- CUNY Academic Works
... primary rewards acquire the ability to act as conditioned stimuli (CSs), which can elicit conditioned approach behaviors similar to the primary rewards with which they are associated. Involved in this type of learning is the brain’s reward system, the mesocorticolimbic dopamine (DA) system, which or ...
... primary rewards acquire the ability to act as conditioned stimuli (CSs), which can elicit conditioned approach behaviors similar to the primary rewards with which they are associated. Involved in this type of learning is the brain’s reward system, the mesocorticolimbic dopamine (DA) system, which or ...
Local network regulation of orexin neurons in the lateral hypothalamus
... will preferentially release glutamate and increase the excitability of postsynaptic orexin neurons. With higher firing frequencies, glutamate release becomes depressed (133), while peptide release would be favored. This will initially induce an inhibitory postsynaptic response due to the inhibitory ...
... will preferentially release glutamate and increase the excitability of postsynaptic orexin neurons. With higher firing frequencies, glutamate release becomes depressed (133), while peptide release would be favored. This will initially induce an inhibitory postsynaptic response due to the inhibitory ...
Serotonin modulates responses to species
... The serotonergic neurons that provide a large input to auditory nuclei are located in the dorsal raphe nucleus, and often fire in correlation with the level of arousal (Trulson and Jacobs 1979). Levels of serotonin in target regions of the brain are correspondingly higher during increased activity of ...
... The serotonergic neurons that provide a large input to auditory nuclei are located in the dorsal raphe nucleus, and often fire in correlation with the level of arousal (Trulson and Jacobs 1979). Levels of serotonin in target regions of the brain are correspondingly higher during increased activity of ...
The Dialectics of Hebb and Homeostasis within
... are likely to subserve distinct functions within neural circuits. Put another way, one could argue that if the response to a perturbation in activity is not a global scaling of synapses, then one is (by definition) not studying synaptic scaling. On the other hand, this “phenotypic” classification ap ...
... are likely to subserve distinct functions within neural circuits. Put another way, one could argue that if the response to a perturbation in activity is not a global scaling of synapses, then one is (by definition) not studying synaptic scaling. On the other hand, this “phenotypic” classification ap ...
Dopamine neurons projecting to the posterior striatum form an
... As previously reported, we found that dopamine neurons with distinct projection targets reside in different, but overlapping, areas of the midbrain (Figure 3; Figure 3-figure supplement 1; Figure 3-figure supplement 2; Figure 3-figure supplement 3) (Bjorklund and Dunnett, 2007; Haber, 2014; Lammel e ...
... As previously reported, we found that dopamine neurons with distinct projection targets reside in different, but overlapping, areas of the midbrain (Figure 3; Figure 3-figure supplement 1; Figure 3-figure supplement 2; Figure 3-figure supplement 3) (Bjorklund and Dunnett, 2007; Haber, 2014; Lammel e ...
cortical limbic system: a computational model. PhD thesis. htt
... when all I could think of was science. To Craig’s family for making me feel at home especially when I missed home. To my family, for all your support. I am indebted to them for the sacrifices that they made to put me through education. Thank you. ...
... when all I could think of was science. To Craig’s family for making me feel at home especially when I missed home. To my family, for all your support. I am indebted to them for the sacrifices that they made to put me through education. Thank you. ...
Inhibitory Gating of Basolateral Amygdala Inputs to the Prefrontal
... onto neighboring parvalbumin and somatostatin expressing interneurons. Inhibitory connections from these two populations of interneurons are also much stronger onto corticoamygdala neurons. Consequently, BLA inputs are able to drive robust feedforward inhibition via two parallel interneuron pathways ...
... onto neighboring parvalbumin and somatostatin expressing interneurons. Inhibitory connections from these two populations of interneurons are also much stronger onto corticoamygdala neurons. Consequently, BLA inputs are able to drive robust feedforward inhibition via two parallel interneuron pathways ...
