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Lecture 16 Heart Test Review Of the three layers of the heart wall, the layer that contains the cardiac muscle is the…? Myocardium What is PERICARDITIS? Inflamed outer layer of the heart. Pericarditis can be caused by damage to the blood vessels (from infection, wound, autoimmune disease, etc)--blood leaks into pericardial cavity Pericarditis can lead to pericardial friction rub, adhesions, additional excess fluid in the pericardial cavity, or cardiac tapenade (pressure from fluid in the pericardial cavity which causes improper heart beat). It does NOT cause myocardial infarction. What causes it? What can it lead to? A penetrating stab wound to the heart wall that causes blood to leak into the pericardial cavity, leading to an improper heart beat is what condition? What condition of the heart is caused by bacterial infection, and can damage the valves? CARDIAC TAPENADE NOTE: this is not the same as having arrhythmia, which is a problem with the SA or AV node. The irregular heartbeat of cardiac tapenade is from a different cause, and treatment is different. Endocarditis Pulmonary Semilunar Valves What structure closes to prevent blood from going from the pulmonary artery back into the right ventricle? Describe the blood flow into and out of the heart, listing all the structures. Deoxy blood sup/inf vena cava R atrium tricuspid valve R ventricle pulmonary semilunar valve pulmonary artery lungs pulmonary veins Left atrium mitral (bicuspid) valve Left ventricle aortic semilunar valve aorta rest of body. The pulmonary circulation Stenosis (blockage) of the mitral valve may cause blood to back up into where? What structure is located between the ventricles and the great arteries? If the beating heart makes a “lub-dub” sound, the “dub” sound is caused by what? The Semilunar valves Vibrations that result from blood hitting the semilunar valves after they slam shut. When the Left & Right Ventricles contract at the same time, what is that called? What are the atria doing during this time? When ventricles are relaxed, it’s called? What are the atria doing during this time? What valves close at the start of systole? What valves close at the end of systole? What are the ventricles doing during systole? SYSTOLE -Ventricles contract -Atria relax DIASTOLE: -Ventricles relax -Atria contract Start of Systole (ventricles start to contract): Closing of the large valves (tricuspid and mitral) End of Systole (ventricles are relaxing): Semilunar valves are closed (aortic and pulmonary) Note: Systole means that the ventricles are contracting. What is the most common heart valve disorder? Mitral valve prolapse Picture of heart depolarization Describe the path that an action potential takes during depolarization of the heart. What does the Bundle of His do to the electrical signal pathway? What is the name of the condition when there is a problem with the SA or AV node which causes an irregular heartbeat? SA node, AV node, bundle of His, bundle branches, Purkinje fibers. Slows it down to give the atria a chance to finish contracting. ARRHYTHMIA Treatment is medicines or a pacemaker. What is the treatment? What condition means a heart beat that is too fast? What condition means a heart beat that is too slow? Too fast: tachycardia Too slow: bradycardia What condition is when the ventricles are unable to pump blood efficiently due to rapid, random contraction of cardiac muscle fibers. The muscle doesn’t contract as a unit. VENTRICULAR FIBRILLATION What is the term for PAIN caused by deficient blood delivery to the heart wall? Angina What is ISCHEMIA? ISCHEMIA: Lack of blood/ oxygen What is the proper term for a heart attack? Does death occur within a few minutes of a heart attack in 50% of the cases? Myocardial infarction No, death takes about 2 hours in 50% of the cases. What are the purposes of the following medicines: t-PA Beta blockers Aspirin Nitroglycerine What is the difference between arteriosclerosis and atherosclerosis? t-PA (dissolves blood clots) Beta-blockers (slows heart rate) Aspirin (prevents blood clots) Nitroglycerine (dilates coronary arteries) Arteriosclerosis is hardening of the arteries, caused by a build-up of calcium deposits in the artery wall; artery cannot expand with blood surges. Tends to be hereditary. Atherosclerosis is caused by a build-up of fat in the arteries, from eating fatty foods -narrowing of artery - Spasm shut or blood clot. Both cause High Blood Pressure What is the difference between an embolism and a thrombis? A thrombis is a blood clot. An embolism is a piece of blood or fat clot that has broken off and travels in the bloodstream. What condition results when an embolism lodges: In a coronary artery? In the brain? In the lungs? What is a procedure to inject dye into the arteries and x-ray to see if there is narrowing (sclerosis) of a vessel? If an artery is too narrow, what procedure can be performed to open it up? If the embolism lodges in the coronary arteries - myocardial infarct (Heart attack). If the embolism lodges in an artery in the brain -- stroke If the embolism lodges in the lungs- pulmonary embolism An ANGIOGRAM An ANGIOPLASTY What procedure can be done when a Coronary artery has become almost completely blocked from plaques and requires a vessel transplant? What vessel is used for this procedure? CORONARY BYPASS. saphenous vein What is a sac-like outpouching of an artery? What is the result if it is located in the brain, and ruptures? Aneurysm Stroke Coronary artery disease terms: Atherosclerosis- Fatty deposits Angina pectoris- chest pain Myocardial infarction- blocked coronary artery -What is Silent Ischemia? Silent ischemia- lack of blood flow that happens to not cause any pain or other symptoms; leads to unexpected heart attack. What is Congestive Heart failure? Congestive Heart failure: -What is ATHEROSCLEROSIS? -What is Angina Pectoris? -What is Myocardial infarction? Describe some traits: Progressive weakening of the heart Blood backs up into lungs (may clog up blood) Cannot meet the body’s demands for oxygenated blood. What is Hypertrophic Cardiomyopathy? Define Embryonic Development of the Heart: -When does the heart first start beating? at the start of the fourth week Hypertrophic cardiomyopathy is a congenital condition where the walls of the left ventricle are so thick that the lumen is too small to hold much blood. The foramen ovale in the fetus gives rise to what structure in the adult? FOSSA OVALIS.