CT Tumor Volume Change - QIBA Wiki
... 2. A measured change in tumor volume that exceeds the relevant precision value in the table indicates 95% confidence in the presence of a true change. 3. Minimum detectable differences calculated from the following formula: 1.96 x sqrt [2 x (wCV2 + bias2)], where wCV is estimated from the square roo ...
... 2. A measured change in tumor volume that exceeds the relevant precision value in the table indicates 95% confidence in the presence of a true change. 3. Minimum detectable differences calculated from the following formula: 1.96 x sqrt [2 x (wCV2 + bias2)], where wCV is estimated from the square roo ...
TNM Staging of Head and Neck Cancer and Neck Dissection
... original source for this material is the AJCC Cancer Staging Manual, Seventh Edition (2010), published by Springer Science and Business Media LLC, www.springer.com. All photos have been graciously donated by Richard V. Smith, MD. ...
... original source for this material is the AJCC Cancer Staging Manual, Seventh Edition (2010), published by Springer Science and Business Media LLC, www.springer.com. All photos have been graciously donated by Richard V. Smith, MD. ...
RET Aberrations in Diverse Cancers
... before paired-end sequencing on the Illumina HiSeq2000 platform. Hybridization selection is performed using individually synthesized baits targeting the exons of 182 or 236 cancer-related genes and the introns of 14 or 19 genes frequently rearranged in cancer (Supplementary Table S4). Sequence data ...
... before paired-end sequencing on the Illumina HiSeq2000 platform. Hybridization selection is performed using individually synthesized baits targeting the exons of 182 or 236 cancer-related genes and the introns of 14 or 19 genes frequently rearranged in cancer (Supplementary Table S4). Sequence data ...
4.4. Assessment Procedure: Tumor Volume - QIBA Wiki
... Q. Should we specify all three levels (Acceptable, Target, Ideal) for each parameter? A. No. As much as possible, provide just the Acceptable value. The Acceptable values should be selected such that the profile claim will be satisfied. ...
... Q. Should we specify all three levels (Acceptable, Target, Ideal) for each parameter? A. No. As much as possible, provide just the Acceptable value. The Acceptable values should be selected such that the profile claim will be satisfied. ...
Preclinical Activity of Nanoliposomal Irinotecan
... (lung), LoVo (colon), MDA-MB-231 (breast)] were obtained from the ATCC, whereas A2780 cells (ovarian) was obtained from Sigma-Aldrich. Cells from the ATCC and Sigma were received in 2010. All cells were authenticated before receipt and were propagated for less than 6 months after resuscitation. Cult ...
... (lung), LoVo (colon), MDA-MB-231 (breast)] were obtained from the ATCC, whereas A2780 cells (ovarian) was obtained from Sigma-Aldrich. Cells from the ATCC and Sigma were received in 2010. All cells were authenticated before receipt and were propagated for less than 6 months after resuscitation. Cult ...
Stage IA Ovarian Cancers
... Our study was undertaken after approval was received from the Institutional Review Board of the Cancer Institute Hospital of the Japanese Foundation for Cancer Research. From April 2000 to December 2009, 151 patients referred to our hospital with suspected gynecologic malignancies who underwent surg ...
... Our study was undertaken after approval was received from the Institutional Review Board of the Cancer Institute Hospital of the Japanese Foundation for Cancer Research. From April 2000 to December 2009, 151 patients referred to our hospital with suspected gynecologic malignancies who underwent surg ...
Skin cancer in Australia - Australian Institute of Health and Welfare
... squamous cell carcinoma (SCC). In 2002, BCC accounted for about two-thirds of NMSC cases, with most other NMSC comprising SCC (Staples et al. 2006). There are also other rare types of NMSC, which include, but are not limited to Merkel cell carcinoma, dermatofibrosarcoma, and cutaneous lymphoma (see ...
... squamous cell carcinoma (SCC). In 2002, BCC accounted for about two-thirds of NMSC cases, with most other NMSC comprising SCC (Staples et al. 2006). There are also other rare types of NMSC, which include, but are not limited to Merkel cell carcinoma, dermatofibrosarcoma, and cutaneous lymphoma (see ...
Skin cancer in Australia - Australian Melanoma Research Foundation
... squamous cell carcinoma (SCC). In 2002, BCC accounted for about two-thirds of NMSC cases, with most other NMSC comprising SCC (Staples et al. 2006). There are also other rare types of NMSC, which include, but are not limited to Merkel cell carcinoma, dermatofibrosarcoma, and cutaneous lymphoma (see ...
... squamous cell carcinoma (SCC). In 2002, BCC accounted for about two-thirds of NMSC cases, with most other NMSC comprising SCC (Staples et al. 2006). There are also other rare types of NMSC, which include, but are not limited to Merkel cell carcinoma, dermatofibrosarcoma, and cutaneous lymphoma (see ...
