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Supplementary Table 2. Summary of the fifty-seven gene-function correlated schizophrenia
susceptibility genes in context of thalamic neurons. “+” in “association result”: positive finding of at
least one SNP in at least one association study attempted for the target gene. “+” in “qPCR result”: pvalue < 0.05 by Welch test. NA: not assayed.
Chromosome Gene
Symbol
ADSS
1
Locus
ID
159
Protein Name
Association
Result
qPCR
Result
adenylosuccinate synthase
-
NA
1
ASTN1
460
astrotactin
+
-
1
GCLM
2730
glutamate-cysteine ligase regulatory protein
+
-
1
TSNAX
7257
translin-associated factor X
+
-
2
ACP1
52
acid phosphatase 1
-
NA
2
CTNNA2
1496
catenin, alpha 2
+
+
2
GLS
2744
glutaminase C
-
NA
2
INPP1
3628
inositol polyphosphate-1-phosphatase
-
NA
2
IRS1
3667
insulin receptor substrate 1
-
NA
2
PPP3R1
5534
protein phosphatase 3, regulatory subunit B, alpha
isoform 1
-
NA
2
SLC25A12
8604
solute carrier family 25 (mitochondrial carrier,
Aralar), member 12
-
NA
3
CHL1
10752
cell adhesion molecule with homology to L1CAM
+
+
3
GAP43
2596
growth associated protein 43
-
NA
3
MAP4
4134
microtubule-associated protein 4
+
-
3
PIK3CB
5291
phosphoinositide-3-kinase, catalytic, beta
polypeptide
-
NA
4
PDLIM5
10611
PDZ and LIM domain 5
+
NA
5
CANX
821
calnexin
-
NA
5
CARTPT
9607
cocaine- and amphetamine-regulated transcript
-
NA
5
KIF2A
3796
kinesin heavy chain member 2
-
NA
5
NR3C1
2908
nuclear receptor subfamily 3, group C, member 1
-
NA
5
PPP2R2B
5521
beta isoform of regulatory subunit B55, protein
phosphatase 2
-
NA
5
RAPGEF6
51735
6
C4A/C4B
6
SLC25A27
9481
6
TCP1
8
PDZ domain-containing guanine nucleotide
exchange factor I
+
-
+
+
solute carrier family 25, member 27
+
+
6950
T-complex protein 1
+
+
FZD3
7976
frizzled 3
+
NA
8
NEFL
4747
neurofilament, light polypeptide 68kDa
-
NA
8
NEFM
4741
neurofilament 3
-
NA
8
PCM1
5108
pericentriolar material 1
+
-
8
PPP3CC
5533
protein phosphatase 3 (formerly 2B), catalytic
subunit, gamma isoform (calcineurin A gamma)
+
NA
9
SLC1A1
6505
solute carrier family 1, member 1
-
NA
9
SMARCA2
6595
SWI/SNF-related matrix-associated actindependent regulator of chromatin a2
-
NA
10
BLOC1S2
282991
biogenesis of lysosome-related organelles complex1, subunit 2
-
NA
10
INPP5A
3632
inositol polyphosphate-5-phosphatase A
-
NA
10
NRG3
10718
neuregulin 3
+
-
10
PGAM1
5223
phosphoglycerate mutase 1 (brain)
-
NA
10
SLC18A2
6571
solute carrier family 18 (vesicular monoamine),
member 2
+
+
11
GRIA4
2893
glutamate receptor, ionotrophic, AMPA 4
+
-
12
CNTN1
1272
contactin 1
-
NA
13
ESD
2098
esterase D/formylglutathione hydrolase
+
+
13
FGF14
2259
fibroblast growth factor 14
+
NA
14
DAAM1
23002
dishevelled-associated activator of morphogenesis
1
-
NA
14
EIF2B2
8892
eukaryotic translation initiation factor 2B, subunit 2
beta, 39kDa
-
NA
15
NTRK3
4916
neurotrophic tyrosine kinase, receptor, type 3
+
-
720/721 complement component 4A/4B
15
PLDN
26258
pallidin
-
NA
16
HP
3240
haptoglobin
+
NA
17
PAFAH1B1
5048
platelet-activating factor acetylhydrolase, isoform
Ib, alpha subunit
-
NA
18
ADCYAP1
116
adenylate cyclase activating polypeptide
+
-
18
GNAL
2774
guanine nucleotide binding protein (G protein),
alpha activating activity polypeptide, olfactory type
+
-
20
CHGB
1114
chromogranin B
+
+
20
DPM1
8813
dolichyl-phosphate mannosyltransferase
polypeptide 1
-
NA
20
PRNP
5621
prion protein
-
NA
21
SYNJ1
8867
synaptojanin 1
-
NA
22
ST13
6767
heat shock 70kD protein binding protein
-
NA
22
UBE2L3
7332
ubiquitin-conjugating enzyme E2L 3
-
NA
23
SLC25A14
9016
solute carrier family 25, member 14
-
NA
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