heartmate II and the Heartware BTT and DT Clinical
Trials.
On July 23, 2008, the University of Colorado Hospital was awarded Joint
Commission Disease Specific Certification for DT Ventricular Assist Device
Therapy, the 14th hospital in the country to be awarded this certification.
We recently received our fourth Joint Commission Re-Certification for DT
VAD.
There is a multi-disciplinary team that participates in the evaluation and
management of these patients. Our CT Surgery Residents are actively
involved in the
The Mechanical Circulatory
evaluation,
Support Program at UCH has
implantation, and
earned the Joint Commission's
post-implantation care Gold Seal of ApprovalTM for
health care quality and diseaseof our VAD patients.
specific certification for VADs
for Destination Therapy. The
Joint Commission is the nation's
oldest and largest standardssetting and accrediting body in
health care.
Thoracoscopic (Minimally Invasive)
Lung and Esophageal Resection at
University of Colorado Hospital
Introduced in the mid to late 1990s, thoracoscopic techniques (video-assisted
thoracoscopic surgery, or VATS) have become the standard of care for
anatomic lung resection in North America. As such, it is imperative that
trainees in cardiothoracic surgery gain significant experience in these
techniques. At the University of Colorado, approximately 75% of anatomic
lung resections (segmentectomy, lobectomy, bilobectomy) are performed via
a minimally invasive approach. Exposure to these skills begins with the
resident’s first rotation on the Thoracic Service, and continues to the
completion of the training program. The high volume of cases typically leads
to proficiency quickly, and it is expected that finishing residents be
comfortable performing these cases in an independent fashion.
In addition to resections performed for malignancy, additional experience is
gained through our Infectious Lung Disease Program run jointly with
clinicians at National Jewish Health. Through this program, patients from
across the United States come to Denver for evaluation regarding treatment
for bronchiectasis, cavitary lung disease and other related disorders.
Patients for whom surgery (anatomic lung resection) may be beneficial are
seen at presentation, then scheduled for surgery at the University of
Colorado. As a result, residents gain experience in a large volume of VATS
resections, often intricate in nature – segmentectomy or removal of multiple
segments, with routine use of thoracoscopic muscle flap transposition. Of
course, not all of these patients are eligible for minimally invasive surgery,
and this same program allows for exposure to the most complex and difficult
types of lung resection – often with concomitant thoracoplasty or Eloesser
flap creation.
Similar to the VATS program, our
residents gain considerable experience
in minimally invasive esophagectomy
techniques,
largely for
malignant
disease. Over the last 2 to 3 years, the
clear majority of esophageal resections
at our institution have been performed
utilizing this approach, with excellent
results.
Again, the large number of
cases assures residents of sufficient
exposure to perform these cases in an
independent manner by completion of
the training program.
ECMO Program at University of
Colorado Hospital
The ECMO program at UCH has been rapidly growing over the past several
years both in the area of acute cardiogenic shock as well as in acute
respiratory failure and bridge to lung transplantation. We are currently
performing about 30 plus cases per year for various indications. Our
outcomes have been excellent and have bolstered volumes for durable
LVAD, heart transplant, and lung transplant by turning these critically ill
patients into candidates for those therapies. We continue to perform
outreach to attempt to grow the “hub and spoke” model for ECMO transfer
and are developing a program to allow ECMO transport in the region. The
residents gain significant experience in cannulation for VA ECMO, VV ECMO,
Avalon cannula, and left ventricular venting as well as in the management of
these complex patients. Dr. Ashok Babu serves as the medical director of
the ECMO program in collaboration with the pulmonary critical care group
and the heart failure cardiologists.
Thoracic Aortic Program at University
of Colorado Hospital
The Thoracic Aortic Program at the University of Colorado has developed into
a nationally recognized entity. Since 2009, the program has grown from
isolated dissection cases with a smattering of elective procedures to a true
multidisciplinary program offering the full spectrum of open and endovascular
interventions from the root through the iliac arteries. The Thoracic Aortic
Clinic facilitates the evaluation of patients with Marfans Syndrome, interstitial
vascular disease, and familial aneurysmal syndrome. The care of these
patients is shared among cardiothoracic surgery, vascular surgery, and
cardiology. This collaboration has expanded the aortic root procedures being
done and allowed for the volume to push Aortic Valve repair and Valve
sparing root or David procedures. The aggressive approach towards
ascending aneurysmal disease has led to >50 hypothermic circulatory arrest
cases per year. The program participates in the IRAD and represents in the
Society of Thoracic Surgeons Advanced TEVAR symposia. The
endovascular program has grown from a few stent grafts a year to more than
40 per year. In conjunction with vascular
surgery,
the
thoracoabdominal
endovascular program has begun with
physician
modified
endografts.
Essentially, there is no aortic procedure
that is not done at the University of
Colorado. Residents will learn a simple,
safe approach to these complex
anatomic repairs. Graduating fellows
have essentially done an aortic superfellowship after three years at the
University of Colorado.
TAVR Program at the University of
Colorado
The TAVR program at the University of Colorado is very active and currently
performs approximately 2-3 cases per week. It is a multi-disciplinary program
in all regards. The procedures are performed in the hybrid operating room by
a team from cardiac surgery and interventional cardiology. Patients referred
for consideration of TAVR are evaluated in the Valve Clinic jointly by
surgeons and cardiologists. The TAVR program in an active participant in
clinical trials pertaining to TAVR, including the Partner II trial.
Treatment of End Stage Lung Disease
at the University of Colorado
The University of Colorado Hospital is the only center in the region that
performs comprehensive treatment of end stage lung disease. The lung
transplant program performs approximately 30-40 lung transplants per year.
The cardiothoracic surgery residents participate in all levels of this program
including performing implantation of organs and procurement procedures.
We are also one of the few centers in the United States performing ex-vivo
lung perfusion as a modality to improve and identify additional lung donor
organs. The program actively engages in the use of the available mechanical
lung assist devices such as venovenous and arteriovenous ECMO. Lastly we
are the only designated referral center in the region that performs lung
volume reduction surgery.