HPV-associated lung cancers: an international pooled analysis
... from the initial reaction in a final reaction volume of 25 µl. The cycling conditions were 95°C for 10 min, 40 cycles of 95°C for 1 min, 55°C for 1 min and 72°C for 1 min, followed by a final extension at 72°C for 5 min. Negative and positive controls were included in each PCR reaction. The PCR prod ...
... from the initial reaction in a final reaction volume of 25 µl. The cycling conditions were 95°C for 10 min, 40 cycles of 95°C for 1 min, 55°C for 1 min and 72°C for 1 min, followed by a final extension at 72°C for 5 min. Negative and positive controls were included in each PCR reaction. The PCR prod ...
NS-LIJ Powerpoint Template
... illogic of the judgment that the cystic sebaceous neoplasm… was related to conventional sebaceous adenoma... Scrutiny again, after a period of several years, of examples of "cystic sebaceous adenoma" pictured in Neoplasms with Sebaceous Differentiation, 1994 (and in the book devoted to Clues to Diag ...
... illogic of the judgment that the cystic sebaceous neoplasm… was related to conventional sebaceous adenoma... Scrutiny again, after a period of several years, of examples of "cystic sebaceous adenoma" pictured in Neoplasms with Sebaceous Differentiation, 1994 (and in the book devoted to Clues to Diag ...
THE INFLUENCE OF HEREDITY IN
... not yet been completely analyzed) has occurred in strains carrying primary liver tumors. 2. Every secondary tumor of the kidney m this stock hm occurred in strains carrying primary kidney tumors. 3. Every secondary lung tumor in this stock has occurred in strains carrying primary lung tumors (with t ...
... not yet been completely analyzed) has occurred in strains carrying primary liver tumors. 2. Every secondary tumor of the kidney m this stock hm occurred in strains carrying primary kidney tumors. 3. Every secondary lung tumor in this stock has occurred in strains carrying primary lung tumors (with t ...
Theranostics Tumor Quantification in Clinical Positron Emission
... the CT and PET images due to patient respiratory motion. The amount of mismatch and the effect on PET image values depend on the respiratory phase during which the CT scan is acquired. The mismatch causes error in the attenuation correction, which may degrade image quality and cause bias in the PET ...
... the CT and PET images due to patient respiratory motion. The amount of mismatch and the effect on PET image values depend on the respiratory phase during which the CT scan is acquired. The mismatch causes error in the attenuation correction, which may degrade image quality and cause bias in the PET ...
The long non-coding RNA HOTAIR is upregulated in endometrial
... overexpressed in a variety of human cancers, suggesting their involvement in tumorigenesis (15-19). However, the current knowledge is only the first step toward understanding the biological role of lncRNAs in cancer. Eventually, new discoveries will be used to design novel therapeutic agents (20), p ...
... overexpressed in a variety of human cancers, suggesting their involvement in tumorigenesis (15-19). However, the current knowledge is only the first step toward understanding the biological role of lncRNAs in cancer. Eventually, new discoveries will be used to design novel therapeutic agents (20), p ...
WHI Cancer Survivor Cohort Research Strategy
... invasive cancers. Of these, approximately 1/3 had died by September 2010 (Table 1). For the cancer sites selected for inclusion in the proposed Cancer Survivor Cohort (breast, colorectal, endometrial, lung, and ovarian cancers, lymphoma, leukemia, and melanoma), there are 16,727 centrally confirmed ...
... invasive cancers. Of these, approximately 1/3 had died by September 2010 (Table 1). For the cancer sites selected for inclusion in the proposed Cancer Survivor Cohort (breast, colorectal, endometrial, lung, and ovarian cancers, lymphoma, leukemia, and melanoma), there are 16,727 centrally confirmed ...
Chromosomal copy number alterations for associations of ductal
... from cross-sectional samples, by both targeted sequencing [12] and whole genome sequencing [10], to identify genomic changes that occur in progression from these pathologically defined neoplasias. These data have identified specific genomic changes to pathologic lesions defined by morphology whose r ...
... from cross-sectional samples, by both targeted sequencing [12] and whole genome sequencing [10], to identify genomic changes that occur in progression from these pathologically defined neoplasias. These data have identified specific genomic changes to pathologic lesions defined by morphology whose r ...
Telomerase activity in ductal carcinoma in situ and invasive breast
... invasive cancer samples (100%) had detectable telomerase activity (see Figure 2 and Table 1). In order to determine if telomerase activity was higher in invasive breast cancer than in DCIS lesions with detectable telomerase activity, we quanti®ed telomerase in a subset of patients in which sucient ...
... invasive cancer samples (100%) had detectable telomerase activity (see Figure 2 and Table 1). In order to determine if telomerase activity was higher in invasive breast cancer than in DCIS lesions with detectable telomerase activity, we quanti®ed telomerase in a subset of patients in which sucient ...
