Ricin Fact Sheet
... range. There are significant species differences in toxicity, up to 100 fold, rabbits being one of the more susceptible species. The human lethal dose by ingestion has been estimated as 1-20 mg/kg, and by injection 1-10 g/kg, but no reliable data exists. There is no documented information on confir ...
... range. There are significant species differences in toxicity, up to 100 fold, rabbits being one of the more susceptible species. The human lethal dose by ingestion has been estimated as 1-20 mg/kg, and by injection 1-10 g/kg, but no reliable data exists. There is no documented information on confir ...
Final Report on the Safety Assessment of Sodium Iodate
... oxidizing agent in cosmetics, but no current uses have been reported. It is approved by the European Union for use as a preservative in rinse-off cosmetic products at concentrations no greater than 0.1%. Pure Sodium Iodate is a sufficiently strong oxidizing agent that it presents a fire risk near or ...
... oxidizing agent in cosmetics, but no current uses have been reported. It is approved by the European Union for use as a preservative in rinse-off cosmetic products at concentrations no greater than 0.1%. Pure Sodium Iodate is a sufficiently strong oxidizing agent that it presents a fire risk near or ...
Datasheet Sodium Nitroprusside For Injection
... maximum rate, administration of sodium nitroprusside should be terminated immediately. Methaemoglobin normally present in the body can buffer a certain amount of CN-, but the capacity of this system is exhausted by the CN- produced from about 500 microgram/kg of sodium nitroprusside. This amount of ...
... maximum rate, administration of sodium nitroprusside should be terminated immediately. Methaemoglobin normally present in the body can buffer a certain amount of CN-, but the capacity of this system is exhausted by the CN- produced from about 500 microgram/kg of sodium nitroprusside. This amount of ...
International Journal of Ayurveda and Pharma Research
... generally believed to be safe. But due to its toxicity it causes adverse effect. Calotropis procera consumption are reported to cause blisters, lesions and eruptions when taken by patients for the treatment of joint pains and gastrointestinal problems caries tooth and ocular toxicity. The preparatio ...
... generally believed to be safe. But due to its toxicity it causes adverse effect. Calotropis procera consumption are reported to cause blisters, lesions and eruptions when taken by patients for the treatment of joint pains and gastrointestinal problems caries tooth and ocular toxicity. The preparatio ...
IOSR Journal of Environmental Science, Toxicology and Food Technology (IOSR-JESTFT)
... Botulinum is the first biological toxin that has licensed for treatment of human diseases. In United States, botulinum toxin is currently licensed for treatment of cervical torticollis, strabismus and blepharospasm associated with dystonia. It is also used ‘off label’ for a variety of more prevalent ...
... Botulinum is the first biological toxin that has licensed for treatment of human diseases. In United States, botulinum toxin is currently licensed for treatment of cervical torticollis, strabismus and blepharospasm associated with dystonia. It is also used ‘off label’ for a variety of more prevalent ...
BACILLUS SPHAERICUS TOXINS: Molecular Biology and Mode of
... B.sphaericus (56) is an aerobic bacterium that produces terminal spherical spores. It lacks several biochemical pathways and thus can not use sugars as metabolites. The findings of various genetic and biochemical studies indicate that this species is heterogeneous. The increasing number of isolated ...
... B.sphaericus (56) is an aerobic bacterium that produces terminal spherical spores. It lacks several biochemical pathways and thus can not use sugars as metabolites. The findings of various genetic and biochemical studies indicate that this species is heterogeneous. The increasing number of isolated ...
CNS Toxicity
... disturbances and intellectual impairment Histology: gliosis and loss of neurons in basal ganglia ...
... disturbances and intellectual impairment Histology: gliosis and loss of neurons in basal ganglia ...
CNSToxicity
... disturbances and intellectual impairment Histology: gliosis and loss of neurons in basal ganglia ...
... disturbances and intellectual impairment Histology: gliosis and loss of neurons in basal ganglia ...
Phenol and Its Toxicity: A Case Report
... may also be present in urine at concentrations of 20-200 mg/ml, mainly in the conjugated form. Endogenous phenol concentration in urine is about 5-10 mg/ml on average [3]. There are many reports on toxic injuries with phenols including cases with fatal outcome [1, 7, 8]. Intense burning of the mouth ...
... may also be present in urine at concentrations of 20-200 mg/ml, mainly in the conjugated form. Endogenous phenol concentration in urine is about 5-10 mg/ml on average [3]. There are many reports on toxic injuries with phenols including cases with fatal outcome [1, 7, 8]. Intense burning of the mouth ...