Airway Surgery Program at University
of Colorado Hospital
Due to our geographic location, faculty interest, and collaboration with
National Jewish Health, the University of Colorado serves as a major referral
center for airway disease in the central United States. Trainees within the
Thoracic Surgery program gain considerable experience in both endoscopic
and open surgical approaches in the management of these challenging
patients. Mastery of the basic surgical techniques used in airway surgery is
expected of our finishing residents, and these techniques serve as the
foundation for successful completion of any airway procedure as they move
into independent practice.
A variety of endoscopic therapies for both benign and malignant disease are
emphasized throughout the training program. Residents gain appreciable
experience in both flexible and rigid bronchoscopy, and become expert in
complex airway management. Additional experience, if desired, may be
arranged with rotations with our interventional pulmonology staff.
In addition to the standard bronchial sleeve resection techniques utilized with
lung malignancies, residents see and operate on a considerable number of
patients with benign tracheal and laryngotracheal stenosis. Indeed, over the
last decade laryngotracheal resection and reconstruction for subglottic
stenosis has become the most common airway procedure performed at our
institution. Experience with these airway surgical techniques, although
common within our program, remains rare in the majority of thoracic
residencies nationwide.
Beyond endoscopic therapies and airway resection, a third component of our
airway program involves surgical correction of central airway collapse, or
tracheobronchial malacia. Patients who are found to have symptomatic
airway malacia by bronchoscopic and dynamic CT imaging are given a trial of
airway stenting; if the symptoms are relieved, they are offered surgical
tracheobronchoplasty. Our program to address airway malacia, coordinated
with colleagues at National Jewish, is one of the largest in the country.
Clinical Research
Activities
Members of the Division of Cardiothoracic
Surgery play an active role in clinical research at
the University of Colorado School of Medicine.
Surgical Outcomes and Applied Research (SOAR) is a formal commitment by the
Department of Surgery in collaboration with the University of Colorado Adult and
Child Center for Health Outcomes Research and Delivery Science to establish a
leading program in surgical outcomes research. Members engage in weekly
research meetings with ongoing projects and grant applications to achieve selfsupported research. In addition to formal meetings, SOAR provides drop-in office
hours to help with project design and provide statistical guidance.
Clinical Trials Research
In addition, the members of the Division of Cardiothoracic Surgery are involved in
clinical trials research, ranging from:
 Contribution to the Lung Cancer Tumor Bank SPORE
 The PARTNER Trial of TAVR (vs) Surgical AVR
 The Endurance Trial (Heartware HVAD )
 Sorin Perceval Valve Trial
 VA grant for long term follow up of on and off pump patient groups
 RADIANT Trial: A Multi-center, Randomized, Double-blind, Placebo
controlled, Phase 3 Study of Single-agent Tarceva (erlotinib) Following
Complete Tumor Resection with or without Adjuvant Chemotherapy in
Patients with Stage IB-IIIA Non-small Cell Lung Carcinoma who have EGFRpositive Tumors.
 SWOG-CALGB 140503 A phase III randomized trial of lobectomy versus
sublobar resection for small (2 cm or less) peripheral non-small cell lung
cancer.
 ACOSOG Z4051: A Phase II Study of Neoadjuvant Therapy with Cisplatin,
Docetaxil, Panitumumab Plus Radiation Therapy Followed by Surgery in
Patients with Locally Advanced Adenocarcinoma of the Distal Esophagus.
 COAPT Mitral Clip
 Heartware Ventricular Assist Device for Destination Therapy
NOVEL trial: Ex-vivo lung perfusion for lung transplantation
 PERIGON Valve Multi-Institutional Trail
Cardiothoracic Surgery
Research Laboratory
The Division of Cardiothoracic Surgery
Research Laboratory is located in the
state-of-the-art Research Complex II
adjacent to our physician office building.
Dr. Fullerton is the Director of the
Cardiothoracic Surgical Research Lab
and Dr. Shin Meng oversees the
laboratories. Dr. Meng is independently funded investigator from the NIH. Both
are invaluable in the conduct of basic scientific research activities of the clinical
faculty.
Our laboratory is staffed at all times by professional research
associates, surgical residents and medical students.
Several lines of basic scientific investigation are currently ongoing in our
laboratory. Examples include:
1. The mechanisms of gastroduodenal reflux-induced histological changes
in esophageal morphology
2. The pathogenesis of calcific aortic stenosis
3. The role of Toll-like receptors in myocardial ischemia/reperfusion
4. The mechanisms of macrophage differentiation into foam cells and
dendritic cells
5. Mechanisms of spinal cord dysfunction following ischemia/reperfusion
6. Age-related changes in myocardial function
7. Genetic markers of aortopathology
8. The role of sPLA2 in lung and esophageal cancer
The Division has numerous research grants, thus offering a unique opportunity
for both general and thoracic residents to perform and be exposed to research.
An important strength of this laboratory arises from the synergy of combining
research training with surgical research. Surgical research trainees not only are
recognized as important resources in the design and conduct of the research,
but also add fresh viewpoints to the research projects. Thoracic surgery
residents are invited to participate in basic and clinical research activities of the
Division.
CT Faculty Publications 2011-2014
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
Karamichalis JM, Miyamoto SD, Campbell DN, Smith J, McFann KK, Clark S,
Pietra B, and Mitchell MB. Pediatric Cardiac Retransplant: Differing Patterns of
Primary Graft Failure by age At First Transplant. J Thorac Cardiovasc Surg
2011;141:223-30
Sadaria MR, Meng X, Fullerton DA, Reece TB, Shah RR, Grover FL, Weyant
MJ: Secretory hospholipase A(2) inhibition attenuates intracellular adhesion
molecule-1 expression in human adenocarcinoma cells. Ann Thorac Surg May
2011, 91:1539-45.
Bakaeen FG, Stephens EH, Chu D, Holman WL, Vaporciyan AA, Merrill WH,
Grover FL: Perceptions regarding cardiothoracic surgical training at Veterans
Affairs hospitals. J Thorac Cardiovasc Surg May 2011, 141(5):1107-13.
Grover FL, Edwards FH: Objective Assessment of Cardiac Risk for Noncardiac
Surgical Patients:An Up-to-Date Simplified Approach. Circ July 26 2011,
124:376-377.
