Methods for pattern discovery in unaligned biological sequences
... Pattern discovery in biological sequences is the problem of ®nding patterns that are overrepresented in a set of unaligned DNA or protein sequences of related biological function. Such patterns could correspond to regions of the sequences responsible for the function itself, and could be used later ...
... Pattern discovery in biological sequences is the problem of ®nding patterns that are overrepresented in a set of unaligned DNA or protein sequences of related biological function. Such patterns could correspond to regions of the sequences responsible for the function itself, and could be used later ...
ADP Ribosylation Factor is an Essential Protein in Saccharomyces cerevisiae and is Encoded by Two Genes.
... in press. Based on the in vitro ADP-ribosylation assay (36), ARF has been purified from a number of tissues, including bovine brain, in which ARF represents as much as 1 to 2% of total cell protein. ARF protein is encoded by at least two genes in both cows (26, 39) and humans (3). The bovine ARFI ge ...
... in press. Based on the in vitro ADP-ribosylation assay (36), ARF has been purified from a number of tissues, including bovine brain, in which ARF represents as much as 1 to 2% of total cell protein. ARF protein is encoded by at least two genes in both cows (26, 39) and humans (3). The bovine ARFI ge ...
Gene Detection Systems Catalog
... helping them achieve success is a priority at Gene Link. These customers are located worldwide. Gene Link is a leading supplier of custom oligonucleotides for use in PCR, sequencing, cloning, and mutagenesis. Gene Link services include genotyping, sequencing and gene construction. Gene Link offers a ...
... helping them achieve success is a priority at Gene Link. These customers are located worldwide. Gene Link is a leading supplier of custom oligonucleotides for use in PCR, sequencing, cloning, and mutagenesis. Gene Link services include genotyping, sequencing and gene construction. Gene Link offers a ...
Localization and structural analysis of the ribosomal RNA operons of
... E. coli rRNA operons. The fact that insertion of a cartridge resulted in the loss of the wild type signal, leads to the conclusion that there are only three rRNA operons in R. sphaeroides. Thus rmA can be assigned to the 10 kb BamYU signal, rrnB to the 14 kb BamYU signal, and rmC to the 13 kb BamYU ...
... E. coli rRNA operons. The fact that insertion of a cartridge resulted in the loss of the wild type signal, leads to the conclusion that there are only three rRNA operons in R. sphaeroides. Thus rmA can be assigned to the 10 kb BamYU signal, rrnB to the 14 kb BamYU signal, and rmC to the 13 kb BamYU ...
Maintenance of genomic integrity by p53: complementary
... S phase arrest In another checkpoint response pathway which operates in S phase and slows down the rate of DNA replication, p21Waf1 binds to the proliferatingcell nuclear antigen (PCNA) and blocks its activity, interfering with cell-cycle progression by blocking the elongation step in DNA replicatio ...
... S phase arrest In another checkpoint response pathway which operates in S phase and slows down the rate of DNA replication, p21Waf1 binds to the proliferatingcell nuclear antigen (PCNA) and blocks its activity, interfering with cell-cycle progression by blocking the elongation step in DNA replicatio ...
Bacteriophage A cloning system for the construction of
... (MCS) containing single recognition sequences for the restriction enzymes BamHI, EcoRI, and HindIII (P.S.M., J. V. Knowlton, and M.L.B., unpublished data). To use this vector for directional cloning, a method for preparing cDNA fragments with appropriate cohesive termini was needed. The methods avai ...
... (MCS) containing single recognition sequences for the restriction enzymes BamHI, EcoRI, and HindIII (P.S.M., J. V. Knowlton, and M.L.B., unpublished data). To use this vector for directional cloning, a method for preparing cDNA fragments with appropriate cohesive termini was needed. The methods avai ...
Test Info Sheet
... Pontocerebellar hypoplasia (PCH) is a rare disorder affecting the ventral pons and cerebellum, two structures that share the same neuronal lineage during brain development. PCH has a fetal onset in most cases and appears to result from a combination of a developmental defect and progressive atrophy ...
... Pontocerebellar hypoplasia (PCH) is a rare disorder affecting the ventral pons and cerebellum, two structures that share the same neuronal lineage during brain development. PCH has a fetal onset in most cases and appears to result from a combination of a developmental defect and progressive atrophy ...
Transcription
... metabolic activities. In present day cells, DNA stores information and proteins perform catalysis, with RNA as the intermediate between DNA and protein. One can imagine a time when there was no DNA or protein, just RNA performing both functions: this is the RNA World hypothesis. • Very long ago, at ...
... metabolic activities. In present day cells, DNA stores information and proteins perform catalysis, with RNA as the intermediate between DNA and protein. One can imagine a time when there was no DNA or protein, just RNA performing both functions: this is the RNA World hypothesis. • Very long ago, at ...
exploring genetics - Cold Spring Harbor Laboratory
... Standard Course of Study for the middle school grades. The career information, reflection activities, and the inquiry based nature of the activities provide a well rounded introduction to genetic science and its relation to mathematics at the middle grades level. The kit was developed as an outreach ...
