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Name ____________KEY________________________Date __________ Pd ________ TEST REVIEW - GENETIC PROBLEMS 1. When an organism inherits 2 genes for a trait that are the same, this is termed ____homozygous_________. 2. The physical appearance of an organism is called the ___phenotype___. 3. Which of Mendel’s laws states that gene pairs separate when gametes are formed? __law__ of __segregation______. 4. Segments of DNA that control a trait are called ____genes___. 5. The genetic makeup of an organism is called its __genotype_________. 6. When an organism inherits one dominant gene & one recessive gene for a trait, this is termed ____heterozygous__________. 7. A trait controlled by 3 or more alleles is called _multiple allele____________. 8. Another word for heterozygous is hybrid____. 9. The study of heredity is called genetics 10. Give an example of a trait in humans that is determined by multiple alleles: ____hair color___ 11. Fill in the blanks in the table below, specifying which antigen and which antibodies are present with each blood type. BLOOD TYPE A B AB O ANTIGEN A B A,B NONE ANTIBODY B A NONE A,B 12. Fill in the blanks in the table below on transfusions. BLOOD TYPE A B AB O CAN RECEIVE A,O B,O A,B,AB,O O 13. What determines blood type? ANTIGEN 14. Which blood type is the universal donor? _O___ CAN BE GIVEN TO A B AB A,B,AB,O 15. Which type is the universal recipient? ___AB_____ 16. The genotypes for a person with blood type A are __iAiA__ & iAi 17. The genotype for a person with blood type O is __ii_____; the genotype for a person with blood type AB is __ iAiB________. 18. The genotypes for a person with blood type B are __ iBiB ____________ & ____ iBi ___________. 19. A man who is homozygous for blood type A marries a woman with blood type O. What blood types are possible in this couple’s children? ______ iAiA x ii_______________________________ (Equation) iAi gr _________DO NOT DO__________________________________ A i i iAi pr __________100% A type blood__________________________________ iAi 20. A man with blood type B, whose mother was blood type O, marries a woman with blood type AB. What blood types are possible in this couple’s children? _____iBi x iAiB________________________ (Equation) B i i iA iB iAiB iAi iB iB iB i gr ____________Do not do pr ________50% B, 25% AB, 25% A_____________________________ Polygenic Traits 21. The inheritance pattern of a trait controlled by many (2 or more genes) with a wide range of possible traits in the offspring is __polygenic_______________. 22. List 3 traits in humans that are controlled by polygenic inheritance: height, hair color, eye color 23. In Dinosaurs, height is controlled by more than one pair of genes. We can symbolize the genes as A, B, C, D, & E. Brachiosaurus is homozygous dominant for every gene and was 17 meters tall. The smallest dinosaur was 2 meters tall. Answer the following questions. a. How many meters does each dominant allele add to the height of a dinosaur? 17-2=15/10=1.5 meters for every dominant allele b. How tall are each of the following dinosaurs: T-rex: AABBCCDdEe- 14 meters Triceratops: AABbccddee- 6.5 meters 24. In plants, height is controlled by more than one pair of genes. We can symbolize the genes as L, M, & N. A plant of intermediate height (10 cm) would have 3 dominant & 3 recessive alleles, and may be written as LlMmNn, llMMNn or any combination thereof. Each extra dominant allele adds 2 cm to the total height of the plant. a. Write the genotype of a plant that is 14 cm tall. LLMMNn b. Write the genotype of a plant that is 6 cm tall Llmmnn Sex-linked 25. Traits that are determined by genes on the sex chromosomes are called ___X-linked or sex linked____ traits. The chromosome that the genes are usually found on is the ___X chromosome_________. 26. The 23rd pair of chromosomes that differ in males & females are called ____sex chromosomes_______. 27. The sex chromosomes for a male are __XY_;The sex chromosomes for a female are __XX___. 28. Why are more males born with hemophilia or any sex-linked trait? They only have one X chromosome so only need one recessive allele to have the trait. 29. Since color-blindness is carried on the X chromosome, a mother who is a carrier can pass the gene to: a. All of her daughters b. 50 % of her daughters c. All of her sons d. 50 % of her sons e. Both b & d 30. A color-blind father cannot pass the color-blind gene to: a. his daughters b. his sons c. any of his children 31. What are the genotypes of the following: Man with hemophilia: _XhY_____ Carrier Female: __XHXh______ Normal Male: _XHY____ Normal Female: __XHXH___ Female with hemophilia: ___XhXh_____ 32. Hemophilia is a blood disorder that prevents clotting. It is a recessive, sex-linked trait. If the mother is a completely healthy for the disease and the father is a hemophiliac, complete the following questions: a. Cross them and show their punnett square. ______ XHXH x XhY ______________ (Equation) H X gr ______Do not do_____________ XH Xh XHXh XHXh XHY XHY pr _____do not do____________________ Y b. What is the probability that the child will NOT have hemophilia? 100%_ c. What is the probability that a child will be affected? 0%_ 33. One form of colorblindness in humans is caused by a sex-linked recessive gene. A woman with normal color vision and whose father was color blind marries a man of normal vision whose father was also color blind. ____ XHXh x XHY_____________________ (Equation) XH XH Xh XHXH XHXh gr ___Do not do____________ Y XHY XhY pr __Do not do________________________ a. What proportion of their offspring will be color blind? (give your answer separately for males and females) ____Females- 0%, Males- 50%_______________________________ Pedigrees 34. Fill out the Chart Symbol Meaning Normal female Normal male Affected female Affected male Normal female Normal male Married couple Answer the following questions about the sex-linked pedigree. The sex-linked trait is Hemophilia. 35. Is this trait dominant or recessive? ___recessive_____ 36. How many males have the trait? _3_ 37. How many females have the trait? _2__ 38. List the genotypes of each individual in the pedigree. Remember this trait is sex-linked! Individual Genotype I-1 I-2 II-1 II-2 II-3 III-1 XHY XhXh XHXh XHXh XHY XHY III-2 III-3 III-4 IV-1 IV-2 IV-3 XHX? XhY XHXh XhY XHXh XhY IV-4 IV-5 IV-6 IV-7 XhXh XHY XHY XHXh 39. Is the trait dominant or recessive? ___Recessive__ Individual Genotype I-1 XnXn XNX? I-2 II-1 XNXn II-2 XNXn II-3 XNXn II-4 XNX? III-1 XNXn III-2 XNXn III-3 XNX? IV-1 XnXn IV-2 XNX? IV-3 XnXn IV-4 XNX? 40. Write the genotype for each individual (use a letter of your choice) 41. How is individual II-3(male) related to the individual IV-1(female)? Father and daughter