Detection of marine toxins using cell-based assays and
... resulting in high biomass which can cause hypoxia or anoxia and may cause mortality of marine fauna after reaching high densities, ii) HAB species that may proliferate and their high densities may cause physical damage, for example to fish gills or also to man-made structures such as water filtering ...
... resulting in high biomass which can cause hypoxia or anoxia and may cause mortality of marine fauna after reaching high densities, ii) HAB species that may proliferate and their high densities may cause physical damage, for example to fish gills or also to man-made structures such as water filtering ...
Full Text - J
... CrTX-A was the first toxin isolated that was determined to be the causative agent of cutaneous inflammation due to jellyfish stings. Proteinaceous Toxins from C. alata The box jellyfish (sea wasp) C. alata is a stinging jellyfish.6) Stinging by C. alata causes cutaneous pain and inflammation in huma ...
... CrTX-A was the first toxin isolated that was determined to be the causative agent of cutaneous inflammation due to jellyfish stings. Proteinaceous Toxins from C. alata The box jellyfish (sea wasp) C. alata is a stinging jellyfish.6) Stinging by C. alata causes cutaneous pain and inflammation in huma ...
Chapter 164 - Plants, Mushrooms, and Herbal Medications
... (e.g., bradycardia and hypotension) and gastrointestinal (e.g., nausea, vomiting, and abdominal pain) effects. Although ingestion of a few leaves is unlikely to cause symptoms, larger exposures can cause severe toxicity. In addition, these plant toxins can be concentrated in honey, so large honey in ...
... (e.g., bradycardia and hypotension) and gastrointestinal (e.g., nausea, vomiting, and abdominal pain) effects. Although ingestion of a few leaves is unlikely to cause symptoms, larger exposures can cause severe toxicity. In addition, these plant toxins can be concentrated in honey, so large honey in ...
Pyrethroids
... the symptoms: bringing down fever, preventing seizures, etc. Atropine will decrease the amount of saliva produced, but is not particularly effective against other symptoms. Ecotoxicology Pyrethroids are extremely toxic to fish and should not be used in locations or under conditions that result in th ...
... the symptoms: bringing down fever, preventing seizures, etc. Atropine will decrease the amount of saliva produced, but is not particularly effective against other symptoms. Ecotoxicology Pyrethroids are extremely toxic to fish and should not be used in locations or under conditions that result in th ...
ICD-9 272.7 Chemically induced lipidosis. 293.83 Mood Disorder
... allergic arthritis NOS (716.2) 713.7 Other general diseases with articular involvement Code first underlying disease, as: amyloidosis (277.3); familial Mediterranean fever (277.3); sarcoidosis (135) 713.8 Arthropathy associated with other conditions classifiable elsewhere 796.0 Symptomatic drug toxi ...
... allergic arthritis NOS (716.2) 713.7 Other general diseases with articular involvement Code first underlying disease, as: amyloidosis (277.3); familial Mediterranean fever (277.3); sarcoidosis (135) 713.8 Arthropathy associated with other conditions classifiable elsewhere 796.0 Symptomatic drug toxi ...
Sequestered defensive toxins in tetrapod vertebrates: principles
... several species of Taricha, including identification of the key mutations in the molecular target of TTX, the voltagegated sodium channels of cellular membranes (Feldman et al. 2009). The best studied of these interactions, between Thamnophis sirtalis and Taricha granulosa, includes extensive geogra ...
... several species of Taricha, including identification of the key mutations in the molecular target of TTX, the voltagegated sodium channels of cellular membranes (Feldman et al. 2009). The best studied of these interactions, between Thamnophis sirtalis and Taricha granulosa, includes extensive geogra ...
Tn917 insertion site in the 2C4 mutant
... Killing efficiency depends on bacterial cell density, the bacterial strain, & the age of the nematode Toxicity can be inactivated by autoclaving the plate Toxicity does not required direct bacteria to worm contact; The toxin is diffusible. The toxin decreases worm mobility. Most worms die wit ...
... Killing efficiency depends on bacterial cell density, the bacterial strain, & the age of the nematode Toxicity can be inactivated by autoclaving the plate Toxicity does not required direct bacteria to worm contact; The toxin is diffusible. The toxin decreases worm mobility. Most worms die wit ...
PESTICIDE TOXICITY
... Chronic toxicity can also affect the reproductive system, nervous system, liver, and kidneys. Cholinesterase Inhibition One of the most widely occurring types of chronic toxicity is cholinesterase inhibition. Cholinesterase is an enzyme produced by the body that controls nerve impulse transmission. ...