... Standard Course of Study for the middle school grades. The career information, reflection activities, and the inquiry based nature of the activities provide a well rounded introduction to genetic science and its relation to mathematics at the middle grades level. The kit was developed as an outreach ...
Chapter 29 Slides
... Transferred Between Bacteria • In 1946, Lederberg and Tatum showed that two different strains of bacteria with different growth requirements could exchange genes • Lederberg and Tatum surmised that the bacterial cells must interact with each other - the process is now known as sexual conjugation ...
... Transferred Between Bacteria • In 1946, Lederberg and Tatum showed that two different strains of bacteria with different growth requirements could exchange genes • Lederberg and Tatum surmised that the bacterial cells must interact with each other - the process is now known as sexual conjugation ...
Recombinant Materials Form
... (other than Escherichia coli cloning selection)? Could this acquisition compromise the use of the drug to control disease agents in humans, veterinary medicine, or agriculture? 19. Will this experiment involve the cloning of toxin molecules with LD50 of less than 100 Nanograms per Kilogram body weig ...
... (other than Escherichia coli cloning selection)? Could this acquisition compromise the use of the drug to control disease agents in humans, veterinary medicine, or agriculture? 19. Will this experiment involve the cloning of toxin molecules with LD50 of less than 100 Nanograms per Kilogram body weig ...
Engineered bacteriophage-defence systems in bioprocessing
... products; however, they are often used together during the production of Cheddar cheese16. In this case, the thermophilic and mesophilic components are phage unrelated, and one of the two components will continue to produce acid if the other is lysed by phages. The availability of a growing number o ...
... products; however, they are often used together during the production of Cheddar cheese16. In this case, the thermophilic and mesophilic components are phage unrelated, and one of the two components will continue to produce acid if the other is lysed by phages. The availability of a growing number o ...
A Novel CpG Island Set Identifies Tissue-Specific
... fractions were interrogated by PCR using primers specific for a range of known CGIs and non-CGI sequences (Figure 1C). For example, the nonmethylated CGI of the P48 gene eluted at high salt. The X-linked monoamine oxidase (MAO) gene eluted as a single high salt peak from male genomic DNA (where it is ...
... fractions were interrogated by PCR using primers specific for a range of known CGIs and non-CGI sequences (Figure 1C). For example, the nonmethylated CGI of the P48 gene eluted at high salt. The X-linked monoamine oxidase (MAO) gene eluted as a single high salt peak from male genomic DNA (where it is ...
ARTICLES - Weizmann Institute of Science
... expressed genes. Consistent with this expectation, the highly expressed ribosomal RNA and transfer RNA genes stood out as having markedly low predicted nucleosome occupancy. In contrast to the ubiquitously expressed tRNAs, many other genes vary their expression between high and low levels in differe ...
... expressed genes. Consistent with this expectation, the highly expressed ribosomal RNA and transfer RNA genes stood out as having markedly low predicted nucleosome occupancy. In contrast to the ubiquitously expressed tRNAs, many other genes vary their expression between high and low levels in differe ...
2.2 Australian Pilot Survey for GM Food Labelling
... selected products were also asked to present evidence on how they determined the GM status of their food products. All 51 samples tested complied with the GM food labelling requirements of Standard 1.5.2. GM material within the 1% limit of the labelling exemption for unintentional presence of an app ...
... selected products were also asked to present evidence on how they determined the GM status of their food products. All 51 samples tested complied with the GM food labelling requirements of Standard 1.5.2. GM material within the 1% limit of the labelling exemption for unintentional presence of an app ...
Three-dimensional Structures of Bulge
... resulting in a non-functioning gene product. Frameshifts that result from unpaired nucleotides can arise from recombination processes or from displacement of bases during replication (Streisinger et al., 1966), e.g. when the template strand contains an unpaired base, the progeny strand will contain ...
... resulting in a non-functioning gene product. Frameshifts that result from unpaired nucleotides can arise from recombination processes or from displacement of bases during replication (Streisinger et al., 1966), e.g. when the template strand contains an unpaired base, the progeny strand will contain ...
PDF
... between GC content and divergence (Rs = -0.019, P = 0.649) or intron length (Rs = 0.000, P = 0.993) was observed (Fig. 5). We also calculated the relationship between GC content and divergence and intron length in the two datasets (first and non-first intron). Similarly, no significant relationships ...
... between GC content and divergence (Rs = -0.019, P = 0.649) or intron length (Rs = 0.000, P = 0.993) was observed (Fig. 5). We also calculated the relationship between GC content and divergence and intron length in the two datasets (first and non-first intron). Similarly, no significant relationships ...
Meiosis and Sexual Life Cycles
... Transmitting chromosomes and genetic information from generation to generation is equally important. A critical role of heredity is to maintain and obtain variation among members of a species. These variations are the result of the specific genes we inherit from our parents. We did not always know t ...
