Review of the p53 Tumor Suppressor Gene and its Role in Gliomas
... Tumorigenesis is the process by which a normal cell deviates from its typical pattern of development and attains a distinct cancerous phenotype. ...
... Tumorigenesis is the process by which a normal cell deviates from its typical pattern of development and attains a distinct cancerous phenotype. ...
Familial Alzheimer`s Disease–Linked Presenilin 1 Variants Elevate
... in the brains of young transgenic animals coexpressing a chimeric amyloid precursor protein (APP) and an FAD-linked PS1 variant compared with brains of transgenic mice expressing APP alone or transgenic mice coexpressing wild-type human PS1 and APP. These studies provide compelling support for the v ...
... in the brains of young transgenic animals coexpressing a chimeric amyloid precursor protein (APP) and an FAD-linked PS1 variant compared with brains of transgenic mice expressing APP alone or transgenic mice coexpressing wild-type human PS1 and APP. These studies provide compelling support for the v ...
STICKLER SYNDROME - Stickler Involved People
... Wagner syndrome, Marshall syndrome, and the Weissenbacher-Zweymuller syndrome are often confused with Stickler syndrome. Historically, there has been a debate between “lumpers” and “splitters” as to whether the disorders are phenotypic variants of the same syndrome or distinct phenotypic entities. W ...
... Wagner syndrome, Marshall syndrome, and the Weissenbacher-Zweymuller syndrome are often confused with Stickler syndrome. Historically, there has been a debate between “lumpers” and “splitters” as to whether the disorders are phenotypic variants of the same syndrome or distinct phenotypic entities. W ...
Warren, ST and Ashley, CT: Triplet repeat expansion mutations: The example of fragile X syndrome. Annual Review of Neuroscience 18:77-99 (1995).
... et al ( 1991) and Verkerk et al (1991) concurrently yet independently identified a single restriction fragment of approximately 5 kb that contained both the proximal and distal fragile X hybrid breakpoints and also detected length variation in fragile X patients on Southern blots. Kremer et al ( 199 ...
... et al ( 1991) and Verkerk et al (1991) concurrently yet independently identified a single restriction fragment of approximately 5 kb that contained both the proximal and distal fragile X hybrid breakpoints and also detected length variation in fragile X patients on Southern blots. Kremer et al ( 199 ...
Genetic analysis of non-syndromic craniosynostosis
... syndromes (10, 11). We have initiated collaboration among leading medical institutions to accrue families with at least one individual with NSC. The clinical characterization of probands and other affected family members is conducted in a highly organized and detailed fashion using standardized eval ...
... syndromes (10, 11). We have initiated collaboration among leading medical institutions to accrue families with at least one individual with NSC. The clinical characterization of probands and other affected family members is conducted in a highly organized and detailed fashion using standardized eval ...
Health consequences of adult hypolactasia
... (probably fermented by colonic bacterial flora – creating flatulence and abdominal pains) -> severe diarrhea followed by dehydration, metabolic acidosis and weight loss are usually diagnosed during the first weeks or month of life! ...
... (probably fermented by colonic bacterial flora – creating flatulence and abdominal pains) -> severe diarrhea followed by dehydration, metabolic acidosis and weight loss are usually diagnosed during the first weeks or month of life! ...
Primary amenorrhea
... Molecular diagnosis of 5a reductase deficiency In 4 elite young female athletes through hormonal screening for hyperandrogenism. P Fenichel, F. Paris… and Ch Sultan ...
... Molecular diagnosis of 5a reductase deficiency In 4 elite young female athletes through hormonal screening for hyperandrogenism. P Fenichel, F. Paris… and Ch Sultan ...
amyotrophic lateral sclerosis - Muscular Dystrophy Association
... tubes, the average life expectancy is three to five years after an ALS diagnosis. About 4 to 10 percent of those with the disease live more than 10 years, and some survive for decades, such as British physicist Stephen Hawking, who has had ALS since the 1960s and is still able to practice his profes ...
