Download Mucosal Mapping™ – an invention, a discovery and the

Mucosal Mapping™ – an invention, a discovery and the presence of health
Slime and snot. Something most living creatures have because they help get rid of disease and are
the first line of defence. Slime, or mucus. Five years ago even James Watson, discoverer of the
double helix, said we know almost nothing about the mucosal immune system. But now we know
much more. The award winning invention of Mucosal Mapping™ (3D investigations from 2D sections)
let Quantidoc test what slimy barriers do when challenged by for example diet, hydrogen peroxide
and parasites. Just as proof of principle, you understand, not to limit the applications.
The invention happened in 2010 because we wanted to measure the mucus cells in a meaningful way
to compare the effect of treatments. It is objective, quantitative and so statistically robust that, if
there is a difference in a cage full of many thousands of fish, we can find it, down to 7 square
microns. It has been tested in 4 countries (Norway, Canada, Spain and Japan) on 4 species of slimy
creatures (salmon, trout, seabass and amberjack) and on 3 tissues (skin, gills and guts). In over 15
commercial scale and lab trials. The IP was transferred to Quantidoc, a startup out of University of
Bergen, in 2013 for commercial exploitation. Mucosal Mapping won the Hordaland Inventor Prize in
2013. Our current clients include big fish farming companies, feed developers, other international
research institutions and developers of antiparasitic treatments as well as those trying to find good
ways to measure welfare.
The discovery is that the mucous cells as a group have a distinct behavior, changing size and density
in response to the challenges. The behavior is predictable and shows an immune response that can
be enhanced or dysregulated by the test treatment and we can use this objective, quantifiable
Mucosal Mapping™ to test for real differences using standard statistical tests. We can aim for
documenting health. This is a unique tool to show how well the mucosal slimy barriers are standing
up to environmental and other challenges. It is the best, sustainable way forward. Isn’t your health
worth it too?
Quantidoc AS, quantification and documentation of barrier health.
Contact:
Ole Jacob Myre - CEO at +47 97733749 or [email protected]
Karin Pittman – CSO at +4791736382 or [email protected]
www.quantidoc.com or https://bergento.no/project/quantidoc/