Jacobs JP, Edwards FH, Shahian DM, Prager RL, Wright CD, Puskas JD,
Morales DL, Gammie JS, Sanchez JA, Haan CK, Badhwar V, George KM,
O’Brien SM, Dokholyan RS, Sheng S. Peterson ED, Shewan CM, Feehan KM,
Han JM, Jacobs ML, Williams WG, Mayer JE Jr, Chitwood WR Jr, Murray GF,
Grover FL: Successful linking of the Society of Thoracic Surgeons database to
social security data to examine survival after cardiac operations. Ann Thorac
Surg 2011 Jul, 92(1):32-7; discussion 38-9.
Sadaria MR, Smith PD, Fullerton DA, Justison GA, Lee JH, Puskas F, Grover
FL, Cleveland JC Jr, Reece TB, Weyant MJ: Cytokine expression profile in
human lungs undergoing normothermic ex-vivo lung perfusion. Ann Thorac
Surg 2011 Aug, 92(2):478-84.
Shahian DM, Edwards FH, Jacobs JP, Prager RL, Normand SL, Shewan CM,
O’Brien SM, Peterson ED, Grover FL: Public reporting of cardiac surgery
performance: Part 1—history, rationale, consequences. Ann Thorac Surg 2011
Sep, 92(3Suppl):S2-11.
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104. Carroll JD, Edwards FH, Marinac-Dabic D, Brindis RG, Grover FL,
Peterson ED, Tuzcu EM, Shahian DM, Rumsfeld JS, Shewan CM, Hewitt
K, Holmes DR Jr, Mack MJ: The STS-ACC Transcatheter Valve Therapy
National Registry: a New Partnership and Infrastructure for the Introduction
and Surveillance of Medical Devices and Therapies. J Am Coll Cardiol
2013 Sep 10, 62(11): 1026-34.
105. Grover FL, Mack MJ: The Current Role of Artery Bypass in Diabetics with
Multivessel Coronary Disease. Eurointervention 2013 Jun 22, 9(2): 183-6.
106. Rich J, Grover FL, Prager RL, Speir A: Quality Improvement in Cardiac
Surgery: January 30, 2014, Los Angeles, CA. Semin Thorac Cardiovasc
Surg 2013 Summer; 25 (2): 171-91.
107. Quin JA, Hattler B, Bishawi M, Baltz J, Gupta S, Collins JF, Grover FL,
McDonald G, Shroyer AL: Impact of Lipid-Lowering Medications and LowDensity Lipoprotein Levels on 1-Year Clinical Outcomes After Coronary
Bypass Grafting. J Am Coll Surg 2013 Sep, 217(#): 452-60.
108. Wagner TH, Hattler B, Bishawi M, Baltz JH, Collins JF, Quin JA, Grover
FL, Shroyer AL: VA #517 Randomized On/Off Bypass (ROOBY) Study
Group. On-Pump Versus Off-Pump Coronary Artery Bypass Surgery:
Cost-Effectiveness Analysis Alongside a Multisite Trial. Ann Thoracic Surg
2013 Sep, 96(3): 770-7.
109. Almassi GH, Shroyer AL, Collins JF, Hattler B, Bishawi M, Baltz JH,
Ebrahimi R, Grover FL: Chronic Obstructive Pulmonary Disease Impact
Upon Outcomes; the Veterans Affairs Randomized On/Off Bypass Trial.
Ann Thorac Surg 2013 Oct, 96(4): 1302-9.
110. Mack MJ, Brennen JM, Brindis R, Carroll J, Edwards F, Grover F, Shahian
D, Tuzcu EM, Peterson ED, Rumsfeld JS, Hewitt K, Shewan C, Michaels
J, Christensen B, Christian A, O’Brien S, Holmes D: Outcomes Following
Transcatheter Aortic Valve Replacement in the United States. JAMA 2013
Nov 20, 310(19):2069-77.
111. Wagner TH, Shroyer AL, Hattler B, Collins JF, Grover FL: VA #517
Randomized On/Off Bypass (ROOBY) Study Group: The Challenges of
Interpreting Cost-Effective Data. Scand Cardiovasc J 2013 Dec, 47(6):
383.
112. Hauck A, da Cruz EM, Jaggers J, Jone PN. Tricuspid atresia associated
with truncus arteriosus versus aortopulmonary window: combining fetal
and postnatal echocardiography to make the diagnosis. Echocardiography.
2013 Nov;30(10):E336-9.
113. Wood DE, Mitchell JD, Schmitz DS, Grondin SC, Ikonomidis JS, Bakaeen
FG, Merritt RE, Meyer DM, Moffatt-Bruce SD, Reece TB, Smith MA:
Choosing wisely: cardiothoracic surgeons partnering with patients to make
good health care decisions. Ann Thorac Surg. 2013;95(3):1130-5.
114. Mitchell JD, Krasna MJ: The Society of Thoracic Surgeons esophageal
cancer guideline series. Ann Thorac Surg 2013;96(1):7
115. Varghese TK Jr, Hofstetter WL, Rizk NP, Low DE, Darling GE, Watson TJ,
Mitchell JD, Krasna MJ: The Society of Thoracic Surgeons guidelines on
the diagnosis and staging of patients with esophageal cancer. Ann Thorac
Surg. 2013;96(1):346-56.
116. Mitchell JD: Invited commentary. Ann Thorac Surg. 2013;96(1):292.
117. Rocco G, Allen MS, Altorki NK, Asamura H, Blum MG, Detterbeck FC,
Dresler CM, Gossot D, Grondin SC, Jaklitsch MT, Mitchell JD, Newton JR,
118.
119.
120.
121.
122.
123.
124.
125.
126.
127.
128.
129.
130.
Van Schil PE, Waddell TK, Wood DE: Clinical statement on the role of the
surgeon and surgical issues relating to computed tomography screening
programs for lung cancer. Ann Thorac Surg 2013;96(1):357-60.
Mitchell JD: Techniques of VATS lobectomy. J Thorac Dis 2013;5(Suppl
3):S177-81.
Mitchell JD: Invited commentary. Ann Thorac Surg 2013;96(5):1802-3.