... Transmitting chromosomes and genetic information from generation to generation is equally important. A critical role of heredity is to maintain and obtain variation among members of a species. These variations are the result of the specific genes we inherit from our parents. We did not always know t ...
3-A Notes
... *Karyotypes are species specific *Chromosomes are arranged according to size and position of the centromere *Human karyotype shows 46 chromosomes: autosomal (1-22) and sex (23) *They are numbered largest to smallest to help in identification *They are also arranged together with ...
... *Karyotypes are species specific *Chromosomes are arranged according to size and position of the centromere *Human karyotype shows 46 chromosomes: autosomal (1-22) and sex (23) *They are numbered largest to smallest to help in identification *They are also arranged together with ...
Mendelian Genetics
... *Karyotypes are species specific *Chromosomes are arranged according to size and position of the centromere *Human karyotype shows 46 chromosomes: autosomal (1-22) and sex (23) *They are numbered largest to smallest to help in identification *They are also arranged together with ...
... *Karyotypes are species specific *Chromosomes are arranged according to size and position of the centromere *Human karyotype shows 46 chromosomes: autosomal (1-22) and sex (23) *They are numbered largest to smallest to help in identification *They are also arranged together with ...
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... earliest times. In recent years, breeding for resistance against disease proved to be as important for total wheat production, as breeding for an increase in yield potential (Byerlee & Moya, 1993). The use of single resistance genes against various pests and diseases plays a major role in resistance ...
... earliest times. In recent years, breeding for resistance against disease proved to be as important for total wheat production, as breeding for an increase in yield potential (Byerlee & Moya, 1993). The use of single resistance genes against various pests and diseases plays a major role in resistance ...
MAK, a computational tool kit for automated MITE
... with minimal damages to the TIRs. An additional long element (AB025602, from 7658 to 11 849) showed an overall 98% DNA sequence identity to A-MathE1. Since the element on AB025602 is situated on a different locus of chromosome 5 from A-MathE1 on AC007123 and they share no flanking sequence similarit ...
... with minimal damages to the TIRs. An additional long element (AB025602, from 7658 to 11 849) showed an overall 98% DNA sequence identity to A-MathE1. Since the element on AB025602 is situated on a different locus of chromosome 5 from A-MathE1 on AC007123 and they share no flanking sequence similarit ...
Transgenic approaches for optogenetics Tim Murphy UBC.
... The tamoxifen-inducible Cre strain, B6.Cg-Tg(CAG-cre/Esr1)5Amc/J (004682), is used to conditionally delete floxed sequences throughout the entire mouse because its promoter (beta actin) should have ubiquitous expression. Data collected by the JAX Cre Resource show that tamoxifen induction is more ro ...
... The tamoxifen-inducible Cre strain, B6.Cg-Tg(CAG-cre/Esr1)5Amc/J (004682), is used to conditionally delete floxed sequences throughout the entire mouse because its promoter (beta actin) should have ubiquitous expression. Data collected by the JAX Cre Resource show that tamoxifen induction is more ro ...
CTY Genetics Syllabus
... • Lecture/Class Notes: DNA Replication (45 minutes) • Activity: Human PCR Machines (30 minutes) • Lecture/Class Notes: Mutations in DNA (45 minutes) Afternoon (120 minutes) • Lecture/Class Notes- Epigenetics, Imprinting and Disease (60 minutes) • Class Discussion- Nuclear Reprogramming (20 minutes) ...
... • Lecture/Class Notes: DNA Replication (45 minutes) • Activity: Human PCR Machines (30 minutes) • Lecture/Class Notes: Mutations in DNA (45 minutes) Afternoon (120 minutes) • Lecture/Class Notes- Epigenetics, Imprinting and Disease (60 minutes) • Class Discussion- Nuclear Reprogramming (20 minutes) ...
Solid Tumour Section Esophagus: Barrett's esophagus, dysplasia and adenocarcinoma
... weight loss, pain in the throat or mid-chest, etc. ...
... weight loss, pain in the throat or mid-chest, etc. ...
Extrachromosomal DNA
Extrachromosomal DNA is any DNA that is found outside of the nucleus of a cell. It is also referred to as extranuclear DNA or cytoplasmic DNA. Most DNA in an individual genome is found in chromosomes but DNA found outside of the nucleus also serves important biological functions.In prokaryotes, nonviral extrachromosomal DNA is primarily found in plasmids whereas in eukaryotes extrachromosomal DNA is primarily found in organelles. Mitochondrial DNA is a main source of this extrachromosomal DNA in eukaryotes. Extrachromosomal DNA is often used in research of replication because it is easy to identify and isolate.Extrachromosomal DNA was found to be structurally different from nuclear DNA. Cytoplasmic DNA is less methylated than DNA found within the nucleus. It was also confirmed that the sequences of cytoplasmic DNA was different from nuclear DNA in the same organism, showing that cytoplasmic DNAs are not simply fragments of nuclear DNA.In addition to DNA found outside of the nucleus in cells, infection of viral genomes also provides an example of extrachromosomal DNA.