Segregated cholinergic transmission in the ventral tegmental area
... axons (albeit not significant; Supplementary Fig. 4) and with an area of higher density in the dorsal part of the parabrachial pigmented area (Fig. 1c and 2c). Consecutive sections were processed to reveal the YFP by a permanent peroxidase reaction product and processed for electron microscopy to ch ...
... axons (albeit not significant; Supplementary Fig. 4) and with an area of higher density in the dorsal part of the parabrachial pigmented area (Fig. 1c and 2c). Consecutive sections were processed to reveal the YFP by a permanent peroxidase reaction product and processed for electron microscopy to ch ...
Corticotropin-Releasing Hormone Directly Activates Noradrenergic
... hydrate (400 mg/kg, i.p.) and perfused through the ascending aorta with an ice-cold, oxygenated (low Na/high sucrose) perfusion solution (in mM: 1.9 KCl, 1.2 Na2HPO4, 6 MgCl2, 33 NaHCO3, 20 glucose, and 229 sucrose saturated with 95% O2/5% CO2) (Aghajanian and Rasmussen, 1989). After decapitation, t ...
... hydrate (400 mg/kg, i.p.) and perfused through the ascending aorta with an ice-cold, oxygenated (low Na/high sucrose) perfusion solution (in mM: 1.9 KCl, 1.2 Na2HPO4, 6 MgCl2, 33 NaHCO3, 20 glucose, and 229 sucrose saturated with 95% O2/5% CO2) (Aghajanian and Rasmussen, 1989). After decapitation, t ...
Review Getting Formal with Dopamine and Reward
... [this issue of Neuron]) . The structures included the dopamine system, as many of the stimulation sites were in close proximity to axons of dopamine neurons or to axons presynaptic to them (Wise, 1996a). Finally, major drugs of abuse influence dopamine neurotransmission (Wise and Hoffman, 1992; Wise ...
... [this issue of Neuron]) . The structures included the dopamine system, as many of the stimulation sites were in close proximity to axons of dopamine neurons or to axons presynaptic to them (Wise, 1996a). Finally, major drugs of abuse influence dopamine neurotransmission (Wise and Hoffman, 1992; Wise ...
Central circuitries for body temperature regulation and fever
... understandings of the central circuitry mechanisms that underlie nonshivering thermogenesis in brown adipose tissue, shivering thermogenesis in skeletal muscles, thermoregulatory cardiac regulation, heat-loss regulation through cutaneous vasomotion, and ACTH release. To defend thermal homeostasis fr ...
... understandings of the central circuitry mechanisms that underlie nonshivering thermogenesis in brown adipose tissue, shivering thermogenesis in skeletal muscles, thermoregulatory cardiac regulation, heat-loss regulation through cutaneous vasomotion, and ACTH release. To defend thermal homeostasis fr ...
On-line Optical Operant Conditioning of Cortical Activity
... excellent temporal resolution, but do not permit recordings from the same identified neurons in dense local circuits over multiple days. Two-photon calcium imaging makes it possible to observe the activity of the same population of identified neurons in behaving animals over long time periods. Here ...
... excellent temporal resolution, but do not permit recordings from the same identified neurons in dense local circuits over multiple days. Two-photon calcium imaging makes it possible to observe the activity of the same population of identified neurons in behaving animals over long time periods. Here ...
Central circuitries for body temperature regulation and fever
... understandings of the central circuitry mechanisms that underlie nonshivering thermogenesis in brown adipose tissue, shivering thermogenesis in skeletal muscles, thermoregulatory cardiac regulation, heat-loss regulation through cutaneous vasomotion, and ACTH release. To defend thermal homeostasis fr ...
... understandings of the central circuitry mechanisms that underlie nonshivering thermogenesis in brown adipose tissue, shivering thermogenesis in skeletal muscles, thermoregulatory cardiac regulation, heat-loss regulation through cutaneous vasomotion, and ACTH release. To defend thermal homeostasis fr ...