Download Cell Cycle worksheet Dr

Pre-lab worksheet
_____________________ Dr. Sengupta Date _____________
Go to the following weblink and first watch the news alert videos. Then on the top panel click on
‘Cell Cycle animations’ and answer the following questions in complete sentences. The worksheet
must be typed.
http://science-education.nih.gov/supplements/nih1/Cancer/activities/activity2_videos.htm
1. How does a normal cell in your body become cancerous?
2. Are all tumors capable of spreading to other parts of the body? What is the term that
describes this phenomenon?
3. How do cells control cell cycle? What are these chemicals called that control the cell cycle?
How were these chemicals discovered? Name the scientists that were involved therein.
4. Is cell growth and division in normal tissues controlled by an internal clock?
5. Draw and label the cell cycle. What happens in each of the phases?
6. Can mutations cause cancer? What are these chemicals called that can cause cancer?
Discuss with examples.
7. Discuss how mutations in proto-oncogenes and tumor suppressor genes can lead to
uncontrolled cell growth and division. Include in your answer an example of a protooncogene and a tumor suppressor gene.
Now for questions 8-11 read the lab handout and answer them in complete sentences.
8. What are cancer biomarkers? How are they being used to detect cancer activity? How are
biomarkers identified?
9. Discuss how PSA levels in blood are used to diagnose prostate cancer.
10. What are the known causes of cervical cancer? Explain with examples.
11. What in your opinion will this experiment involve? Explain.
12. How will you know whether or not the sample tested positive? Does this relate to any other
lab that we have done in class? If so, how?