Download 老年人生活质量ESI高被引论文80篇、热点论文1篇

老年人生活质量 ESI 高被引论文 80 篇、热点论文 1 篇
热点论文 1 篇（第 5 篇）
第 1 条，共 81 条
标题: The effects of Pilates exercise training on physical fitness and wellbeing in the elderly: A
systematic review for future exercise prescription
作者: Bullo, V (Bullo, V.); Bergamin, M (Bergamin, M.); Gobbo, S (Gobbo, S.); Sieverdes, JC
(Sieverdes, J. C.); Zaccaria, M (Zaccaria, M.); Neunhaeuserer, D (Neunhaeuserer, D.); Ermolao, A
(Ermolao, A.)
来源出版物: PREVENTIVE MEDICINE 卷: 75 页: 1-11 DOI: 10.1016/j.ypmed.2015.03.002
出版年: JUN 2015
Web of Science 核心合集中的 "被引频次": 8
被引频次合计: 9
引用的参考文献数: 40
摘要: This systematic review aims to summarize the effects of Pilates exercise training (PET) in
elderly population on physical fitness, balance and fall prevention, and its effects on mood states,
quality of life and independence in the daily living activities.
Methods. Keyword "Pilates" associated with "elderly", "aging" and "old subjects" were identified
as terms for the literature research in MEDLINE, Embase, PubMed, Scopus, PsycINFO and
SPORTDiscus. Only studies published in peer-reviewed journals written in English language were
considered. A meta-analysis was performed and effect sizes (ES) calculated.
Results. 10 studies were identified (6 RCTs and 4 uncontrolled trials); age ranged from 60 to 80
years. Overall, PET showed large ES to improve muscle strength (ES = 1.23), walking and gait
performances (ES = 1.39), activities of daily living, mood states and quality of life (ES = 0.94),
moderate to high effect on dynamic balance (ES = 0.77), small effects on static balance (ES =
0.34) and flexibility (ES = 0.31), while a small effect on cardiometabolic outcomes (ES = 0.07).
Conclusions. PET should be taken into account as a way to improve quality of life in the elderly,
due to the imparted benefits of fall prevention, physical fitness, and mood states. In this context,
physicians might include PET as a tool for exercise prescriptions for the elderly. (C) 2015 Elsevier
Inc. All rights reserved.
文献类型: Review
作者关键词: Elderly; Pilates; Physical fitness; Fall prevention; Review
KeyWords Plus: OLDER-ADULTS; BALANCE; STRENGTH; PROGRAM; HEALTH;
WOMEN; OSTEOARTHRITIS; PERFORMANCE; MORTALITY
地址: [Bullo, V.; Bergamin, M.; Gobbo, S.; Zaccaria, M.; Neunhaeuserer, D.; Ermolao, A.] Univ
Padua, Dept Med, Sport & Exercise Med Div, Padua, Italy.
[Sieverdes, J. C.] Med Univ S Carolina, Coll Nursing, Technol Applicat Ctr Healthful Lifestyles,
Charleston, SC USA.
通讯作者地址: Bergamin, M (通讯作者),Univ Padua, Dept Med, Sport & Exercise Med Div,
Padua, Italy.
电子邮件地址: [email protected]
来源出版物页码计数: 11
第 2 条，共 81 条
标题: Tango for treatment of motor and non-motor manifestations in Parkinson's disease: A
randomized control study
作者: Romenets, SR (Romenets, Silvia Rios); Anang, J (Anang, Julius); Fereshtehnejad, SM
(Fereshtehnejad, Seyed-Mohammad); Pelletier, A (Pelletier, Amelie); Postuma, R (Postuma,
Ronald)
来源出版物: COMPLEMENTARY THERAPIES IN MEDICINE 卷: 23 期: 2 页: 175-184
DOI: 10.1016/j.ctim.2015.01.015 出版年: APR 2015
Web of Science 核心合集中的 "被引频次": 8
被引频次合计: 8
引用的参考文献数: 55
摘要: Objective: To determine effects of Argentine tango on motor and non-motor manifestations
of Parkinson's disease.
Design: Randomized control trial.
Participants: Forty patients with idiopathic Parkinson's disease.
Setting: Movement disorder clinic and dance studio.
Intervention: Two randomized groups: group (N = 18) with 24 partnered tango classes, and control
self-directed exercise group (N = 15).
Main outcomes measures: The primary outcome was overall motor severity. Secondary outcomes
included other motor measures, balance, cognition, fatigue, apathy, depression and quality of life.
Results: On the primary intention-to-treat analysis there was no difference in motor severity
between groups MDS-UPDRS-3 (1.6 vs.1.2-point reduction, p=0.85). Patient-rated clinical global
impression of change did not differ (p = 0.33), however examiner rating improved in favor of
tango (p = 0.02). Mini-BESTest improved in the tango group compared to controls (-0.7 +/- 2.2 vs.
-2.7 +/- 5.9, p = 0.032). Among individual items, tango improved in both simple TUG time (-1.3
+/- 1.6 s vs. -0.1 +/- 2.3, p = 0.042) and TUG Dual Task score (-0.4 +/- 0.9 vs. -0.2 +/- 0.4, p =
0.012), with borderline improvement in walk with pivot turns (-0.2 +/- 0.5 vs. -0.1 +/- 0.5, p =
0.066). MoCa (0.4 +/- 1.6 vs. -0.6 +/- 1.5, p = 0.080) and FSS (-3.6 +/- 10.5 vs. 2.5 +/- 6.2, p =
0.057) showed a non-significant trend toward improvement in the tango group. Tango participants
found the activity more enjoyable (p < 0.001) and felt more "overall" treatment satisfaction (p <
0.001). We found no significant differences in other outcomes or adverse events.
Conclusion: Argentine tango can improve balance, and functional mobility, and may have modest
benefits upon cognition and fatigue in Parkinson's disease. These findings must be confirmed in
longer-term trials explicitly powered for cognition and fatigue. (C) 2015 Elsevier Ltd. All rights
reserved.
文献类型: Article
作者关键词: Parkinson's disease; Dance therapy; Argentine tango; Treatment
KeyWords Plus: MONTREAL COGNITIVE ASSESSMENT; QUALITY-OF-LIFE;
ARGENTINE TANGO; POSTURAL STABILITY; PHYSICAL-ACTIVITY; SOCIAL
DANCERS; MENTAL FATIGUE; MINI-BESTEST; OLDER-ADULTS; BALANCE
地址: [Romenets, Silvia Rios; Anang, Julius; Pelletier, Amelie; Postuma, Ronald] McGill Univ,
Montreal Gen Hosp, Dept Neurol, Montreal, PQ H3G 1A4, Canada.
[Fereshtehnejad, Seyed-Mohammad] Karolinska Inst, Div Clin Geriatr, Dept Neurobiol, Care Sci
& Soc NVS, Stockholm, Sweden.
通讯作者地址: Postuma, R (通讯作者),Montreal Gen Hosp, Dept Neurol, L7-312,1650 Cedar
Ave, Montreal, PQ H3G 1A4, Canada.
电子邮件地址: [email protected]
来源出版物页码计数: 10
第 3 条，共 81 条
标题: Current evidence on risk factors for knee osteoarthritis in older adults: a systematic review
and meta-analysis
作者: Silverwood, V (Silverwood, V.); Blagojevic-Bucknall, M (Blagojevic-Bucknall, M.); Jinks,
C (Jinks, C.); Jordan, JL (Jordan, J. L.); Protheroe, J (Protheroe, J.); Jordan, KP (Jordan, K. P.)
来 源 出 版 物 : OSTEOARTHRITIS AND CARTILAGE 卷 : 23 期 : 4 页 : 507-515 DOI:
10.1016/j.joca.2014.11.019 出版年: APR 2015
Web of Science 核心合集中的 "被引频次": 11
被引频次合计: 12
引用的参考文献数: 63
摘要: Osteoarthritis (OA) is a leading cause of pain and disability and leads to a reduced quality
of life. The aim was to determine the current evidence on risk factors for onset of knee pain/OA in
those aged 50 and over. A systematic review and meta-analysis was conducted of cohort studies
for risk factors for the onset of knee pain. Two authors screened abstracts and papers and
completed data extraction. Where possible, pooled odds ratios (OR) were calculated via random
effects meta-analysis and population attributable fractions (PAFs) derived. 6554 papers were
identified and after screening 46 studies were included. The main factors associated with onset of
knee pain were being overweight (pooled OR 1.98, 95% confidence intervals (CI) 1.57-2.20),
obesity (pooled OR 2.66 95% CI 2.15-3.28), female gender (pooled OR 1.68, 95% CI 1.37-2.07),
previous knee injury (pooled OR 2.83, 95% CI 1.91-4.19). Hand OA (pooled OR 1.30, 95% CI
0.90-1.87) was found to be non-significant. Smoking was found not to be a statistically significant
risk or protective factor (pooled OR 0.92, 95% CI 0.83-1.01). PAFs indicated that in patients with
new onset of knee pain 5.1% of cases were due to previous knee injury and 24.6% related to being
overweight or obese. Clinicians can use the identified risk factors to identify and manage patients
at risk of developing or increasing knee pain. Obesity in particular needs to be a major target for
prevention of development of knee pain. More research is needed into a number of potential risk
factors. (C) 2014 The Authors. Published by Elsevier Ltd and Osteoarthritis Research Society
International.
文献类型: Review
作 者 关 键 词 : Osteoarthritis; Knee; Incidence/onset; Risk factors; Systematic review;
Meta-analysis
KeyWords Plus: BODY-MASS INDEX; MIDDLE-AGED WOMEN; GENERAL-POPULATION;
PHYSICAL-ACTIVITY; HIP OSTEOARTHRITIS; FOLLOW-UP; MUSCULOSKELETAL
CONDITIONS;
CLEARWATER
OSTEOARTHRITIS;
PROSPECTIVE
COHORT;
SUBSEQUENT KNEE
地址: [Silverwood, V.; Blagojevic-Bucknall, M.; Jinks, C.; Jordan, J. L.; Protheroe, J.; Jordan, K.
P.] Keele Univ, Arthritis Res UK Primary Care Ctr, Primary Care Sci, Keele ST5 5BG, Staffs,
England.
通讯作者地址: Silverwood, V (通讯作者),Keele Univ, Arthritis Res UK Primary Care Ctr,
Primary Care Sci, Keele ST5 5BG, Staffs, England.
来源出版物页码计数: 9
第 4 条，共 81 条
标题: Computerized and Virtual Reality Cognitive Training for Individuals at High Risk of
Cognitive Decline: Systematic Review of the Literature
作者: Coyle, H (Coyle, Hannah); Traynor, V (Traynor, Victoria); Solowij, N (Solowij, Nadia)
来源出版物: AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY 卷: 23 期: 4 页:
335-359 DOI: 10.1016/j.jagp.2014.04.009 出版年: APR 2015
Web of Science 核心合集中的 "被引频次": 6
被引频次合计: 6
引用的参考文献数: 86
摘要: The aim of this study was to assess the efficacy of cognitive training, specifically
computerized cognitive training (CCT) and virtual reality cognitive training (VRCT), programs
for individuals living with mild cognitive impairment (MCI) or dementia and therefore at high risk
of cognitive decline. After searching a range of academic databases (CINHAL, PSYCinfo, and
Web of Science), the studies evaluated (N = 16) were categorized as CCT (N = 10), VRCT (N =
3), and multimodal interventions (N = 3). Effect sizes were calculated, but a meta-analysis was not
possible because of the large variability of study design and outcome measures adopted. The
cognitive domains of attention, executive function, and memory (visual and verbal) showed the
most consistent improvements. The positive effects on psychological outcomes (N = 6) were
significant reductions on depressive symptoms (N = 3) and anxiety (N = 2) and improved
perceived use of memory strategy (N = 1). Assessments of activities of daily living demonstrated
no significant improvements (N = 8). Follow-up studies (N = 5) demonstrated long-term
improvements in cognitive and psychological outcomes (N = 3), and the intervention groups
showed a plateau effect of cognitive functioning compared with the cognitive decline experienced
by control groups (N = 2). CCT and VRCT were moderately effective in long-term improvement
of cognition for those at high risk of cognitive decline. Total intervention time did not mediate
efficacy. Future research needs to improve study design by including larger samples, longitudinal
designs, and a greater range of outcome measures, including functional and quality of life
measures, to assess the wider effect of cognitive training on individuals at high risk of cognitive
decline.
文献类型: Article
作者关键词: Systematic review; dementia; mild cognitive impairment; Alzheimer; cognitive
training; computer; virtual reality
KeyWords Plus: RANDOMIZED CONTROLLED-TRIAL; HEALTHY OLDER-ADULTS;
ALZHEIMERS-DISEASE; BRAIN
PLASTICITY; REHABILITATION PROGRAM;
INTERVENTION PROGRAMS; CLINICAL-TRIAL; DOUBLE-BLIND; AGING BRAIN;
IMPAIRMENT
地址: [Coyle, Hannah; Solowij, Nadia] Univ Wollongong, Sch Psychol, Wollongong, NSW 2522,
Australia.
[Traynor, Victoria] Univ Wollongong, Sch Nursing & Midwifery, Wollongong, NSW 2522,
Australia.
通 讯 作 者 地 址 : Traynor, V ( 通 讯 作 者 ),Univ Wollongong, Sch Nursing & Midwifery,
Wollongong, NSW 2522, Australia.
电子邮件地址: [email protected]
来源出版物页码计数: 25
第 5 条，共 81 条
标 题 : Diagnostic and Predictive Accuracy of Blood Pressure Screening Methods With
Consideration of Rescreening Intervals: A Systematic Review for the US Preventive Services Task
Force
作者: Piper, MA (Piper, Margaret A.); Evans, CV (Evans, Corinne V.); Burda, BU (Burda,
Brittany U.); Margolis, KL (Margolis, Karen L.); O'Connor, E (O'Connor, Elizabeth); Whitlock,
EP (Whitlock, Evelyn P.)
来源出版物: ANNALS OF INTERNAL MEDICINE 卷: 162 期: 3 页: 192-U101 DOI:
10.7326/M14-1539 出版年: FEB 3 2015
Web of Science 核心合集中的 "被引频次": 32
被引频次合计: 32
引用的参考文献数: 134
摘要: Background: Elevated blood pressure (BP) is the largest contributing risk factor to all-cause
and cardiovascular mortality.
Purpose: To update a systematic review on the benefits and harms of screening for high BP in
adults and to summarize evidence on rescreening intervals and diagnostic and predictive accuracy
of different BP methods for cardiovascular events.
Data Sources: Selected databases searched through 24 February 2014.
Study Selection: Fair-and good-quality trials and diagnostic accuracy and cohort studies conducted
in adults and published in English.
Data Extraction: One investigator abstracted data, and a second checked for accuracy. Study
quality was dual-reviewed.
Data Synthesis: Ambulatory BP monitoring (ABPM) predicted long-term cardiovascular outcomes
independently of office BP (hazard ratio range, 1.28 to 1.40, in 11 studies). Across 27 studies, 35%
to 95% of persons with an elevated BP at screening remained hypertensive after nonoffice
confirmatory testing. Cardiovascular outcomes in persons who were normotensive after
confirmatory testing (isolated clinic hypertension) were similar to outcomes in those who were
normotensive at screening. In 40 studies, hypertension incidence after rescreening varied
considerably at each yearly interval up to 6 years. Intrastudy comparisons showed at least 2-fold
higher incidence in older adults, those with high-normal BP, overweight and obese persons, and
African Americans.
Limitation: Few diagnostic accuracy studies of office BP methods and protocols in untreated
adults.
Conclusion: Evidence supports ABPM as the reference standard for confirming elevated office BP
screening results to avoid misdiagnosis and overtreatment of persons with isolated clinic
hypertension. Persons with BP in the high-normal range, older persons, those with an
above-normal body mass index, and African Americans are at higher risk for hypertension on
rescreening within 6 years than are persons without these risk factors.
文献类型: Review
KeyWords
Plus:
WHITE-COAT
HYPERTENSION;
10-YEAR
FOLLOW-UP;
QUALITY-OF-LIFE; CARDIOVASCULAR RISK; INCIDENT HYPERTENSION; MASKED
HYPERTENSION; GENERAL-POPULATION; PROGNOSTIC VALUE; SYSTOLIC
HYPERTENSION; TREATED HYPERTENSION
地址: [Piper, Margaret A.; Evans, Corinne V.; Burda, Brittany U.; O'Connor, Elizabeth; Whitlock,
Evelyn P.] Kaiser Permanente Ctr Hlth Res, Portland, OR 97227 USA.
[Margolis, Karen L.] HealthPartners Inst Educ & Res, Minneapolis, MN 55440 USA.
通讯作者地址: Piper, MA (通讯作者),Kaiser Permanente Ctr Hlth Res, 3800 North Interstate
Ave, Portland, OR 97227 USA.
来源出版物页码计数: 27
第 6 条，共 81 条
标题: Can supervised exercise prevent treatment toxicity in patients with prostate cancer initiating
androgen-deprivation therapy: a randomised controlled trial
作者: Cormie, P (Cormie, Prue); Galvao, DA (Galvao, Daniel A.); Spry, N (Spry, Nigel); Joseph,
D (Joseph, David); Chee, R (Chee, Raphael); Taaffe, DR (Taaffe, Dennis R.); Chambers, SK
(Chambers, Suzanne K.); Newton, RU (Newton, Robert U.)
来源出版物: BJU INTERNATIONAL 卷: 115 期: 2 页: 256-266 DOI: 10.1111/bju.12646 出版
年: FEB 2015
Web of Science 核心合集中的 "被引频次": 18
被引频次合计: 18
引用的参考文献数: 50
摘要: Objective
To determine if supervised exercise minimises treatment toxicity in patients with prostate cancer
initiating androgen-deprivation therapy (ADT). This is the first study to date that has investigated
the potential role of exercise in preventing ADT toxicity rather than recovering from established
toxicities.
Patients and Methods
Sixty-three men scheduled to receive ADT were randomly assigned to a 3-month supervised
exercise programme involving aerobic and resistance exercise sessions commenced within 10
days of their first ADT injection (32 men) or usual care (31 men). The primary outcome was body
composition (lean and fat mass). Other study outcomes included bone mineral density, physical
function, blood biomarkers of chronic disease risk and bone turnover, general and prostate
cancer-specific quality of life, fatigue and psychological distress. Outcomes were compared
between groups using analysis of covariance adjusted for baseline values.
Results
Compared to usual care, a 3-month exercise programme preserved appendicular lean mass (P =
0.019) and prevented gains in whole body fat mass, trunk fat mass and percentage fat with group
differences of -1.4 kg (P = 0.001), -0.9 kg (P = 0.008) and -1.3% (P < 0.001), respectively.
Significant between-group differences were also seen favouring the exercise group for
cardiovascular fitness (peak oxygen consumption 1.1 mL/kg/min, P = 0.004), muscular strength
(4.0-25.9 kg, P <= 0.026), lower body function (-1.1 s, P < 0.001), total cholesterol: high-density
lipoprotein-cholesterol ratio (-0.52, P = 0.028), sexual function (15.2, P = 0.028), fatigue (3.1, P =
0.042), psychological distress (-2.2, P = 0.045), social functioning (3.8, P = 0.015) and mental
health (3.6-3.8, P <= 0.022). There were no significant group differences for any other outcomes.
Conclusion
Commencing a supervised exercise programme involving aerobic and resistance exercise when
initiating ADT significantly reduced treatment toxicity, while improving social functioning and
mental health. Concurrent prescription of supervised exercise when initiating ADT is therefore
advised to minimise morbidity associated with severe hypogonadism.
文献类型: Article
作者关键词: prostate cancer; androgen deprivation; exercise; resistance; aerobic
KeyWords Plus: QUALITY-OF-LIFE; CARDIORESPIRATORY FITNESS; RESISTANCE
EXERCISE;
PHYSICAL-ACTIVITY;
AEROBIC
EXERCISE;
OLDER-ADULTS;
HELP-SEEKING; MEN; SUPPRESSION; MUSCLE
地 址 : [Cormie, Prue; Galvao, Daniel A.; Spry, Nigel; Joseph, David; Taaffe, Dennis R.;
Chambers, Suzanne K.; Newton, Robert U.] Edith Cowan Univ, ECU Hlth & Wellness Inst,
Joondalup, WA 6027, Australia.
[Spry, Nigel; Chee, Raphael] Genesis Canc Care, Joondalup, Australia.
[Spry, Nigel; Joseph, David] Univ Western Australia, Sir Charles Gairdner Hosp, Dept Radiat
Oncol, Nedlands, WA 6009, Australia.
[Spry, Nigel; Joseph, David; Chee, Raphael] Univ Western Australia, Fac Med, Nedlands, WA
6009, Australia.
[Taaffe, Dennis R.] Univ Newcastle, Sch Environm & Life Sci, Ourimbah, Australia.
[Chambers, Suzanne K.] Griffith Univ, Griffith Hlth Inst, Southport, Qld 4215, Australia.
[Chambers, Suzanne K.] Canc Council Queensland, Brisbane, Qld, Australia.
[Chambers, Suzanne K.] Prostate Canc Fdn Australia, Sydney, NSW, Australia.
通讯作者地址: Cormie, P (通讯作者),Edith Cowan Univ, ECU Hlth & Wellness Inst, 270
Joondalup Dr, Joondalup, WA 6027, Australia.
电子邮件地址: [email protected]
来源出版物页码计数: 11
第 7 条，共 81 条
标题: Socio-economic factors related with the subjective well-being of the rural elderly people
living independently in China
作者: Zhou, YC (Zhou, Yicheng); Zhou, LY (Zhou, Linyi); Fu, CL (Fu, Changluan); Wang, Y
(Wang, You); Liu, QL (Liu, Qingle); Wu, HT (Wu, Hongtao); Zhang, RJ (Zhang, Rongjun);
Zheng, LF (Zheng, Linfeng)
来源出版物: INTERNATIONAL JOURNAL FOR EQUITY IN HEALTH 卷: 14 文献号: 5
DOI: 10.1186/s12939-015-0136-4 出版年: JAN 17 2015
Web of Science 核心合集中的 "被引频次": 4
被引频次合计: 4
引用的参考文献数: 46
摘要: Background: Many Chinese elderly increasingly face the serious problem of the "empty
nest" phenomenon. The elderly living independently, also called empty-nest elderly, refers to
elderly people living alone whose children left home. However few studies concerned about the
subjective well-being (SWB) of the elderly living independently.
Methods: This study employs The Memorial University of Newfoundland Scale of Happiness
(MUNSH) to explore the SWB of the elderly living independently in rural areas of Wenzhou, a
relatively developed region in China. 536 sampled are randomly selected.
Results: The results indicate that participants obtained low scores in positive affect, positive
experience, and the total SWB score, but high scores in negative affect and negative experience.
Age, low education, poor health condition and little income were found to be negatively correlated
with SWB. The SWB score of the elderly living with a spouse is higher than those who divorced
or lost their spouse and the score of women is lower than that of men. In addition, the survey
revealed that children's support has a positive influence on the SWB of the rural elderly living
independently.
Conclusions: The elderly living independently in rural Wenzhou, China have unfavorable SWB.
Poor socio-economic statuses are negative impact factors. But the children's support can help to
improve. Special attention is needed to those with lower socio-economic status and less children's
support.
文献类型: Article
作者关键词: MUNSH; SWB; The elderly living independently; Wenzhou; China
KeyWords Plus: QUALITY-OF-LIFE; MOUNTAINOUS COUNTY; OLDER-ADULTS; AREA;
CARE; SATISFACTION; LONELINESS; HAPPINESS; SAMPLE; SCALE
地址: [Zhou, Yicheng] Soochow Univ, Sch Polit & Publ Adm, Collaborat Innovat Ctr New Type
Urbanizat & Socia, Suzhou, Peoples R China.
[Zhou, Linyi] Yunnan Univ Finance & Econ, Sch Stastist & Mathemet, Kunming, Peoples R
China.
[Fu, Changluan] Zhejiang Int Studies Univ, Sch Management, Hangzhou, Zhejiang, Peoples R
China.
[Wang, You] NW Univ Xian, Sch Philosophy & Sociol, Xian 710069, Peoples R China.
[Liu, Qingle] Cent Univ Finance & Econ, Sch Govt, Beijing, Peoples R China.
[Wu, Hongtao] Soochow Univ, Affiliated Hosp 1, Suzhou, Peoples R China.
[Zhang, Rongjun] Nanjing Univ Sci & Technol, Nanjing, Jiangsu, Peoples R China.
[Zheng, Linfeng] Chinese Acad Sci, Nanjing, Jiangsu, Peoples R China.
通讯作者地址: Zhang, RJ (通讯作者),Nanjing Univ Sci & Technol, Nanjing, Jiangsu, Peoples R
China.
电子邮件地址: [email protected]; [email protected]
来源出版物页码计数: 9
第 8 条，共 81 条
标题: Screening and Treatment of Thyroid Dysfunction: An Evidence Review for the US
Preventive Services Task Force
作者: Rugge, JB (Rugge, J. Bruin); Bougatsos, C (Bougatsos, Christina); Chou, R (Chou, Roger)
来 源 出 版 物 : ANNALS OF INTERNAL MEDICINE 卷 : 162 期 : 1 页 : 35-45 DOI:
10.7326/M14-1456 出版年: JAN 6 2015
Web of Science 核心合集中的 "被引频次": 11
被引频次合计: 11
引用的参考文献数: 47
摘要: Background: In 2004, the U.S. Preventive Services Task Force found insufficient evidence
to recommend thyroid screening.
Purpose: To update the 2004 U.S. Preventive Services Task Force review on the benefits and
harms of screening and treatment of subclinical and undiagnosed overt hypothyroidism and
hyperthyroidism in adults without goiter or thyroid nodules.
Data Sources: MEDLINE and Cochrane databases through July 2014.
Study Selection: Randomized, controlled trials and observational studies of screening and
treatment.
Data Extraction: One investigator abstracted data, and a second investigator confirmed; 2
investigators independently assessed study quality.
Data Synthesis: No study directly assessed benefits and harms of screening versus no screening.
For subclinical hypothyroidism (based on thyroid-stimulating hormone levels of 4.1 to 11.0
mIU/L), 1 fair-quality cohort study found that treatment of subclinical hypothyroidism was
associated with decreased risk for coronary heart disease events versus no treatment. No study
found that treatment was associated with improved quality of life, cognitive function, blood
pressure, or body mass index versus no treatment. Effects of treatment versus no treatment showed
potential beneficial effects on lipid levels, but effects were inconsistent, not statistically significant
in most studies, and of uncertain clinical significance (difference, -0.7 to 0 mmol/L [-28 to 0
mg/dL] for total cholesterol levels and -0.6 to 0.1 mmol/L [-22 to 2 mg/dL] for low-density
lipoprotein cholesterol levels). Treatment harms were poorly studied and sparsely reported. Two
poorquality studies evaluated treatment of subclinical hyperthyroidism but examined intermediate
outcomes. No study evaluated treatment versus no treatment of screen-detected, undiagnosed
overt thyroid dysfunction.
Limitation: English-language articles only, no treatment study performed in the United States, and
small trials with short duration that used different dosage protocols.
Conclusion: More research is needed to determine the clinical benefits associated with thyroid
screening.
