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Chapter 10 Review Crossword Across 1. Examples of _________ hazards include fires, earthquakes, and floods 4. A chemical that has a median lethal dose of 50 mg or less per kg of body weight 5. The amount of a chemical that kills exactly 50% of a test population 7. Human-made chemicals that can mimic and disrupt the effect of natural hormones 9. The process in which levels of a toxin are magnified as the pass through the food chain 10. The study of how toxins affect living organisms 11. Powerful pesticide that is partly responsible for reducing malaria, but also bioaccumulates and thins the shells of various birds 14. The amount of damage that result from exposure to a chemical Down 2. Examples of _________ hazards include smoking, poor diet, and criminal assault 3. The process in which substances are absorbed and stored in organs or tissues at higher than normal levels 6. The possibility of suffering harm from a hazard that can cause injury, disease, economic loss, or environmental damage 8. Examples of _________ hazards include viruses, pollen, and snake bites 11. The amount of a substance a person has ingested, inhaled, or absorbed 12. Examples of _________ hazards include mercury in food, arsenic in water, and carbon monoxide in the air 13. A mathematical statement about the likelihood of harm (ex: the odds of dying from a snake bite are 1 in 56 million) Question 1. Define risk. 2. List and give an example of the 4 types of hazards people face. Answer The possibility of suffering harm from a hazard 1. Cultural- smoking, drinking, driving, etc. 2. Chemical- air, water, food, soil 3. Physical- fires, floors, earthquakes, etc. 4. Biological- pathogens, pollens, allergens, animals 3. Do all chemicals affect people the same way (explain using the dose response curve)? No, some individuals are more or less affected by any given dose. 4. What factors affect the response an individual has to a chemical? 5. List 3 ways a harmful substance can enter a person. Age, gender, genes, immune system 6. Define dose. How much of a substance a person inhales, ingests or absorbs Water soluble chemicals can be flushed out of the body. Fat soluble chemicals are more dangerous b/c they get stored in fat tissue and cannot be removed. chemicals stored in organs (fat) of animals 7. Differentiate between water and fat soluble chemicals. 8. Define bioaccumulation. 9. Define biomagnifications. 10. Explain why some chemicals are found in large amounts at the top of a food chain? 11. Differentiate between antagonistic and synergistic interactions. 1. inhalation 2. ingestion 3. absorption Chemicals are passed to each member of the food chain. Animals at the top of the chain have the highest concentration of chemicals in their system Levels of a toxin are magnified at each trophic level Antagonistic- reduces harmful effects Synergistic- multiplies harmful effects 12. List 3 ways studies are used to estimate toxicity. 13. Define poison. 14. What does “the dose makes the poison” mean? 15. What is a mutagen? Give an example. 16. What is a teratogen? Give an example. 17. What is a carcinogen? Give an example. 18. What systems are compromised by toxic chemicals in the environment? 19. Differentiate between transmissible and non transmissible diseases. 20. What is a pathogen? 21. Differentiate between risk assessment and risk management. 22. Why are antibiotics ineffective against viruses? 23. Describe how bacteria become resistant to antibiotics? 24. What are HAA? 25. What is meant by pollution prevention? 1. case reports 2. epidemiological studies 3. lab experiments Chemical that has a lethal does of 50 mg/kg of body weight Any substance is harmful is the dose is high enough Causes changes to DNA. X-rays, UV rays, sudan IV, ethidium bromide Causes damage to an embryo/fetus. Drugs, alcohol, medications Causes tumors/cancer. Cigarette smoke, asbestos, radiation, certain chemicals Immune, nervous, endocrine Transmissible- caused by living organisms and can spread from person to person. (bacteria, virus, parasite) Nontransmissible- caused by something other than a living organism and does not spread from person to person. (cancer, diabetes, etc.) A living organism that causes disease. Assessment- estimation harmful effects Management- reducing/eliminating risk If antibiotics are used too often for things they can't treat—like colds or other viral infections—they can stop working effectively against bacteria and lead to resistance. Increased exposure to antibiotics leads to genetic changes in bacteria. Hormonally active agents- synthetic chemicals that alter hormone levels. Stopping pollution from happening rather than cleaning it up.