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Transcript
Simulating the human respiratory
pump reduces cost & mortality
Department of
Information Technology
Conclusion: The model gives quantitative insights about the human respiratory
pump.
Background: Modern respirators damages the muscles responsible for our
breathing. Loss of structure and function
of these muscles leads to increased
medical costs and in some cases patient
death.
The simple mass-spring model is not
suitable for modeling the displacements of the diaphragm. A more advanced model is needed.
Björn Karlsson
[email protected]
Linus Nilsson
[email protected]
Aims: To elaborate a model of the
human respiratory pump applicable to mechanical ventilation.
Advisors
Elisabeth Larsson
Senior lecturer at the
department of Information
Technology
Nicola Cacciani
MD specialist at the
department of Neurosciences
Future work: The model needs to
be enhanced
to provide reliable
e
results for respiratory and
muscular research. Two major
improvements are:
Methods: The 3D geometries of
the ribcage and diaphragm is reconstructed from computed tomography scans.
The muscular part of the diaphragm is modeled using a
simple mass-spring model.
The diaphragm contracts
(moves down) to make room
for air to fill the lungs, and
relaxes (moves up) to help
push air out.
A more advanced mathematical
model for the diaphragm.
Human respiratory model with
lungs, diaphragm and ribcage.
A description of the pressure
changes in the thoracic and
abdominal compartments.
These displacements are
formulated as a system of
ODEs which are numerically
solved using a symplectic
Euler.
Simulated diaphragm during maximum exhale
and inhale
Computed tomography scans are stacked
together to form a volume. The volume later
becomes segmented to only include the parts of
interest.