... tubes, the average life expectancy is three to five years after an ALS diagnosis. About 4 to 10 percent of those with the disease live more than 10 years, and some survive for decades, such as British physicist Stephen Hawking, who has had ALS since the 1960s and is still able to practice his profes ...
The disease characteristics of different strains of scrapie in Sinc
... V M - S i n c s7 congenic mice makes it possible to study the effect o f the Sinc gene, minimizing the complication o f effects of these other genes. The results shown in Table 2 and Fig. 4 confirm that the Sinc gene has an overwhelming influence on the timing of events in scrapie pathogenesis. The ...
... V M - S i n c s7 congenic mice makes it possible to study the effect o f the Sinc gene, minimizing the complication o f effects of these other genes. The results shown in Table 2 and Fig. 4 confirm that the Sinc gene has an overwhelming influence on the timing of events in scrapie pathogenesis. The ...
The role of tumor necrosis factor-alpha
... some cytokine gene polymorphisms were analyzed for susceptibility to the disease. The aim of this study was to investigate the role of tumor necrosis factor-alpha (TNF-α) -308 G/A and transforming growth factor-beta 1 (TGF-β1) –915 G/C polymorphisms in the development and clinical progression of chi ...
... some cytokine gene polymorphisms were analyzed for susceptibility to the disease. The aim of this study was to investigate the role of tumor necrosis factor-alpha (TNF-α) -308 G/A and transforming growth factor-beta 1 (TGF-β1) –915 G/C polymorphisms in the development and clinical progression of chi ...
2. Eyespot - MacKillop Farm Management Group
... Compass and Trojan which both exhibit low incidences of eyespot. 2. Many varieties are not consistent in their response to eyespot. These include Hindmarsh, La Trobe, Corack and Shield, which often, but not always, exhibit high incidences of eyespot. Where eyespot inoculum is present in paddocks at ...
... Compass and Trojan which both exhibit low incidences of eyespot. 2. Many varieties are not consistent in their response to eyespot. These include Hindmarsh, La Trobe, Corack and Shield, which often, but not always, exhibit high incidences of eyespot. Where eyespot inoculum is present in paddocks at ...
p53 in Hematologic Malignancies
... have activation of the c-myc gene. Although T-cell leukemia Cases of AML and MDS have been reported that have cell lines have about a 50% frequency of p53 mutations,"" high levels of p53 protein, as determined by either immunoprecipitation or immunochemistry, buthaveno detectable p53 mutations are r ...
... have activation of the c-myc gene. Although T-cell leukemia Cases of AML and MDS have been reported that have cell lines have about a 50% frequency of p53 mutations,"" high levels of p53 protein, as determined by either immunoprecipitation or immunochemistry, buthaveno detectable p53 mutations are r ...
CCA Summer 2004 Newsletter - Children`s Craniofacial Association
... palate, but it can also be due to abnormal function of the nerves of hearing. Individuals with CCD typically have normal ability to learn. Affected, infants and children usually reach their developmental milestones as expected. Children may benefit from speech therapy, especially while undergoing tr ...
... palate, but it can also be due to abnormal function of the nerves of hearing. Individuals with CCD typically have normal ability to learn. Affected, infants and children usually reach their developmental milestones as expected. Children may benefit from speech therapy, especially while undergoing tr ...
adenomi ipofisari familiari
... parathyroidectomy(at least 3.5 glands) or total parathyroidectomy is recommended . Total para- thyroidectomy with autotransplantation may be considered ...
... parathyroidectomy(at least 3.5 glands) or total parathyroidectomy is recommended . Total para- thyroidectomy with autotransplantation may be considered ...
The amelogenin gene
... of the developing enamel matrix. This protein is now well characterized from the data of amino acid sequences which have been shown to be at a high degree of homology between all species investigated to date. The gene structure of this protein has been demonstrated and it is confirmed that there are ...