文献类型: Review
KeyWords
Plus:
CORONARY-HEART-DISEASE;
MILD
SUBCLINICAL
HYPOTHYROIDISM; PLACEBO-CONTROLLED TRIAL; INTIMA-MEDIA THICKNESS;
L-THYROXINE THERAPY; DOUBLE-BLIND; ENDOTHELIAL FUNCTION; SERUM
THYROTROPIN; CROSSOVER TRIAL; OLDER-ADULTS
地址: [Rugge, J. Bruin; Bougatsos, Christina; Chou, Roger] Oregon Hlth & Sci Univ, Portland,
OR 97239 USA.
通讯作者地址: Rugge, JB (通讯作者),Oregon Hlth & Sci Univ, Mail Code FM,3181 Southwest
Sam Jackson Pk Rd, Portland, OR 97239 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 11
第 9 条，共 81 条
标题: The comparison of quality of life among people with mild dementia in nursing home and
home care-a preliminary report
作者: Nikmat, AW (Nikmat, Azlina W.); Hawthorne, G (Hawthorne, Graeme); Al-Mashoor, SH
(Al-Mashoor, Syed H.)
来源出版物: DEMENTIA-INTERNATIONAL JOURNAL OF SOCIAL RESEARCH AND
PRACTICE 卷: 14 期: 1 页: 114-125 DOI: 10.1177/1471301213494509 出版年: JAN 2015
Web of Science 核心合集中的 "被引频次": 5
被引频次合计: 5
引用的参考文献数: 47
摘要: Background: Living arrangements play an important role in determining the quality of life
(QoL) of people with dementia. Although informal care (home-based) is favored, the transition to
formal (institutional) care often becomes necessary, especially in the later stages of dementia.
Nevertheless, there is currently no definitive evidence showing that informal or formal care
provides a higher QoL for those with dementia.
Objective: To compare the QoL of people with dementia in the nursing home and home care, and
identify factors that differentiate their QoL.
Design and methods: This was a cross-sectional survey. A total of 49 people with dementia >= 60
years old were recruited from government nursing homes and hospitals (home care). Consenting
participants were assessed on cognitive severity, QoL, activities of daily living (ADLs),
depression, and social isolation/ connectedness by the Short Mini Mental State Examination
(SMMSE), the WHO-8 (the EUROHIS-QOL), Short Assessment of Quality of Life (AQoL-8),
Barthel Index (BI), Cornell Scale for Depression (CSDD), and Friendship Scale (FS).
Results: There were significant differences in QoL, HRQoLs, ADLs, and social connectedness
among people with dementia in home care (n = 19) and those in nursing homes (n = 30) (p< 0.01).
No significant differences were found by socio-demographic factors, cognitive severity, or
depression between the study cohorts.
Conclusions: Older adults with dementia who were living at home experienced higher QoL,
ADLs, and social connectedness compared with those living in institutional care. Support should
be provided enabling home care and empowering caregivers to provide better care for people with
dementia.
文献类型: Article
作者关键词: dementia; home care; nursing homes; quality of life
KeyWords Plus: GERIATRIC DEPRESSION SCALE; MINI-MENTAL-STATE; COGNITIVE
IMPAIRMENT; CORNELL SCALE; OLDER-PEOPLE; INSTITUTIONALIZATION;
LONELINESS; INSTRUMENT; PREDICTORS; DISEASE
地址: [Nikmat, Azlina W.; Al-Mashoor, Syed H.] Univ Teknol MARA, Shah Alam, Malaysia.
[Hawthorne, Graeme] Univ Melbourne, Melbourne, Vic 3010, Australia.
通讯作者地址: Nikmat, AW (通讯作者),Level 1 North Royal Melbourne Hosp, Mental Hlth
Evaluat Unit, Dept Psychiat, Grattan St, Parkville, Vic 3050, Australia.
电子邮件地址: [email protected]
来源出版物页码计数: 12
第 10 条，共 81 条
标题: Impact of Exercise Type and Dose on Pain and Disability in Knee Osteoarthritis
作者: Juhl, C (Juhl, C.); Christensen, R (Christensen, R.); Roos, EM (Roos, E. M.); Zhang, W
(Zhang, W.); Lund, H (Lund, H.)
来 源 出 版 物 : ARTHRITIS & RHEUMATOLOGY 卷 : 66 期 : 3 页 : 622-636 DOI:
10.1002/art.38290 出版年: MAR 2014
Web of Science 核心合集中的 "被引频次": 43
被引频次合计: 46
引用的参考文献数: 74
摘要: Objective. To identify the optimal exercise program, characterized by type and intensity of
exercise, length of program, duration of individual supervised sessions, and number of sessions
per week, for reducing pain and patient-reported disability in knee osteoarthritis (OA).
Methods. A systematic review and meta-analysis of randomized controlled trials were performed.
Standardized mean differences (SMDs) were combined using a random-effects model. Study-level
covariates were applied in meta-regression analyses in order to reduce between-study
heterogeneity.
Results. Forty-eight trials were included. Similar effects in reducing pain were found for aerobic,
resistance, and performance exercise (SMD 0.67, 0.62, and 0.48, respectively; P = 0.733). These
single-type exercise programs were more efficacious than programs that included different
exercise types (SMD 0.61 versus 0.16; P < 0.001). The effect of aerobic exercise on pain relief
increased with an increased number of supervised sessions (slope 0.022 [95% confidence interval
0.002, 0.043]). More pain reduction occurred with quadriceps-specific exercise than with lower
limb exercise (SMD 0.85 versus 0.39; P = 0.005) and when supervised exercise was performed at
least 3 times a week (SMD 0.68 versus 0.41; P = 0.017). No impact of intensity, duration of
individual sessions, or patient characteristics was found. Similar results were found for the effect
on patient-reported disability.
Conclusion. Optimal exercise programs for knee OA should have one aim and focus on improving
aerobic capacity, quadriceps muscle strength, or lower extremity performance. For best results, the
program should be supervised and carried out 3 times a week. Such programs have a similar effect
regardless of patient characteristics, including radiographic severity and baseline pain.
文献类型: Article
KeyWords Plus: RANDOMIZED CONTROLLED-TRIAL; PATIENT REPORTED OUTCOMES;
CONTROLLED CLINICAL-TRIAL; HOME-BASED EXERCISE; QUALITY-OF-LIFE;
OLDER-ADULTS;
FUNCTIONAL
STATUS;
HIP
OSTEOARTHRITIS;
EDUCATION-PROGRAM; HIGH-INTENSITY
地址: [Juhl, C.; Christensen, R.; Roos, E. M.; Lund, H.] Univ Southern Denmark, DK-5230
Odense M, Denmark.
[Juhl, C.] Copenhagen Univ Hosp, Gentofte, Denmark.
[Christensen, R.] Copenhagen Univ Hosp, Parker Inst, Frederiksberg, Denmark.
[Zhang, W.] Univ Nottingham, Nottingham NG7 2RD, England.
通讯作者地址: Juhl, C (通讯作者),Univ Southern Denmark, Dept Sports Sci & Clin Biomech,
Res Unit Musculoskeletal Funct & Physiotherapy, Campusvej 55, DK-5230 Odense M, Denmark.
电子邮件地址: [email protected]
来源出版物页码计数: 15
第 11 条，共 81 条
标题: Well-being and Mobility: A Theoretical Framework and Literature Review Focusing on
Older People
作者: Nordbakke, S (Nordbakke, Susanne); Schwanen, T (Schwanen, Tim)
来源出版物: MOBILITIES 卷: 9 期: 1 页: 104-129 DOI: 10.1080/17450101.2013.784542 出
版年: JAN 2 2014
Web of Science 核心合集中的 "被引频次": 11
被引频次合计: 11
引用的参考文献数: 84
摘要: There is an increasing attention for how mobility is associated with well-being amongst
people in general and older adults in particular. Comparisons across research projects and articles
are, however, hampered by the different understandings and conceptualisations of well-being that
are employed. We, firstly, develop a heuristic framework for understanding the concept of
well-being, and secondly, use this to explore possible linkages between well-being and mobility
and to critically examine the various conceptualisations of well-being in research on mobility in
later life. It is argued that future work on well-being and mobility should consider both the
objective and the subjective and the hedonic and eudaimonic dimensions of well-being, and
should pay detailed attention to the multiple ways in which well-being and its linkages to mobility
are context-dependent and shaped by the particularities of time and place.
文献类型: Article
作者关键词: Well-being; Quality of life; Mobility; Motility; Ageing; Literature review
KeyWords Plus: QUALITY-OF-LIFE; INCREASED DEPRESSIVE SYMPTOMS; DRIVING
CESSATION; SUBJECTIVE INDICATORS; HAPPINESS; SCALES; ADULTS; WOMEN;
TRANSPORTATION; SATISFACTION
地址: [Nordbakke, Susanne] Univ Oslo, Inst Transport Econ, NO-0349 Oslo, Norway.
[Schwanen, Tim] Univ Oxford, Sch Geog & Environm, Oxford, England.
通讯作者地址: Nordbakke, S (通讯作者),Univ Oslo, Inst Transport Econ, Gaustadalleen 21,
NO-0349 Oslo, Norway.
电子邮件地址: [email protected]
来源出版物页码计数: 26
第 12 条，共 81 条
标题: Statins and Cognitive Function
作者: Richardson, K (Richardson, Karl); Schoen, M (Schoen, Marisa); French, B (French,
Benjamin); Umscheid, CA (Umscheid, Craig A.); Mitchell, MD (Mitchell, Matthew D.); Arnold,
SE (Arnold, Steven E.); Heidenreich, PA (Heidenreich, Paul A.); Rader, DJ (Rader, Daniel J.);
deGoma, EM (deGoma, Emil M.)
来 源 出 版 物 : ANNALS OF INTERNAL MEDICINE 卷 : 159 期 : 10 页 : 688-+ DOI:
10.7326/0003-4819-159-10-201311190-00007 出版年: NOV 19 2013
Web of Science 核心合集中的 "被引频次": 56
被引频次合计: 56
引用的参考文献数: 85
摘要: Background: Despite the U. S. Food and Drug Administration (FDA) warning regarding
cognitive impairment, the relationship between statins and cognition remains unknown.
Purpose: To examine the effect of statins on cognition.
Data Sources: PubMed, Embase, and Cochrane Library from inception through October 2012;
FDA databases from January 1986 through March 2012.
Study Selection: Randomized, controlled trials (RCTs) and cohort, case-control, and
cross-sectional studies evaluating cognition in patients receiving statins.
Data Extraction: Two reviewers extracted data, 1 reviewer assessed study risk of bias, and 1
reviewer checked all assessments.
Data Synthesis: Among statin users, low-quality evidence suggested no increased incidence of
Alzheimer disease and no difference in cognitive performance related to procedural memory,
attention, or motor speed. Moderate-quality evidence suggested no increased incidence of
dementia or mild cognitive impairment or any change in cognitive performance related to global
cognitive performance scores, executive function, declarative memory, processing speed, or
visuoperception. Examination of the FDA post-marketing surveillance databases revealed a low
reporting rate for cognitive-related adverse events with statins that was similar to the rates seen
with other commonly prescribed cardiovascular medications.
Limitations: The absence of many well-powered RCTs for most outcomes resulted in final
strengths of evidence that were low or moderate. Imprecision, inconsistency, and risk of bias also
limited the strength of findings.
Conclusion: Larger and better-designed studies are needed to draw unequivocal conclusions about
the effect of statins on cognition. Published data do not suggest an adverse effect of statins on
cognition; however, the strength of available evidence is limited, particularly with regard to
high-dose statins.
文献类型: Review
KeyWords Plus: LIPID-LOWERING AGENTS; RANDOMIZED CONTROLLED-TRIAL;
MODERATE
ALZHEIMER-DISEASE;
PLACEBO-CONTROLLED
TRIAL;
QUALITY-OF-LIFE; INCIDENT DEMENTIA; CARDIOVASCULAR HEALTH; REDUCTASE
INHIBITORS; CLINICAL-TRIALS; OLDER ADULTS
地址: Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA.
Univ Penn Hlth Syst, Philadelphia, PA USA.
Stanford Univ, Med Ctr, Stanford, CA 94305 USA.
通讯作者地址: deGoma, EM (通讯作者),Perelman Ctr Adv Med, Heart & Vasc Ctr, 3400 Civ Ctr
Blvd, Philadelphia, PA 19104 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 11
第 13 条，共 81 条
标题: Screening for Cognitive Impairment in Older Adults: A Systematic Review for the U.S.
Preventive Services Task Force
作者: Lin, JS (Lin, Jennifer S.); O'Connor, E (O'Connor, Elizabeth); Rossom, RC (Rossom,
Rebecca C.); Perdue, LA (Perdue, Leslie A.); Eckstrom, E (Eckstrom, Elizabeth)
来 源 出 版 物 : ANNALS OF INTERNAL MEDICINE 卷 : 159 期 : 9 页 : 601-612 DOI:
10.7326/0003-4819-159-9-201311050-00730 出版年: NOV 5 2013
Web of Science 核心合集中的 "被引频次": 58
被引频次合计: 64
引用的参考文献数: 315
摘 要 : Background: Earlier identification of cognitive impairment may reduce patient and
caregiver morbidity.
Purpose: To systematically review the diagnostic accuracy of brief cognitive screening instruments
and the benefits and harms of pharmacologic and nonpharmacologic interventions for early
cognitive impairment.
Data Sources: MEDLINE, PsycINFO, and the Cochrane Central Register of Controlled Trials
through December 2012; systematic reviews; clinical trial registries; and experts.
Study Selection: English-language studies of fair to good quality, primary care feasible screening
instruments, and treatments aimed at persons with mild cognitive impairment or mild to moderate
dementia.
Data Extraction: Dual quality assessment and abstraction of relevant study details.
Data Synthesis: The Mini-Mental State Examination (k = 25) is the most thoroughly studied
instrument but is not available for use without cost. Publicly available instruments with adequate
test performance to detect dementia include the Clock Drawing Test (k = 7), Mini-Cog (k = 4),
Memory Impairment Screen (k = 5), Abbreviated Mental Test (k = 4), Short Portable Mental
Status Questionnaire (k = 4), Free and Cued Selective Reminding Test (k = 2), 7-Minute Screen (k
= 2), and Informant Questionnaire on Cognitive Decline in the Elderly (k = 5). Medications
approved by the U.S. Food and Drug Administration for Alzheimer disease (k = 58) and caregiver
interventions (k = 59) show a small benefit of uncertain clinical importance for patients and their
caregivers. Small benefits are also limited by common adverse effects of acetylcholinesterase
inhibitors and limited availability of complex caregiver interventions. Although promising,
cognitive stimulation (k = 6) and exercise (k = 10) have limited evidence to support their use in
persons with mild to moderate dementia or mild cognitive impairment.
Limitation: Limited studies in persons with dementia other than Alzheimer disease and sparse
reporting of important, health outcomes.
Conclusion: Brief instruments to screen for cognitive impairment can adequately detect dementia,
but there is no empirical evidence that screening improves decision making. Whether
interventions for patients or their caregivers have a clinically significant effect in persons with
earlier detected cognitive impairment is still unclear.
文献类型: Review
KeyWords Plus: RANDOMIZED CONTROLLED-TRIAL; PLACEBO-CONTROLLED TRIAL;
MODERATE
ALZHEIMERS-DISEASE;
MENTAL-STATE-EXAMINATION;
CLOCK
DRAWING TEST; DOUBLE-BLIND TRIAL; QUALITY-OF-LIFE; MODIFIED TELEPHONE
INTERVIEW; CLINICAL-PRACTICE GUIDELINE; PROBABLE VASCULAR DEMENTIA
地址: [Lin, Jennifer S.; O'Connor, Elizabeth; Perdue, Leslie A.] Kaiser Permanente Northwest, Ctr
Hlth Res, Portland, OR 97227 USA.
[Rossom, Rebecca C.] HealthPartners Inst Educ & Res, Minneapolis, MN 55440 USA.
[Eckstrom, Elizabeth] Oregon Hlth & Sci Univ, Dept Med, Portland, OR 97239 USA.
通讯作者地址: Lin, JS (通讯作者),Kaiser Permanente Northwest, Ctr Hlth Res, Portland, OR
97227 USA.
来源出版物页码计数: 12
第 14 条，共 81 条
标题: Physical Activity and the Prevention of Depression A Systematic Review of Prospective
Studies
作者: Mammen, G (Mammen, George); Faulkner, G (Faulkner, Guy)
来源出版物 : AMERICAN JOURNAL OF PREVENTIVE MEDICINE 卷 : 45 期 : 5 页 :
649-657 DOI: 10.1016/j.amepre.2013.08.001 出版年: NOV 2013
Web of Science 核心合集中的 "被引频次": 62
被引频次合计: 63
引用的参考文献数: 55
摘要: Context: Given its high prevalence and impact on quality of life, more research is needed in
identifying factors that may prevent depression. This review examined whether physical activity
(PA) is protective against the onset of depression.
Evidence acquisition: A comprehensive search was conducted up until December 2012 in the
following databases: MEDLINE, Embase, PubMed, PsycINFO, SPORTDiscus, and Cochrane
Database of Systematic Reviews. Data were analyzed between July 2012 and February 2013.
Articles were chosen for the review if the study used a prospective-based, longitudinal design and
examined relationships between PA and depression over at least two time intervals. A formal
quality assessment for each study also was conducted independently by the two reviewers.
Evidence synthesis: The initial search yielded a total of 6363 citations. After a thorough selection
process, 30 studies were included for analyses. Among these, 25 studies demonstrated that
baseline PA was negatively associated with a risk of subsequent depression. The majority of these
studies were of high methodologic quality, providing consistent evidence that PA may prevent
future depression. There is promising evidence that any level of PA, including low levels (e.g.,
walking <150 minutes/weeks), can prevent future depression.
Conclusions: From a population health perspective, promoting PA may serve as a valuable mental
health promotion strategy in reducing the risk of developing depression. (Am J Prey Med
2013;45(5):649-657) Crown Copyright (C) 2013 Published by Elsevier Inc. on behalf of American
Journal of Preventive Medicine
文献类型: Review
KeyWords Plus: OLDER-ADULTS; SYMPTOMS;
POPULATION; OBESITY; HEALTH; COHORT; RISK
TIME;
WOMEN;
EXERCISE;
地址: [Mammen, George; Faulkner, Guy] Univ Toronto, Fac Kinesiol & Phys Educ, Toronto, ON,
Canada.
[Faulkner, Guy] Ctr Addict & Mental Hlth, Toronto, ON, Canada.
通讯作者地址: Mammen, G (通讯作者),55 Harbord St, Toronto, ON M5S 2W6, Canada.
电子邮件地址: [email protected]
来源出版物页码计数: 9
第 15 条，共 81 条
标题: Health Disparities Among Lesbian, Gay, and Bisexual Older Adults: Results From a
Population-Based Study
作者: Fredriksen-Goldsen, KI (Fredriksen-Goldsen, Karen I.); Kim, HJ (Kim, Hyun-Jun); Barkan,
SE (Barkan, Susan E.); Muraco, A (Muraco, Anna); Hoy-Ellis, CP (Hoy-Ellis, Charles P.)
来源出版物: AMERICAN JOURNAL OF PUBLIC HEALTH 卷: 103 期: 10 页: 1802-1809
DOI: 10.2105/AJPH.2012.301110 出版年: OCT 2013
Web of Science 核心合集中的 "被引频次": 47
被引频次合计: 47
引用的参考文献数: 71
摘要: Objectives. We investigated health disparities among lesbian, gay, and bisexual (LGB)
adults aged 50 years and older.
Methods. We analyzed data from the 2003-2010 Washington State Behavioral Risk Factor
Surveillance System (n = 96 992) on health outcomes, chronic conditions, access to care,
behaviors, and screening by gender and sexual orientation with adjusted logistic regressions.
Results. LGB older adults had higher risk of disability, poor mental health, smoking, and
excessive drinking than did heterosexuals. Lesbians and bisexual women had higher risk of
cardiovascular disease and obesity, and gay and bisexual men had higher risk of poor physical
health and living alone than did heterosexuals. Lesbians reported a higher rate of excessive
drinking than did bisexual women; bisexual men reported a higher rate of diabetes and a lower
rate of being tested for HIV than did gay men.
Conclusions. Tailored interventions are needed to address the health disparities and unique health
needs of LGB older adults. Research across the life course is needed to better understand health
disparities by sexual orientation and age, and to assess subgroup differences within these
communities.
文献类型: Article
KeyWords Plus: CHRONICALLY ILL MIDLIFE; SEXUAL-MINORITY WOMEN;
QUALITY-OF-LIFE;
MENTAL-HEALTH;
UNITED-STATES;
CARDIOVASCULAR-DISEASE; RISK-FACTORS; FOLLOW-UP; ORIENTATION; CANCER
地址: [Fredriksen-Goldsen, Karen I.; Kim, Hyun-Jun; Barkan, Susan E.; Hoy-Ellis, Charles P.]
Univ Washington, Sch Social Work, Seattle, WA 98195 USA.
[Muraco, Anna] Loyola Marymount Univ, Dept Sociol, Los Angeles, CA 90045 USA.
通讯作者地址: Fredriksen-Goldsen, KI (通讯作者),4101 15th Ave NE,Box 354900, Seattle, WA
98105 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 8
第 16 条，共 81 条
标题: Effects of Intensive Diet and Exercise on Knee Joint Loads, Inflammation, and Clinical
Outcomes Among Overweight and Obese Adults With Knee Osteoarthritis The IDEA Randomized
Clinical Trial
作者: Messier, SP (Messier, Stephen P.); Mihalko, SL (Mihalko, Shannon L.); Legault, C (Legault,
Claudine); Miller, GD (Miller, Gary D.); Nicklas, BJ (Nicklas, Barbara J.); DeVita, P (DeVita,
Paul); Beavers, DP (Beavers, Daniel P.); Hunter, DJ (Hunter, David J.); Lyles, MF (Lyles, Mary
F.); Eckstein, F (Eckstein, Felix); Williamson, JD (Williamson, Jeff D.); Carr, JJ (Carr, J. Jeffery);
Guermazi, A (Guermazi, Ali); Loeser, RF (Loeser, Richard F.)
来源出版物: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 卷: 310 期:
12 页: 1263-1273 DOI: 10.1001/jama.2013.277669 出版年: SEP 25 2013
Web of Science 核心合集中的 "被引频次": 82
被引频次合计: 83
引用的参考文献数: 51
摘要: IMPORTANCE Knee osteoarthritis (OA), a common cause of chronic pain and disability,
has biomechanical and inflammatory origins and is exacerbated by obesity.
OBJECTIVE To determine whether a >= 10% reduction in body weight induced by diet, with or
without exercise, would improve mechanistic and clinical outcomes more than exercise alone.
DESIGN, SETTING, AND PARTICIPANTS Single-blind, 18-month, randomized clinical trial at
Wake Forest University between July 2006 and April 2011. The diet and exercise interventions
were center-based with options for the exercise groups to transition to a home-based program.
Participants were 454 overweight and obese older community-dwelling adults (age >= 55 years
with body mass index of 27-41) with pain and radiographic knee OA.
INTERVENTIONS Intensive diet-induced weight loss plus exercise, intensive diet-induced
weight loss, or exercise.
MAIN OUTCOMES AND MEASURES Mechanistic primary outcomes: knee joint compressive
force and plasma IL-6 levels; secondary clinical outcomes: self-reported pain (range, 0-20),
function (range, 0-68), mobility, and health-related quality of life (range, 0-100).
RESULTS At 18 months, 399 participants (88%) completed the study. Compared with exercise
participants, knee compressive forces were lower in diet participants and IL-6 levels were lower in
diet and diet + exercise participants.
[GRAPHICS]
CONCLUSIONS AND RELEVANCE Among overweight and obese adults with knee OA, after
18 months, participants in the diet + exercise and diet groups had more weight loss and greater
reductions in IL-6 levels than those in the exercise group; those in the diet group had greater
reductions in knee compressive force than those in the exercise group.
文献类型: Article
KeyWords Plus: INDUCED WEIGHT-LOSS; OLDER-ADULTS; IMPORTANT DIFFERENCE;
OSTEO-ARTHRITIS; PAIN; CARTILAGE; MARKERS; MUSCLE; HIP; PROGRESSION
地址: [Messier, Stephen P.; Mihalko, Shannon L.; Miller, Gary D.; Nicklas, Barbara J.; Loeser,
Richard F.] Wake Forest Univ, Dept Hlth & Exercise Sci, Winston Salem, NC 27109 USA.
[Legault, Claudine; Beavers, Daniel P.] Wake Forest Sch Med, Div Publ Hlth Sci, Winston Salem,
NC USA.
[Messier, Stephen P.; Nicklas, Barbara J.; Lyles, Mary F.; Williamson, Jeff D.] Wake Forest Sch
Med, Sect Gerontol & Geriatr Med, Winston Salem, NC USA.
[DeVita, Paul] E Carolina Univ, Dept Kinesiol, Greenville, NC USA.
[Hunter, David J.] Univ Sydney, Dept Rheumatol, Northern Clin Sch, Sydney, NSW 2006,
Australia.
[Eckstein, Felix] Paracelsus Med Univ, Inst Anat & Musculoskeletal Res, Salzburg, Austria.
[Eckstein, Felix] Chondrometrics, Ainring, Germany.
[Carr, J. Jeffery] Wake Forest Sch Med, Dept Radiol, Winston Salem, NC USA.
[Guermazi, Ali] Boston Univ, Sch Med, Dept Radiol, Boston, MA 02118 USA.
[Loeser, Richard F.] Wake Forest Sch Med, Sect Mol Med, Winston Salem, NC USA.
通讯作者地址: Messier, SP (通讯作者),Wake Forest Univ, Dept Hlth & Exercise Sci, JB Snow
Biomech Lab, Winston Salem, NC 27109 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 11
第 17 条，共 81 条
标题: Cognitive frailty: Rational and definition from an (IANA/IAGG) International Consensus
Group
作者: Kelaiditi, E (Kelaiditi, E.); Cesari, M (Cesari, M.); Canevelli, M (Canevelli, M.); Van Kan,
GA (Van Kan, G. Abellan); Ousset, PJ (Ousset, P. -J.); Gillette-Guyonnet, S (Gillette-Guyonnet,
S.); Ritz, P (Ritz, P.); Duveau, F (Duveau, F.); Soto, ME (Soto, M. E.); Provencher, V (Provencher,
V.); Nourhashemi, F (Nourhashemi, F.); Salva, A (Salva, A.); Robert, P (Robert, P.); Andrieu, S
(Andrieu, S.); Rolland, Y (Rolland, Y.); Touchon, J (Touchon, J.); Fitten, JL (Fitten, J. L.); Vellas,
B (Vellas, B.)
来源出版物: JOURNAL OF NUTRITION HEALTH & AGING 卷: 17 期: 9 页: 726-734 DOI:
10.1007/s12603-013-0367-2 出版年: SEP 2013
Web of Science 核心合集中的 "被引频次": 48
被引频次合计: 48
引用的参考文献数: 81
摘要: The frailty syndrome has recently attracted attention of the scientific community and public
health organizations as precursor and contributor of age-related conditions (particularly disability)
in older persons. In parallel, dementia and cognitive disorders also represent major healthcare and
social priorities. Although physical frailty and cognitive impairment have shown to be related in
epidemiological studies, their pathophysiological mechanisms have been usually studied
separately. An International Consensus Group on "Cognitive Frailty" was organized by the
International Academy on Nutrition and Aging (I.A.N.A) and the International Association of
Gerontology and Geriatrics (I.A.G.G) on April 16th, 2013 in Toulouse (France). The present report
describes the results of the Consensus Group and provides the first definition of a "Cognitive
Frailty" condition in older adults. Specific aim of this approach was to facilitate the design of
future personalized preventive interventions in older persons. Finally, the Group discussed the use
of multidomain interventions focused on the physical, nutritional, cognitive and psychological
domains for improving the well-being and quality of life in the elderly. The consensus panel
proposed the identification of the so-called "cognitive frailty" as an heterogeneous clinical
manifestation characterized by the simultaneous presence of both physical frailty and cognitive
impairment. In particular, the key factors defining such a condition include: 1) presence of
physical frailty and cognitive impairment (CDR=0.5); and 2) exclusion of concurrent AD
dementia or other dementias. Under different circumstances, cognitive frailty may represent a
precursor of neurodegenerative processes. A potential for reversibility may also characterize this
entity. A psychological component of the condition is evident and concurs at increasing the
vulnerability of the individual to stressors.