Almond C, Morales D, Blackstone E, Turrentine M, Michiaki I, Massicotte
MP, Jordan L, Devaney E, Ravishankar C, Kanter K, Holman W,
Kroslowitz R, Tjossem C, Thuita L, Cohen G, Buchholz H, St. Louis J,
Nguyen K, Niebler R, Walters H, Reemsten B, Wearden P, Reinhartz O,
Guleserian K, Mitchell MB, Bleiweis M, Canter C, Tilman H. The Berlin
Heart EXCOR® pediatric ventricular assist device for bridge to heart
transplantation among children in the United States. Circulation 2013;127
(16):1702-11
Mitchell MB, Goldberg S. Left Ventricular Outflow Tract - Supravalvar
aortic stenosis. Operative Techniques in Thoracic and Cardiovascular
Surgery: A comparative Atlas. 2011; 16:70-84
Kaza AK, Mitchell MB. Transplantation and Organ Procurement. Trauma,
7th Edition. Moore EE, Feliciano DV, Mattox KL, eds. McGraw-Hill, 2013
pp.944-49
Karamichalis JM, Darst JR, Mitchell MB, Clarke DR. Isolated right
ventricular outflow tract obstruction. Pediatric Cardiac Surgery, 4th Edition.
Mavroudis C, Backer CL, eds. John Wiley and Sons, Inc. 2013 pp. 385409
Jelacic, S., Meguid, R.A., Oxorn, D.C.: Echo Rounds: Near total occlusion
of the main pulmonary artery and destruction of pulmonary valve by
leiomyosarcoma. Anesth Analg 2013 (Jan); 116(1):53.
Meguid, R.A. Van Arendonk, K.J., and Lipsett, P.A.: The Johns Hopkins
A.B.S.I.T.E. Review Manual, Second Edition. Philadelphia: Lippincott,
Williams and Wilkins, 2013. ISBN 978-0-7817-9178-6.
Hayanga, A.J., Montanaro, N.F, Meguid, R.A.: Antibiotics, in General
Surgery Review. 3rd Edition. Ed: Makary, M.A., Cooper, M., Philadelphia:
Lippincott, Williams and Wilkins, 2013. 603-618.
Algrhen, B, Salcedo EE, Reece TB, Seres T: Constrictive Pericarditis with
a Calcific Mass Invading into the Right Ventricular Myocardium,
Echocardiography Jan 2013, 30(1):E4-6.
Ahlgren B, Dorosz J, Rohrer A, Reece TB, Cleveland J, Salcedo E, Seres
T: Real time three-dimensional transesophageal echocardiography in the
evaluation of two cases of rare mitral valve tumors. Echocardiography
Sep 2012, 29(8):1011-5.
Smith PD, Bell MT, Puskas F, Meng X, Cleveland JC, Weyant MJ,
Fullerton DA, Reece TB: Preservation of Motor Function Following Spinal
Cord Ischemia and Reperfusion Through Microglial Inhibition. Ann Thorac
Surg May 2013, 95(5):1647-53.
Svensson LG, Adams DH, Bonow RO, Kouchoukos NT, Miller DC, O'Gara
PT, Shahian DM, Schaff HV, Akins CW, Bavaria J, Blackstone EH, David
TE, Desai ND, Dewey T, D'Agostino RS, Gleason T, Harrington KB, Kodali
S, Kapadia S, Leon M, Lima B, Lytle BW, Mack MJ, Reece TB, Reiss GR,
Roselli E, Smith CR, Thourani VH, Tuzcu EM, Webb J, Williams MR: The
Society of Thoracic Surgeons' Guidelines for Management and Quality
131.
132.
133.
134.
135.
136.
137.
138.
139.
140.
141.
Measures for the Aortic Valve and Ascending Aorta: Executive Summary.
Ann Thorac Surg Jan 2013, 95(4):1491-505.
Wood DE, Mitchell JD, Schmitz DS, Grondin SC, Ikonomidis JS, Bakaeen
FG, Merritt RE, Meyer DM, Moffatt-Bruce SD, Reece TB, Smith MA:
Choosing Wisely: Cardiothoracic Surgeons Partnering With Patients to
Make Good Health Care Decisions. Ann Thorac Surg Mar 2013, 95
(3):1130-5.
Sadaria MR, Yu JA, Meng X, Fullerton DA, Reece TB, Weyant MJ:
Secretory Phospholipase A2 Mediates Human Esophageal
Adenocarcinoma Cell Growth and Proliferation via ERK ½ Pathway.
Anticancer Res Apr 2013, 33(4):1337-42.
Svensson LG, Adams DH, Bonow RO, Kouchoukos NT, Miller DC, O'Gara
PT, Shahian DM, Schaff HV, Akins CW, Bavaria J, Blackstone EH, David
TE, Desai ND, Dewey T, D'Agostino RS, Gleason T, Harrington KB, Kodali
S, Kapadia S, Leon M, Lima B, Lytle BW, Mack MJ, Reece TB, Reiss GR,
Roselli E, Smith CR, Thourani VH, Tuzcu EM, Webb J, Williams MR: Aortic
Valve and Ascending Aorta Guidelines for Management and Quality
Measures. Ann Thorac Surg Jun 2013, 95(6 supplement): S1-66.
Nadlonek N, Lee JH, Reece TB, Weyant MJ, Cleveland JC Jr, Meng X,
Fullerton DA: Interleukin-1 Beta Induces an Inflammatory Phenotype in
Human Aortic Valve Interstitial Cells Through Nuclear Factor Kappa Beta.
Ann Thorac Surg Jul 2013, 96(1):155-62.
Stevens Q, Ahlgren B, Weitzel N, Reece TB, Puskas F: Intraoperative
Transesophageal Echocardiography to Diagnose an Anomalous
Circumflex Artery. J Card Surg Jul 2013, 28(4):399-401.
Bell MT, Agoston VA, Freeman KA, Puskas F, Herson PS, Mares J,
Fullerton DA, Reece TB: Interruption of spinal cord microglial signaling by
alpha-2 agonist dexmedetomidine in a murine model of delayed
paraplegia. J Vasc Surg Apr 2014, 59)4):1090-7.