... Chronic toxicity can also affect the reproductive system, nervous system, liver, and kidneys. Cholinesterase Inhibition One of the most widely occurring types of chronic toxicity is cholinesterase inhibition. Cholinesterase is an enzyme produced by the body that controls nerve impulse transmission. ...
Biomarkery a mechanismy toxicity
... reacting with „nucleophiles“ in cells – i.e. electrone-rich sites (nucleotides, -NH2, -SH and others) 4) Only certain specific compounds selectively affect specific targets causing „specific“ toxicity (enzyme inhibitions – e.g. drugs, insecticides; receptor interactions – e.g. estrogens; effects at ...
... reacting with „nucleophiles“ in cells – i.e. electrone-rich sites (nucleotides, -NH2, -SH and others) 4) Only certain specific compounds selectively affect specific targets causing „specific“ toxicity (enzyme inhibitions – e.g. drugs, insecticides; receptor interactions – e.g. estrogens; effects at ...
poisoning - Cecchini Cuore
... sweating occurs in moderately severe poisoning. • Petechiae &subconjunctival haemorrhages can occur due to reduced platelet aggregation but this is self-limiting. • Signs of serious poisoning include metabolic acidosis, renal failure & CNS effects as agitation, confusion, coma& fits. • Rarely, pulmo ...
... sweating occurs in moderately severe poisoning. • Petechiae &subconjunctival haemorrhages can occur due to reduced platelet aggregation but this is self-limiting. • Signs of serious poisoning include metabolic acidosis, renal failure & CNS effects as agitation, confusion, coma& fits. • Rarely, pulmo ...
Eye-specific Segregation Requires Neural Activity in Three
... The segregation of afferent fiber projections from two or more sources into patches, columns, or bands occurs widely in the vertebrate central nervous system. The mechanisms which mediate this segregation are not yet understood; however, several investigators have proposed that segregation might be ...
... The segregation of afferent fiber projections from two or more sources into patches, columns, or bands occurs widely in the vertebrate central nervous system. The mechanisms which mediate this segregation are not yet understood; however, several investigators have proposed that segregation might be ...
Supplementary Information (doc 88K)
... and a TBS-380 Fluorometer (Turner Biosystems, CA, USA). A sample of double-stranded DNA, 9.6 million molecules/ml, with an average size of 625 bp were combined with 9.6 million DNA capture beads, and then amplified by emulsion PCR. After bead recovery and bead enrichment, the bead attached DNAs were ...
... and a TBS-380 Fluorometer (Turner Biosystems, CA, USA). A sample of double-stranded DNA, 9.6 million molecules/ml, with an average size of 625 bp were combined with 9.6 million DNA capture beads, and then amplified by emulsion PCR. After bead recovery and bead enrichment, the bead attached DNAs were ...
Appendix B: Provincial Case Definitions for Reportable Diseases
... A diagnosis of PSP should be based on clinically compatible signs and symptoms, in the context of a history of recent shellfish/seafood consumption. Confirmation of the diagnosis can be made by detection of the biotoxin (i.e., saxitoxin, or its analogues) at concentrations sufficient to cause sympto ...
... A diagnosis of PSP should be based on clinically compatible signs and symptoms, in the context of a history of recent shellfish/seafood consumption. Confirmation of the diagnosis can be made by detection of the biotoxin (i.e., saxitoxin, or its analogues) at concentrations sufficient to cause sympto ...
Tetrodotoxin
Tetrodotoxin, frequently abbreviated as TTX, is a potent neurotoxin. Its name derives from Tetraodontiformes, an order that includes pufferfish, porcupinefish, ocean sunfish or mola, and triggerfish; several species that carry the toxin. Although tetrodotoxin was discovered in these fish and found in several other animals (e.g., blue-ringed octopus, rough-skinned newt, and Naticidae) it is actually produced by certain symbiotic bacteria, such as Pseudoalteromonas tetraodonis, certain species of Pseudomonas and Vibrio, as well as some others that reside within these animals.Tetrodotoxin inhibits the firing of action potentials in nerves by binding to the voltage-gated sodium channels in nerve cell membranes and blocking the passage of sodium ions (responsible for the rising phase of an action potential) into the nerve cell.Its mechanism of action, selective blocking of the sodium channel, was shown definitively in 1964 by Toshio Narahashi and professor John W. Moore at Duke University, using the sucrose gap voltage clamp technique.