文献类型: Article
作者关键词: Frailty; cognition; cognitive frailty; neurodegenerative disease; aging; elderly;
disability; clinical markers; biological markers; neuroimaging; prevention
KeyWords Plus: ALZHEIMERS ASSOCIATION WORKGROUPS; IANA TASK-FORCE;
OLDER-ADULTS;
DIAGNOSTIC
GUIDELINES;
NATIONAL
INSTITUTE;
ELDERLY-PEOPLE;
PREDICTIVE-VALIDITY;
ERMELINO
MATARAZZO;
CLINICAL-PRACTICE; PHYSICAL FRAILTY
地 址 : [Kelaiditi, E.; Cesari, M.; Canevelli, M.; Van Kan, G. Abellan; Ousset, P. -J.;
Gillette-Guyonnet, S.; Soto, M. E.; Nourhashemi, F.; Andrieu, S.; Rolland, Y.; Vellas, B.] Ctr Hosp
Univ Toulouse, Gerontopole, Toulouse, France.
[Cesari, M.; Van Kan, G. Abellan; Gillette-Guyonnet, S.; Ritz, P.; Soto, M. E.; Nourhashemi, F.;
Andrieu, S.; Rolland, Y.; Vellas, B.] Fac Med Toulouse, INSERM, UMR 1027, F-31073 Toulouse,
France.
[Cesari, M.; Andrieu, S.; Vellas, B.] Univ Toulouse III Paul Sabatier, F-31000 Toulouse, France.
[Canevelli, M.] Univ Roma La Sapienza, Dept Neurol & Psychiat, Memory Clin, Rome, Italy.
[Ritz, P.] Hop Rangueil, Pole Cardiovasc & Metab, Unite Transversale Nutr Clin, Toulouse,
France.
[Duveau, F.] Medeos Consulting, Garches, France.
[Provencher, V.] Univ Laval, Dept Readaptat, Quebec City, PQ, Canada.
[Provencher, V.] Chu Quebec, Ctr Rech, Quebec City, PQ, Canada.
[Salva, A.] Univ Autonoma Barcelona, Inst Catala Envelliment, E-08193 Barcelona, Spain.
[Robert, P.] CHU Nice, Ctr Memoire Ressources & Rech, INSERM JE Neurobiol & Psychopathol
2441, F-06202 Nice, France.
[Andrieu, S.] CHU Toulouse, Dept Publ Hlth, Toulouse, France.
[Touchon, J.] Univ Hosp Montpellier, Dept Neurol, Montpellier, France.
[Fitten, J. L.] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA.
[Fitten, J. L.] GLA VA Healthcare Syst, Los Angeles, CA USA.
通讯作者地址: Kelaiditi, E (通讯作者),Univ Toulouse III Paul Sabatier, Inst Vieillissement,
Gerontopole, 37 Allees Jules Guesde, F-31000 Toulouse, France.
电子邮件地址: [email protected]
来源出版物页码计数: 9
第 18 条，共 81 条
标题: EULAR recommendations for the non-pharmacological core management of hip and knee
osteoarthritis
作者: Fernandes, L (Fernandes, Linda); Hagen, KB (Hagen, Kare B.); Bijlsma, JWJ (Bijlsma,
Johannes W. J.); Andreassen, O (Andreassen, Oyvor); Christensen, P (Christensen, Pia);
Conaghan, PG (Conaghan, Philip G.); Doherty, M (Doherty, Michael); Geenen, R (Geenen, Rinie);
Hammond, A (Hammond, Alison); Kjeken, I (Kjeken, Ingvild); Lohmander, LS (Lohmander, L.
Stefan); Lund, H (Lund, Hans); Mallen, CD (Mallen, Christian D.); Nava, T (Nava, Tiziana);
Oliver, S (Oliver, Susan); Pavelka, K (Pavelka, Karel); Pitsillidou, I (Pitsillidou, Irene); da Silva,
JA (da Silva, Jose Antonio); de la Torre, J (de la Torre, Jenny); Zanoli, G (Zanoli, Gustavo);
Vlieland, TPMV (Vlieland, Theodora P. M. Vliet)
来源出版物: ANNALS OF THE RHEUMATIC DISEASES 卷: 72 期: 7 页: 1125-1135 DOI:
10.1136/annrheumdis-2012-202745 出版年: JUL 2013
Web of Science 核心合集中的 "被引频次": 114
被引频次合计: 120
引用的参考文献数: 142
摘要: The objective was to develop evidence -based recommendations and a research and
educational agenda for the non-pharmacological management of hip and knee osteoarthritis (OA).
The multidisciplinary task force comprised 21 experts: nurses, occupational therapists,
physiotherapists, rheumatologists, orthopaedic surgeons, general practitioner, psychologist,
dietician, clinical epidemiologist and patient representatives. After a preliminary literature review,
a first task force meeting and five Delphi rounds, provisional recommendations were formulated
in order to perform a systematic review. A literature search of Medline and eight other databases
was performed up to February 2012. Evidence was graded in categories I-IV and agreement with
the recommendations was determined through scores from 0 (total disagreement) to 10 (total
agreement). Eleven evidence-based recommendations for the non-pharmacological core
management of hip and knee OA were developed, concerning the following nine topics:
assessment, general approach, patient information and education, lifestyle changes, exercise,
weight loss, assistive technology and adaptations, footwear and work. The average level of
agreement ranged between 8.0 and 9.1. The proposed research agenda included an overall need for
more research into non-pharmacological interventions for hip OA, moderators to optimise
individualised treatment, healthy lifestyle with economic evaluation and long-term follow-up, and
the prevention and reduction of work disability. Proposed educational activities included the
required skills to teach, initiate and establish lifestyle changes. The 11 recommendations provide
guidance on the delivery of non-pharmacological interventions to people with hip or knee OA.
More research and educational activities are needed, particularly in the area of lifestyle changes.
文献类型: Review
KeyWords
Plus:
RANDOMIZED
CONTROLLED-TRIAL;
PHYSICAL-ACTIVITY
INTERVENTIONS; BEHAVIORAL GRADED ACTIVITY; LONG-TERM EFFECTIVENESS;
HOME-BASED EXERCISE; QUALITY-OF-LIFE; OLDER-ADULTS; SELF-MANAGEMENT;
CLINICAL-TRIAL; WEIGHT-LOSS
地址: [Fernandes, Linda; Hagen, Kare B.; Kjeken, Ingvild] Diakonhjemmet Hosp, Natl Resource
Ctr Rehabil Rheumatol, N-0319 Oslo, Norway.
[Bijlsma, Johannes W. J.] Univ Med Ctr Utrecht, Dept Rheumatol & Clin Immunol, Utrecht,
Netherlands.
[Andreassen, Oyvor] Diakonhjemmet Hosp, Dept Rheumatol, N-0319 Oslo, Norway.
[Christensen, Pia] Copenhagen Univ Hosp Fredriksberg, Parker Inst, Dept Rheumatol,
Copenhagen, Denmark.
[Christensen, Pia] Univ Copenhagen, Dept Nutr Exercise & Sports, Copenhagen, Denmark.
[Conaghan, Philip G.] Univ Leeds, Div Musculoskeletal Dis, Leeds, W Yorkshire, England.
[Conaghan, Philip G.] NIHR Leeds Musculoskeletal Biomed Res Unit, Leeds, W Yorkshire,
England.
[Doherty, Michael] Univ Nottingham, Nottingham NG7 2RD, England.
[Geenen, Rinie] Univ Utrecht, Dept Clin & Hlth Psychol, Utrecht, Netherlands.
[Hammond, Alison] Univ Salford, Ctr Hlth Sci Res, Salford M5 4WT, Lancs, England.
[Lohmander, L. Stefan] Lund Univ, Clin Sci Lund, Dept Orthopaed, Lund, Sweden.
[Lohmander, L. Stefan; Lund, Hans] Univ Southern Denmark, Inst Sports Sci & Clin Biomech,
Res Unit Musculoskeletal Funct & Physiotherapy, Odense, Denmark.
[Lohmander, L. Stefan] Univ Southern Denmark, Dept Orthopaed & Traumatol, Odense,
Denmark.
[Mallen, Christian D.] Keele Univ, Arthrit Res UK Primary Care Ctr, Keele ST5 5BG, Staffs,
England.
[Nava, Tiziana] Univ Studies Milan, Fac Physiotherapy, Milan, Italy.
[Oliver, Susan] Minerva Hlth Ctr, Preston, Lancs, England.
[Pavelka, Karel] Charles Univ Prague, Fac Med 1, Inst Rheumatol, Prague, Czech Republic.
[Pavelka, Karel] Charles Univ Prague, Fac Med 1, Clin Rheumatol, Prague, Czech Republic.
[da Silva, Jose Antonio] Ctr Hosp Univ Coimbra, Dept Rheumatol, Coimbra, Portugal.
[de la Torre, Jenny] Alicante Gen, Dept Rheumatol, Alicante, Spain.
[de la Torre, Jenny] Univ Hosp, Alicante, Spain.
[Zanoli, Gustavo] Univ Ferrara Casa Cura SM Maddalena, Ferrara, Italy.
[Vlieland, Theodora P. M. Vliet] Leiden Univ Med Ctr, Dept Orthopaed, Leiden, Netherlands.
通讯作者地址: Fernandes, L (通讯作者),Diakonhjemmet Hosp, Natl Resource Ctr Rehabil
Rheumatol, Postboks 23, N-0319 Oslo, Norway.
电子邮件地址: [email protected]
来源出版物页码计数: 11
第 19 条，共 81 条
标题: Physical activity in older people: a systematic review
作者: Sun, F (Sun, Fei); Norman, IJ (Norman, Ian J.); While, AE (While, Alison E.)
来源出版物: BMC PUBLIC HEALTH 卷: 13 文献号: 449 DOI: 10.1186/1471-2458-13-449 出
版年: MAY 6 2013
Web of Science 核心合集中的 "被引频次": 44
被引频次合计: 45
引用的参考文献数: 73
摘要: Background: Physical activity (PA) in older people is critically important in the prevention
of disease, maintenance of independence and improvement of quality of life. Little is known about
the physical activity of the older adults or their compliance with current physical activity
guidelines.
Methods: A systematic literature search of the published literature was conducted. Included were
published reports of original research that independently reported: the PA level of non-institutional
older adults (aged 60 years and over); and the proportion of older adults in the different samples
who met PA recommendations or guidelines. The review was restricted to studies published since
2000 to provide a current picture of older adults' PA levels.
Results: Fifty three papers were included in the review. The percentage of older adults meeting
recommended physical activity ranged from 2.4 - 83.0% across the studies. Definitions of
"recommended" physical activity in older adults varied across the studies as did approaches to
measurement which posed methodological challenges to data analysis. Older age groups were less
likely than the reference group to be regularly active, and women were less likely than men to
achieve regular physical activity, especially leisure time physical activity, when measured by both
subjective and objective criteria.
Conclusion: The review highlights the need for studies which recruit representative random
samples of community based older people and employ validated measurement methods
consistently to enable comparison of PA levels over time and between countries.
文献类型: Review
作者关键词: Physical activity; Exercise; Older people; Older adults
KeyWords Plus: FACTOR SURVEILLANCE SYSTEM; BRITISH WOMENS HEART;
UNITED-STATES; ACTIVITY GUIDELINES; BUILT ENVIRONMENT; ACTIVITY
PATTERNS; BRAZILIAN ADULTS; HEALTH BEHAVIORS; TEMPORAL TRENDS; LIFE
EXPECTANCY
地址: [Sun, Fei] Second Mil Med Univ, Sch Nursing, Shanghai 200433, Peoples R China.
[Norman, Ian J.; While, Alison E.] Kings Coll London, Florence Nightingale Sch Nursing &
Midwifery, London SE1 8WA, England.
通讯作者地址: While, AE (通讯作者),Kings Coll London, Florence Nightingale Sch Nursing &
Midwifery, 57 Waterloo Rd, London SE1 8WA, England.
电子邮件地址: [email protected]
来源出版物页码计数: 17
第 20 条，共 81 条
标题: Benefits of Physical Exercise Training on Cognition and Quality of Life in Frail Older
Adults
作者: Langlois, F (Langlois, Francis); Vu, TTM (Thien Tuong Minh Vu); Chasse, K (Chasse,
Kathleen); Dupuis, G (Dupuis, Gilles); Kergoat, MJ (Kergoat, Marie-Jeanne); Bherer, L (Bherer,
Louis)
来源出版物: JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES
AND SOCIAL SCIENCES 卷: 68 期: 3 页: 400-404 DOI: 10.1093/geronb/gbs069 出版年:
MAY 2013
Web of Science 核心合集中的 "被引频次": 35
被引频次合计: 37
引用的参考文献数: 17
摘要: Objectives. Frailty is a state of vulnerability associated with increased risks of fall,
hospitalization, cognitive deficits, and psychological distress. Studies with healthy senior suggest
that physical exercise can help improve cognition and quality of life. Whether frail older adults
can show such benefits remains to be documented.
Method. A total of 83 participants aged 61-89 years were assigned to an exercise-training group (3
times a week for 12 weeks) or a control group (waiting list). Frailty was determined by a complete
geriatric examination using specific criteria. Pre- and post-test measures assessed physical
capacity, cognitive performance, and quality of life.
Results. Compared with controls, the intervention group showed significant improvement in
physical capacity (functional capacities and physical endurance), cognitive performance
(executive functions, processing speed, and working memory), and quality of life (global quality
of life, leisure activities, physical capacity, social/family relationships, and physical health).
Benefits were overall equivalent between frail and nonfrail participants.
Discussion. Physical exercise training leads to improved cognitive functioning and psychological
well-being in frail older adults.
文献类型: Article
作者关键词: Aging; Frailty; Physical exercise; Cognitive impairment; Quality of life
KeyWords Plus: RANDOMIZED CONTROLLED-TRIAL; ELDERLY-PEOPLE; FITNESS;
VALIDATION; HEALTH
地址: [Langlois, Francis; Dupuis, Gilles; Bherer, Louis] Univ Quebec Montreal, Dept Psychol,
Montreal, PQ H3W 1W4, Canada.
[Langlois, Francis; Thien Tuong Minh Vu; Chasse, Kathleen; Kergoat, Marie-Jeanne; Bherer,
Louis] IUGM, Montreal, PQ, Canada.
[Thien Tuong Minh Vu] CHUM, Montreal, PQ, Canada.
[Dupuis, Gilles] Inst Cardiol Montreal, Montreal, PQ, Canada.
通讯作者地址: Bherer, L (通讯作者),Univ Quebec Montreal, Dept Psychol, CRIUGM, 4545
Queen Mary, Montreal, PQ H3W 1W4, Canada.
电子邮件地址: [email protected]
来源出版物页码计数: 5
第 21 条，共 81 条
标题: Frailty in elderly people
作者: Clegg, A (Clegg, Andrew); Young, J (Young, John); Iliffe, S (Iliffe, Steve); Rikkert, MO
(Rikkert, Marcel Olde); Rockwood, K (Rockwood, Kenneth)
来源出版物: LANCET 卷: 381 期: 9868 页: 752-762 DOI: 10.1016/S0140-6736(12)62167-9
出版年: MAR 2 2013
Web of Science 核心合集中的 "被引频次": 403
被引频次合计: 414
引用的参考文献数: 141
摘要: Frailty is the most problematic expression of population ageing. It is a state of vulnerability
to poor resolution of homoeostasis after a stressor event and is a consequence of cumulative
decline in many physiological systems during a lifetime. This cumulative decline depletes
homoeostatic reserves until minor stressor events trigger disproportionate changes in health status.
In landmark studies, investigators have developed valid models of frailty and these models have
allowed epidemiological investigations that show the association between frailty and adverse
health outcomes. We need to develop more efficient methods to detect frailty and measure its
severity in routine clinical practice, especially methods that are useful for primary care. Such
progress would greatly inform the appropriate selection of elderly people for invasive procedures
or drug treatments and would be the basis for a shift in the care of frail elderly people towards
more appropriate goal-directed care.
文献类型: Article
KeyWords Plus: GROWTH-FACTOR-I; COMPREHENSIVE GERIATRIC ASSESSMENT;
DWELLING OLDER-ADULTS; FUNCTIONAL ASSESSMENT QUESTIONNAIRE; MILD
COGNITIVE
IMPAIRMENT;
C-REACTIVE
PROTEIN;
QUALITY-OF-LIFE;
CARDIOVASCULAR HEALTH; DEFICIT ACCUMULATION; PHYSICAL FUNCTION
地址: [Clegg, Andrew; Young, John] Univ Leeds, Acad Unit Elderly Care & Rehabil, Bradford
BD9 6RJ, W Yorkshire, England.
[Iliffe, Steve] UCL, Dept Primary Care & Populat Hlth, London, England.
[Rikkert, Marcel Olde] Raboud Univ, Med Ctr, Nijmegen, Netherlands.
[Rockwood, Kenneth] Dalhousie Univ, Halifax, NS, Canada.
通讯作者地址: Clegg, A (通讯作者),Univ Leeds, Acad Unit Elderly Care & Rehabil, Bradford
Teaching Hosp NHS Fdn Trust, Temple Bank House,Duckworth Lane, Bradford BD9 6RJ, W
Yorkshire, England.
电子邮件地址: [email protected]
来源出版物页码计数: 11
第 22 条，共 81 条
标题: Multimorbidity in Older Adults
作者: Salive, ME (Salive, Marcel E.)
来 源 出 版 物 : EPIDEMIOLOGIC REVIEWS 卷 : 35 特 刊 : SI 页 : 75-83 DOI:
10.1093/epirev/mxs009 出版年: FEB 4 2013
Web of Science 核心合集中的 "被引频次": 51
被引频次合计: 53
引用的参考文献数: 44
摘要: Multimorbidity, the coexistence of 2 or more chronic conditions, has become prevalent
among older adults as mortality rates have declined and the population has aged. We examined
population-based administrative claims data indicating specific health service delivery to nearly
31 million Medicare fee-for-service beneficiaries for 15 prevalent chronic conditions. A total of
67% had multimorbidity, which increased with age, from 50% for persons under age 65 years to
62% for those aged 65-74 years and 81.5% for those aged >= 85 years. A systematic review
identified 16 other prevalence studies conducted in community samples that included older adults,
with median prevalence of 63% and a mode of 67%. Prevalence differences between studies are
probably due to methodological biases; no studies were comparable. Key methodological issues
arise from elements of the case definition, including type and number of chronic conditions
included, ascertainment methods, and source population. Standardized methods for measuring
multimorbidity are needed to enable public health surveillance and prevention. Multimorbidity is
associated with elevated risk of death, disability, poor functional status, poor quality of life, and
adverse drug events. Additional research is needed to develop an understanding of causal
pathways and to further develop and test potential clinical and population interventions targeting
multimorbidity.
文献类型: Article
作者关键词: aged; chronic disease; comorbidity; prevalence
KeyWords Plus: MULTIPLE CHRONIC CONDITIONS; CHRONIC DISEASE;
UNITED-STATES;
RISK-FACTORS;
PREVALENCE;
HEALTH;
COMORBIDITY;
POPULATION; DISABILITY; MORBIDITY
地址: [Salive, Marcel E.] NIA, Bethesda, MD 20892 USA.
通讯作者地址: Salive, ME (通讯作者),NIA, Geriatr Branch, Div Geriatr & Clin Gerontol, 7201
Wisconsin Ave,Suite 3C307, Bethesda, MD 20892 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 9
第 23 条，共 81 条
标题: Fear of recurrence and disease progression in long-term (>= 5 years) cancer survivors-a
systematic review of quantitative studies
作者: Koch, L (Koch, L.); Jansen, L (Jansen, L.); Brenner, H (Brenner, H.); Arndt, V (Arndt, V.)
来源出版物: PSYCHO-ONCOLOGY 卷: 22 期: 1 页: 1-11 DOI: 10.1002/pon.3022 出版年:
JAN 2013
Web of Science 核心合集中的 "被引频次": 42
被引频次合计: 43
引用的参考文献数: 67
摘 要 : Background Increasing proportions of patients diagnosed with cancer will become
long-term survivors (=5?years post-diagnosis). However, survivors may continue to experience
negative effects of cancer and/or treatment, including fear of recurrence (FoR). This review aims
to provide an overview of current knowledge on FoR, including determinants and consequences in
long-term cancer survivors, and to outline methodological and conceptual challenges that should
be addressed in future research. Methods Multiple databases including PUBMED, EMBASE, and
PsycINFO were searched to identify relevant articles. Seventeen articles were included. Data were
extracted by two reviewers and summarized following a systematic scheme. Results Even years
after initial diagnosis, cancer survivors suffer from FoR. Most studies report low or moderate
mean FoR scores, suggesting that FoR is experienced in modest intensity by most survivors.
Studies including long-term and short-term survivors indicate no significant change of FoR over
time. Lower level of education, lower level of optimism, and being Hispanic or White/Caucasian
were found to be associated with higher levels of FoR. Significant negative associations were
reported between FoR and quality of life as well as psychosocial well-being. All but three studies
were conducted in the USA. General cut-offs for severity/clinical significance have not been
defined yet. Conclusions FoR at modest intensity is experienced by most long-term cancer
survivors. Future studies should address determinants and consequences of FoR in more detail.
Validated instruments providing cut-offs for severity/clinical significance of FoR should be
developed and utilized. Efficient interventions should be implemented to reduce detrimental
effects of FoR. Copyright (c) 2012 John Wiley & Sons, Ltd.
文献类型: Review
作者关键词: cancer; oncology; long-term; fear of recurrence; survivors; systematic review
KeyWords Plus: QUALITY-OF-LIFE; SUPPORTIVE CARE NEEDS; BREAST-CANCER;
AFRICAN-AMERICAN; OLDER-ADULT; HEALTH; QUESTIONNAIRE; UNCERTAINTY;
SCALE; COMMUNICATION
地址: [Koch, L.; Jansen, L.; Brenner, H.; Arndt, V.] German Canc Res Ctr, Div Clin Epidemiol &
Aging Res, Heidelberg, Germany.
通讯作者地址: Arndt, V (通讯作者),German Canc Res Ctr, Div Clin Epidemiol & Aging Res,
POB 10 19 49, D-69009 Heidelberg, Germany.
电子邮件地址: [email protected]
来源出版物页码计数: 11
第 24 条，共 81 条
标题: Diabetes in Older Adults: A Consensus Report
作者: Kirkman, MS (Kirkman, M. Sue); Briscoe, VJ (Briscoe, Vanessa Jones); Clark, N (Clark,
Nathaniel); Florez, H (Florez, Hermes); Haas, LB (Haas, Linda B.); Halter, JB (Halter, Jeffrey B.);
Huang, ES (Huang, Elbert S.); Korytkowski, MT (Korytkowski, Mary T.); Munshi, MN (Munshi,
Medha N.); Odegard, PS (Odegard, Peggy Soule); Pratley, RE (Pratley, Richard E.); Swift, CS
(Swift, Carrie S.)
来源出版物: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 卷: 60 期: 12 页:
2342-2356 DOI: 10.1111/jgs.12035 出版年: DEC 2012
Web of Science 核心合集中的 "被引频次": 55
被引频次合计: 57
引用的参考文献数: 131
文献类型: Review
KeyWords Plus: RANDOMIZED CONTROLLED-TRIAL; NUTRITION EXAMINATION
SURVEY; INTENSIVE GLUCOSE CONTROL; LIFE-STYLE
INTERVENTION;
QUALITY-OF-LIFE; HOC EPIDEMIOLOGIC ANALYSIS; BASE-LINE CHARACTERISTICS;
NURSING-HOME RESIDENTS; BLOOD-PRESSURE CONTROL; 10-YEAR FOLLOW-UP
地址: [Halter, Jeffrey B.] Univ Michigan, Div Geriatr Med, Ann Arbor, MI 48109 USA.
[Kirkman, M. Sue] Amer Diabet Assoc, Alexandria, VA USA.
[Briscoe, Vanessa Jones] Vanderbilt Univ, Dept Med, Nashville, TN USA.
[Clark, Nathaniel] Diabet Ctr Cape Cod, Hyannis, MA USA.
[Florez, Hermes] Univ Miami, Ctr Geriatr Res Educ & Clin, Miami Vet Affairs Healthcare Syst,
Miami, FL USA.
[Haas, Linda B.] Vet Affairs Puget Sound Hlth Care Syst, Seattle, WA USA.
[Huang, Elbert S.] Univ Chicago, Gen Internal Med Sect, Chicago, IL 60637 USA.
[Korytkowski, Mary T.] Univ Pittsburgh, Div Endocrinol, Pittsburgh, PA USA.
[Munshi, Medha N.] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Boston, MA 02215
USA.
[Munshi, Medha N.] Harvard Univ, Sch Med, Joslin Diabet Ctr, Boston, MA 02115 USA.
[Odegard, Peggy Soule] Univ Washington, Dept Pharm, Seattle, WA 98195 USA.
[Pratley, Richard E.] Florida Hosp Diabet Inst, Orlando, FL USA.
[Swift, Carrie S.] Kadlec Med Ctr, Richland, WA USA.
通讯作者地址: Halter, JB (通讯作者),Univ Michigan, Div Geriatr Med, Ann Arbor, MI 48109
USA.
电子邮件地址: [email protected]
来源出版物页码计数: 15
第 25 条，共 81 条
标题: Managing patients with multimorbidity: systematic review of interventions in primary care
and community settings
作者: Smith, SM (Smith, Susan M.); Soubhi, H (Soubhi, Hassan); Fortin, M (Fortin, Martin);
Hudon, C (Hudon, Catherine); O'Dowd, T (O'Dowd, Tom)
来源出版物: BRITISH MEDICAL JOURNAL 卷: 345 文献号: e5205 DOI: 10.1136/bmj.e5205
出版年: SEP 3 2012
Web of Science 核心合集中的 "被引频次": 106
被引频次合计: 108
引用的参考文献数: 36
摘要: Objective To determine the effectiveness of interventions designed to improve outcomes in
patients with multimorbidity in primary care and community settings.
Design Systematic review.
Data sources Medline, Embase, CINAHL, CAB Health, Cochrane central register of controlled
trials, the database of abstracts of reviews of effectiveness, and the Cochrane EPOC (effective
practice and organisation of care) register (searches updated in April 2011).
Eligibility criteria Randomised controlled trials, controlled clinical trials, controlled before and
after studies, and interrupted time series analyses reporting on interventions to improve outcomes
for people with multimorbidity in primary care and community settings. Multimorbidity was
defined as two or more chronic conditions in the same individual. Outcomes included any
validated measure of physical or mental health and psychosocial status, including quality of life
outcomes, wellbeing, and measures of disability or functional status. Also included were measures
of patient and provider behaviour, including drug adherence, utilisation of health services,
acceptability of services, and costs.
