Download Ch. 14 - FLASHES BIOLOGY

Human Genetics: Webquest
Ch. 14
Name: ____________________________
Period: _____ COOK
Karyotyping Webquest
Site 1: Genetic Science Learning Center ( http://learn.genetics.utah.edu/ )
Go to "Chromosomes and Inheritance" --> "How Do Scientists Read Chromosomes"
1. What are the three key features used to read chromosomes?
____________________________
_____________________________
_____________________________
Got to Make a Karyotype - Try it yourself - Create your own karyotype - turning on hints is okay.
What did you find difficult about matching the chromosomes? _____________________________
2. Go to -Using Karyotypes to Predict Genetic Disorders
What is trisomy? ________________________________________________________________________________________
What is monosomy? _____________________________________________________________________________________
What is a terminal deletion? ______________________________________________________________________________
3. For each of the Disorders, describe the chromosome abnormality and the symptoms. (Type each into the search box at
learn.genetics)
a. Cri Du Chat
b. Turner Syndrome
c. Klinefelter Syndrome
d. Williams Syndrome
Site 2: www.biology.arizona.edu
Click on Karyotyping under human biology and read the Introduction page:
1. What causes a dark band on the chromosome? ______________________________________
_____________________________________________________________________________
2. What is a centromere? _______________________________________________________
Patient Histories: *Click on Patient Histories. You will be completing a karyotype for Patient A, B & C
Patient A ( Click on the link to "Complete Patient A's Karyotype" )
*Match the chromosome to its homolog. After all the matches are complete you'll analyze your patient.
3. What is patient A's history (summarize) ______________________________________________
Human Genetics: Webquest
4. How many total chromosomes are in your karyotype - count them _________
Ch. 14
5. The last set of chromosomes is the sex chromosomes, if you have two large chromosomes, your patient is XX (female),
one large and one small indicates and XY (male).
a. What sex chromosomes does your patient have ________
c. Which chromosome set has an extra + _______
b. What diagnosis would you give this patient (what disease)? ______________
Patient B - click on the link to go to Patient B and repeat the above process.
6. What is Patient B's history (summarize) _______________________________________________
7. How many total chromosomes are in your karyotype - count them _________
a. What sex chromosomes does your patient have ________ b. Which chromosome set has an extra + _______
8. Finish the notation for this patient's karyotype : 47 X _____
9. What is the diagnosis? __________________________________
Patient C - click on the link to go to Patient C and repeat the above process.
10. What is patient C's history (summarize)? _________________________________________
11. How many total chromosomes are in your karyotype - count them _________
a. What sex chromosomes does your patient have ________ b. Which chromosome set has an extra + _______
12. Write out the correct notation for this karyotype. ________
13. What is the diagnosis? _________________________________________
Mendelian Traits Review Problems:
1. The D gene controls pea plant height. The DD and dd genotypes confer tall and dwarf phenotypes, respectively.
What is the relationship between D and d?
a. They are two different plant chromosomes.
b. They are alleles of the same gene.
c. They are two different genes on the same chromosome.
d. They are two possible homozygous genotypes.
e. They are two possible heterozygous genotypes.
2. In Mendel's basic experiment, he began with true-breeding parental (P) plants. What did he see when he crossfertilized P plants that had different traits?
a. All F1 plants had the trait of one or the other P plant.
b. The F1 plants showed a combination of the two P traits, in a 3:1 ratio.
c. The F1 plants showed a combination of the two P traits in a 1:1 ratio.
d. The F1 plants had new traits that were a blend of P traits.
e. The F1 plants had an entirely new trait, not seen in either P plant.
A and a are dominant and recessive alleles, respectively, of the same gene. Answer the following questions.
3. Which genotype(s) would result in an individual with the dominant phenotype?
a. AA and aa
b. AA and Aa
c. Aa and aa
d. only AA
e. only Aa
4. Which genotype(s) would result in an individual with the recessive phenotype?
a. aa only
b. Aa only
c. Aa or aa
d. AA only
e. AA or aa
5. How many different types of gametes can be generated by an individual with genotype AaBB?
a. 1
b. 2
c. 3
d. 4
e. 8