Bell MT, Puskas F, Bennett DT, Herson PS, Quillinan N, Fullerton DA,
Reece TB: Dexmedetomidine, an α-2a adrenergic agonist, promotes
ischemic tolerance in a murine model of spinal cord ischemia-reperfusion.
J Thorac Cardiovasc Surg Jan 2014, 147(1):500-6
Bell MT, Puskas F, Agoston VA, Cleveland JC Jr, Freeman KA, Gamboni
F, Herson PS, Meng X, Smith PD, Weyant MJ, Fullerton DA, Reece TB:
Toll-like receptor 4-dependent microglial activation mediates spinal cord
ischemia-reperfusion injury. Circulation Sep 2013, 128(26 Suppl 1):S1526.
Pagani FD, Acker MA, Camacho MT, Dewey TM, Force SD, McGee EC
McGrath MF, Meyers BF, Mokadam NA, Smedira NG, Toyoda Y, Wallace
AF, Weyant MJ: Clinical statement on the requirements for surgeon
certification for implantation of durable Ventricular Assist Devices (VADs).
Ann Thorac Surg 2013;95(5):1834-9.
Smith PD, Bell MT, Puskas F, Meng X, Cleveland JC Jr, Weyant MJ,
Fullerton DA, Reece TB: Preservation of motor function after spinal cord
ischemia and reperfusion injury through microglial inhibition. Ann Thorac
Surg 2013;95(5):1647-53.
Stafford M, Cappa A, Weyant M, Lara A, Ellis J Jr, Weitzel NS, Puskas F:
Treatment of acute silicoproteinosis by whole-lung lavage. Semin
Cardiothorac Vasc Anesth 2013; 17(2):152-9.
142. Zeng Q, Song R, Ao L, Weyant MJ, Lee J, Xu D, Fullerton DA, Meng X:
Notch1 Promotes the Pro-Osteogenic Response of Human Aortic Valve
Interstitial Cells via Modulation of ERK1/2 and Nuclear Factor-κB
Activation. Arterioscler Thromb Vasc Biol 2013;33(7):1580-90.
143. Nadlonek NA, Lee JH, Weyant MJ, Meng X, Fullerton DA: ox-LDL induces
PiT-1 expression in human aortic valve interstitial cells. J Surg Res
2013;184(1):6-9.
144. Robinson TN, Wu DS, Pointer L, Dunn CL, Cleveland JC Jr, Moss M.
Simple frailty score predicts postoperative complications across surgical
specialties. Am J Surg 2013 Oct; 206(4):544-50.
145. Robinson TN, Wu DS, Sauaia A, Dunn CL, Stevens-Lapsley JE, Moss M,
Stiegmann GV, Gajdos C, Cleveland JC Jr, Inouye SK. Slower walking
speed forecasts increased post-operative morbidity and mortality and 1year mortality across surgical specialties. Ann Surg 2013 Oct;258(4):58290.
146. Cleveland JC Jr. A perfect storm: type A aortic dissection and previous
cardiac surgery. Circulation 2013 Oct 8;128(15):1593-94.
147. Jones TS, Dunn CL, Wu DS, Cleveland JC Jr, Kile D, Robinson TN.
Relationship between asking an older adult about falls and surgical
outcomes. JAMA Surg 2013 Dec; 148(12):1132-8.
148. Ward S, Hicks G, Calhoon J, Verrier ED, Shemin R, Smith D, Fullerton DA,
Lee R: A comparison of cardiothoracic training curricula; integrated six
year vs traditional programs. Ann Thorac Surg 2013;95:2051-2056.
149. Walker L, Fullerton DA, Buttrick P: Contractile Protein Phosphorylation
Predicts Human Heart Disease Phenotypes. Am J Physiol-Heart and Circ
Phys 2013;304:H1644-1650.
150. Piccini JP, Zhao Y, Steinberg BA, He X, Mathew JP, Fullerton DA,
Hegland DD, Hernandez AF, Mills RM, Klaskala W, Peterson ED.
Comparative Effectiveness of Pharmacotherapies for Prevention of Atrial
Fibrillation Following Coronary Artery Bypass Surgery. Am Coll Cardiol
2013; 112:954-960.
151. Scott R. Auerbach, Jane Gralla, David N Campbell, Shelley Miyamoto, and
Biagio A. Pietra. Steroid Avoidance in Pediatric Heart Transplantation
Results in Excellent Graft Survival. Transplantation 2014;97(4):474-80
152. Ellis WC, Butler K, Campbell, D, Barrett C, and Buckvold, S. One-Way
valve Malfunction in an Extracorporeal Membrane Oxygenation Priming
Circuit. JECT. 2014;46:98-100.
153. Gien J, Ing RJ, Twite MD, Campbell, D, Mitchell, M, and Kinsella JP.
Successful Surgical Management Of Airway Perforation in Preterm Infants.
Journal of Pediatric Surgery Case Reports. Feb, 2014; 2(2):47-51.
154. Gist KM, Schuchardt EL, Moroze MK, Kaufman J, da Cruz E, Campbell DN
et al. Tachyarrhythmia Following Norwood Operation: A Single-Center
Experience. World Journal for Pediatric and Congenital Heart Surgery.
2014, Vol.5(2) ;206-210.
155. Reece TB, Welke KF, O'Brien S, Grau-Sepulveda MV, Grover FL, Gammie
JS: Rethinking the Ross Procedure in Adults. Ann Thorac Surg 2014 Jan,
97(1): 175-81.
156. Ebrahimi R, Bakaeen FG, Uberoi A, Ardehali A, Baltz JH, Hattler B,
Almassi GH, Wagner TH, Collins JF, Grover FL, Shroyer AL: Effect of
157.
158.
159.
160.
161.
162.
163.
164.
165.
166.
167.
Clopidogrel Use Post Coronary Artery Bypass Surgery on Graft Patency.
Ann Thorac Surg 2014 Jan, 97(1):15-21.
Grover FL, Shahian DM, Clark RE, Edwards FH: The STS National
Database. Ann Thorac Surg 2014 Jan, 97(1 Suppl): S48-54.