Data selection Two reviewers independently assessed studies for eligibility, extracted data, and
assessed study quality. As meta-analysis of
results was not possible owing to heterogeneity in participants and interventions, a narrative
synthesis of the results from the included studies was carried out. Results 10 studies examining a
range of complex interventions totalling 3407 patients with multimorbidity were identified. All
were randomised controlled trials with a low risk of bias. Two studies described interventions for
patients with specific comorbidities. The remaining eight studies focused on multimorbidity,
generally in older patients. Consideration of the impact of socioeconomic deprivation was
minimal. All studies involved complex interventions with multiple components. In six of the 10
studies the predominant component was a change to the organisation of care delivery, usually
through case management or enhanced multidisciplinary team work. In the remaining four studies,
intervention components were predominantly patient oriented. Overall the results were mixed,
with a trend towards improved prescribing and drug adherence. The results indicated that it is
difficult to improve outcomes in this population but that interventions focusing on particular risk
factors in comorbid conditions or functional difficulties in multimorbidity may be more effective.
No economic analyses were included, although the improvements in prescribing and risk factor
management in some studies could provide potentially important cost savings.
Conclusions Evidence on the care of patients with multimorbidity is limited, despite the
prevalence of multimorbidity and its impact on patients and healthcare systems. Interventions to
date have had mixed effects, although are likely to be more effective if targeted at risk factors or
specific functional difficulties. A need exists to clearly identify patients with multimorbidity and to
develop cost effective and specifically targeted interventions that can improve health outcomes.
文献类型: Article
KeyWords
Plus:
MULTIPLE
CHRONIC
CONDITIONS;
RANDOMIZED-CONTROLLED-TRIAL;
FUNCTIONAL
DIFFICULTIES;
HOME
INTERVENTION;
OLDER-ADULTS;
PREVALENCE;
HEALTH;
CHALLENGES;
DEPRESSION; MANAGEMENT
地址: [Smith, Susan M.] Royal Coll Surgeons Ireland, Dept Gen Practice, Dublin 2, Ireland.
[Soubhi, Hassan; Fortin, Martin; Hudon, Catherine] Univ Sherbrooke, Dept Family Med,
Chicoutimi, PQ, Canada.
[O'Dowd, Tom] Trinity Coll Dublin, Ctr Hlth Sci, Dept Publ Hlth & Primary Care, Dublin 24,
Ireland.
通讯作者地址: Smith, SM (通讯作者),Royal Coll Surgeons Ireland, Dept Gen Practice, Dublin 2,
Ireland.
电子邮件地址: [email protected]
来源出版物页码计数: 10
第 26 条，共 81 条
标题: Mobility and Aging: New Directions for Public Health Action
作者: Satariano, WA (Satariano, William A.); Guralnik, JM (Guralnik, Jack M.); Jackson, RJ
(Jackson, Richard J.); Marottoli, RA (Marottoli, Richard A.); Phelan, EA (Phelan, Elizabeth A.);
Prohaska, TR (Prohaska, Thomas R.)
来源出版物: AMERICAN JOURNAL OF PUBLIC HEALTH 卷: 102 期: 8 页: 1508-1515
DOI: 10.2105/AJPH.2011.300631 出版年: AUG 2012
Web of Science 核心合集中的 "被引频次": 37
被引频次合计: 39
引用的参考文献数: 129
摘要: Optimal mobility, defined as relative ease and freedom of movement in all of its forms, is
central to healthy aging. Mobility is a significant consideration for research, practice, and policy in
aging and public health. We examined the public health burdens of mobility disability, with a
particular focus on leading public health interventions to enhance walking and driving, and the
challenges and opportunities for public health action. We propose an integrated mobility agenda,
which draws on the lived experience of older adults. New strategies for research, practice, and
policy are needed to move beyond categorical promotion programs in walking and driving to
establish a comprehensive program to enhance safe mobility in all its forms. (Am J Public Health.
2012; 102:1508-1515. doi:10.2105/AJPH.2011.300631)
文献类型: Article
KeyWords Plus: INCREASED DEPRESSIVE SYMPTOMS; NEIGHBORHOOD WALKING
ACTIVITY;
PHYSICAL-ACTIVITY
PROGRAMS;
US
ELDERLY
PERSONS;
QUALITY-OF-LIFE; OLDER-ADULTS; DRIVING CESSATION; BUILT ENVIRONMENT;
MOTOR-VEHICLE; ECOLOGICAL PERSPECTIVE
地址: [Satariano, William A.] Univ Calif Berkeley, Sch Publ Hlth, Berkeley, CA 94720 USA.
[Guralnik, Jack M.] Univ Maryland, Sch Med, Baltimore, MD 21201 USA.
[Jackson, Richard J.] Univ Calif Los Angeles, Sch Publ Hlth, Los Angeles, CA 90024 USA.
[Marottoli, Richard A.] Yale Univ, Sch Med, New Haven, CT USA.
[Phelan, Elizabeth A.] Univ Washington, Sch Med, Seattle, WA USA.
[Prohaska, Thomas R.] Univ Illinois, Sch Publ Hlth, Chicago, IL USA.
通讯作者地址: Satariano, WA (通讯作者),Univ Calif Berkeley, Sch Publ Hlth, Berkeley, CA
94720 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 8
第 27 条，共 81 条
标 题 : A simple frailty questionnaire (FRAIL) predicts outcomes in middle aged African
Americans
作者: Morley, JE (Morley, J. E.); Malmstrom, TK (Malmstrom, T. K.); Miller, DK (Miller, D. K.)
来源出版物: JOURNAL OF NUTRITION HEALTH & AGING 卷: 16 期: 7 页: 601-608 DOI:
10.1007/s12603-012-0084-2 出版年: JUL 2012
Web of Science 核心合集中的 "被引频次": 88
被引频次合计: 90
引用的参考文献数: 36
摘要: To validate the FRAIL scale.
Longitudinal study.
Community.
Representative sample of African Americans age 49 to 65 years at onset of study.
The 5-item FRAIL scale (Fatigue, Resistance, Ambulation, Illnesses, & Loss of Weight), at
baseline and activities of daily living (ADLs), instrumental activities of daily living (IADLs),
mortality, short physical performance battery (SPPB), gait speed, one-leg stand, grip strength and
injurious falls at baseline and 9 years. Blood tests for CRP, SIL6R, STNFR1, STNFR2 and 25
(OH) vitamin D at baseline.
Cross-sectionally the FRAIL scale correlated significantly with IADL difficulties, SPPB, grip
strength and one-leg stand among participants with no baseline ADL difficulties (N=703) and
those outcomes plus gait speed in those with no baseline ADL dependencies (N=883). TNFR1 was
increased in pre-frail and frail subjects and CRP in some subgroups. Longitudinally (N=423 with
no baseline ADL difficulties or N=528 with no baseline ADL dependencies), and adjusted for the
baseline value for each outcome, being pre-frail at baseline significantly predicted future ADL
difficulties, worse one-leg stand scores, and mortality in both groups, plus IADL difficulties in the
dependence-excluded group. Being frail at baseline significantly predicted future ADL difficulties,
IADL difficulties, and mortality in both groups, plus worse SPPB in the dependence-excluded
group.
This study has validated the FRAIL scale in a late middle-aged African American population. This
simple 5-question scale is an excellent screening test for clinicians to identify frail persons at risk
of developing disability as well as decline in health functioning and mortality.
文献类型: Article
作者关键词: Frailty; African Americans; disability; physical performance; mortality
KeyWords Plus: PHYSICAL PERFORMANCE BATTERY; QUALITY-OF-LIFE; HEALTH
PROJECT; ELDERLY-PEOPLE; OLDER-ADULTS; DISABILITY; MEN; TESTOSTERONE;
ASSOCIATION; WOMEN
地址: [Morley, J. E.; Malmstrom, T. K.; Miller, D. K.] St Louis Univ, Sch Med, Dept Internal
Med, Div Geriatr, St Louis, MO 63104 USA.
通讯作者地址: Morley, JE (通讯作者),St Louis Univ, Sch Med, Dept Internal Med, Div Geriatr,
1402 S Grand Blvd, St Louis, MO 63104 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 8
第 28 条，共 81 条
标题: Effects of n-3 fatty acids, EPA v. DHA, on depressive symptoms, quality of life, memory
and executive function in older adults with mild cognitive impairment: a 6-month randomised
controlled trial
作者: Sinn, N (Sinn, Natalie); Milte, CM (Milte, Catherine M.); Street, SJ (Street, Steven J.);
Buckley, JD (Buckley, Jonathan D.); Coates, AM (Coates, Alison M.); Petkov, J (Petkov, John);
Howe, PRC (Howe, Peter R. C.)
来源出版物: BRITISH JOURNAL OF NUTRITION 卷: 107 期: 11 页: 1682-1693 DOI:
10.1017/S0007114511004788 出版年: JUN 2012
Web of Science 核心合集中的 "被引频次": 75
被引频次合计: 76
引用的参考文献数: 53
摘要: Depressive symptoms may increase the risk of progressing from mild cognitive impairment
(MCI) to dementia. Consumption of n-3 PUFA may alleviate both cognitive decline and
depression. The aim of the present study was to investigate the benefits of supplementing a diet
with n-3 PUFA, DHA and EPA, for depressive symptoms, quality of life (QOL) and cognition in
elderly people with MCI. We conducted a 6-month double-blind, randomised controlled trial. A
total of fifty people aged >65 years with MCI were allocated to receive a supplement rich in EPA
(1.67 g EPA + 0.16 g DHA/d; n 17), DHA (1.55 g DHA + 0.40 g EPA/d; n 18) or the n-6 PUFA
linoleic acid (LA; 2.2 g/d; n 15). Treatment allocation was by minimisation based on age, sex and
depressive symptoms (Geriatric Depression Scale, GDS). Physiological and cognitive
assessments, questionnaires and fatty acid composition of erythrocytes were obtained at baseline
and 6 months (completers: n 40; EPA n 13, DHA n 16, LA n 11). Compared with the LA group,
GDS scores improved in the EPA (P=0.04) and DHA (P=0.01) groups and verbal fluency (Initial
Letter Fluency) in the DHA group (P=0.04). Improved GDS scores were correlated with increased
DHA plus EPA (r 0.39, P=0.02). Improved self-reported physical health was associated with
increased DHA. There were no treatment effects on other cognitive or QOL parameters. Increased
intakes of DHA and EPA benefited mental health in older people with MCI. Increasing n-3 PUFA
intakes may reduce depressive samples with MCI.
文献类型: Article
作者关键词: Mild cognitive impairment; Dementia; Depression; n-3 Fatty acids; EPA; DHA
KeyWords
Plus:
PLACEBO-CONTROLLED
TRIAL;
ALZHEIMERS-DISEASE;
DOUBLE-BLIND; DOCOSAHEXAENOIC ACID; FISH-OIL; MAJOR DEPRESSION;
OMEGA-3-FATTY-ACIDS; SUPPLEMENTATION; DEMENTIA; HEALTH
地址: [Sinn, Natalie; Milte, Catherine M.; Buckley, Jonathan D.; Coates, Alison M.; Howe, Peter
R. C.] Univ S Australia, Sch Hlth Sci, Sansom Inst Hlth Res, Nutr Physiol Res Ctr, Adelaide, SA
5001, Australia.
[Street, Steven J.] Queensland Univ Technol, Inst Hlth & Biomed Innovat, Brisbane, Qld 4001,
Australia.
[Petkov, John] Univ S Australia, Ctr Reg Engagement, Adelaide, SA 5001, Australia.
通讯作者地址: Sinn, N (通讯作者),Univ S Australia, Sch Hlth Sci, Sansom Inst Hlth Res, Nutr
Physiol Res Ctr, GPO Box 2471, Adelaide, SA 5001, Australia.
电子邮件地址: [email protected]
来源出版物页码计数: 12
第 29 条，共 81 条
标题: Cost-effectiveness of a Multicondition Collaborative Care Intervention A Randomized
Controlled Trial
作者: Katon, W (Katon, Wayne); Russo, J (Russo, Joan); Lin, EHB (Lin, Elizabeth H. B.);
Schmittdiel, J (Schmittdiel, Julie); Ciechanowski, P (Ciechanowski, Paul); Ludman, E (Ludman,
Evette); Peterson, D (Peterson, Do); Young, B (Young, Bessie); Von Korff, M (Von Korff,
Michael)
来源出版物: ARCHIVES OF GENERAL PSYCHIATRY 卷: 69 期: 5 页: 506-514 出版年:
MAY 2012
Web of Science 核心合集中的 "被引频次": 82
被引频次合计: 83
引用的参考文献数: 42
摘要: Context: Patients with depression and poorly controlled diabetes mellitus, coronary heart
disease (CHD), or both have higher medical complication rates and higher health care costs,
suggesting that more effective care management of psychiatric and medical disease control might
also reduce medical service use and enhance quality of life.
Objective: To evaluate the cost-effectiveness of a multicondition collaborative treatment program
(TEAM-care) compared with usual primary care (UC) in outpatients with depression and poorly
controlled diabetes or CHD.
Design: Randomized controlled trial of a systematic care management program aimed at
improving depression scores and hemoglobin A(1c) (HbA(1c)), systolic blood pressure (SBP), and
low-density lipoprotein cholesterol (LDL-C) levels.
Setting: Fourteen primary care clinics of an integrated health care system.
Patients: Population-based screening identified 214 adults with depressive disorder and poorly
controlled diabetes or CHD.
Intervention: Physician-supervised nurses collaborated with primary care physicians to provide
treatment of multiple disease risk factors.
Main Outcome Measures: Blinded assessments evaluated depressive symptoms, SBP, and
HbA(1c) at baseline and at 6, 12, 18, and 24 months. Fasting LDL-C concentration was assessed
at baseline and at 12 and 24 months. Health plan accounting records were used to assess medical
service costs. Quality-adjusted life-years (QALYs) were assessed using a previously developed
regression model based on intervention vs UC differences in HbA(1c), LDL-C, and SBP levels
over 24 months.
Results: Over 24 months, compared with UC controls, intervention patients had a mean of 114
(95% CI, 79 to 149) additional depression-free days and an estimated 0.335 (95% CI, -0.18 to
0.85) additional QALYs. Intervention patients also had lower mean outpatient health costs of $594
per patient (95% CI, -$3241 to $2053) relative to UC patients.
Conclusions: For adults with depression and poorly controlled diabetes, CHD, or both, a
systematic intervention program aimed at improving depression scores and HbA(1c), SBP, and
LDL-C levels seemed to be a high-value program that for no or modest additional cost markedly
improved QALYs.
文献类型: Article
KeyWords Plus: MULTIPLE CHRONIC CONDITIONS; LATE-LIFE DEPRESSION;
PROPENSITY SCORE; CHRONIC ILLNESS; OLDER-ADULTS; HEALTH; OUTCOMES;
PREVALENCE; QUALITY; RISK
地址: [Katon, Wayne; Russo, Joan; Ciechanowski, Paul] Univ Washington, Sch Med, Dept
Psychiat & Behav Sci, Seattle, WA 98195 USA.
[Young, Bessie] Univ Washington, Sch Med, Div Nephrol, Seattle, WA 98195 USA.
[Young, Bessie] Univ Washington, Sch Med, Kidney Res Inst, Dept Med, Seattle, WA 98195
USA.
[Lin, Elizabeth H. B.; Ludman, Evette; Peterson, Do; Von Korff, Michael] Grp Hlth Cooperat
Puget Sound, Grp Hlth Res Inst, Seattle, WA 98121 USA.
[Schmittdiel, Julie] Kaiser Permanente No Calif, Div Res, Oakland, CA USA.
[Young, Bessie] Puget Sound Hlth Care Syst, Vet Adm, Primary & Specialty Care, Seattle, WA
USA.
通讯作者地址: Katon, W (通讯作者),Univ Washington, Sch Med, Dept Psychiat & Behav Sci,
Box 356560, Seattle, WA 98195 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 9
第 30 条，共 81 条
标题: Lifestyle Change and Mobility in Obese Adults with Type 2 Diabetes
作者: Rejeski, WJ (Rejeski, W. Jack); Ip, EH (Ip, Edward H.); Bertoni, AG (Bertoni, Alain G.);
Bray, GA (Bray, George A.); Evans, G (Evans, Gina); Gregg, EW (Gregg, Edward W.); Zhang, Q
(Zhang, Qiang)
团体作者: Look AHEAD Res Grp
来源出版物: NEW ENGLAND JOURNAL OF MEDICINE 卷: 366 期: 13 页: 1209-1217 出
版年: MAR 29 2012
Web of Science 核心合集中的 "被引频次": 72
被引频次合计: 75
引用的参考文献数: 42
摘要: BACKGROUND
Adults with type 2 diabetes mellitus often have limitations in mobility that increase with age. An
intensive lifestyle intervention that produces weight loss and improves fitness could slow the loss
of mobility in such patients.
METHODS
We randomly assigned 5145 overweight or obese adults between the ages of 45 and 74 years with
type 2 diabetes to either an intensive lifestyle intervention or a diabetes support-and-education
program; 5016 participants contributed data. We used hidden Markov models to characterize
disability states and mixed-effects ordinal logistic regression to estimate the probability of
functional decline. The primary outcome was self-reported limitation in mobility, with annual
assessments for 4 years.
RESULTS
At year 4, among 2514 adults in the lifestyle-intervention group, 517 (20.6%) had severe disability
and 969 (38.5%) had good mobility; the numbers among 2502 participants in the support group
were 656 (26.2%) and 798 (31.9%), respectively. The lifestyle-intervention group had a relative
reduction of 48% in the risk of loss of mobility, as compared with the support group (odds ratio,
0.52; 95% confidence interval, 0.44 to 0.63; P<0.001). Both weight loss and improved fitness (as
assessed on treadmill testing) were significant mediators of this effect (P<0.001 for both
variables). Adverse events that were related to the lifestyle intervention included a slightly higher
frequency of musculoskeletal symptoms at year 1.
CONCLUSIONS
Weight loss and improved fitness slowed the decline in mobility in overweight adults with type 2
diabetes. (Funded by the Department of Health and Human Services and others; ClinicalTrials.gov
number, NCT00017953.)
文献类型: Article
KeyWords
Plus:
QUALITY-OF-LIFE;
OLDER-ADULTS;
WEIGHT-LOSS;
PHYSICAL-ACTIVITY;
US
ADULTS;
CARDIOVASCULAR-DISEASE;
KNEE
OSTEOARTHRITIS; CLINICAL-TRIAL; UNITED-STATES; RISK-FACTORS
地址: [Rejeski, W. Jack] Wake Forest Univ, Dept Hlth & Exercise Sci, Winston Salem, NC 27109
USA.
[Ip, Edward H.; Bertoni, Alain G.; Zhang, Qiang] Wake Forest Univ, Sch Med, Winston Salem,
NC 27109 USA.
[Bray, George A.] Louisiana State Univ, Pennington Biomed Res Ctr, Baton Rouge, LA 70803
USA.
[Evans, Gina] Baylor Coll Med, Houston, TX 77030 USA.
[Gregg, Edward W.] Ctr Dis Control & Prevent, Div Diabet Translat, Atlanta, GA USA.
通讯作者地址: Rejeski, WJ (通讯作者),Wake Forest Univ, Dept Hlth & Exercise Sci, Box 7868,
Winston Salem, NC 27109 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 9
第 31 条，共 81 条
标题: The prevalence of frailty syndrome in an older population from Spain. The Toledo study for
healthy aging
作者: Garcia-Garcia, FJ (Garcia-Garcia, F. J.); Avila, GG (Gutierrez Avila, G.); Alfaro-Acha, A
(Alfaro-Acha, A.); Andres, MSA (Amor Andres, M. S.); Lanza, MDD (de la Torre Lanza, M. De
Los Angeles); Aparicio, MVE (Escribano Aparicio, M. V.); Aparicio, SH (Humanes Aparicio, S.);
Zugasti, JLL (Larrion Zugasti, J. L.); Reus, MGS (Gomez-Serranillo Reus, M.);
Rodriguez-Artalejo, F (Rodriguez-Artalejo, F.); Rodriguez-Manas, L (Rodriguez-Manas, L.)
团体作者: Toledo Study Grp
来源出版物: JOURNAL OF NUTRITION HEALTH & AGING 卷: 15 期: 10 页: 852-856
DOI: 10.1007/s12603-011-0075-8 出版年: DEC 2011
Web of Science 核心合集中的 "被引频次": 58
被引频次合计: 60
引用的参考文献数: 32
摘要: To assess the prevalence of the frailty syndrome and its associated variables among the
older adult population in the province of Toledo (Spain).
Data were taken from the Toledo Study for Healthy Aging, a population-based study conducted on
2,488 individuals aged 65 years and older. Study participants were selected by a two-stage random
sampling from the municipal census of Toledo, covering both institutionalized and community
dwelling persons from rural and urban settings. Data were collected from 2006 to 2009, and
included information on social support, activities of daily living, comorbidity, physical activity,
quality of life, depressive symptoms, and cognitive function. In addition, a nurse collected
anthropometric data, conducted tests of physical performance (walk speed, upper and lower
extremities strength, and the stand-and-sit from a chair test) and obtained a blood sample. The
diagnosis of the frailty syndrome was based on the Fried criteria (weakness, low speed, low
physical activity, exhaustion, and weight loss).
In total, 41.8% (95% confidence interval [CI] 39.4-44.2%) of the study participants were prefrail,
and 8.4% (95% CI 7.1-9.8%) were frail. There were no differences in the prevalence of frailty by
sex, level of education, occupation, marital status, or place of residence. The frequency of the
frailty syndrome increased with age, and was higher in those with disability, depression, hip
fracture and other comorbidity, such as cardiovascular disease and disorders of the central nervous
system.
The prevalence of the frailty syndrome in older Spanish adults is high and similar to that reported
in other populations in the Mediterranean basin.
文献类型: Article
作者关键词: Frailty; prevalence; elderly; cross-sectional study
KeyWords Plus: MEXICAN-AMERICANS; COGNITIVE DECLINE; WOMENS HEALTH;
MORTALITY; VALIDITY; DISEASE; MEN; ASSOCIATION; DISABILITY; PREDICTION
地址: [Garcia-Garcia, F. J.; Alfaro-Acha, A.; Amor Andres, M. S.; de la Torre Lanza, M. De Los
Angeles; Escribano Aparicio, M. V.] Complejo Hosp Toledo, Hosp Virgen Valle, Div Geriatr Med,
Toledo 45071, Spain.
[Gutierrez Avila, G.; Humanes Aparicio, S.] Consejeria Sanidad Castilla Mancha, Dept Epidemiol
& Community Hlth, Toledo, Spain.
[Larrion Zugasti, J. L.] Hosp Navarra, Div Geriatr Med, Pamplona, Spain.
[Gomez-Serranillo Reus, M.] Complejo Hosp Toledo, Hosp Virgen Valle, Dept Clin Anal, Toledo
45071, Spain.
[Rodriguez-Artalejo, F.] Univ Autonoma Madrid, CIBER Epidemiol & Publ Hlth CIBERESP, Sch
Med, Dept Prevent Med & Publ Hlth,IdiPAZ, Madrid, Spain.
[Rodriguez-Manas, L.] Hosp Univ Getafe, Div Geriatr Med, Madrid, Spain.
通讯作者地址: Garcia-Garcia, FJ (通讯作者),Complejo Hosp Toledo, Hosp Virgen Valle, Div
Geriatr Med, Toledo 45071, Spain.
电子邮件地址: [email protected]; [email protected]
来源出版物页码计数: 5
第 32 条，共 81 条
标题: Hospitalization-Associated Disability "She Was Probably Able to Ambulate, but I'm Not
Sure"
作者: Covinsky, KE (Covinsky, Kenneth E.); Pierluissi, E (Pierluissi, Edgar); Johnston, CB
(Johnston, C. Bree)
来源出版物: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 卷: 306 期:
16 页: 1782-1793 DOI: 10.1001/jama.2011.1556 出版年: OCT 26 2011
Web of Science 核心合集中的 "被引频次": 109
被引频次合计: 109
引用的参考文献数: 72
摘要: In older patients, acute medical illness that requires hospitalization is a sentinel event that
often precipitates disability. This results in the subsequent inability to live independently and
complete basic activities of daily living (ADLs). This hospitalization-associated disability occurs
in approximately one-third of patients older than 70 years of age and may be triggered even when
the illness that necessitated the hospitalization is successfully treated. In this article, we describe
risk factors and risk stratification tools that identify older adults at highest risk of
hospitalization-associated disability. We describe hospital processes that may promote
hospitalization-associated disability and models of care that have been developed to prevent it.
Since recognition of functional status problems is an essential prerequisite to preventing and
managing disability, we also describe a pragmatic approach toward functional status assessment in
the hospital focused on evaluation of ADLs, mobility, and cognition. Based on studies of acute
geriatric units, we describe interventions hospitals and clinicians can consider to prevent
hospitalization-associated disability in patients. Finally, we describe approaches clinicians can
implement to improve the quality of life of older adults who develop hospitalization-associated
disability and that of their caregivers. JAMA. 2011;306(16):1782-1793
文献类型: Article
KeyWords Plus: PREDICTS FUNCTIONAL DECLINE; ACUTE MEDICAL ILLNESS; ILL
OLDER PATIENTS; LONG-TERM-CARE; RANDOMIZED-TRIAL; LOW MOBILITY;
MULTICOMPONENT INTERVENTION; GERIATRIC ASSESSMENT; RESTRICTED
ACTIVITY; ELDERLY PATIENTS
地址: [Covinsky, Kenneth E.; Pierluissi, Edgar; Johnston, C. Bree] Univ Calif San Francisco, Div
Geriatr, San Francisco, CA 94121 USA.
[Covinsky, Kenneth E.; Pierluissi, Edgar; Johnston, C. Bree] Univ Calif San Francisco, Dept Med,
San Francisco, CA 94121 USA.
[Pierluissi, Edgar] San Francisco Gen Hosp, Dept Med, San Francisco, CA 94110 USA.
[Pierluissi, Edgar] San Francisco Gen Hosp, Div Hosp Med, San Francisco, CA 94110 USA.
[Covinsky, Kenneth E.; Johnston, C. Bree] San Francisco VA Med Ctr, Sect Geriatr & Palliat Care,
San Francisco, CA USA.
通讯作者地址: Covinsky, KE (通讯作者),Univ Calif San Francisco, Div Geriatr, 4150 Clement
St 181G, San Francisco, CA 94121 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 12
第 33 条，共 81 条
标题: Aging with multimorbidity: A systematic review of the literature
作者: Marengoni, A (Marengoni, Alessandra); Angleman, S (Angleman, Sara); Melis, R (Melis,
Rene); Mangialasche, F (Mangialasche, Francesca); Karp, A (Karp, Anita); Garmen, A (Garmen,
Annika); Meinow, B (Meinow, Bettina); Fratiglioni, L (Fratiglioni, Laura)
来 源 出 版 物 : AGEING RESEARCH REVIEWS 卷 : 10 期 : 4 页 : 430-439 DOI:
10.1016/j.arr.2011.03.003 出版年: SEP 2011
Web of Science 核心合集中的 "被引频次": 253
被引频次合计: 259
引用的参考文献数: 76
摘要: A literature search was carried out to summarize the existing scientific evidence concerning
occurrence, causes, and consequences of multimorbidity (the coexistence of multiple chronic
diseases) in the elderly as well as models and quality of care of persons with multimorbidity.
