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Unit 9 Quiz
1. What happens during interphase phase of the cell cycle?
I. Cytokinesis
II. Cell growth
III. DNA replication
IV. Mitosis
A. I and II
B. I and III
C. II and III
D. II and IV
2. What is the interval between mitosis and initiation of DNA replication called?
A. G1
B. S
C. G2
D. M
3. Why don’t cells grow during early embryonic cell cycles?
A. G phases are longer than in adult cell cycles.
B. G phases are shorter than in adult cell cycles.
C. There are no G phases during embryonic cell cycles.
D. DNA does not replicate during embryonic cell cycles.
4. What type of cells in adult animals cease to divide?
A. Fibroblasts
B. Keratinocytes
C. Liver cells
D. Nerve cells
5. Radioactive thymidine labels cells in which phase of the cell cycle?
A. G1
B. S
C. G2
D. M
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6. Cells that are metabolically active but do not proliferate unless called on to do so by
appropriate extracellular signals are in what phase of the cell cycle?
A. G1
B. S
C. G0
D. M
7. Fill in the blank. The cell cycle checkpoint at which the cell is prevented from
initiating mitosis until DNA replication is completed is called ________ __.
A. G1 restriction point
B. G2 restriction point
C. M checkpoint
D. S phase restriction point
8. Progression from G1 to S is regulated principally by which cyclin-dependent kinases?
I. cdk2
II. cdc28
III. cdk4
IV. cdk8
A. I and II
B. I and III
C. I and IV
D. II and IV
9. The Cip/Kip family of cdk inhibitors inhibit the cdk4/cyclin D complex to affect which
phase of the cell cycle?
A. G1
B. S
C. G2
D. M
10. The activity of Cdk's during cell cycle progression is regulated by at least four
molecular mechanisms. Which of the following is the FIRST mechanism of cdk
regulation?
A. Phosphorylation of a conserved Cdk threonine residue around position 160
B. Phosphorylation of tyrosine residues near the Cdk amino terminus
C. Binding of inhibitory proteins called Cdk inhibitors or CKIs
D. Association of Cdk's with their cyclin partners
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