Shapira OM, Badhwar V, Shahian D, Jacobs JP, Izhar U, Bao Y, Korach
A, Lattouf OM, Grover FL, Puskas JD: International Participation in the
Society of Thoracic Surgeons National Database. Ann Thorac Surg 2014
April, 97(4): 1127-30.
Almassi GH, Shroyer AL, Collins JF, Grover FL: ROOBY Trial Data
Demonstrates Revascularization Had No Impact on POAF. Future Cardiol
2014 March, 10(2): 157.
Edwards FH, Shahian DM, Grau-Sepulveda MV, Grover FL, Mayer JE,
O'Brien SM, DeLong E,
Peterson ED, McKay C, Shaw RE, Garratt KN, Dangas GD, Messenger J,
Klein LW, Popma JJ,
Weintraub WS: Composite Outcomes in Coronary Bypass Surgery Versus
Percutaneous Intervention. Ann Thorac Surg 2014 Jun, 97(6): 1983-8.
Shroyer AL, Hattler B, Wagner TH, Baltz JH, Collins JF, Carr BM, Almassi
GH, Quin JA, Hawkins RB, Kozora E, Bishawi M, Ebrahimi R, Grover FL;
VA #517 Randomized On/Off Bypass (ROOBY) Study Group: Comparing
Off-Pump and On-Pump Clinical Outcomes and Costs for Diabetic Cardiac
Surgery patients. Ann Thorac Surg 2014 Jul, 98(1): 38-45.
Shahian DM, He X, O'Brien S, Grover FL, Jacobs JP, Edwards FH, Welke
KF, Suter LG, Drye E,
Shewan CM, Han L, Peterson ED: Development of a Clinical RegistryBased 30-Day Readmission Measure for Coronary Artery Bypass Grafting
Surgery. Circulation 2014 June 10.
Shroyer AL, Hattler B, Wagner TH, Baltz JH, Collins JF, Carr BM, Almassi
GH, Quin JA, Hawkins RB, Kozora E, Bishawi M, Ebrahimi R, Grover FL:
VA #517 Randomized On/Off Bypass (ROOBY) Study Group. Comparing
off-pump and on-pump clinical outcomes and costs for diabetic cardiac
surgery patients. Ann Thorac Surg 2014 Jul, 98(1):38-44.
Shahian DM, He X, O'Brien SM, Grover FL, Jacobs JP, Edwards FH,
Welke KF, Suter LG, Drye E, Shewan CM, Han L, Peterson E:
Development of a clinical registry-based 30-day readmission measure for
coronary artery bypass grafting surgery. Circulation 2014 Jul 29, 130
(5):399-409.
Bakaeen FG, Shroyer AL, Gammie JS, Sabik JF, Cornwell LD, Coselli JS,
Rosengart TK, O'Brien SM, Wallace A, Shahian DM, Grover FL, Puskas
JD: Trends in use of off-pump coronary artery bypass grafting: Results
from the Society of Thoracic Surgeons Adult Cardiac Surgery Database. J
Thorac Cardiovasc Surg 2014 Sep, 148(3): 856-3, 864.
Shahian DM, Grover FL: Biomarkers and risk models in cardiac surgery.
Circulation 2014 Sep 16, 130(12):932-5.
Quin J, Lucke J, Hattler B, Gupta S, Baltz J, Bishawi M, Almassi GH,
Grover FL, Collins J, Shroyer AL: Surgeon judgment and utility of transit
time flow probes in coronary artery bypass grafting surgery. JAMA Surg
2014 Nov 1, 149(11):1182-7.
168. Jacobs JP, O'Brien SM, Pasquali SK, Kim S, Gaynor JW, Tchervenkov CI,
Karamlou T, Welke KF, Lacour-Gayet F, Mavroudis C, Mayer JE Jr, Jonas RA,
Edwards FH, Grover FL, Shahian DM, Jacobs ML: The importance of patientspecific preoperative factors: an analysis of the society of thoracic surgeons
congenital heart surgery database. Ann Thorac Surg 2014 Nov, 98(5):1653-9.
169. Deng XS, Meng X, Zeng Q, Fullerton D, Mitchell M, Jaggers J. Adult Aortic
Valve Interstitial Cells Have Greater Responses to Toll-Like Receptor 4
Stimulation. Ann Thorac Surg. 2014 Oct 22. pii: S0003-4975(14)01578-1.
170. Goot BH, Jaggers J, Anagnost MR, Collins KK. Multivalvular Replacement and
Ventricular Arrhythmias in a Female Child With Congenital Polyvalvular
Disease. World J Pediatr Congenit Heart Surg. 2014 Jun 23;5(3):463-466.
171. McFerson MC, McCanta AC, Pan Z, Collins KK, Jaggers J, da Cruz EM,
Kaufman J. Tachyarrhythmias after the Norwood procedure: relationship and
effect of vasoactive agents. Pediatr Cardiol. 2014 Apr;35(4):668-75.
172. Boffa DJ, Dhamija A, Kosinski AS, Kim AW, Detterbeck FC, Mitchell JD, Onaitis
MW, Paul S: Fewer complications result from a video-assisted approach to
anatomic resection of clinical stage I lung cancer. J Thorac Cardiovasc Surg
2014;148(2):637-43.
173. Ferguson MK, Saha-Chaudhuri P, Mitchell JD, Varela G, Brunelli A: Prediction
of major cardiovascular events after lung resection using a modified scoring
system. Ann Thorac Surg 2014;97(4):1135-40.
174. Bennett DT, Reece TB, Smith PD, Grandhi MS, Rove JA, Justison GA, Mitchell
JD, Fullerton DA, Zamora MR, Weyant MJ: Ex vivo lung perfusion allows
successful transplantation of donor lungs from hanging victims. Ann Thorac
Surg 2014;98(3):1051-6.
175. Little AG, Lerut AE, Harpole DH, Hofstetter WL, Mitchell JD, Altorki NK, Krasna
MJ: The Society of Thoracic Surgeons practice guidelines on the role of
multimodality treatment for cancer of the esophagus and gastroesophageal
junction. Ann Thorac Surg 2014;98(5):1880-5.