According to pre-established inclusion criteria, and using different search strategies, 41 articles
were included (four of these were methodological papers only). Prevalence of multimorbidity in
older persons ranges from 55 to 98%. In cross-sectional studies, older age, female gender, and low
socioeconomic status are factors associated with multimorbidity, confirmed by longitudinal
studies as well. Major consequences of multimorbidity are disability and functional decline, poor
quality of life, and high health care costs. Controversial results were found on multimorbidity and
mortality risk. Methodological issues in evaluating multimorbidity are discussed as well as future
research needs, especially concerning etiological factors, combinations and clustering of chronic
diseases, and care models for persons affected by multiple disorders. New insights in this field can
lead to the identification of preventive strategies and better treatment of multimorbid patients. (C)
2011 Elsevier B.V. All rights reserved.
文献类型: Review
作者关键词: Aging; Chronic diseases; Multimorbidity; Prevalence; Incidence; Risk factors;
Consequences; Quality of care
KeyWords Plus: MULTIPLE CHRONIC CONDITIONS; PRIMARY-CARE; CHRONIC
DISEASES; GENERAL-PRACTICE; OLDER-ADULTS; ELDERLY POPULATION;
RESEARCH AGENDA; CO-MORBIDITY; HEALTH-CARE; PREVALENCE
地址: [Angleman, Sara] Univ Brescia, Dept Med & Surg Sci, Geriatr Unit, I-25123 Brescia, Italy.
[Marengoni, Alessandra; Angleman, Sara; Melis, Rene; Mangialasche, Francesca; Karp, Anita;
Garmen, Annika; Meinow, Bettina; Fratiglioni, Laura] Karolinska Inst, NVS Dept, Aging Res Ctr,
S-10401 Stockholm, Sweden.
[Marengoni, Alessandra; Angleman, Sara; Melis, Rene; Mangialasche, Francesca; Karp, Anita;
Garmen, Annika; Meinow, Bettina; Fratiglioni, Laura] Stockholm Univ, Stockholm, Sweden.
[Melis, Rene] Radboud Univ Nijmegen, Med Ctr, Nijmegen Alzheimer Ctr, NL-6525 ED
Nijmegen, Netherlands.
[Mangialasche, Francesca] Univ Perugia, Dept Clin & Expt Med, Inst Gerontol & Geriatr, I-06100
Perugia, Italy.
[Karp, Anita; Garmen, Annika; Meinow, Bettina; Fratiglioni, Laura] Stockholm Gerontol Res Ctr,
Stockholm, Sweden.
通讯作者地址: Marengoni, A (通讯作者),Univ Brescia, Dept Med & Surg Sci, Div Internal Med
1, Spedali Civili, Piazzale Spedali Civili 1, I-25123 Brescia, Italy.
电子邮件地址: [email protected]
来源出版物页码计数: 10
第 34 条，共 81 条
标题: Health Care Utilization and Costs of Elderly Persons With Multiple Chronic Conditions
作者: Lehnert, T (Lehnert, Thomas); Heider, D (Heider, Dirk); Leicht, H (Leicht, Hanna);
Heinrich, S (Heinrich, Sven); Corrieri, S (Corrieri, Sandro); Luppa, M (Luppa, Melanie);
Riedel-Heller, S (Riedel-Heller, Steffi); Konig, HH (Koenig, Hans-Helmut)
来源出版物: MEDICAL CARE RESEARCH AND REVIEW 卷: 68 期: 4 页: 387-420 DOI:
10.1177/1077558711399580 出版年: AUG 2011
Web of Science 核心合集中的 "被引频次": 83
被引频次合计: 83
引用的参考文献数: 116
摘要: This systematic literature review identified and summarized 35 studies that investigated the
relationship between multiple chronic conditions (MCCs) and health care utilization outcomes
(i.e. physician use, hospital use, medication use) and health care cost outcomes (medication costs,
out-of-pocket costs, total health care costs) for elderly general populations. Although synthesis of
studies was complicated because of ambiguous definitions and measurements of MCCs, and
because of the multitude of outcomes investigated, almost all studies observed a positive
association of MCCs and use/costs, many of which found that use/costs significantly increased
with each additional condition. Several studies indicate a curvilinear, near exponential relationship
between MCCs and costs. The rising prevalence, substantial costs, and the fear that current care
arrangements may be inappropriate for many patients with MCCs, bring about a multitude of
implications for research and policy, of which the most important are presented and discussed.
文献类型: Review
作者关键词: multiple chronic conditions; multimorbidity; health care utilization; health care
costs; aged
KeyWords Plus: INAPPROPRIATE MEDICATION USE; CLINICAL COMORBIDITY INDEX;
MULTIMORBID OLDER-ADULTS; PRESCRIPTION DRUG-USE; QUALITY-OF-LIFE;
CHRONIC DISEASES; UNITED-STATES; CHRONIC ILLNESS; HOSPITAL READMISSION;
SERVICES RESEARCH
地址: [Lehnert, Thomas] Univ Med Ctr Hamburg Eppendorf, Dept Med Sociol & Hlth Econ
IMSG, D-04103 Leipzig, Germany.
[Heider, Dirk; Corrieri, Sandro; Luppa, Melanie; Riedel-Heller, Steffi] Univ Leipzig, Leipzig,
Germany.
通讯作者地址: Lehnert, T (通讯作者),Univ Med Ctr Hamburg Eppendorf, Dept Med Sociol &
Hlth Econ IMSG, Martinistr 52, D-04103 Leipzig, Germany.
电子邮件地址: [email protected]
来源出版物页码计数: 34
第 35 条，共 81 条
标题: Freezing of gait: moving forward on a mysterious clinical phenomenon
作者: Nutt, JG (Nutt, John G.); Bloem, BR (Bloem, Bastiaan R.); Giladi, N (Giladi, Nir); Hallett,
M (Hallett, Mark); Horak, FB (Horak, Fay B.); Nieuwboer, A (Nieuwboer, Alice)
来源出版物: LANCET NEUROLOGY 卷: 10 期: 8 页: 734-744 出版年: AUG 2011
Web of Science 核心合集中的 "被引频次": 185
被引频次合计: 189
引用的参考文献数: 110
摘要: Freezing of gait (FoG) is a unique and disabling clinical phenomenon characterised by brief
episodes of inability to step or by extremely short steps that typically occur on initiating gait or on
turning while walking. Patients with FoG, which is a feature of parldnsonian syndromes, show
variability in gait metrics between FoG episodes and a substantial reduction in step length with
frequent trembling of the legs during FoG episodes. Physiological, functional imaging, and
clinical pathological studies point to disturbances in frontal cortical regions, the basal ganglia, and
the midbrain locomotor region as the probable origins of FoG. Medications, deep brain
stimulation, and rehabilitation techniques can alleviate symptoms of FoG in some patients, but
these treatments lack efficacy in patients with advanced FoG. A better understanding of the
phenomenon is needed to aid the development of effective therapeutic strategies.
文献类型: Review
KeyWords Plus: ANTICIPATORY POSTURAL ADJUSTMENTS; SUBTHALAMIC NUCLEUS
STIMULATION;
PARKINSONS-DISEASE
PATIENTS;
QUALITY-OF-LIFE;
PEDUNCULOPONTINE NUCLEUS; AUDITORY CUES; BILATERAL COORDINATION;
BASAL GANGLIA; OLDER-ADULTS; BRAIN-STEM
地址: [Nutt, John G.; Horak, Fay B.] Oregon Hlth & Sci Univ, Dept Neurol, Portland, OR 97239
USA.
[Bloem, Bastiaan R.] Radboud Univ Nijmegen, Med Ctr, Donders Inst Brain Cognit & Behav,
NL-6525 ED Nijmegen, Netherlands.
[Giladi, Nir] Tel Aviv Univ, Tel Aviv Sourasky Med Ctr, Sackler Sch Med, IL-69978 Tel Aviv,
Israel.
[Hallett, Mark] Natl Inst Neurol Disorders & Stroke, Bethesda, MD USA.
[Nieuwboer, Alice] Katholieke Univ Leuven, Dept Rehabil Sci, Tervuursevest, Belgium.
通讯作者地址: Nutt, JG (通讯作者),Oregon Hlth & Sci Univ, Dept Neurol, Portland, OR 97239
USA.
电子邮件地址: [email protected]
来源出版物页码计数: 11
第 36 条，共 81 条
标题: How many steps/day are enough? For older adults and special populations
作者: Tudor-Locke, C (Tudor-Locke, Catrine); Craig, CL (Craig, Cora L.); Aoyagi, Y (Aoyagi,
Yukitoshi); Bell, RC (Bell, Rhonda C.); Croteau, KA (Croteau, Karen A.); De Bourdeaudhuij, I
(De Bourdeaudhuij, Ilse); Ewald, B (Ewald, Ben); Gardner, AW (Gardner, Andrew W.); Hatano, Y
(Hatano, Yoshiro); Lutes, LD (Lutes, Lesley D.); Matsudo, SM (Matsudo, Sandra M.);
Ramirez-Marrero, FA (Ramirez-Marrero, Farah A.); Rogers, LQ (Rogers, Laura Q.); Rowe, DA
(Rowe, David A.); Schmidt, MD (Schmidt, Michael D.); Tully, MA (Tully, Mark A.); Blair, SN
(Blair, Steven N.)
来源出版物: INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL
ACTIVITY 卷: 8 文献号: 80 DOI: 10.1186/1479-5868-8-80 出版年: JUL 28 2011
Web of Science 核心合集中的 "被引频次": 115
被引频次合计: 116
引用的参考文献数: 120
摘要: Older adults and special populations (living with disability and/or chronic illness that may
limit mobility and/or physical endurance) can benefit from practicing a more physically active
lifestyle, typically by increasing ambulatory activity. Step counting devices (accelerometers and
pedometers) offer an opportunity to monitor daily ambulatory activity; however, an appropriate
translation of public health guidelines in terms of steps/day is unknown. Therefore this review was
conducted to translate public health recommendations in terms of steps/day. Normative data
indicates that 1) healthy older adults average 2,000-9,000 steps/day, and 2) special populations
average 1,200-8,800 steps/day. Pedometer-based interventions in older adults and special
populations elicit a weighted increase of approximately 775 steps/day (or an effect size of 0.26)
and 2,215 steps/day (or an effect size of 0.67), respectively. There is no evidence to inform a
moderate intensity cadence (i.e., steps/minute) in older adults at this time. However, using the
adult cadence of 100 steps/minute to demark the lower end of an absolutely-defined moderate
intensity (i.e., 3 METs), and multiplying this by 30 minutes produces a reasonable heuristic (i.e.,
guiding) value of 3,000 steps. However, this cadence may be unattainable in some frail/diseased
populations. Regardless, to truly translate public health guidelines, these steps should be taken
over and above activities performed in the course of daily living, be of at least moderate intensity
accumulated in minimally 10 minute bouts, and add up to at least 150 minutes over the week.
Considering a daily background of 5,000 steps/day (which may actually be too high for some
older adults and/or special populations), a computed translation approximates 8,000 steps on days
that include a target of achieving 30 minutes of moderate-to-vigorous physical activity (MVPA),
and approximately 7,100 steps/day if averaged over a week. Measured directly and including these
background activities, the evidence suggests that 30 minutes of daily MVPA accumulated in
addition to habitual daily activities in healthy older adults is equivalent to taking approximately
7,000-10,000 steps/day. Those living with disability and/or chronic illness (that limits mobility and
or/physical endurance) display lower levels of background daily activity, and this will affect
whole-day estimates of recommended physical activity.
文献类型: Review
KeyWords
Plus:
PHYSICAL-ACTIVITY
INTERVENTION;
RANDOMIZED
CONTROLLED-TRIAL;
BREAST-CANCER
SURVIVORS;
QUALITY-OF-LIFE;
PERIPHERAL ARTERIAL-DISEASE; TYPE-2 DIABETES MANAGEMENT; 1ST STEP
PROGRAM; AMBULATORY ACTIVITY; WALKING INTERVENTION; JAPANESE ADULTS
地址: [Tudor-Locke, Catrine] Pennington Biomed Res Ctr, Walking Behav Lab, Baton Rouge, LA
70808 USA.
[Tudor-Locke, Catrine; Craig, Cora L.] Canadian Fitness & Lifestyle Res Inst, W Ottawa, ON
K2P 0J2, Canada.
[Craig, Cora L.] Univ Sydney, Sch Publ Hlth, Sydney, NSW 2006, Australia.
[Aoyagi, Yukitoshi] Tokyo Metropolitan Inst Gerontol, Exercise Sci Res Grp, Tokyo 173, Japan.
[Bell, Rhonda C.] Univ Alberta, Dept Agr Food & Nutr Sci, Agr Forestry Ctr 4 10, Edmonton, AB
T6G 2P5, Canada.
[Croteau, Karen A.] Univ So Maine, Dept Exercise Hlth & Sport Sci, Gorham, ME USA.
[De Bourdeaudhuij, Ilse] Univ Ghent, Dept Movement & Sport Sci, B-9000 Ghent, Belgium.
[Ewald, Ben] Univ Newcastle, Ctr Clin Epidemiol & Biostat, Callaghan, NSW 2308, Australia.
[Gardner, Andrew W.] Univ Oklahoma, Hlth Sci Ctr, CMRI Diabet & Metab Res Program, Harold
Hamm Oklahoma Diabet Ctr, Oklahoma City, OK USA.
[Hatano, Yoshiro] Tokyo Gakugei Univ, Tokyo 1848501, Japan.
[Lutes, Lesley D.] E Carolina Univ, Dept Psychol, Greenville, NC 27858 USA.
[Matsudo, Sandra M.] Ctr Estudos Lab Aptidao Fis Sao Caetana Sul CELAF, Sao Caetano do Sul,
Brazil.
[Matsudo, Sandra M.; Rogers, Laura Q.] So Illinois Univ, Sch Med, Dept Med, Springfield, IL
62708 USA.
[Ramirez-Marrero, Farah A.] Univ Puerto Rico, Dept Phys Educ & Recreat, San Juan, PR USA.
[Rowe, David A.] Univ Strathclyde, Sch Psychol Sci & Hlth, Glasgow, Lanark, Scotland.
[Schmidt, Michael D.] Univ Georgia, Dept Kinesiol, Athens, GA 30602 USA.
[Schmidt, Michael D.] Univ Tasmania, Menzies Res Inst, Hobart, Tas 7000, Australia.
[Tully, Mark A.] Queens Univ, UKCRC Ctr Publ Hlth NI, Belfast, Antrim, North Ireland.
[Blair, Steven N.] Univ S Carolina, Dept Exercise Sci & Epidemiol Biostat, Arnold Sch Publ Hlth,
Columbia, SC 29208 USA.
通讯作者地址: Tudor-Locke, C (通讯作者),Pennington Biomed Res Ctr, Walking Behav Lab,
Baton Rouge, LA 70808 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 19
第 37 条，共 81 条
标题: Low Health Literacy and Health Outcomes: An Updated Systematic Review
作者: Berkman, ND (Berkman, Nancy D.); Sheridan, SL (Sheridan, Stacey L.); Donahue, KE
(Donahue, Katrina E.); Halpern, DJ (Halpern, David J.); Crotty, K (Crotty, Karen)
来 源 出 版 物 : ANNALS OF INTERNAL MEDICINE 卷 : 155 期 : 2 页 : 97-+ DOI:
10.7326/0003-4819-155-2-201107190-00005 出版年: JUL 19 2011
Web of Science 核心合集中的 "被引频次": 443
被引频次合计: 449
引用的参考文献数: 0
摘要: Background: Approximately 80 million Americans have limited health literacy, which puts
them at greater risk for poorer access to care and poorer health outcomes.
Purpose: To update a 2004 systematic review and determine whether low health literacy is related
to poorer use of health care, outcomes, costs, and disparities in health outcomes among persons of
all ages.
Data Sources: English-language articles identified through MEDLINE, CINAHL, PsycINFO,
ERIC, and Cochrane Library databases and hand-searching (search dates for articles on health
literacy, 2003 to 22 February 2011; for articles on numeracy, 1966 to 22 February 2011).
Study Selection: Two reviewers independently selected studies that compared outcomes by
differences in directly measured health literacy or numeracy levels.
Data Extraction: One reviewer abstracted article information into evidence tables; a second
reviewer checked information for accuracy. Two reviewers independently rated study quality by
using predefined criteria, and the investigative team jointly graded the overall strength of
evidence.
Data Synthesis: 96 relevant good-or fair-quality studies in 111 articles were identified: 98 articles
on health literacy, 22 on numeracy, and 9 on both. Low health literacy was consistently associated
with more hospitalizations; greater use of emergency care; lower receipt of mammography
screening and influenza vaccine; poorer ability to demonstrate taking medications appropriately;
poorer ability to interpret labels and health messages; and, among elderly persons, poorer overall
health status and higher mortality rates. Poor health literacy partially explains racial disparities in
some outcomes. Reviewers could not reach firm conclusions about the relationship between
numeracy and health outcomes because of few studies or inconsistent results among studies.
Limitations: Searches were limited to articles published in English. No Medical Subject Heading
terms exist for identifying relevant studies. No evidence concerning oral health literacy (speaking
and listening skills) and outcomes was found.
Conclusion: Low health literacy is associated with poorer health outcomes and poorer use of
health care services.
文献类型: Review
KeyWords Plus: QUALITY-OF-LIFE; HIV MEDICATION ADHERENCE; MANAGED CARE
ENROLLEES; OLDER-ADULTS; RACIAL-DIFFERENCES; GLYCEMIC CONTROL;
NUMERACY SKILLS; HEART-FAILURE; ANTIRETROVIRAL ADHERENCE; SCREENING
MAMMOGRAPHY
地址: [Berkman, Nancy D.] RTI Int, Div Hlth Serv & Social Policy Res, Program Hlth Care Qual
& Outcomes, Res Triangle Pk, NC 27709 USA.
Univ N Carolina, Chapel Hill, NC USA.
Duke Univ, Durham, NC USA.
通讯作者地址: Berkman, ND (通讯作者),RTI Int, Div Hlth Serv & Social Policy Res, Program
Hlth Care Qual & Outcomes, POB 12194,3040 Cornwallis Rd, Res Triangle Pk, NC 27709 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 19
第 38 条，共 81 条
标题: Hearing Loss Prevalence and Risk Factors Among Older Adults in the United States
作者: Lin, FR (Lin, Frank R.); Thorpe, R (Thorpe, Roland); Gordon-Salant, S (Gordon-Salant,
Sandra); Ferrucci, L (Ferrucci, Luigi)
来源出版物: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND
MEDICAL SCIENCES 卷: 66 期: 5 页: 582-590 DOI: 10.1093/gerona/glr002 出版年: MAY
2011
Web of Science 核心合集中的 "被引频次": 110
被引频次合计: 113
引用的参考文献数: 39
摘要: Background. Hearing loss has been associated with cognitive and functional decline in older
adults and may be amenable to rehabilitative interventions, but national estimates of hearing loss
prevalence and hearing aid use in older adults are unavailable.
Methods. We analyzed data from the 2005-2006 cycle of the National Health and Nutritional
Examination Survey, which is the first cycle to ever incorporate hearing assessment in adults aged
70 years and older. Audiometry was performed in 717 older adults, and data on hearing aid use,
noise exposure, medical history, and demographics were obtained from interviews. Analyses
incorporated sampling weights to account for the complex sampling design and yield results that
are generalizable to the U.S. population.
Results. The prevalence of hearing loss defined as a speech frequency pure tone average of more
than 25 dB in the better ear was 63.1% (95% confidence interval: 57.4-68.8). Age, sex, and race
were the factors most strongly associated with hearing loss after multivariate adjustment, with
black race being substantially protective against hearing loss (odds ratio 0.32 compared with white
participants [95% confidence interval: 0.19-0.53]). Hearing aids were used in 40.0% (95%
confidence interval: 35.1-44.8) of adults with moderate hearing loss, but in only 3.4% (95%
confidence interval: 0.8-6.0) of those with a mild hearing loss.
Conclusion. Hearing loss is prevalent in nearly two thirds of adults aged 70 years and older in the
U.S. population. Additional research is needed to determine the epidemiological and physiological
basis for the protective effect of black race against hearing loss and to determine the role of
hearing aids in those with a mild hearing loss.
文献类型: Article
作者关键词: Hearing loss; Epidemiology; Older adults; Risk factors; Race; Hearing aids
KeyWords Plus: QUALITY-OF-LIFE; FRAMINGHAM COHORT; STRIA VASCULARIS;
IMPAIRMENT; HEALTH; AGE; EPIDEMIOLOGY; ASSOCIATION; PREDICTOR; DISEASE
地址: [Lin, Frank R.] Johns Hopkins Sch Med, Dept Otolaryngol Head & Neck Surg, Baltimore,
MD USA.
[Lin, Frank R.] Johns Hopkins Med Inst, Ctr Aging & Hlth, Baltimore, MD 21205 USA.
[Thorpe, Roland] Johns Hopkins Bloomberg Sch Publ Hlth, Johns Hopkins Ctr Hlth Dispar Solut,
Baltimore, MD USA.
[Thorpe, Roland] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Hlth Policy & Management,
Baltimore, MD USA.
[Gordon-Salant, Sandra] Univ Maryland, Dept Hearing & Speech Sci, College Pk, MD 20742
USA.
[Ferrucci, Luigi] NIA, Longitudinal Studies Sect, Clin Res Branch, Baltimore, MD 21224 USA.
通讯作者地址: Lin, FR (通讯作者),Johns Hopkins Ctr Aging & Health, 2024 E Monument
St,Suite 2-700, Baltimore, MD 21287 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 9
第 39 条，共 81 条
标题: Effect of Exercise on Cognitive Performance in Community-Dwelling Older Adults:
Review of Intervention Trials and Recommendations for Public Health Practice and Research
作者: Snowden, M (Snowden, Mark); Steinman, L (Steinman, Lesley); Mochan, K (Mochan,
Kara); Grodstein, F (Grodstein, Francine); Prohaska, TR (Prohaska, Thomas R.); Thurman, DJ
(Thurman, David J.); Brown, DR (Brown, David R.); Laditka, JN (Laditka, James N.); Soares, J
(Soares, Jesus); Zweiback, DJ (Zweiback, Damita J.); Little, D (Little, Deborah); Anderson, LA
(Anderson, Lynda A.)
来源出版物: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 卷: 59 期: 4 页:
704-716 DOI: 10.1111/j.1532-5415.2011.03323.x 出版年: APR 2011
Web of Science 核心合集中的 "被引频次": 61
被引频次合计: 61
引用的参考文献数: 50
摘要: There is evidence from observational studies that increasing physical activity may reduce
the risk of cognitive decline in older adults. Exercise intervention trials have found conflicting
results. A systematic review of physical activity and exercise intervention trials on cognition in
older adults was conducted. Six scientific databases and reference lists of previous reviews were
searched. Thirty studies were eligible for inclusion. Articles were grouped into
intervention-outcome pairings. Interventions were grouped as cardiorespiratory, strength, and
multicomponent exercises. Cognitive outcomes were general cognition, executive function,
memory, reaction time, attention, cognitive processing, visuospatial, and language. An
eight-member multidisciplinary panel rated the quality and effectiveness of each pairing. Although
there were some positive studies, the panel did not find sufficient evidence that physical activity or
exercise improved cognition in older adults. Future research should report exercise adherence, use
longer study durations, and determine the clinical relevance of measures used.
文献类型: Article
作者关键词: exercise; physical activity; cognition; older adults; review
KeyWords Plus: QUALITY-OF-LIFE; AEROBIC EXERCISE; PHYSICAL-ACTIVITY;
REACTION-TIME; WOMEN; PROGRAM; DECLINE; MEMORY; POPULATION;
IMPAIRMENT
地址: [Snowden, Mark] Univ Washington, Sch Med, Dept Psychiat & Behav Sci, Seattle, WA
98104 USA.
[Steinman, Lesley] Univ Washington, Hlth Promot Res Ctr, Seattle, WA 98104 USA.
[Mochan, Kara] Univ Washington, Sch Nursing, Seattle, WA 98104 USA.
[Grodstein, Francine] Brigham & Womens Hosp, Boston, MA 02115 USA.
[Grodstein, Francine] Harvard Univ, Sch Med, Boston, MA USA.
[Prohaska, Thomas R.] Univ Illinois, Sch Publ Hlth, Inst Hlth Res & Policy, Chicago, IL USA.
[Brown, David R.; Soares, Jesus] Ctr Dis Control & Prevent, Phys Act & Hlth Branch, Div Nutr
Phys Act & Obes, Atlanta, GA USA.
[Thurman, David J.; Anderson, Lynda A.] Ctr Dis Control & Prevent, Natl Ctr Chron Dis Prevent
& Hlth Promot, Atlanta, GA USA.
[Laditka, James N.] Univ N Carolina, Dept Publ Hlth Sci, Charlotte, NC 28223 USA.
[Zweiback, Damita J.] Michigan Dept Community Hlth, Lansing, MI USA.
[Little, Deborah] Univ Illinois, Med Ctr, Ctr Stroke Res, Ctr Cognit Med, Chicago, IL USA.
[Anderson, Lynda A.] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA.
通讯作者地址: Snowden, M (通讯作者),Univ Washington, Sch Med, Dept Psychiat & Behav
Sci, Box 359911, Seattle, WA 98104 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 13
第 40 条，共 81 条
标题: Weight Loss, Exercise, or Both and Physical Function in Obese Older Adults
作者: Villareal, DT (Villareal, Dennis T.); Chode, S (Chode, Suresh); Parimi, N (Parimi, Nehu);
Sinacore, DR (Sinacore, David R.); Hilton, T (Hilton, Tiffany); Armamento-Villareal, R
(Armamento-Villareal, Reina); Napoli, N (Napoli, Nicola); Qualls, C (Qualls, Clifford); Shah, K
(Shah, Krupa)
来源出版物: NEW ENGLAND JOURNAL OF MEDICINE 卷: 364 期: 13 页: 1218-1229 出
版年: MAR 31 2011
Web of Science 核心合集中的 "被引频次": 227
被引频次合计: 237
引用的参考文献数: 41
摘要: BACKGROUND
Obesity exacerbates the age-related decline in physical function and causes frailty in older adults;
however, the appropriate treatment for obese older adults is controversial.
METHODS
In this 1-year, randomized, controlled trial, we evaluated the independent and combined effects of
weight loss and exercise in 107 adults who were 65 years of age or older and obese. Participants
were randomly assigned to a control group, a weight-management (diet) group, an exercise group,
or a weight-management-plus-exercise (diet-exercise) group. The primary outcome was the
change in score on the modified Physical Performance Test. Secondary outcomes included other
measures of frailty, body composition, bone mineral density, specific physical functions, and
quality of life.
RESULTS
A total of 93 participants (87%) completed the study. In the intention-to-treat analysis, the score
on the Physical Performance Test, in which higher scores indicate better physical status, increased
more in the diet-exercise group than in the diet group or the exercise group (increases from
baseline of 21% vs. 12% and 15%, respectively); the scores in all three of those groups increased
more than the scores in the control group (in which the score increased by 1%) (P<0.001 for the
between-group differences). Moreover, the peak oxygen consumption improved more in the
diet-exercise group than in the diet group or the exercise group (increases of 17% vs. 10% and
8%, respectively; P<0.001); the score on the Functional Status Questionnaire, in which higher
scores indicate better physical function, increased more in the diet-exercise group than in the diet
group (increase of 10% vs. 4%, P<0.001). Body weight decreased by 10% in the diet group and by
9% in the diet-exercise group, but did not decrease in the exercise group or the control group
(P<0.001). Lean body mass and bone mineral density at the hip decreased less in the diet-exercise
group than in the diet group (reductions of 3% and 1%, respectively, in the diet-exercise group vs.
reductions of 5% and 3%, respectively, in the diet group; P<0.05 for both comparisons). Strength,
balance, and gait improved consistently in the diet-exercise group (P<0.05 for all comparisons).