GI-neoplasms-(old-M
... *Some cases of Turcot’s syndrome have mutations in APC gene, Some cases of Turcot’s syndrome have germline mutations in mismatch repair genes (hMLH1 and hPMS2). **Attenuated familial polyposis coli and hereditary flat adenoma syndrome most likely are the same disorder, but they are listed separately ...
... *Some cases of Turcot’s syndrome have mutations in APC gene, Some cases of Turcot’s syndrome have germline mutations in mismatch repair genes (hMLH1 and hPMS2). **Attenuated familial polyposis coli and hereditary flat adenoma syndrome most likely are the same disorder, but they are listed separately ...
Knowledge Discovery and Predictive Modeling from Brain Tumor MRIs
... • Predictive Modeling: Machine learning is essential in developing image-guided predictive models. With the emergence of a large variety of clinical data, it remains an open question how data science techniques, such as machine learning and data mining, help build effective clinical decision-support ...
... • Predictive Modeling: Machine learning is essential in developing image-guided predictive models. With the emergence of a large variety of clinical data, it remains an open question how data science techniques, such as machine learning and data mining, help build effective clinical decision-support ...
DISEASE OF THE OVARY AND FALLOPAIN TUBE
... Complications of Ovarian Tumors This is the commonest complication and may occur with any tumor except those with adhesions. The thin-walled veins of the pedicle are obstructed first while the arterial supply continues. As a result there is hemorrhage into the tumor and into the peritoneum, and if n ...
... Complications of Ovarian Tumors This is the commonest complication and may occur with any tumor except those with adhesions. The thin-walled veins of the pedicle are obstructed first while the arterial supply continues. As a result there is hemorrhage into the tumor and into the peritoneum, and if n ...
DNA methylation: potential biomarker in Hepatocellular Carcinoma
... was shown to be hypermethylated and associated with clinical parameters in HCC. It is a tumor suppressor gene that plays a role in cell cycle regulation [57]. It was methylated in many other cancers as well [58]. Beside earlier study by Yu et al. [56], Shim et al. [59] and Su et al. [60] also report ...
... was shown to be hypermethylated and associated with clinical parameters in HCC. It is a tumor suppressor gene that plays a role in cell cycle regulation [57]. It was methylated in many other cancers as well [58]. Beside earlier study by Yu et al. [56], Shim et al. [59] and Su et al. [60] also report ...
Document
... with unilateral involvement (LE 3).3,38,39,41 The current TNM classification makes a distinction between superficial and deep inguinal nodes, although clinically, and even histopathologically, it is difficult or impossible to distinguish between them. In the current classification, a single tumor-po ...
... with unilateral involvement (LE 3).3,38,39,41 The current TNM classification makes a distinction between superficial and deep inguinal nodes, although clinically, and even histopathologically, it is difficult or impossible to distinguish between them. In the current classification, a single tumor-po ...
Chromosomal copy number alterations for associations of ductal
... in situ hybridization-based assay to measure copy number at these loci in DCIS samples. Clinicopathologic data were extracted from the electronic medical records of Stanford Cancer Institute and linked to demographic data from the population-based California Cancer Registry; results were integrated ...
... in situ hybridization-based assay to measure copy number at these loci in DCIS samples. Clinicopathologic data were extracted from the electronic medical records of Stanford Cancer Institute and linked to demographic data from the population-based California Cancer Registry; results were integrated ...
PDF - Gynecologic Oncology Research and Practice
... past decade. The most recent proposed division of EOC includes two distinct histologic groups: type I and type II cancers. It should be noted that the type I and type II classification is generally used to broadly classify ovarian neoplasms for research purposes based on their unique clinical and mo ...
... past decade. The most recent proposed division of EOC includes two distinct histologic groups: type I and type II cancers. It should be noted that the type I and type II classification is generally used to broadly classify ovarian neoplasms for research purposes based on their unique clinical and mo ...
The Origin and Pathogenesis of Epithelial Ovarian Cancer: A
... One of the major problems in elucidating the pathogenesis of ovarian cancer is that it is a heterogeneous disease composed of different types of tumors with widely differing clinicopathologic features and behavior. On the basis of a series of morphologic and molecular genetic studies, we have proposed ...
... One of the major problems in elucidating the pathogenesis of ovarian cancer is that it is a heterogeneous disease composed of different types of tumors with widely differing clinicopathologic features and behavior. On the basis of a series of morphologic and molecular genetic studies, we have proposed ...
Nanoproteomic analysis of ischemia-dependent changes
... Methods: Using NanoPro1000 technology, a rapid and highly sensitive immunoassay platform, the phosphorylation status of clinically relevant cancer-related biomarkers in response to ischemia was quantified in tissue samples from 20 patients with primary colorectal cancer. Tumor tissue and adjacent n ...
... Methods: Using NanoPro1000 technology, a rapid and highly sensitive immunoassay platform, the phosphorylation status of clinically relevant cancer-related biomarkers in response to ischemia was quantified in tissue samples from 20 patients with primary colorectal cancer. Tumor tissue and adjacent n ...