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CHEMISTRY 273 : Organic Chemistry II
Course Syllabus and Schedule
Spring 2004 (CRN 33692)
Instructor. Dr. Harry Davis. Office is in Kokio 116, the phone is 734-9186 and messages may be left on the
answering machine. email is [email protected]
Kapi’olani Community College is an Equal Opportunity/Affirmative Action Institution. If you have a disability and
have not voluntarily disclosed the nature of your disability and the support you need, you are invited to contact the
Special Student Services Office, 734-9552 (V/TTY), Ilima 105, for assistance.
Office Hours. Please feel free to get help from me during office hours, by appointment, or anytime I am not in
lecture:
MWF
9:30 - 10:00 AM
MW
12:00 – 1:30 PM, and 4:30 – 5:00 PM
You may also see me during the following scheduled lab if I am not giving a lecture or a review
F
1:30 - 5:00 PM in Kokio 109
Class. MW
1:45 - 3:00 PM in Olapa 215
Electronic Communication. Please check your email often as I will be using a list serve for rapid communication
concerning the course; such as homework problems, answer keys, and exam dates.
The Purpose of Chemistry 273. Chemistry 273 is the second semester of a two-semester organic chemistry
course designed for the science majors which require a lot of chemistry. The laboratory course, 273L, is also
required by these same majors.
Prerequisites. Completion of Chemistry 272.
Course competencies. These are listed in the KCC general catalog.
Course Materials.
1) required text: "Organic Chemistry" by McMurry, 6th ed. The study guide is recommended.
2) a basic scientific calculator, less than $20.
3) periodic table from the bookstore, $0.25
Course Structure. The course is composed of four units. There will not be assigned homework problems.
Appropriate resource materials will be placed in the Health and Natural Sciences Learning Resource Center
(HNSLRC) located in Kokio 202. Some resource materials will also be available on a website which will be
announced. You will be given an exam on the material covered in each of the first three units as they are
completed. The final exam will cover the entire course with major emphasis on unit four.
Grading. How well one does on an exam is relative and I feel that doing poorly on one exam does not
necessarily reflect what you have learned. Therefore, your lowest exam score on the first three units will be
counted only half as much as the other exams. All exams must be taken in order to pass. The grading scale
will be based on the following:
90-100% A
/ 80-89 % B
/
70-79 % C
/
60-69 % D
/
0 -60 % F
March 19 is the last day for withdrawal from the course. After this date a W will be assigned only for a
certified medical reason or for a death in the immediate family. A form requesting the incomplete grade can
only be filed by students who are close to completing the course with a passing grade. Students who stop
attending without withdrawing will receive an F. This is Departmental policy and not within control of the
instructor.
Missing an exam can have serious consequences. Do not wait until after the exam is given to try to make
up an exam. If you know that you have a scheduling conflict you must make arrangements with the Instructor
prior to the exam. In the case of an unexpected illness or problem you or a representative must notify the
Instructor before the exam is given and be prepared to present a doctors note or similar evidence to provide a
valid excuse. You might not receive full credit for late work or a make up exam.
Student Responsibility. The job of the Instructor is to provide the best possible presentation of the material
that he can, and to provide the best learning environment that is possible. It is not the Instructor's job to make
the student study nor to accommodate the student by making the standards of the course lower so that they
can pass. It is the student's responsibility to put forth the effort required to learn the material and to become
competent with it. This means doing lots of problems and using good study habits. The Instructor will be
happy to help you obtain these goals. Do not waste time trying to lower the standards of the course because
these are in congruence with the UH system as well as with the American Chemistry Society and the
International Union of Pure and Applied Chemistry. The student should not burden the Instructor with
scheduling problems and special requirements. This detracts from the experience of all other students as well
as the Instructor. The student should:
1. preview the lecture material before coming to class
2. attend every class and take notes for later review
3. bring the text to class to follow the lecture
4. do problems from the text until you are competent - the first step to learning is to find out
what you
don't know
5. make a list of what you don't understand and bring it to class and/or office hours
6. realize that this is a skills building course and so will require a lot of study outside of class.
Study Groups. Participation in study groups is the best way to learn chemistry - to learn by helping each
other. Please get to know each other and form study groups. Students from study groups outperform others.
What is Chemistry ? Chemistry is the study of how matter and energy behave. It is also a scientific method
for observing the world and all of life. Knowledge of chemistry is used to make new discoveries about the
world (research) and to change some aspects of the world by the invention of new materials and methods
(technology). Chemistry is used by most other scientific disciplines making it a basic or universal science.
There are hundreds of different fields and subfields of chemistry with very specific journals dedicated to each.