176. Hawkins SMM, Taylor AL, Sillau SH, Mitchell MB, Rausch C. Restrictive lung
function in pediatric patients with structural congenital heart disease. J Thorac
Cardiovasc Surg 2014; 148:207-11 (PMID 24060364)
177. Simios AK, Mitchell MB, Fonseca BM. Successful surgical repair of a massive
window duct in a 1-month old with anirirdia and interstitial glycogenosis. Cardiol
Young 2014 May 22:1-3.
178. Moore, H.B., Juarez-Colunga, E., Bronsert, M., Hammermeister, K.E.,
Henderson, W.G., Moore, E.E., Meguid, R.A.: Are Pregnant Patients
Undergoing General Surgery Subject to Increased Morbidity and Mortality?
Accepted for publication by JAMA Surgery on December 2, 2014.
179. Meguid, R.A., Brock, M.V.: Chest Wall Tumors, in Johns Hopkins Textbook of
Cardiothoracic Surgery, 2nd Edition. Ed: Yuh, D.D., Vricella, L.A., Yang, S.,
Doty, J.R., New York: McGraw Hill, 2014. 243-266.
180. Bennett, D.T., Meguid, R.A., Mitchell, J.D., Weyant, M.J.: Pleural Space and
Mediastinum, in DHMC Handbook of Surgical Critical Care: The Practice and
the Evidence. Ed: Pieracci, F.M., Singapore: World Scientific Publishing, 2014.
181. Reece TB, Cleveland JC Jr: Noteworthy Cardiac Surgical Literature in 2013.
Semin Cardiothorac Vasc Anesth Mar 2014, 18)1):12-6.
182. Venardos N, Nadlonek NA, Zhan Q, Weyant MJ, Reece TB, Meng X, Fullerton
DA: Aortic valve calcification is mediated by a differential response of aortic
valve interstitial cells to inflammation. J Surg Res Jul 2014, 190(1):108.
183. Bennett DT, Deng XS, Yu JA, Bell MT, Mauchley DC, Meng X, Reece TB,
Fullerton DA,Weyant MJ: Cancer stem cell phenotype is supported by
secretory phospholipase A2 in human lung cancer cells. Ann Thorac Surg Aug
2014, 98(2): 439-45; discussion 445-6.
184. Bell MT, Reece TB, Smith PD, Mares J, Weyant MJ, Cleveland JC Jr,
Freeman KA, Fullerton DA, Puskas F: Reproducable paraplegia by thoracic
aortic occlusion in a murine model of spinal cord ischemia-reperfusion. J Vis
Exp 2014;(85).
185. Bennett DT, Weyant MJ: The year in thoracic surgery: Highlights from 2013.
Semin Cardiothorac Vasc Anesth 2014;18(1):24-8.
186. Alegre MM, Weyant MJ, Bennett DT, Yu JA, Ramsden MK, Elnaggar A,
Robison RA, O’Neill KL: Serum detection of thymidine kinase 1 as a means of
early detection of lung cancer. Anticancer Res 2014;34(5):2145-51.
187. Browning ET, Huckleberry JM, Barrow WB, Restauri NL, Kemme DJ, Cool CD,
Weyant MJ, Franklin WA, Camidge DR: Downstaging of Non-Small-Cell Lung
Cancer Through Identification of Reversible Drug Toxicity. J Clin Oncol 2014.
188. Bennett DT, Weyant MJ: Extended Chest Wall Resection and Reconstruction
in the Setting of Lung Cancer. Thorac Surg Clin 2014;24(4):383-390.
189. Freeman KA, Fullerton DA, Foley LS, Bell MT, Cleveland JC Jr, Weyant MJ,
Mares J, Meng X, Puskas F, Reece TB: Spinal cord protection via alpha-2
agonist-mediated increase in glial cell-line-derived neurotrophic factor. J
Thorac Cardiovasc Surg 2014.
190. January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr,
Conti, JB, Ellinor PT, Ezekowitz MD, Field ME, Murray KT, Sacco RL,
Stevenson WG, Tchou PJ, Tracy CM, Yancy CW. 2014 AHA/ACC/HRS
Guideline for the Management of Patients With Atrial Fibrillation: A Report of
the American College of Cardiology/American Heart Association Task Force
on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014
Dec 2;64(21):e1-e76.
191. January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr,
Conti JB, Ellinor PT, Ezekowitz MD, Field ME, Murray KT, Sacco RL,
Stevenson WG, Tchou PJ, Tracy CM, Yancy CW. 2014 AHA/ACC/HRS
Guideline for the Management of Patients With Atrial Fibrillation: Executive
Summary: A Report of the American College of Cardiology/American Heart
Association Task Force on Practice Guidelines and the Heart Rhythm Society.
J Am Coll Cardiol. 2014 Dec 2;64(21):2246-80.
192. January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr,
Conti JB, Ellinor PT, Ezekowitz MD, Field ME, Murray KT, Sacco RL,
Stevenson WG, Tchou PJ, Tracy CM, Yancy CW. 2014 AHA/ACC/HRS
Guideline for the Management of Patients With Atrial Fibrillation: Executive
Summary: A Report of the American College of Cardiology/American Heart
Association Task Force on Practice Guidelines and theHeart Rhythm Society.
Circulation. 2014 Dec 2;130(23):2071-104.
193. January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr,
Conti JB, Ellinor PT, Ezekowitz MD, Field ME, Murray KT, Sacco RL,
Stevenson WG, Tchou PJ, Tracy CM, Yancy CW. 2014 AHA/ACC/HRS
Guideline for the Management of Patients With Atrial Fibrillation: A Report of
the American College of Cardiology/American Heart Association Task Force
on Practice Guidelines and the Heart Rhythm Society. Circulation. 2014 Dec
2;130(23):e199-267.
194. Bell MT, Reece TB, Smith PD, Mares J, Weyant MJ, Cleveland JC Jr, Freeman
KA,
Fullerton DA, Puskas F. Reproducible paraplegia by thoracic aortic occlusion in a
murine model of spinal cord ischemia-reperfusion. J Vis Exp. 2014 Mar 3;(85).