... of the developing enamel matrix. This protein is now well characterized from the data of amino acid sequences which have been shown to be at a high degree of homology between all species investigated to date. The gene structure of this protein has been demonstrated and it is confirmed that there are ...
Evaluation and Treatment of Constipation in Infants and Children
... identify randomized controlled trials. This strategy includes controlled vocabulary and free-text terms such as randomized controlled trial, clinical trial, and placebo (9). When this search strategy was run with the term constipation, 1047 articles were identified, 809 of which were in English and ...
... identify randomized controlled trials. This strategy includes controlled vocabulary and free-text terms such as randomized controlled trial, clinical trial, and placebo (9). When this search strategy was run with the term constipation, 1047 articles were identified, 809 of which were in English and ...
Genetic aspects in sarcoidosis REVIEW M. Luisetti*, A. Beretta*, L. Casali*
... sarcoidosis was comparable, being 3.6±4.7% in Finland and 2.9±4.3% in Hokkaido [35], in spite of the marked difference of overall prevalence of the disease between the two regions (28.2 versus 3.7 per 100,000, respectively) [15]. The most informative study in this field was conducted in the Detroit ...
... sarcoidosis was comparable, being 3.6±4.7% in Finland and 2.9±4.3% in Hokkaido [35], in spite of the marked difference of overall prevalence of the disease between the two regions (28.2 versus 3.7 per 100,000, respectively) [15]. The most informative study in this field was conducted in the Detroit ...
Chapter 15
... exhibited greater longevity than non-aa genotypes when reared on various concentrations of dry yeast in the food medium (Thomas, 1991). This life-span extension was observed for all yeast concentrations, except for the concentration used by Templeton (1982, 1983), which reduced life span. Thus, nutr ...
... exhibited greater longevity than non-aa genotypes when reared on various concentrations of dry yeast in the food medium (Thomas, 1991). This life-span extension was observed for all yeast concentrations, except for the concentration used by Templeton (1982, 1983), which reduced life span. Thus, nutr ...
Gene Ontology (GO) Tutorial
... Method/Algorithm Description To provide the most detailed information available, genes are directly associated with GO terms that are as granular as possible. However, for many purposes, such as analyzing the results of microarray expression data, it is very useful to "calculate" on GO, moving up th ...
... Method/Algorithm Description To provide the most detailed information available, genes are directly associated with GO terms that are as granular as possible. However, for many purposes, such as analyzing the results of microarray expression data, it is very useful to "calculate" on GO, moving up th ...
gsea user guide
... uses the 3 values in class_A and the 15 values in class_B to score the gene by its differential expression. In the signal-tonoise calculation, the mean and variance estimates for the gene are based on different sample sizes; a situation which it would be better to avoid. (If you wish, you can use ex ...
... uses the 3 values in class_A and the 15 values in class_B to score the gene by its differential expression. In the signal-tonoise calculation, the mean and variance estimates for the gene are based on different sample sizes; a situation which it would be better to avoid. (If you wish, you can use ex ...
Signaling Pathways of Heme Oxygenase
... others who demonstrated that HO-derived bilirubin provides cellular protection to neuronal cells (Dore et al., 1999). A comprehensive overview on the protective effects of bilirubin has recently been given by Kapitulnik (2004). ...
... others who demonstrated that HO-derived bilirubin provides cellular protection to neuronal cells (Dore et al., 1999). A comprehensive overview on the protective effects of bilirubin has recently been given by Kapitulnik (2004). ...
hematology case study: a hypochromic, microcytic anemia
... anemia and increased FEP along with normal serum iron would be characteristic of lead poisoning. Again, referring to the question posed at the end of the case study, what other information would be useful to confirm the diagnosis? In this patient, a healthy active young man, anemia of chronic diseas ...
... anemia and increased FEP along with normal serum iron would be characteristic of lead poisoning. Again, referring to the question posed at the end of the case study, what other information would be useful to confirm the diagnosis? In this patient, a healthy active young man, anemia of chronic diseas ...