Download Wednesday April 26 - Centre for Molecular Biology and Neuroscience

Gaustad Neuroscience Network (GNN)
CMBN and GNN minisymposium February 4-5, 2008:
Biology of Aging and Neurodegeneration –
Focus on Genome Dynamics
Venue:
February 4 - Seminar room B1.1017 and
February 5 - Auditorium 1 Green, Rikshospitalet, Oslo, Norway
Sign up before January 31 to Helene Wold Ranum at [email protected]
All talks are 15 min + 5 min discussion. The program might be subject to small adjustments.
Monday February 4
9:00 Welcome – Tone Tønjum, CMBN and University of Oslo
9:05 Vilhelm A. Bohr, Laboratory of Molecular gerontology, National Inst. on Aging (NIA),
National Institutes of Health (NIH), US
DNA Repair, premature aging and neurodegeneration
9:30 Tinna Stevnsner, University of Århus, Denmark
Aging aspects of mitochondrial repair
9:50 Coffee
10:15 Arne Klungland/Line Nordstrand, CMBN:
Distinct roles of the ALkB family of dioxygenases for demethylating DNA, RNA and protein
10:35 Magnar Bjørås, CMBN
Base excision repair of oxidative DNA damage
10:55 Ingrun Alseth, CMBN:
Functional characterisation of genetic alterations in DNA glycosylase genes in
patients with primary sclerosing cholangitis and cholangiocarsinoma
11:15 Tone Tønjum / Tonje Davidsen, CMBN
Genome dynamics in CNS pathogenesis
12:00-13:00 Lunch
13:00 Ole Petter Ottersen, CMBN
Maintaining brain water homeostasis
13:20
Mahmood Amiry-Moghaddam, CMBN
Mechanisms governing expression of AQP4
13:40 Elise Rundèn-Pran, CMBN:
DNA repair in relation to ischemic brain damage
14:00 Farrukh A. Chaudhry, Biotechnology Center of Oslo and CMBN
Functional roles of amino acid transporters in neuronal signaling
14:20 Coffee
14:40 Thomas Espeseth/Ivar Reinvang, Department of Psychology, University of Oslo:
Neurogenetics of brain structure and function in aging
15:00 Trygve Leergaard / Jan Bjaalie, CMBN: Localization of function: multimodality
imaging and atlasing in rat brain under health and disease
15:30 Meet the speaker – graduate students and postdocs
16:30 Pizza and beverages at Rikshospitalet
Tuesday February 5
9:00 Introduction – Vilhelm A. Bohr, NIA/NIH
9:05 David Wilson III, NIA, NIH
Roles of core and auxiliary base excision DNA repair proteins
9:25 Yie Liu, NIA, NIH
The role of BER in telomere maintenance in vivo
9:45 Alexander D. Rowe /Torbjørn Rognes, CMBN: The role of FEN1 in CAG-repeat
expansion in transgenic Huntington mice
10:05 Coffee break
10:30 Herman Ambur, CMBN: DNA signatures in evolution: News on DUS
10:50 Stephan A. Frye, CMBN: Compensation for genetic isolation in Mycobacterium
tuberculosis
11:20 Vidar Gundersen, CMBN and Rikshospitalet:
Drugs affecting glutamate signalling in clinical neurology
12:00–13:00 Lunch
13:00 Panel discussion – Forefront visions in science & technology
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Burning scientific topics. Open questions?
What are the new technologies, and how do we exploit them?
13:45 Concluding remarks – Vilhelm A. Bohr, Ole Petter Ottersen and Tone Tønjum
14:00 Meeting ends, but the discussions go on…