Adverse events included a small number of exercise-associated musculoskeletal injuries.
CONCLUSIONS
These findings suggest that a combination of weight loss and exercise provides greater
improvement in physical function than either intervention alone.
文献类型: Article
KeyWords Plus: NURSING-HOME ADMISSION; CALORIC RESTRICTION; KNEE
OSTEOARTHRITIS; CONTROLLED-TRIAL; US ADULTS; FRAILTY; WOMEN;
PERFORMANCE; HEALTH; ASSOCIATION
地址: [Villareal, Dennis T.; Chode, Suresh; Parimi, Nehu; Sinacore, David R.; Shah, Krupa]
Washington Univ, Sch Med, Div Geriatr & Nutr Sci, St Louis, MO USA.
[Sinacore, David R.; Hilton, Tiffany] Washington Univ, Sch Med, Program Phys Therapy, St
Louis, MO USA.
[Armamento-Villareal, Reina; Napoli, Nicola] Washington Univ, Sch Med, Div Bone & Mineral
Dis, St Louis, MO USA.
[Villareal, Dennis T.] New Mexico VA Hlth Care Syst, Sect Geriatr, Albuquerque, NM 87108
USA.
[Armamento-Villareal, Reina] New Mexico VA Hlth Care Syst, Endocrinol Sect, Albuquerque,
NM 87108 USA.
[Villareal, Dennis T.] Univ New Mexico, Sch Med, Div Geriatr, Albuquerque, NM 87131 USA.
[Armamento-Villareal, Reina] Univ New Mexico, Sch Med, Div Endocrinol, Albuquerque, NM
87131 USA.
[Qualls, Clifford] Univ New Mexico, Sch Med, Dept Math & Stat, Albuquerque, NM 87131 USA.
通讯作者地址: Villareal, DT (通讯作者),New Mexico VA Hlth Care Syst, Sect Geriatr, Geriatr
111K,1501 San Pedro Dr, Albuquerque, NM 87108 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 12
第 41 条，共 81 条
标题: Relationship between the physical environment and physical activity in older adults: A
systematic review
作者: Van Cauwenberg, J (Cauwenberg, Jelle Van); De Bourdeaudhuij, I (De Bourdeaudhuij, Ilse);
De Meester, F (De Meester, Femke); Van Dyck, D (Van Dyck, Delfien); Salmon, J (Salmon, Jo);
Clarys, P (Clarys, Peter); Deforche, B (Deforche, Benedicte)
来 源 出 版 物 : HEALTH & PLACE 卷 :
10.1016/j.healthplace.2010.11.010 出版年: MAR 2011
17
期 :
2
页 :
458-469
DOI:
Web of Science 核心合集中的 "被引频次": 97
被引频次合计: 98
引用的参考文献数: 81
摘要: Previous reviews on children, adolescents and adults have reported consistent relationships
between several physical environmental characteristics and physical activity (PA). This systematic
review aims to provide a comprehensive overview of the literature concerning the relationship
between the physical environment and PA in older adults. A systematic literature search resulted in
the inclusion of 31 articles. Results were inconsistent but most of the studied environmental
characteristics were reported not to be related to PA. More studies in different contexts utilizing
longitudinal designs, standardized, reliable and validated PA and environmental measurements and
investigating possible moderating effects are definitely warranted. (C) 2010 Elsevier Ltd. All
rights reserved.
文献类型: Review
作者关键词: Physical environment; Physical activity; Older adults; Review
KeyWords Plus: NEIGHBORHOOD BUILT ENVIRONMENT; QUALITY-OF-LIFE;
MULTILEVEL ANALYSIS;
WALKING
ACTIVITY;
OBJECTIVE
MEASURES;
UNITED-STATES; URBAN FORM; HEALTH; PEOPLE; POPULATION
地址: [Cauwenberg, Jelle Van; Clarys, Peter; Deforche, Benedicte] Vrije Univ Brussel, Fac Phys
Educ & Phys Therapy, Dept Human Biometry & Biomech, B-1050 Brussels, Belgium.
[Cauwenberg, Jelle Van; De Bourdeaudhuij, Ilse; De Meester, Femke; Van Dyck, Delfien;
Deforche, Benedicte] Univ Ghent, Fac Med & Hlth Sci, Dept Movement & Sport Sci, B-9000
Ghent, Belgium.
[Salmon, Jo] Deakin Univ, Sch Exercise & Nutr Sci, Burwood, Vic 3125, Australia.
通讯作者地址: Van Cauwenberg, J (通讯作者),Vrije Univ Brussel, Fac Phys Educ & Phys
Therapy, Dept Human Biometry & Biomech, Pl laan 2, B-1050 Brussels, Belgium.
电子邮件地址: [email protected]
来源出版物页码计数: 12
第 42 条，共 81 条
标 题 : Spouses, Adult Children, and Children-in-Law as Caregivers of Older Adults: A
Meta-Analytic Comparison
作者: Pinquart, M (Pinquart, Martin); Sorensen, S (Soerensen, Silvia)
来源出版物: PSYCHOLOGY AND AGING 卷: 26 期: 1 页: 1-14 DOI: 10.1037/a0021863 出
版年: MAR 2011
Web of Science 核心合集中的 "被引频次": 92
被引频次合计: 96
引用的参考文献数: 196
摘要: The present meta-analysis integrates the results from 168 empirical studies on differences
between caregiving spouses, adult children, and children-in-law. Spouses differ from children and
children-in-law significantly with regard to sociodemographic variables; also, they provide more
support but report fewer care recipient behavior problems. Spouse caregivers report more
depression symptoms, greater financial and physical burden, and lower levels of psychological
well-being. Higher levels of psychological distress among spouses are explained mostly-but not
completely-by higher levels of care provision. Few differences emerge between children and
children-in-law, but children-in-law perceive the relationship with the care recipient as less
positive and they report fewer uplifts of caregiving.
文献类型: Article
作 者关 键词 : caregiver burden; caregiving; children; children-in-law; psychological health;
spouses
KeyWords Plus: QUALITY-OF-LIFE; NURSING-HOME PLACEMENT; CARE INSURANCE
SYSTEM; FAMILY CAREGIVERS; ALZHEIMERS-DISEASE; INFORMAL CAREGIVERS;
DEPRESSIVE SYMPTOMS; DEMENTIA CAREGIVERS; DAUGHTER CAREGIVERS;
GENDER-DIFFERENCES
地址: [Pinquart, Martin] Univ Marburg, Dept Psychol, D-35032 Marburg, Germany.
[Soerensen, Silvia] Univ Rochester, Sch Med & Dent, Dept Psychiat, Rochester, NY 14627 USA.
通讯作者地址: Pinquart, M (通讯作者),Univ Marburg, Dept Psychol, Gutenbergstr 18, D-35032
Marburg, Germany.
电子邮件地址: [email protected]
来源出版物页码计数: 14
第 43 条，共 81 条
标题: A tune in "a minor" can "b major": A review of epidemiology, illness course, and public
health implications of subthreshold depression in older adults
作者: Meeks, TW (Meeks, Thomas W.); Vahia, IV (Vahia, Ipsit V.); Lavretsky, H (Lavretsky,
Helen); Kulkarni, G (Kulkarni, Ganesh); Jeste, DV (Jeste, Dilip V.)
来源出版物: JOURNAL OF AFFECTIVE DISORDERS 卷: 129 期: 1-3 页: 126-142 DOI:
10.1016/j.jad.2010.09.015 出版年: MAR 2011
Web of Science 核心合集中的 "被引频次": 93
被引频次合计: 95
引用的参考文献数: 138
摘要: Background: With emphasis on dimensional aspects of psychopathology in development of
the upcoming DSM-V, we systematically review data on epidemiology, illness course, risk factors
for, and consequences of late-life depressive syndromes not meeting DSM-IV-TR criteria for
major depression or dysthymia. We termed these syndromes subthreshold depression, including
minor depression and subsyndromal depression.
Methods: We searched PubMed (1980-Jan 2010) using the terms: subsyndromal depression,
subthreshold depression, and minor depression in combination with elderly, geriatric, older adult,
and late-life. Data were extracted from 181 studies of late-life subthreshold depression.
Results: In older adults subthreshold depression was generally at least 2-3 times more prevalent
(median community point prevalence 9.8%) than major depression. Prevalence of subthreshold
depression was lower in community settings versus primary care and highest in long-term care
settings. Approximately 8-10% of older persons with subthreshold depression developed major
depression per year. The course of late-life subthreshold depression was more favorable than that
of late-life major depression, but far from benign, with a median remission rate to non-depressed
status of only 27% after >= 1 year. Prominent risk factors included female gender, medical burden,
disability, and low social support; consequences included increased disability, greater healthcare
utilization, and increased suicidal ideation.
Limitations: Heterogeneity of the data, especially related to definitions of subthreshold depression
limit our ability to conduct meta-analysis.
Conclusions: The high prevalence and associated adverse health outcomes of late-life
subthreshold depression indicate the major public health significance of this condition and suggest
a need for further research on its neurobiology and treatment. Such efforts could potentially lead
to prevention of considerable morbidity for the growing number of older adults. (C) 2010 Elsevier
B.V. All rights reserved.
文献类型: Review
作者关键词: Subsyndromal depression; Minor depression; Major depression
KeyWords
Plus:
PRIMARY-CARE
PATIENTS;
LATE-LIFE
DEPRESSION;
QUALITY-OF-LIFE; SCHIZOPHRENIA SPECTRUM DISORDERS; SIGNIFICANT
NONMAJOR DEPRESSION; MILD COGNITIVE IMPAIRMENT; ELDERLY COMMUNITY
SAMPLE; CONGESTIVE-HEART-FAILURE; ONE-YEAR OUTCOMES; SUBSYNDROMAL
DEPRESSION
地址: [Jeste, Dilip V.] Univ Calif San Diego, Sam & Rose Stein Inst Res Aging, Dept Psychiat, La
Jolla, CA 92093 USA.
[Lavretsky, Helen] Univ Calif Los Angeles, Dept Psychiat, Los Angeles, CA USA.
[Kulkarni, Ganesh] San Diego State Univ, San Diego, CA 92182 USA.
通讯作者地址: Jeste, DV (通讯作者),Univ Calif San Diego, Sam & Rose Stein Inst Res Aging,
Dept Psychiat, 9500 Gilman Dr,0664, La Jolla, CA 92093 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 17
第 44 条，共 81 条
标题: Hearing Loss and Incident Dementia
作者: Lin, FR (Lin, Frank R.); Metter, EJ (Metter, E. Jeffrey); O'Brien, RJ (O'Brien, Richard J.);
Resnick, SM (Resnick, Susan M.); Zonderman, AB (Zonderman, Alan B.); Ferrucci, L (Ferrucci,
Luigi)
来 源 出 版 物 : ARCHIVES OF NEUROLOGY 卷 : 68 期 : 2 页 : 214-220 DOI:
10.1001/archneurol.2010.362 出版年: FEB 2011
Web of Science 核心合集中的 "被引频次": 132
被引频次合计: 146
引用的参考文献数: 44
摘要: Objective: To determine whether hearing loss is associated with incident all-cause dementia
and Alzheimer disease (AD).
Design: Prospective study of 639 individuals who underwent audiometric testing and were
dementia free in 1990 to 1994. Hearing loss was defined by a pure-tone average of hearing
thresholds at 0.5, 1, 2, and 4 kHz in the better-hearing ear (normal, < 25 dB [n=455]; mild loss,
25-40 dB [n=125]; moderate loss, 41-70 dB [n=53]; and severe loss, > 70 dB [n=6]). Diagnosis of
incident dementia was made by consensus diagnostic conference. Cox proportional hazards
models were used to model time to incident dementia according to severity of hearing loss and
were adjusted for age, sex, race, education, diabetes mellitus, smoking, and hypertension.
Setting: Baltimore Longitudinal Study of Aging.
Participants: Six hundred thirty-nine individuals aged 36 to 90 years.
Main Outcome Measure: Incident caces of all-cause dementia and AD until May 31, 2008.
Results: During a median follow-up of 11.9 years, 58 cases of incident all-cause dementia were
diagnosed, of which 37 cases were AD. The risk of incident all-cause dementia increased log
linearly with the severity of baseline hearing loss (1.27 per 10-dB loss; 95% confidence interval,
1.06-1.50). Compared with normal hearing, the hazard ratio (95% confidence interval) for incident
all-cause dementia was 1.89 (1.00-3.58) for mild hearing loss, 3.00 (1.43-6.30) for moderate
hearing loss, and 4.94 (1.09-22.40) for severe hearing loss. The risk of incident AD also increased
with baseline hearing loss (1.20 per 10 dB of hearing loss) but with a wider confidence interval
(0.94-1.53).
Conclusions: Hearing loss is independently associated with incident all-cause dementia. Whether
hearing loss is a marker for early-stage dementia or is actually a modifiable risk factor for
dementia deserves further study. Arch Neurol. 2011; 68(2):214-220
文献类型: Article
KeyWords Plus: QUALITY-OF-LIFE; ALZHEIMERS-DISEASE; OLDER-ADULTS;
COGNITIVE DECLINE; IMPAIRMENT; PREVALENCE; AGE; HEALTH; DYSFUNCTION;
POPULATION
地址: [Lin, Frank R.] Johns Hopkins Sch Med, Dept Otolaryngol Head & Neck Surg, Baltimore,
MD 21287 USA.
[Lin, Frank R.] Johns Hopkins Med Inst, Ctr Aging & Hlth, Baltimore, MD 21205 USA.
[Metter, E. Jeffrey; Ferrucci, Luigi] NIA, Longitudinal Studies Sect, Clin Res Branch, Baltimore,
MD 21224 USA.
[O'Brien, Richard J.] Johns Hopkins Bayview Med Ctr, Dept Neurol, Baltimore, MD USA.
[O'Brien, Richard J.] Johns Hopkins Bayview Med Ctr, Dept Med, Baltimore, MD USA.
[Resnick, Susan M.; Zonderman, Alan B.] NIA, Lab Behav Neurosci, Intramural Res Program,
Bethesda, MD 20892 USA.
通讯作者地址: Lin, FR (通讯作者),Johns Hopkins Sch Med, Dept Otolaryngol Head & Neck
Surg, JHOC 6120,601 N Caroline St, Baltimore, MD 21287 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 7
第 45 条，共 81 条
标题: Objective Light-Intensity Physical Activity Associations With Rated Health in Older Adults
作者: Buman, MP (Buman, Matthew P.); Hekler, EB (Hekler, Eric B.); Haskell, WL (Haskell,
William L.); Pruitt, L (Pruitt, Leslie); Conway, TL (Conway, Terry L.); Cain, KL (Cain, Kelli L.);
Sallis, JF (Sallis, James F.); Saelens, BE (Saelens, Brian E.); Frank, LD (Frank, Lawrence D.);
King, AC (King, Abby C.)
来源出版物: AMERICAN JOURNAL OF EPIDEMIOLOGY 卷: 172 期: 10 页: 1155-1165
DOI: 10.1093/aje/kwq249 出版年: NOV 15 2010
Web of Science 核心合集中的 "被引频次": 134
被引频次合计: 137
引用的参考文献数: 59
摘要: The extent to which light-intensity physical activity contributes to health in older adults is
not well known. The authors examined associations between physical activity across the intensity
spectrum (sedentary to vigorous) and health and well-being variables in older adults. Two 7-day
assessments of accelerometry from 2005 to 2007 were collected 6 months apart in the
observational Senior Neighborhood Quality of Life Study of adults aged > 65 years in Baltimore,
Maryland, and Seattle, Washington. Self-reported health and psychosocial variables (e. g.,
lower-extremity function, body weight, rated stress) were also collected. Physical activity based
on existing accelerometer thresholds for moderate/vigorous, high-light, low-light, and sedentary
categories were examined as correlates of physical health and psychosocial well-being in
mixed-effects regression models. Participants (N = 862) were 75.4 (standard deviation, 6.8) years
of age, 56% female, 71% white, and 58% overweight/obese. After adjustment for study covariates
and time spent in moderate/vigorous physical activity and sedentary behavior, low-light and
high-light physical activity were positively related to physical health (all P < 0.0001) and
well-being (all P < 0.001). Additionally, replacing 30 minutes/day of sedentary time with equal
amounts of low-light or high-light physical activity was associated with better physical health (all
P < 0.0001). Objectively measured light-intensity physical activity is associated with physical
health and well-being variables in older adults.
文献类型: Article
作者关键词: aged; epidemiologic measurements; motor activity; quality of life; sedentary
lifestyle
KeyWords Plus: LATE-LIFE FUNCTION; UNITED-STATES; DISABILITY INSTRUMENT;
COMPUTER-SCIENCE; STYLE INTERVENTION; PERCEIVED STRESS; METABOLIC
RISK; ACCELEROMETER; DEPRESSION; MORTALITY
地址: [Buman, Matthew P.; Hekler, Eric B.; Haskell, William L.; Pruitt, Leslie; King, Abby C.]
Stanford Univ, Sch Med, Dept Med, Stanford Prevent Res Ctr, Stanford, CA 94305 USA.
[Conway, Terry L.; Cain, Kelli L.; Sallis, James F.] San Diego State Univ, Dept Psychol, San
Diego, CA 92182 USA.
[Saelens, Brian E.] Univ Washington, Dept Pediat, Seattle, WA 98195 USA.
[Saelens, Brian E.] Seattle Childrens Hosp Res Inst, Seattle, WA USA.
[Frank, Lawrence D.] Univ British Columbia, Sch Community & Reg Planning, Vancouver, BC
V5Z 1M9, Canada.
通讯作者地址: Buman, MP (通讯作者),Stanford Univ, Sch Med, Dept Med, Stanford Prevent
Res Ctr, Med Sch Off Bldg,251 Campus Dr,MC 5411, Stanford, CA 94305 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 11
第 46 条，共 81 条
标题: Physical activity and functional limitations in older adults: a systematic review related to
Canada's Physical Activity Guidelines
作者: Paterson, DH (Paterson, Donald H.); Warburton, DER (Warburton, Darren E. R.)
来源出版物: INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL
ACTIVITY 卷: 7 文献号: 38 DOI: 10.1186/1479-5868-7-38 出版年: MAY 11 2010
Web of Science 核心合集中的 "被引频次": 89
被引频次合计: 92
引用的参考文献数: 146
摘要: Background: The purpose was to conduct systematic reviews of the relationship between
physical activity of healthy community-dwelling older (> 65 years) adults and outcomes of
functional limitations, disability, or loss of independence.
Methods: Prospective cohort studies with an outcome related to functional independence or to
cognitive function were searched, as well as exercise training interventions that reported a
functional outcome. Electronic database search strategies were used to identify citations which
were screened (title and abstract) for inclusion. Included articles were reviewed to complete
standardized data extraction tables, and assess study quality. An established system of assessing
the level and grade of evidence for recommendations was employed.
Results: Sixty-six studies met inclusion criteria for the relationship between physical activity and
functional independence, and 34 were included with a cognitive function outcome. Greater
physical activity of an aerobic nature (categorized by a variety of methods) was associated with
higher functional status (expressed by a host of outcome measures) in older age. For functional
independence, moderate (and high) levels of physical activity appeared effective in conferring a
reduced risk (odds ratio similar to 0.5) of functional limitations or disability. Limitation in higher
level performance outcomes was reduced (odds ratio similar to 0.5) with vigorous (or high)
activity with an apparent dose-response of moderate through to high activity. Exercise training
interventions (including aerobic and resistance) of older adults showed improvement in
physiological and functional measures, and suggestion of longer-term reduction in incidence of
mobility disability. A relatively high level of physical activity was related to better cognitive
function and reduced risk of developing dementia; however, there were mixed results of the
effects of exercise interventions on cognitive function indices.
Conclusions: There is a consistency of findings across studies and a range of outcome measures
related to functional independence; regular aerobic activity and short-term exercise programmes
confer a reduced risk of functional limitations and disability in older age. Although a precise
characterization of a minimal or effective physical activity dose to maintain functional
independence is difficult, it appears moderate to higher levels of activity are effective and there
may be a threshold of at least moderate activity for significant outcomes.
文献类型: Review
KeyWords Plus: QUALITY-OF-LIFE; INCIDENT MOBILITY LIMITATION; BODY-MASS
INDEX; WOMEN AGED 75; COGNITIVE FUNCTION; RISK-FACTORS; ELDERLY-MEN;
POSTMENOPAUSAL WOMEN; STYLE FACTORS; MUSCULOSKELETAL FITNESS
地址: [Paterson, Donald H.] Univ Western Ontario, Sch Kinesiol, London, ON, Canada.
[Paterson, Donald H.] Univ Western Ontario, Canadian Ctr Act & Aging, London, ON, Canada.
[Warburton, Darren E. R.] Univ British Columbia, Cardiovasc Physiol Rehabil Lab, Vancouver,
BC V5Z 1M9, Canada.
[Warburton, Darren E. R.] Univ British Columbia, Expt Med Programme, Vancouver, BC V5Z
1M9, Canada.
通讯作者地址: Paterson, DH (通讯作者),Univ Western Ontario, Sch Kinesiol, London, ON,
Canada.
电子邮件地址: [email protected]
来源出版物页码计数: 22
第 47 条，共 81 条
标题: Meta-analysis: Excess Mortality After Hip Fracture Among Older Women and Men
作者: Haentjens, P (Haentjens, Patrick); Magaziner, J (Magaziner, Jay); Colon-Emeric, CS
(Colon-Emeric, Cathleen S.); Vanderschueren, D (Vanderschueren, Dirk); Milisen, K (Milisen,
Koen); Velkeniers, B (Velkeniers, Brigitte); Boonen, S (Boonen, Steven)
来 源 出 版 物 : ANNALS OF INTERNAL MEDICINE 卷 : 152 期 : 6 页 : 380-+ DOI:
10.7326/0003-4819-152-6-201003160-00008 出版年: MAR 16 2010
Web of Science 核心合集中的 "被引频次": 266
被引频次合计: 274
引用的参考文献数: 78
摘要: Background: Although an increased risk for death after hip fracture is well established,
whether this excess mortality persists over time is unclear.
Purpose: To determine the magnitude and duration of excess mortality after hip fracture in older
men and women.
Data Sources: Electronic search of MEDLINE and EMBASE for English and non-English articles
from 1957 to May 2009 and manual search of article references.
Study Selection: Prospective cohort studies were selected by 2 independent reviewers. The studies
had to assess mortality in women ( 22 cohorts) or men ( 17 cohorts) aged 50 years or older with
hip fracture, carry out a life-table analysis, and display the survival curves of the hip fracture
group and age- and sex-matched control groups.
Data Extraction: Survival curve data and items relevant to study validity and generalizability were
independently extracted by 2 reviewers.
Data Synthesis: Time-to-event meta-analyses showed that the relative hazard for all-cause
mortality in the first 3 months after hip fracture was 5.75 (95% CI, 4.94 to 6.67) in women and
7.95 ( CI, 6.13 to 10.30) in men. Relative hazards decreased substantially over time but did not
return to rates seen in age- and sex-matched control groups. Through use of life-table methods,
investigators estimated that white women having a hip fracture at age 80 years have excess annual
mortality compared with white women of the same age without a fracture of 8%, 11%, 18%, and
22% at 1, 2, 5, and 10 years after injury, respectively. Men with a hip fracture at age 80 years have
excess annual mortality of 18%, 22%, 26%, and 20% at 1, 2, 5, and 10 years after injury,
respectively.
Limitations: Cohort studies varied, sometimes markedly, in size, duration of observation, selection
of control populations, ascertainment of death, and adjustment for comorbid conditions. Only
published data that displayed findings with survival curves were examined. Publication bias was
possible.
Conclusion: Older adults have a 5- to 8-fold increased risk for all-cause mortality during the first 3
months after hip fracture. Excess annual mortality persists over time for both women and men, but
at any given age, excess annual mortality after hip fracture is higher in men than in women.
文献类型: Review
KeyWords Plus: QUALITY-OF-LIFE; OSTEOPOROTIC FRACTURES; ELDERLY-WOMEN;
INTERVENTION THRESHOLDS; OBSERVATIONAL COHORT; GENDER-DIFFERENCES;
POST-FRACTURE; HEALTH-STATUS; FEMORAL-NECK; SURVIVAL
地址: Univ Ziekenhuis Brussel, Jette, Belgium.
Vrije Univ Brussel, Elsene, Belgium.
Katholieke Univ Leuven, Louvain, Belgium.
Belgian Ctr Evidence Based Med, Louvain, Belgium.
Univ Maryland, Baltimore, MD 21201 USA.
Duke Univ, Med Ctr, Durham, NC USA.
Durham Vet Affairs Med Ctr, Durham, NC USA.
通讯作者地址: Haentjens, P (通讯作者),Vrije Univ Brussel, Ctr Outcomes Res, Univ Ziekenhuis
Brussel, Laarbeeklaan 101, B-1090 Brussels, Belgium.
电子邮件地址: [email protected]
来源出版物页码计数: 19
第 48 条，共 81 条
标题: Frail Patients Are at Increased Risk for Mortality and Prolonged Institutional Care After
Cardiac Surgery
作者: Lee, DH (Lee, Dana H.); Buth, KJ (Buth, Karen J.); Martin, BJ (Martin, Billie-Jean); Yip,
AM (Yip, Alexandra M.); Hirsch, GM (Hirsch, Gregory M.)
来 源 出 版 物 : CIRCULATION 卷 : 121 期 :
10.1161/CIRCULATIONAHA.108.841437 出版年: MAR 2 2010
8
页 :
973-978
DOI:
Web of Science 核心合集中的 "被引频次": 142
被引频次合计: 145
引用的参考文献数: 26
摘要: Background-Frailty is an emerging concept in medicine yet to be explored as a risk factor in
cardiac surgery. Where elderly patients are increasingly referred for cardiac surgery, the
prevalence of a frail group among these is also on the rise. We assessed frailty as a risk factor for
adverse outcomes after cardiac surgery.
Methods and Results-Functional measures of frailty and clinical data were collected prospectively
for all cardiac surgery patients at a single center. Frailty was defined as any impairment in
activities of daily living (Katz index), ambulation, or a documented history of dementia. Of 3826
patients, 157 (4.1%) were frail. Frail patients were older, were more likely to be female, and had
risk factors for adverse surgical outcomes. By logistic regression, frailty was an independent
predictor of in-hospital mortality (odds ratio 1.8, 95% CI 1.1 to 3.0), as well as institutional
discharge (odds ratio 6.3, 95% CI 4.2 to 9.4). Frailty was an independent predictor of reduced
midterm survival (hazard ratio 1.5, 95% CI 1.1 to 2.2).
Conclusions-Frailty is a risk for postoperative complications and an independent predictor of
in-hospital mortality, institutional discharge, and reduced midterm survival. Frailty screening
improves risk assessment in cardiac surgery patients and may identify a subgroup of patients who
may benefit from innovative processes of care. (Circulation. 2010; 121: 973-978.)
文献类型: Article
作者关键词: frail elderly; outcomes research; cardiac surgery
KeyWords Plus: QUALITY-OF-LIFE; NONCARDIAC SURGERY; OLDER-ADULTS;
OCTOGENARIANS; COMPLICATIONS; OUTCOMES; DISABILITY; DISEASE; PEOPLE;
INDEX
地址: [Lee, Dana H.; Buth, Karen J.; Martin, Billie-Jean; Yip, Alexandra M.; Hirsch, Gregory M.]