195. Hafermann MJ, Kiser TH, Lyda C, Fish DN, Barber GR, Wempe MF, Cleveland JC
Jr. Weight-based versus set dosing of vancomycin for coronary artery bypass
grafting or aortic valve surgery. J Thorac Cardiovasc Surg. 2014 Jun;147(6):192530.
196. Cleveland JC Jr. Invited commentary. Ann Thorac Surg. 2014 Feb;97(2):616.
197. Nallamothu BK, Tommaso CL, Anderson HV, Anderson JL, Cleveland JC Jr,
Dudley RA, Duffy PL, Faxon DP, Gurm HS, Hamilton LA, Jensen NC, Josephson
RA, Malenka DJ, Maniu CV, McCabe KW, Mortimer JD, Patel MR, Persell SD,
Rumsfeld JS, Shunk KA, Smith SC Jr, Stanko SJ, Watts B. ACC/AHA/SCAI/AMAConvened PCPI/NCQA 2013 performance measures for adults undergoing
percutaneous coronary intervention: a report of the American College of
Cardiology/American Heart Association Task Force on Performance Measures,
the Society for Cardiovascular Angiography and Interventions, the American
Medical Association-Convened Physician Consortium for Performance
Improvement, and the National Committee for Quality Assurance. J Am Coll
Cardiol. 2014 Feb 25;63(7):722-45.
198. Nallamothu BK, Tommaso CL, Anderson HV, Anderson JL, Cleveland JC Jr,
Dudley RA, Duffy PL, Faxon DP, Gurm HS, Hamilton LA, Jensen NC, Josephson
RA, Malenka DJ, Maniu CV, McCabe KW, Mortimer JD, Patel MR, Persell SD,
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199. Steinberg BA, Zhao Y, He X, Hernandez AF, Fullerton DA, Thomas KL, Klaskala
W, Peterson ED, Piccini JP: Management of postoperative atrial fibrillation and
subsequent outcomes in contemporary patients undergoing cardiac surgery:
insights from the Society of Thoracic Surgeons CAPS-Care Atrial Fibrillation
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200. Venardos N, Nadlonek N, Meng X, Fullerton DA: Differential Inflammatory
Responses Mediate Aortic Valve Calcification. J Surg Res 2014.
201. Slimani H, Yufeng Z, Yousif N, Ao L, Fullerton D, Dinarello C, Meng X:
P504Critical role IL-37 to ameliorate endotoxemic cardiac depression in aging
mice: a critical role of suppression cardiodepressant cytokines. Cardiovasc Res.
2014;103 Suppl 1:S92. doi: 10.1093/cvr/cvu091.177. Epub 2014 Jun 27.
202. Tommaso CL, Fullerton DA, Feldman T, Dean LS, Hijazi ZM, Horlick E, Weiner
BH, Zahn E, Cigarroa JE, Ruiz CE, Bavaria J, Mack MJ, Cameron DE, Bolman RM
3rd, Miller DC, Moon MR, Mukherjee D, Trento A, Aldea GS, Bacha EA: SCAI/
AATS/ACC/STS operator and institutional requirements for transcatheter valve
repair and replacement. Part II. Mitral valve. J Thorac Cardiovasc Surg.
2014;148:387-400.
203. Jin C, Cleveland JC, Ao L, Li J, Zeng Q, Fullerton DA, Meng X.: Human
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Song R, Ao L, Zhao KS, Zheng D, Venardos N, Fullerton DA, Meng X.: Soluble
biglycan induces the production of ICAM-1 and MCP-1 in human aortic valve
interstitial cells through TLR2/4 and the ERK1/2 pathway. Inflamm Res. 2014
Tommaso CL, Fullerton DA, Feldman T, Dean LS, Hijazi ZM, Horlick E, Weiner
BH, Zahn E, Cigarroa JE, Ruiz CE, Bavaria J, Mack MJ, Cameron DE, Bolman
RM 3rd, Miller DC, Moon MR, Mukherjee D, Trento A, Aldea GS, Bacha EA:
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valve repair and replacement. Part II. Mitral valve. Ann Thorac Surg 2014.
Tommaso CL, Fullerton DA, Feldman T, Dean LS, Hijazi ZM, Horlick E, Weiner
BH, Zahn E, Cigarroa JE, Ruiz CE, Bavaria J, Mack MJ, Cameron DE, Bolman
RM 3rd, Miller DC, Moon MR, Mukherjee D, Trento A, Aldea GS, Bacha EA:
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valve repair and replacement. Part II. Mitral valve. Catheter Cardiovasc Interv.
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Zeng Q, Song R, Ao L, Xu D, Venardos N, Fullerton DA, Meng X.: Augmented
osteogenic responses in human aortic valve cells exposed to oxLDL and TLR4
agonist: a mechanistic role of Notch1 and NF-κB interaction.: PLoS One. 2014
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Shemin RJ, Fullerton DA, Mayer JE Jr, Wright DC, Iknonmidis: Manpower: What
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Mares JM, Foley LS, Bell MT, Bennett DT, Freeman KA, Meng X, Weyant MJ,
Cleveland JC Jr, Fullerton DA, Puskas F, Reece TB: Erythropoietin activates the
phosphorylated cAMP (adenosine 3’5’ cyclic monophosphate) response elementbinding protein pathway and attenuates delayed paraplegia after ischemiareperfusion injury. J Thorac Cardiovasc Surg 2014 ( in press).
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Song R, Fullerton DA, Ao L, Zheng D, Zhao KS, Meng X: BMP-2 and TGF-B1
mediate biglycan-induced pro-osteogenic reprogramming in aortic valve
interstitial cells. J Mol Med 2014 ( in press).
Slimani H, Shai Y, Yousif NG, Ao L, Zeng Q, Fullerton DA, Meng X: Enhanced
monocyte chemoattractant protein-1 production in aging mice exaggerates
cardiac depression during endoxemia. Crit Care 2014 (in press).
Wang D, Zeng Q, Song R, Ao L, Fullerton DA, Meng X: Ligation of ICAM-1 on
human aortic valve interstitial cells induces the osteogenic response: A critical
role of the Notch 1-NF-kB pathway in BMP-2 expression. Biochem Biophus Acta
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Division of Cardiothoracic Surgery
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