Finally, chemistry is a practical science that can be applied in everyday life. For example, you use chemistry
when you clean your house and when you read the food labels in the grocery store.
What is Organic Chemistry ? Organic chemistry is the study of the chemical and physical properties of
organic compounds. Organic compounds are those which contain carbon and represent over 95% of known
compounds. Some organic chemists isolate new compounds from natural sources and determine the
structural formulas. These new compounds may have important pharmacological functions such as anticancer drugs. Others try to synthesize compounds which have known structures and which are difficult or
expensive to obtain from natural sources. Other organic chemists try to determine how organic compounds
react so that we can gain a greater ability to synthesize compounds that we may want in the future. Most of
the materials that you are touching at the moment are man-made organic compounds.
What is Biochemistry ? Biochemistry is the application of chemical principles to biology. Science has
progressed to the point that almost every type of biological research requires some aspect of chemistry and
you will find that biochemistry covers a very wide range of subjects. Biochemists are usually involved in what
is called basic research, for example in the search for the exact cause of cancer. Fewer biochemists are
involved in applied research, for example the testing of a particular drug in cancer patients for the remission of
cancer. Biochemists would be involved in the development of the drug rather than its clinical trials.
Biochemistry starts with the study of the chemical and biological properties of the molecules which make
up living organisms. It then progresses to how these properties function in the organism. Diseases and
malfunctions are then studied on the molecular level, that is, how the diseased molecules are different, why
they become different, and what can be done to prevent them from becoming different.
very TENTATIVE LECTURE SCHEDULE
for Chemistry 273
week 1
M
Jan 12
W
Jan 14
Structural Determination : NMR – chapter 13
Structural Determination : NMR – chapter 13
week 2
M
Jan 19
W
Jan 21
week 3
M
Jan 26
W
Jan 28
Holiday, Martin Luther King Day
Conjugated Dienes and Ultraviolet Spectroscopy – chapter 14
Benzene and Aromaticity - chapter 15
Chemistry of Benzene: Electrophilic Aromatic Substitution - chapter 16
Chemistry of Benzene: Electrophilic Aromatic Substitution - chapter 16
Alcohols and Phenols - chapter 17
week 4
M
Feb 2
W
Feb 4
Alcohols and Phenols - chapter 17
Ethers and Epoxides; Thiols and Sulfides - chapter 18
week 5
M
Feb 9
W
Feb 11
EXAM on unit 1
Aldehydes and Ketones: Nucleophilic Addition Rxs - chapter 19
week 6
M
Feb 16
W
Feb 18
Holiday, Presidents’ Day
Aldehydes and Ketones: Nucleophilic Addition Rxs - chapter 19
week 7
M
Feb 23
W
Feb 25
Carboxylic Acids and Nitriles- chapter 20
Carboxylic Acid Derivatives and Nucleophilic Acyl Substitution Rxs- chapter 21
Carboxylic Acid Derivatives and Nucleophilic Acyl Substitution Rxs- chapter 21
week 8
M
Mar 1
W
Mar 3
Carbonyl Alpha-Substitution Rxs - chapter 22
Carbonyl Alpha-Substitution Rxs - chapter 22
week 9
M
Mar 8
W
Mar 10
EXAM on unit 2
Carbonyl Condensation Rxs - chapter 23
week 10
M
Mar 15
W
Mar 17
Carbonyl Condensation Rxs - chapter 23
Amines - chapter 24
Last day to withdraw is March 19
week 11
Mar 22-26
Spring Recess
week 12
M
Mar 29
W
Mar 31
Amines - chapter 24
Biomolecules: Carbohydrates - chapter 25
week 13
M
Apr 5
W
Apr 7
Biomolecules: Carbohydrates - chapter 25
Biomolecules: Amino Acids, Peptides, and Proteins - chapter 26
week 14
M
Apr 12
W
Apr 14
EXAM on unit 3
Biomolecules: Amino Acids, Peptides, and Proteins - chapter 26
week 15
M
Apr 19
Biomolecules: Lipids - chapter 27
W
Apr 21
Biomolecules: Lipids - chapter 27
week 16
M
Apr 26
W
Apr 28
Biomolecules: Heterocycles and Nucleic Acids - chapter 28
The Organic Chemistry of Metabolic Pathways - chapter 29
week 17
M
May 3
W
May 5
Orbitals and Organic Chemistry: Pericyclic Rxs - chapter 30
Synthetic Polymers – chapter 31 - LAST DAY OF INSTRUCTION
week 18
M
May 10
FINAL EXAM 12:15 - 2:15 PM in classroom