Dalhousie Univ, Dept Surg, Div Cardiac Surg, Halifax, NS, Canada.
通讯作者地址: Hirsch, GM (通讯作者),Queen Elizabeth 2 Hlth Sci Ctr, 1796 Summer St,Room
2006, Halifax, NS B3H 3A7, Canada.
电子邮件地址: [email protected]
来源出版物页码计数: 6
第 49 条，共 81 条
标题: Association Between Acute Care and Critical Illness Hospitalization and Cognitive Function
in Older Adults
作者: Ehlenbach, WJ (Ehlenbach, William J.); Hough, CL (Hough, Catherine L.); Crane, PK
(Crane, Paul K.); Haneuse, SJPA (Haneuse, Sebastien J. P. A.); Carson, SS (Carson, Shannon S.);
Curtis, JR (Curtis, J. Randall); Larson, EB (Larson, Eric B.)
来源出版物: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 卷: 303 期:
8 页: 763-770 DOI: 10.1001/jama.2010.167 出版年: FEB 24 2010
Web of Science 核心合集中的 "被引频次": 149
被引频次合计: 150
引用的参考文献数: 46
摘要: Context Studies suggest that many survivors of critical illness experience long-term
cognitive impairment but have not included premorbid measures of cognitive functioning and
have not evaluated risk for dementia associated with critical illness.
Objectives To determine whether decline in cognitive function was greater among older
individuals who experienced acute care or critical illness hospitalizations relative to those not
hospitalized and to determine whether the risk for incident dementia differed by these exposures.
Design, Setting, and Participants Analysis of data from a prospective cohort study from 1994
through 2007 comprising 2929 individuals 65 years old and older without dementia at baseline
residing in the community in the Seattle area and belonging to the Group Health Cooperative.
Participants with 2 or more study visits were included, and those who had a hospitalization for a
diagnosis of primary brain injury were censored at the time of hospitalization. Individuals were
screened with the Cognitive Abilities Screening Instrument (CASI) (score range, 0-100) every 2
years at follow-up visits, and those with a score less than 86 underwent a clinical examination for
dementia.
Main Outcome Measures Score on the CASI at follow-up study visits and incident dementia
diagnosed in study participants, adjusted for baseline cognitive scores, age, and other risk factors.
Results During a mean (SD) follow-up of 6.1 (3.2) years, 1601 participants had no hospitalization,
1287 had 1 or more noncritical illness hospitalizations, and 41 had 1 or more critical illness
hospitalizations. The CASI score was assessed more than 45 days after discharge for 94.3% of
participants. Adjusted CASI scores averaged 1.01 points lower for visits following acute care
illness hospitalization compared with follow-up visits not following any hospitalization (95%
confidence interval [CI], -1.33 to -0.70; P<.001) and 2.14 points lower on average for visits
following critical illness hospitalization (95% CI, -4.24 to -0.03; P=.047). There were 146 cases of
dementia among those not hospitalized, 228 cases of dementia among those with 1 or more
noncritical illness hospitalizations, and 5 cases of dementia among those with 1 or more critical
illness hospitalizations. The adjusted hazard ratio for incident dementia was 1.4 following a
noncritical illness hospitalization (95% CI, 1.1 to 1.7; P=.001) and 2.3 following a critical illness
hospitalization (95% CI, 0.9 to 5.7; P=.09).
Conclusions Among a cohort of older adults without dementia at baseline, those who experienced
acute care hospitalization and critical illness hospitalization had a greater likelihood of cognitive
decline compared with those who had no hospitalization. Noncritical illness hospitalization was
significantly associated with the development of dementia. JAMA. 2010; 303(8): 763-770
文献类型: Article
KeyWords Plus: RESPIRATORY-DISTRESS-SYNDROME; QUALITY-OF-LIFE; ACUTE
LUNG INJURY; PEOPLE AGED 65; OUTCOMES; DYSFUNCTION; SURVIVORS;
DEMENTIA; EPIDEMIOLOGY; DISEASE
地址: [Ehlenbach, William J.] Dept Vet Affairs, Hlth Serv Res & Dev, Seattle, WA 98101 USA.
[Ehlenbach, William J.; Hough, Catherine L.; Crane, Paul K.; Curtis, J. Randall; Larson, Eric B.]
Univ Washington, Dept Med, Seattle, WA USA.
[Haneuse, Sebastien J. P. A.; Larson, Eric B.] Grp Hlth Res Inst, Seattle, WA USA.
[Carson, Shannon S.] Univ N Carolina, Div Pulm & Crit Care Med, Chapel Hill, NC USA.
通讯作者地址: Ehlenbach, WJ (通讯作者),Dept Vet Affairs, Hlth Serv Res & Dev, 1100 Olive
Way,Ste 1400, Seattle, WA 98101 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 8
第 50 条，共 81 条
标题: ANXIETY DISORDERS IN OLDER ADULTS: A COMPREHENSIVE REVIEW
作者: Wolitzky-Taylor, KB (Wolitzky-Taylor, Kate B.); Castriotta, N (Castriotta, Natalie); Lenze,
EJ (Lenze, Eric J.); Stanley, MA (Stanley, Melinda A.); Craske, MG (Craske, Michelle G.)
来源出版物: DEPRESSION AND ANXIETY 卷: 27 期: 2 页: 190-211 DOI: 10.1002/da.20653
出版年: FEB 2010
Web of Science 核心合集中的 "被引频次": 118
被引频次合计: 121
引用的参考文献数: 171
摘要: This review aims to address issues unique to older adults with anxiety disorders in order to
inform potential changes in the DSM-V Prevalence and symptom expression of anxiety disorders
in late life, as well as risk factors, comorbidity, cognitive decline, age of onset, and treatment
efficacy for older adults are reviewed. Overall, the current literature suggests: (a) anxiety disorders
are common among older age individuals, but less common than in younger adults; (b) overlap
exists between anxiety symptoms of younger and older adults, although there are some differences
as well as limitations to the assessment of symptoms among older adults, (c) anxiety disorders are
highly comorbid with depression in older adults; (d) anxiety disorders are highly comorbid with a
number of medical illnesses; (e) associations between cognitive decline and anxiety have been
observed; (f) late age of onset is infrequent; and (g) both pharmacotherapy and CBT have
demonstrated efficacy for older adults with anxiety. The implications of these findings are
discussed and recommendations for the DSM-V are provided, including extending the text section
on age-specific features of anxiety disorders in late life and providing information about the
complexities of diagnosing anxiety disorders in older adults. Depression and Anxiety 27:190-211,
2010. (C) 2010 Wiley-Liss, Inc.
文献类型: Review
作者关键词: late-life anxiety; DSM; generalized anxiety; prevalence; course
KeyWords Plus: POSTTRAUMATIC-STRESS-DISORDER; OBSESSIVE-COMPULSIVE
DISORDER;
COGNITIVE-BEHAVIORAL
THERAPY;
LATE-LIFE
ANXIETY;
OBSTRUCTIVE PULMONARY-DISEASE; MAJOR DEPRESSIVE DISORDER; DEMENTED
ELDERLY-PATIENTS; CORONARY-HEART-DISEASE; PRIMARY-CARE PATIENTS;
QUALITY-OF-LIFE
地址: [Wolitzky-Taylor, Kate B.; Castriotta, Natalie; Craske, Michelle G.] Univ Calif Los Angeles,
Dept Psychol, Los Angeles, CA 90024 USA.
[Craske, Michelle G.] Univ Calif Los Angeles, Dept Psychiat & Biobehav Sci, Los Angeles, CA
90024 USA.
[Stanley, Melinda A.] Baylor Coll Med, Houston Ctr Qual Care & Utilizat Studies, Menninger
Dept Psychiat & Behav Sci, Houston, TX 77030 USA.
[Lenze, Eric J.] Washington Univ, Dept Psychiat, St Louis, MO USA.
通讯作者地址: Craske, MG (通讯作者),Univ Calif Los Angeles, Dept Psychol, Los Angeles, CA
90024 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 22
第 51 条，共 81 条
标题: Combined Resistance and Aerobic Exercise Program Reverses Muscle Loss in Men
Undergoing Androgen Suppression Therapy for Prostate Cancer Without Bone Metastases: A
Randomized Controlled Trial
作者: Galvao, DA (Galvao, Daniel A.); Taaffe, DR (Taaffe, Dennis R.); Spry, N (Spry, Nigel);
Joseph, D (Joseph, David); Newton, RU (Newton, Robert U.)
来 源 出 版 物 : JOURNAL OF CLINICAL ONCOLOGY 卷 : 28 期 : 2 页 : 340-347 DOI:
10.1200/JCO.2009.23.2488 出版年: JAN 10 2010
Web of Science 核心合集中的 "被引频次": 153
被引频次合计: 160
引用的参考文献数: 43
摘要: Purpose
Androgen suppression therapy (AST) results in musculoskeletal toxicity that reduces physical
function and quality of life. This study examined the impact of a combined resistance and aerobic
exercise program as a countermeasure to these AST-related toxicities.
Patients and Methods
Between 2007 and 2008, 57 patients with prostate cancer undergoing AST (commenced >2
months prior) were randomly assigned to a program of resistance and aerobic exercise (n = 29) or
usual care (n = 28) for 12 weeks. Primary end points were whole body and regional lean mass.
Secondary end points were muscle strength and function, cardiorespiratory capacity, blood
biomarkers, and quality of life.
Results
Analysis of covariance was used to compare outcomes for groups at 12 weeks adjusted for
baseline values and potential confounders. Patients undergoing exercise showed an increase in
lean mass compared with usual care (total body, P = .047; upper limb, P < .001; lower limb, P
= .019) and similarly better muscle strength (P < .01), 6-meter walk time (P = .024), and 6-meter
backward walk time (P = .039). Exercise also improved several aspects of quality of life including
general health (P = .022) and reduced fatigue (P = .021) and decreased levels of C-reactive protein
(P = .008). There were no adverse events during the testing or exercise intervention program.
Conclusion
A relatively brief exposure to exercise significantly improved muscle mass, strength, physical
function, and balance in hypogonadal men compared with normal care. The exercise regimen was
well tolerated and could be recommended for patients undergoing AST as an effective
countermeasure to these common treatment-related adverse effects.
文献类型: Article
KeyWords Plus: QUALITY-OF-LIFE; DISTANCE CORRIDOR WALK; DEPRIVATION
THERAPY;
OLDER-ADULTS;
CARDIOVASCULAR-DISEASE;
PHYSICAL
PERFORMANCE; BODY-COMPOSITION; SERUM TESTOSTERONE; HORMONE
AGONISTS; SKELETAL-MUSCLE
地址: [Galvao, Daniel A.] Edith Cowan Univ, Sch Exercise Biomed & Hlth Sci, Joondalup, WA
6027, Australia.
Univ Western Australia, Fac Med, Nedlands, WA 6009, Australia.
Univ Queensland, Sch Human Movement Studies, Brisbane, Qld, Australia.
通讯作者地址: Galvao, DA (通讯作者),Edith Cowan Univ, Sch Exercise Biomed & Hlth Sci,
100 Joondalup Dr, Joondalup, WA 6027, Australia.
电子邮件地址: [email protected]
来源出版物页码计数: 8
第 52 条，共 81 条
标题: Loneliness and HIV-related stigma explain depression among older HIV-positive adults
作者: Grov, C (Grov, Christian); Golub, SA (Golub, Sarit A.); Parsons, JT (Parsons, Jeffrey T.);
Brennan, M (Brennan, Mark); Karpiak, SE (Karpiak, Stephen E.)
来 源 出 版 物 : AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF
AIDS/HIV 卷 : 22 期 : 5 页 : 630-639 文 献 号 : PII 922244810 DOI:
10.1080/09540120903280901 出版年: 2010
Web of Science 核心合集中的 "被引频次": 70
被引频次合计: 70
引用的参考文献数: 51
摘要: Advances in the treatment of HIV have resulted in a large growing population of older
adults with HIV. These aging adults face added social, psychological, and physical challenges
associated with the aging process. Correlations between depression, loneliness, health, and
HIV/AIDS-related stigma have been studied, but there is little evaluation of these associations
among HIV-positive adults over the age of 50. Data for these analyses were taken from the
Research on Older Adults with HIV study of 914 New York City-based HIV-positive men and
women over the age of 50. In total, 39.1% of participants exhibited symptoms of major depression
(CES-D23). Multivariate modeling successfully explained 42% of the variance in depression
which was significantly related to increased HIV-associated stigma, increased loneliness,
decreased cognitive functioning, reduced levels of energy, and being younger. These data
underscore the need for service providers and researchers to assert more aggressive and innovative
efforts to resolve both psychosocial and physical health issues that characterize the graying of the
AIDS epidemic in the USA. Data suggest that focusing efforts to reduce HIV-related stigma and
loneliness may have lasting effects in reducing major depressive symptoms and improving
perceived health.
文献类型: Article
作者关键词: older HIV-positive adults; depression; stigma; loneliness; perceived health
KeyWords Plus: QUALITY-OF-LIFE; MEDICAL OUTCOMES; SOCIAL SUPPORT;
UNITED-STATES; HEALTH SURVEY; INFECTED MEN; HAART ERA; MOS-HIV;
HIV/AIDS; SCALE
地址: [Grov, Christian] CUNY Brooklyn Coll, Dept Hlth & Nutr Sci, Brooklyn, NY 11210 USA.
[Grov, Christian; Golub, Sarit A.; Parsons, Jeffrey T.] Ctr HIV AIDS Educ Studies & Training
CHEST, New York, NY USA.
[Golub, Sarit A.; Parsons, Jeffrey T.] CUNY, Grad Ctr, Dept Social & Personal Psychol, New
York, NY USA.
[Golub, Sarit A.; Parsons, Jeffrey T.] CUNY Hunter Coll, Dept Psychol, New York, NY 10021
USA.
[Brennan, Mark; Karpiak, Stephen E.] ACRIA, New York, NY USA.
通讯作者地址: Grov, C (通讯作者),CUNY Brooklyn Coll, Dept Hlth & Nutr Sci, Brooklyn, NY
11210 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 10
第 53 条，共 81 条
标题: A Motivational Theory of Life-Span Development
作者: Heckhausen, J (Heckhausen, Jutta); Wrosch, C (Wrosch, Carsten); Schulz, R (Schulz,
Richard)
来源出版物: PSYCHOLOGICAL REVIEW 卷: 117 期: 1 页: 32-60 DOI: 10.1037/a0017668
出版年: JAN 2010
Web of Science 核心合集中的 "被引频次": 280
被引频次合计: 285
引用的参考文献数: 213
摘要: This article had four goals. First, the authors identified a set of general challenges and
questions that a life-span theory of development should address. Second, they presented a
comprehensive account of their Motivational Theory of Life-Span Development. They integrated
the model of optimization in primary and secondary control and the action-phase model of
developmental regulation with their original fife-span theory of control to present a
comprehensive theory of development. Third, they reviewed the relevant empirical literature
testing key propositions of the Motivational Theory of Life-Span Development. Finally, because
the conceptual reach of their theory goes far beyond the current empirical base, they pointed out
areas that deserve further and more focused empirical inquiry.
文献类型: Review
作者关键词: life-span development; motivation; primary and secondary control; goal engagement
and disengagement
KeyWords
Plus:
SECONDARY
CONTROL STRATEGIES;
QUALITY-OF-LIFE;
ENGAGEMENT CONTROL STRATEGIES; IMPLEMENTAL MIND-SETS; PERCEIVED
CONTROL; OLDER-ADULTS; DEPRESSIVE SYMPTOMS; PERSONAL GOALS;
FUNCTIONAL DIFFICULTIES; INTERPERSONAL CONTROL
地址: [Heckhausen, Jutta] Univ Calif Irvine, Dept Psychol & Social Behav, Irvine, CA 92697
USA.
[Wrosch, Carsten] Concordia Univ, Dept Psychol, Montreal, PQ H3G 1M8, Canada.
[Wrosch, Carsten] Concordia Univ, Ctr Res Human Dev, Montreal, PQ H3G 1M8, Canada.
[Schulz, Richard] Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA 15260 USA.
[Schulz, Richard] Univ Pittsburgh, Ctr Social & Urban Res, Pittsburgh, PA 15260 USA.
通讯作者地址: Heckhausen, J (通讯作者),Univ Calif Irvine, Dept Psychol & Social Behav, 4316
Behav & Social Sci Gateway, Irvine, CA 92697 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 29
第 54 条，共 81 条
标题: Neighborhood Environment in Studies of Health of Older Adults A Systematic Review
作者: Yen, IH (Yen, Irene H.); Michael, YL (Michael, Yvonne L.); Perdue, L (Perdue, Leslie)
来源出版物 : AMERICAN JOURNAL OF PREVENTIVE MEDICINE 卷 : 37 期 : 5 页 :
455-463 DOI: 10.1016/j.amepre.2009.06.022 出版年: NOV 2009
Web of Science 核心合集中的 "被引频次": 147
被引频次合计: 148
引用的参考文献数: 112
摘要: Context: Epidemiologists and public health researchers are studying neighborhood's effect
on individual health. The health of older adults may be more influenced by their neighborhoods as
a result of decreased mobility. However, research on neighborhood's influence on older adults'
health, specifically, is limited.
Evidence acquisition: Recent studies on neighborhood and health for older adults were identified.
Studies were identified through searches of databases including PsycINFO, CINAHL, PubMed,
Academic Search Premier, Ageline, Social Science Citation Index, and Health Source. Criteria for
inclusion were as follows: human studies; English language; study sample included adults aged >=
55 years; health outcomes, including mental health, health behaviors, morbidity, and mortality;
neighborhood as the primary exposure variable of interest; empirical research; and studies that
included >= 10 neighborhoods. Air pollution studies were excluded. Five hundred thirty-eight
relevant articles were published during 19972007; a total of 33 of these articles met inclusion
criteria.
Evidence synthesis: The measures of objective and perceived aspects of neighborhood were
summarized. Neighborhood was primarily operationalized using census-defined boundaries.
Measures of neighborhood were principally derived from objective sources of data; eight studies
assessed perceived neighborhood alone or in combination with objective measures. Six categories
of neighborhood characteristics were socioeconomic composition, racial composition,
demographics, perceived resources and/or problems, physical environment, and social
environment. The studies are primarily cross-sectional and use administrative data to characterize
neighborhood.
Conclusions: These studies suggest that neighborhood environment is important for older adults'
health and functioning. (Am J Prev Med 2009;37(5):455-463) (C) 2009 American Journal of
Preventive Medicine
文献类型: Review
KeyWords Plus: CORONARY-HEART-DISEASE; QUALITY-OF-LIFE; SELF-RATED
HEALTH;
POPULATION-BASED
COHORT;
PHYSICAL-ACTIVITY;
SOCIOECONOMIC-STATUS; BUILT ENVIRONMENT; DEPRESSIVE SYMPTOMS;
UNITED-STATES; MULTILEVEL ANALYSIS
地址: [Yen, Irene H.] Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USA.
[Michael, Yvonne L.; Perdue, Leslie] Oregon Hlth & Sci Univ, Dept Publ Hlth & Prevent Med,
Portland, OR 97201 USA.
通讯作者地址: Yen, IH (通讯作者),Univ Calif San Francisco, Dept Med, 3333 Calif St,Suite
335, San Francisco, CA 94143 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 9
第 55 条，共 81 条
标题: What is self-rated health and why does it predict mortality? Towards a unified conceptual
model
作者: Jylha, M (Jylha, Marja)
来 源 出 版 物 : SOCIAL SCIENCE & MEDICINE 卷 : 69 期 : 3 页 : 307-316 DOI:
10.1016/j.socscimed.2009.05.013 出版年: AUG 2009
Web of Science 核心合集中的 "被引频次": 404
被引频次合计: 417
引用的参考文献数: 133
摘要: The association of self-rated health with mortality is well established but poorly understood.
This paper provides new insights into self-rated health that help integrate information from
different disciplines, both social and biological, into one unified conceptual framework. It
proposes, first, a model describing the health assessment process to show how self-rated health
can reflect the states of the human body and mind. Here, an analytic distinction is made between
the different types of information on which people base their health assessments and the
contextual frameworks in which this information is evaluated and summarized. The model helps
us understand why self-ratings of health may be modified by age or culture, but still be a valid
measure of health status. Second, based on the proposed model, the paper examines the
association of self-rated health with mortality. The key question is, what do people know and how
do they know what they know that makes self-rated health such an inclusive and universal
predictor of the most absolute biological event, death. The focus is on the social and biological
pathways that mediate information from the human organism to individual consciousness, thus
incorporating that information into self-ratings of health. A unique source of information is
provided by the bodily sensations that are directly available only to the individual him- or herself.
According to recent findings in human biology, these sensations may reflect important
physiological dysregulations, such as inflammatory processes. Third, the paper discusses the
advantages and limitations of self-rated health as a measure of health in research and clinical
practice. Future research should investigate both the logics that govern people's reasoning about
their health and the physiological processes that underlie bodily feelings and sensations. Self-rated
health ties at the cross-roads of culture and biology, therefore a collaborative effort between
different disciplines can only improve our understanding of this key measure of health status. (C)
2009 Elsevier Ltd. All rights reserved.
文献类型: Review
作 者 关 键 词 : Mortality; Cognition; Self-assessment; Interoception; Symptoms; Biology;
Self-rated health; Review
KeyWords Plus: QUALITY-OF-LIFE; ASSESSED HEALTH; OLDER-ADULTS; FOLLOW-UP;
REPORTED HEALTH; WHITE ADULTS; RISK-FACTORS; ELDERLY-MEN; ALL-CAUSE;
CARDIOVASCULAR MORTALITY
地址: Univ Tampere, Sch Publ Hlth, FIN-33014 Tampere, Finland.
通讯作者地址: Jylha, M (通讯作者),Univ Tampere, Sch Publ Hlth, FIN-33014 Tampere, Finland.
电子邮件地址: [email protected]
来源出版物页码计数: 10
第 56 条，共 81 条
标题: Exercise and Physical Activity for Older Adults
作者: Chodzko-Zajko, WJ (Chodzko-Zajko, Wojtek J.); Proctor, DN (Proctor, David N.); Singh,
MAF (Singh, Maria A. Fiatarone); Minson, CT (Minson, Christopher T.); Nigg, CR (Nigg,
Claudio R.); Salem, GJ (Salem, George J.); Skinner, JS (Skinner, James S.)
来源出版物: MEDICINE AND SCIENCE IN SPORTS AND EXERCISE 卷: 41 期: 7 页:
1510-1530 DOI: 10.1249/MSS.0b013e3181a0c95c 出版年: JUL 2009
Web of Science 核心合集中的 "被引频次": 634
被引频次合计: 662
引用的参考文献数: 271
摘要: The purpose of this Position Stand is to provide an overview Of issues critical to
understanding the importance of exercise and physical activity in older adult populations. The
Position Stand is divided into three sections: Section I briefly reviews the structural and functional
changes that characterize normal human aging, Section 2 considers the extent to which exercise
and physical activity can influence the aging process, and Section 3 summarizes the benefits of
both long-term exercise and physical activity and shorter-duration exercise programs on health
and functional capacity. Although no amount of physical activity can stop the biological aging
process, there is evidence that regular exercise can minimize the physiological effects of an
otherwise sedentary lifestyle and increase active life expectancy by limiting the development and
progression of chronic disease and disabling conditions. There is also emerging evidence for
significant psychological and cognitive benefits accruing from regular exercise participation by
older adults. Ideally, exercise prescription for older adults should include aerobic exercise, muscle
strengthening exercises, and flexibility exercises. The evidence reviewed in this Position Stand is
generally consistent with prior American College of Sports Medicine statements on the types and
amounts of physical activity recommended for older adults as well as the recently published 2008
Physical Activity Guidelines for Americans. All older adults should engage in regular physical
activity and avoid an inactive lifestyle.
文献类型: Review
KeyWords Plus: BONE-MINERAL DENSITY; RANDOMIZED CONTROLLED-TRIAL;
AMERICAN-HEART-ASSOCIATION;
QUALITY-OF-LIFE;
FORCE
PRODUCTION
CHARACTERISTICS; INTRAABDOMINAL ADIPOSE-TISSUE; ISOMETRIC MUSCLE
STRENGTH; MESSENGER-RNA EXPRESSION; ENDURANCE-TRAINED MEN; HUMAN
SKELETAL-MUSCLE
来源出版物页码计数: 21
第 57 条，共 81 条
标题: What is a meaningful change in physical performance? Findings from a clinical trial in
older adults (the LIFE-P study)
作者: Kwon, S (Kwon, S.); Perera, S (Perera, S.); Pahor, M (Pahor, M.); Katula, JA (Katula, J.
A.); King, AC (King, A. C.); Groessl, EJ (Groessl, E. J.); Studenski, SA (Studenski, S. A.)
来源出版物: JOURNAL OF NUTRITION HEALTH & AGING 卷: 13 期: 6 页: 538-544 DOI:
10.1007/s12603-009-0104-z 出版年: JUN 2009
Web of Science 核心合集中的 "被引频次": 103
被引频次合计: 107
引用的参考文献数: 26
摘要: Performance measures provide important information, but the meaning of change in these
measures is not well known. The purpose of this research is to 1) examine the effect of treatment
assignment on the relationship between self-report and performance; 2) to estimate the magnitude
of meaningful change in 400- meter walk time (400MWT), 4-meter gait speed (4MGS), and Short
Physical Performance Battery (SPPB) and 3) to evaluate the effect of direction of change on
estimates of magnitude.
This is a secondary analysis of data from the LIFE-P study, a single blinded randomized clinical
trial. Using change over one year, we applied distribution-based and anchor-based methods for
self-reported mobility to estimate minimally important and substantial change in 400MWT, 4MGS
and SPPB.
Four university-based clinical research sites.
Sedentary adults aged 70-89 whose SPPB scores were less than 10 and who were able to complete
a 400MW at baseline (n=424).
A structured exercise program versus health education.
400MWT, 4MGS, SPPB.
Relationships between self-report and performance measures were consistent between treatment
arms. Minimally significant change estimates were 400MWT: 20-30 seconds, 4MGS:
0.03-0.05m/s and SPPB: 0.3-0.8 points. Substantial changes were 400MWT: 50-60 seconds,
4MGS: 0.08m/s, SPPB: 0.4-1.5 points. Magnitudes of change for improvement and decline were
not significantly different.
The magnitude of clinically important change in physical performance measures is reasonably
consistent using several analytic techniques and appears to be achievable in clinical trials of
exercise. Due to limited power, the effect of direction of change on estimates of magnitude
remains uncertain.
文献类型: Article
作者关键词: Aging; physical performance; meaningful change
KeyWords Plus: QUALITY-OF-LIFE; LOWER-EXTREMITY FUNCTION; STYLE
INTERVENTIONS; MOBILITY LIMITATION; WALK TEST; HEALTH; INDEPENDENCE;
DISABILITY; EFFICACY; ASSOCIATION
地址: [Kwon, S.] Univ Florida, Coll Pharm, Gainesville, FL 32610 USA.
[Kwon, S.] Rehabil Outcomes Res Ctr NF SG VHA, Gainesville, FL USA.
[Kwon, S.; Pahor, M.] Univ Florida, Inst Aging, Gainesville, FL USA.
[Perera, S.; Studenski, S. A.] Univ Pittsburgh, Div Geriatr Med, Pittsburgh, PA USA.
