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How is Cancer Related to the Cell Cycle? 1. Regarding the causes of cancer: Indicate the relationship between cancer and the cell cycle Describe how cancer spreads through the body. Define the term "carcinogen" and name several carcinogens. 2. Define the terms "proto-oncogene" and "tumor suppressor gene"; explain (in general terms) why mutations in each of these genes can lead to cancer. 3. Describe the major cause and symptoms of melanoma (see reading assignment). 4. Describe, in general terms, how "nano shells" might be used in a new treatment for cancer (see reading assignment).