[Perera, S.] Univ Pittsburgh, Dept Biostat, Pittsburgh, PA 15261 USA.
[Perera, S.; Studenski, S. A.] Univ Pittsburgh, Inst Aging, Pittsburgh, PA 15261 USA.
[Pahor, M.] Univ Florida, Coll Med, Dept Aging & Geriatr Res, Gainesville, FL USA.
[Katula, J. A.] Wake Forest Univ, Winston Salem, NC 27109 USA.
[Katula, J. A.] Wake Forest Univ, Inst Aging, Palo Alto, CA USA.
[King, A. C.] Stanford Univ, Sch Med, Palo Alto, CA 94304 USA.
[Groessl, E. J.] VA San Diego Hlth Care Syst, San Diego, CA USA.
[Groessl, E. J.] Univ Calif San Diego, San Diego, CA 92103 USA.
[Studenski, S. A.] Dept Vet Affairs Hosp, Ctr Geriatr Res Educ & Clin, Pittsburgh, PA USA.
通讯作者地址: Kwon, S (通讯作者),Univ Florida, Coll Pharm, Gainesville, FL 32610 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 7
第 58 条，共 81 条
标题: Evidence-Based Recommendations for the Assessment and Management of Sleep Disorders
in Older Persons
作者: Bloom, HG (Bloom, Harrison G.); Ahmed, I (Ahmed, Imran); Alessi, CA (Alessi, Cathy A.);
Ancoli-Israel, S (Ancoli-Israel, Sonia); Buysse, DJ (Buysse, Daniel J.); Kryger, MH (Kryger, Meir
H.); Phillips, BA (Phillips, Barbara A.); Thorpy, MJ (Thorpy, Michael J.); Vitiello, MV (Vitiello,
Michael V.); Zee, PC (Zee, Phyllis C.)
来源出版物: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 卷: 57 期: 5 页:
761-789 DOI: 10.1111/j.1532-5415.2009.02220.x 出版年: MAY 2009
Web of Science 核心合集中的 "被引频次": 114
被引频次合计: 120
引用的参考文献数: 293
摘要: Sleep-related disorders are most prevalent in the older adult population. A high prevalence
of medical and psychosocial comorbidities and the frequent use of multiple medications, rather
than aging per se, are major reasons for this. A major concern, often underappreciated and
underaddressed by clinicians, is the strong bidirectional relationship between sleep disorders and
serious medical problems in older adults. Hypertension, depression, cardiovascular disease, and
cerebrovascular disease are examples of diseases that are more likely to develop in individuals
with sleep disorders. Conversely, individuals with any of these diseases are at a higher risk of
developing sleep disorders. The goals of this article are to help guide clinicians in their general
understanding of sleep problems in older persons, examine specific sleep disorders that occur in
older persons, and suggest evidence- and expert-based recommendations for the assessment and
treatment of sleep disorders in older persons. No such recommendations are available to help
clinicians in their daily patient care practices. The four sections in the beginning of the article are
titled, Background and Significance, General Review of Sleep, Recommendations Development,
and General Approach to Detecting Sleep Disorders in an Ambulatory Setting. These are followed
by overviews of specific sleep disorders: Insomnia, Sleep Apnea, Restless Legs Syndrome,
Circadian Rhythm Sleep Disorders, Parasomnias, Hypersomnias, and Sleep Disorders in
Long-Term Care Settings. Evidence- and expert-based recommendations, developed by a group of
sleep and clinical experts, are presented after each sleep disorder.
文献类型: Review
KeyWords Plus: RESTLESS-LEGS-SYNDROME; NURSING-HOME RESIDENTS; POSITIVE
AIRWAY PRESSURE; EXCESSIVE DAYTIME SLEEPINESS; BRIGHT-LIGHT THERAPY;
QUALITY-OF-LIFE;
RANDOMIZED
CONTROLLED-TRIAL;
PERIODIC
LIMB
MOVEMENTS; COMMUNITY-DWELLING ADULTS; CHEYNE-STOKES RESPIRATION
地址: [Bloom, Harrison G.] Int Longev Ctr USA, New York, NY 10028 USA.
[Bloom, Harrison G.] Mt Sinai Sch Med, Brookdale Dept Geriatr & Adult Dev, New York, NY
USA.
[Ahmed, Imran; Vitiello, Michael V.] Albert Einstein Coll Med, New York, NY USA.
[Alessi, Cathy A.] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA.
[Alessi, Cathy A.] Vet Affairs Greater Los Angeles Healthcare Syst, Ctr Geriatr Res Educ & Clin,
Los Angeles, CA USA.
[Ancoli-Israel, Sonia] Univ Calif San Diego, Sch Med, San Diego, CA 92103 USA.
[Buysse, Daniel J.] Univ Pittsburgh, Sch Med, Neurosci Clin & Translat Ctr, Pittsburgh, PA USA.
[Kryger, Meir H.] Gaylord Hosp, Gaylord Sleep Ctr, Wallingford, CT USA.
[Kryger, Meir H.] Univ Connecticut, Sch Med, Dept Med, Farmington, CT USA.
[Phillips, Barbara A.] Natl Sleep Fdn, Washington, DC USA.
[Phillips, Barbara A.] Univ Kentucky, Coll Med, Lexington, KY USA.
[Thorpy, Michael J.] Montefiore Med Ctr, Ctr Sleep Wake Disorders, Bronx, NY 10467 USA.
[Vitiello, Michael V.] Univ Washington, Seattle, WA 98195 USA.
[Zee, Phyllis C.] Northwestern Univ, Dept Neurol, Chicago, IL 60611 USA.
通讯作者地址: Bloom, HG (通讯作者),Int Longev Ctr USA, 60 E 86th St, New York, NY 10028
USA.
电子邮件地址: [email protected]
来源出版物页码计数: 29
第 59 条，共 81 条
标题: The PHQ-8 as a measure of current depression in the general population
作者: Kroenke, K (Kroenke, Kurt); Strine, TW (Strine, Tara W.); Spitzer, RL (Spitzer, Robert L.);
Williams, JBW (Williams, Janet B. W.); Berry, JT (Berry, Joyce T.); Mokdad, AH (Mokdad, Ali
H.)
来源出版物: JOURNAL OF AFFECTIVE DISORDERS 卷: 114 期: 1-3 页: 163-173 DOI:
10.1016/j.jad.2008.06.026 出版年: APR 2009
Web of Science 核心合集中的 "被引频次": 333
被引频次合计: 335
引用的参考文献数: 62
摘要: Background: The eight-item Patient Health Questionnaire depression scale (PHQ-8) is
established as a valid diagnostic and severity measure for depressive disorders in large clinical
studies. Our objectives were to assess the PHQ-8 as a depression measure in a large,
epidemiological population-based study, and to determine the comparability of depression as
defined by the PHQ-8 diagnostic algorithm vs. a PHQ-8 cutpoint >= 10,
Methods: Random-digit-dialed telephone survey of 198,678 participants in the 2006 Behavioral
Risk Factor Surveillance Survey (BRFSS), a population-based survey in the United States. Current
depression as defined by either the DSM-IV based diagnostic algorithm (i.e., major depressive or
other depressive disorder) of the PHQ-8 or a PHQ-8 score >= 10; respondent sociodemographic
characteristics; number of days of impairment in the past 30 days in multiple domains of
health-related quality of life (HRQoL).
Results: The prevalence of current depression was similar whether defined by the diagnostic
algorithm or a PHQ-8 score; ! 10 (9.1% vs. 8.6%). Depressed patients had substantially more days
of impairment across multiple domains of HRQoL, and the impairment was nearly identical in
depressed groups defined by either method. Of the 17,040 respondents with a PHQ-8 score >= 10,
major depressive disorder was present in 49.7%, other depressive disorder in 23.9%, depressed
mood or anhedonia in another 22.8%, and no evidence of depressive disorder or depressive
symptoms in only 3.5%.
Limitations: The PHQ-9 diagnostic algorithm rather than an independent structured psychiatric
interview was used as the criterion standard.
Conclusions: The PHQ-X is a useful depression measure far population-based studies, and either
its diagnostic algorithm or a cutpoint >= 10 can be used for defining current depression. (c) 2009
Elsevier B.V. All rights reserved.
文献类型: Article
作者关键词: Depression; Psychometrics; Prevalence; Epidemiology; Quality of life; Patient
Health Questionnaire
KeyWords
Plus:
PATIENT
HEALTH
QUESTIONNAIRE;
QUALITY-OF-LIFE;
PRIMARY-CARE
PATIENTS;
NATIONAL-COMORBIDITY-SURVEY;
TRAUMATIC
BRAIN-INJURY; PSYCHIATRIC COMORBIDITY; COLLABORATIVE CARE; MAJOR
DEPRESSION; OLDER-ADULTS; DISORDERS
地址: [Kroenke, Kurt] Regenstrief Inst Hlth Care, Indianapolis, IN 46202 USA.
[Kroenke, Kurt] Indiana Univ, Sch Med, Dept Med, Indianapolis, IN USA.
[Strine, Tara W.; Mokdad, Ali H.] Ctr Dis Control & Prevent, Atlanta, GA USA.
[Spitzer, Robert L.; Williams, Janet B. W.] Columbia Univ, Dept Psychiat, New York, NY USA.
[Spitzer, Robert L.; Williams, Janet B. W.] New York State Psychiat Inst & Hosp, New York, NY
10032 USA.
通讯作者地址: Kroenke, K (通讯作者),Regenstrief Inst Hlth Care, RG-6 1050 Wishard Blvd,
Indianapolis, IN 46202 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 11
第 60 条，共 81 条
标题: A Cognitive Training Program Based on Principles of Brain Plasticity: Results from the
Improvement in Memory with Plasticity-based Adaptive Cognitive Training (IMPACT) Study
作者: Smith, GE (Smith, Glenn E.); Housen, P (Housen, Patricia); Yaffe, K (Yaffe, Kristine); Ruff,
R (Ruff, Ronald); Kennison, RF (Kennison, Robert F.); Mahncke, HW (Mahncke, Henry W.);
Zelinski, EM (Zelinski, Elizabeth M.)
来源出版物: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 卷: 57 期: 4 页:
594-603 DOI: 10.1111/j.1532-5415.2008.02167.x 出版年: APR 2009
Web of Science 核心合集中的 "被引频次": 213
被引频次合计: 216
引用的参考文献数: 50
摘要: To investigate the efficacy of a novel brain plasticity-based computerized cognitive training
program in older adults and to evaluate the effect on untrained measures of memory and attention
and participant-reported outcomes.
Multisite randomized controlled double-blind trial with two treatment groups.
Communities in northern and southern California and Minnesota.
Community-dwelling adults aged 65 and older (N=487) without a diagnosis of clinically
significant cognitive impairment.
Participants were randomized to receive a broadly-available brain plasticity-based computerized
cognitive training program (intervention) or a novelty- and intensity-matched general cognitive
stimulation program modeling treatment as usual (active control). Duration of training was 1 hour
per day, 5 days per week, for 8 weeks, for a total of 40 hours.
The primary outcome was a composite score calculated from six subtests of the Repeatable
Battery for the Assessment of Neuropsychological Status that use the auditory modality (RBANS
Auditory Memory/Attention). Secondary measures were derived from performance on the
experimental program, standardized neuropsychological assessments of memory and attention,
and participant-reported outcomes.
RBANS Auditory Memory/Attention improvement was significantly greater (P=.02) in the
experimental group (3.9 points, 95% confidence interval (CI)=2.7-5.1) than in the control group
(1.8 points, 95% CI=0.6-3.0). Multiple secondary measures of memory and attention showed
significantly greater improvements in the experimental group (word list total score, word list
delayed recall, digits backwards, letter-number sequencing; P <.05), as did the participant-reported
outcome measure (P=.001). No advantage for the experimental group was seen in narrative
memory.
The experimental program improved generalized measures of memory and attention more than an
active control program.
文献类型: Article; Proceedings Paper
作者关键词: clinical trial; cognitive decline; computerized cognitive training; participant-reported
outcomes; brain plasticity
KeyWords Plus: QUALITY-OF-LIFE; HEALTHY OLDER-ADULTS; CLINICAL-TRIALS;
SELF-EFFICACY; PERFORMANCE; SPEED; INTERVENTION; DEMENTIA; AGE;
IMPAIRMENT
地址: [Smith, Glenn E.] Mayo Clin, Dept Psychiat & Psychol, Rochester, MN 55905 USA.
[Housen, Patricia; Zelinski, Elizabeth M.] Univ So Calif, Leonard Davis Sch Gerontol, Los
Angeles, CA USA.
[Yaffe, Kristine; Ruff, Ronald; Kennison, Robert F.] Univ Calif San Francisco, Dept Psychiat, San
Francisco, CA 94143 USA.
[Yaffe, Kristine] Univ Calif San Francisco, Dept Neurol, San Francisco, CA 94143 USA.
[Yaffe, Kristine] Univ Calif San Francisco, Dept Epidemiol, San Francisco, CA 94143 USA.
[Ruff, Ronald] Stanford Univ, Div Phys Med & Rehabil, Stanford, CA 94305 USA.
[Kennison, Robert F.] Calif State Univ Los Angeles, Dept Psychol, Los Angeles, CA 90032 USA.
[Mahncke, Henry W.] Posit Sci Corp, San Francisco, CA USA.
通讯作者地址: Smith, GE (通讯作者),Mayo Clin, Dept Psychiat & Psychol, 200 First St SW,
Rochester, MN 55905 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 10
第 61 条，共 81 条
标题: Exercising Your Brain: A Review of Human Brain Plasticity and Training-Induced Learning
作者: Green, CS (Green, C. S.); Bavelier, D (Bavelier, D.)
来源出版物: PSYCHOLOGY AND AGING 卷: 23 期: 4 页: 692-701 DOI: 10.1037/a0014345
出版年: DEC 2008
Web of Science 核心合集中的 "被引频次": 163
被引频次合计: 165
引用的参考文献数: 130
摘要: Human beings have an amazing capacity to learn new skills and adapt to new environments.
However. several obstacles remain to be overcome in designing paradigms to broadly improve
quality of life. Arguably, the most notable impediment to this goal is that learning tends to be quite
specific 10 the trained regimen and does not transfer to even qualitatively similar tasks. This
severely limits the potential benefits of learning to daily life. This review discusses training
regimens that lead to the acquisition of new knowledge and strategies that can be Used flexibly
across a range of tasks and contexts. Possible characteristics of training regimens are proposed
that may be responsible for augmented learning. including the manner in which task difficulty is
progressed, the motivational state of the learner. and the type of feedback the training provides.
When maximally implemented in rehabilitative paradigms, these characteristics may greatly
increase the efficacy of training.
文献类型: Review
KeyWords Plus: VIDEO-GAME EXPERIENCE; MULTIPLE-OBJECT TRACKING; ADULT
BARN OWLS; VISUAL-SEARCH; OLDER-ADULTS; CORTICAL PLASTICITY;
RECONCEPTUALIZING AROUSAL; MOTION DISCRIMINATION; COGNITIVE
PERFORMANCE; SKILL ACQUISITION
地址: [Green, C. S.] Univ Minnesota, Dept Psychol, Minneapolis, MN 55455 USA.
[Bavelier, D.] Univ Rochester, Dept Brain & Cognit Sci, Rochester, NY 14627 USA.
通讯作者地址: Green, CS (通讯作者),Univ Minnesota, Dept Psychol, 75 E River Rd N218 Elliot
Hall, Minneapolis, MN 55455 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 10
第 62 条，共 81 条
标题: Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease
- A randomized trial
作者: Lautenschlager, NT (Lautenschlager, Nicola T.); Cox, KL (Cox, Kay L.); Flicker, L (Flicker,
Leon); Foster, JK (Foster, Jonathan K.); van Bockxmeer, FM (van Bockxmeer, Frank M.); Xiao,
JG (Xiao, Jianguo); Greenop, KR (Greenop, Kathryn R.); Almeida, OP (Almeida, Osvaldo P.)
来源出版物: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 卷: 300 期:
9 页: 1027-1037 DOI: 10.1001/jama.300.9.1027 出版年: SEP 3 2008
Web of Science 核心合集中的 "被引频次": 506
被引频次合计: 516
引用的参考文献数: 51
摘要: Context Many observational studies have shown that physical activity reduces the risk of
cognitive decline; however, evidence from randomized trials is lacking.
Objective To determine whether physical activity reduces the rate of cognitive decline among
older adults at risk.
Design and Setting Randomized controlled trial of a 24- week physical activity intervention
conducted between 2004 and 2007 in metropolitan Perth, Western Australia. Assessors of
cognitive function were blinded to group membership.
Participants We recruited volunteers who reported memory problems but did not meet criteria for
dementia. Three hundred eleven individuals aged 50 years or older were screened for eligibility,
89 were not eligible, and 52 refused to participate. A total of 170 participants were randomized
and 138 participants completed the 18- month assessment.
Intervention Participants were randomly allocated to an education and usual care group or to a 24week home- based program of physical activity.
Main Outcome Measure Change in Alzheimer Disease Assessment Scale Cognitive Subscale
( ADAS- Cog) scores ( possible range, 0- 70) over 18 months.
Results In an intent- to- treat analysis, participants in the intervention group improved 0.26 points
( 95% confidence interval, - 0.89 to 0.54) and those in the usual care group deteriorated 1.04
points ( 95% confidence interval, 0.32 to 1.82) on the ADAS- Cog at the end of the intervention.
The absolute difference of the outcome measure between the intervention and control groups was 1.3 points ( 95% confidence interval,- 2.38 to - 0.22) at the end of the intervention. At 18 months,
participants in the intervention group improved 0.73 points( 95% confidence interval, - 1.27 to
0.03) on the ADAS- Cog, and those in the usual care group improved 0.04 points ( 95%
confidence interval, - 0.46 to 0.88). Word list delayed recall and Clinical Dementia Rating sum of
boxes improved modestly as well, whereas word list total immediate recall, digit symbol coding,
verbal fluency, Beck depression score, and Medical Outcomes 36- Item Short- Form physical and
mental component summaries did not change significantly.
Conclusions In this study of adults with subjective memory impairment, a 6- month program of
physical activity provided a modest improvement in cognition over an 18-month follow- up
period.
Trial Registration anzctr.org.au Identifier: ACTRN12605000136606.
文献类型: Article
KeyWords
Plus:
QUALITY-OF-LIFE;
DOUBLE-BLIND;
CLINICAL-TRIALS;
PUBLIC-HEALTH; DENTATE GYRUS; EXERCISE; IMPAIRMENT; DEMENTIA;
PREVENTION; INTERVENTIONS
地址: [Lautenschlager, Nicola T.; Almeida, Osvaldo P.] Univ Western Australia, Sch Psychiat &
Clin Neurosci, Perth, WA 6009, Australia.
[Cox, Kay L.; Flicker, Leon] Univ Western Australia, Sch Med & Pharmacol, Perth, WA 6009,
Australia.
[van Bockxmeer, Frank M.] Univ Western Australia, Sch Pathol & Lab Med, Perth, WA 6009,
Australia.
[Foster, Jonathan K.] Edith Cowan Univ, Sch Exercise Biomed & Hlth Sci, Perth, WA, Australia.
[Foster, Jonathan K.] Hollywood Private Hosp, Neurosci Unit, Perth, WA, Australia.
[Xiao, Jianguo] Hollywood Private Hosp, Epidemiol Branch, Perth, WA, Australia.
[Foster, Jonathan K.] Hollywood Private Hosp, Dept Hlth Western Australia, Sir James McCusker
Alzheimers Dis Res Unit, Perth, WA, Australia.
[Lautenschlager, Nicola T.; Flicker, Leon; van Bockxmeer, Frank M.; Almeida, Osvaldo P.] Royal
Perth Hosp, Perth, WA, Australia.
[Lautenschlager, Nicola T.] Univ Melbourne, Acad Unit Psychiat Old Age, Dept Psychiat,
Melbourne, Vic, Australia.
通讯作者地址: Lautenschlager, NT (通讯作者),Univ Melbourne, Acad Unit Psychiat Old Age, St
Vincents Aged Psychiat Serv, Normanby Unit,St Vincents Hosp, St Georges Campus,283 Cotham
Rd, Kew, Vic 3101, Australia.
电子邮件地址: [email protected]
来源出版物页码计数: 11
第 63 条，共 81 条
标题: Prevalence of hearing loss and differences by demographic characteristics among US adults
- Data from the National Health and Nutrition Examination Survey, 1999-2004
作者: Agrawal, Y (Agrawal, Yuri); Platz, EA (Platz, Elizabeth A.); Niparko, JK (Niparko, John K.)
来源出版物: ARCHIVES OF INTERNAL MEDICINE 卷: 168 期: 14 页: 1522-1530 DOI:
10.1001/archinte.168.14.1522 出版年: JUL 28 2008
Web of Science 核心合集中的 "被引频次": 234
被引频次合计: 242
引用的参考文献数: 43
摘要: Background: Hearing loss affects health and quality of life. The prevalence of hearing loss
may be growing because of an aging population and increasing noise exposure. However, accurate
national estimates of hearing loss prevalence based on recent objective criteria are lacking.
Methods: We determined hearing loss prevalence among US adults and evaluated differences by
demographic characteristics and known risk factors for hearing loss (smoking, noise exposure, and
cardiovascular risks). A national cross-sectional survey with audiometric testing was performed.
Participants were 5742 US adults aged 20 to 69 years who participated in the audiometric
component of the National Health and Nutrition Examination Survey 1999-2004. The main
outcome measure was 25-dB or higher hearing loss at speech frequencies (0.5, 1, 2, and 4 kHz)
and at high frequencies (3, 4, and 6 kHz).
Results: In 2003-2004, 16.1% of US adults (29 million Americans) had speech-frequency hearing
loss. In the youngest age group (20-29 years), 8.5% exhibited hearing loss, and the prevalence
seems to be growing among this age group. Odds of hearing loss were 5.5-fold higher in men vs
women and 70% lower in black subjects vs white subjects. Increases in hearing loss prevalence
occurred earlier among participants with smoking, noise exposure, and cardiovascular risks.
Conclusions: Hearing loss is more prevalent among US adults than previously reported. The
prevalence of US hearing loss differs across racial/ethnic groups, and our data demonstrate
associations with risk factors identified in prior smaller-cohort studies'. Our findings also suggest
that hearing loss prevention (through modifiable risk factor reduction) and screening should begin
in young adulthood.
文献类型: Article
KeyWords Plus: OLDER-ADULTS; COGNITIVE DYSFUNCTION; NOISE EXPOSURE;
GREAT-BRITAIN;
PRIMARY-CARE;
RISK-FACTORS;
IMPAIRMENT;
AGE;
EPIDEMIOLOGY; COMMUNICATION
地址: [Agrawal, Yuri; Niparko, John K.] Johns Hopkins Univ Hosp, Dept Otolaryngol Head &
Neck Surg, Baltimore, MD 21287 USA.
[Platz, Elizabeth A.] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD
USA.
通讯作者地址: Agrawal, Y (通讯作者),Johns Hopkins Univ Hosp, Dept Otolaryngol Head &
Neck Surg, 601 N Caroline St, Baltimore, MD 21287 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 9
第 64 条，共 81 条
标题: Test-retest reliability and minimal detectable change on balance and ambulation tests, the
36-Item Short-Form Health Survey, and the unified Parkinson disease rating scale in people with
parkinsonism
作者: Steffen, T (Steffen, Teresa); Seney, M (Seney, Megan)
来源出版物: PHYSICAL THERAPY 卷: 88 期: 6 页: 733-746 DOI: 10.2522/ptj.20070214 出
版年: JUN 2008
Web of Science 核心合集中的 "被引频次": 197
被引频次合计: 200
引用的参考文献数: 93
摘要: Background and Purpose. Distinguishing between a clinically significant change and change
due to measurement error can be difficult. The purpose of this study was to determine test-retest
reliability and minimal detectable change for the Berg Balance Scale (BBS), forward and
backward functional reach, the Romberg Test and the Sharpened Romberg Test (SRT) with eyes
open and closed, the Activities-specific Balance Confidence (ABC) Scale, the Six-Minute Walk
Test (6MWT), comfortable and fast gait speed, the Timed "Up & Go" Test (TUG), the Medical
Outcomes Study 36-Item Short-Form Health Survey (SF-36), and the Unified Parkinson Disease
Rating Scale (UPDRS) in people with parkinsonism.
Subjects. Thirty-seven community-dwelling adults with parkinsonism (mean age=71 years)
participated. The Hoehn and Yahr Scale median score of 2 was on the lower end of the scale;
however, the scores ranged from I to 4.
Methods. Subjects were tested twice by the same raters, with I week between tests. Test-retest
reliability was calculated using intraclass correlation coefficients (ICCs). Minimal detectable
change was calculated using a 95% confidence interval (MDC95).
Results. The ICCs for test-retest reliability were above .90 for the BBS, ABC Scale, SRT with
eyes closed, 6MWT, and comfortable and fast gait speeds. The MDC95 values for those functional
tests were: BBS=5/56, ABC Scale=13%, SRT with eyes closed=19 seconds, 6MWT=82 m,
comfortable gait speed=0.18 m/s, and fast gait speed=0.25 m/s. The ICCs for test-retest reliability
of SF-36 scores were above .80, with the exception of the social functioning subscale. The
MDC95 values for the SF-36 ranged between 19% and 45%. The MDC95 values for the UPDRS
Activities of Daily Living section, Motor Examination section, and total scores were 4/52, 11/108,
and 13/176, respectively.
Discussion and Conclusion. Minimal detectable change values are useful to therapists in
rehabilitation and wellness programs in determining whether change during or after intervention is
clinically significant. High test-retest reliability of scores for the BBS, ABC Scale, SRT with eyes
closed, 6MWT, and gait speed make them trustworthy functional assessments in people with
parkinsonism. The SF-36 and UPDRS provide quality-of-life and disease severity rating values in
the ongoing assessment of people with parkinsonism.
文献类型: Article; Proceedings Paper
KeyWords Plus: 6-MINUTE WALK TEST; QUALITY-OF-LIFE; OBSTRUCTIVE
PULMONARY-DISEASE; PHYSICAL PERFORMANCE-MEASURES; PSYCHOMETRIC
PROPERTIES; FUNCTIONAL REACH; STROKE PATIENTS; HIP FRACTURE;
OLDER-ADULTS; GAIT PERFORMANCE
地址: [Steffen, Teresa; Seney, Megan] Concorida Univ Wisconsin, Program Phys Therapy,
Cedarburg, WI 53102 USA.
通讯作者地址: Steffen, T (通讯作者),Concorida Univ Wisconsin, Program Phys Therapy, N102
W7525 St James Ct, Cedarburg, WI 53102 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 14
第 65 条，共 81 条
标题: The associations between life satisfaction and health-related quality of life, chronic illness,
and health behaviors among US community-dwelling adults
作者: Strine, TW (Strine, Tara W.); Chapman, DP (Chapman, Daniel P.); Balluz, LS (Balluz, Lina
S.); Moriarty, DG (Moriarty, David G.); Mokdad, AH (Mokdad, Ali H.)
来 源 出 版 物 : JOURNAL OF COMMUNITY HEALTH 卷 : 33 期 : 1 页 : 40-50 DOI:
10.1007/s10900-007-9066-4 出版年: FEB 2008
Web of Science 核心合集中的 "被引频次": 93
被引频次合计: 96
引用的参考文献数: 65
摘要: The primary purpose of this article was to examine the associations between life satisfaction
level and health-related quality of life (HRQOL), chronic illness, and adverse health behaviors
among adults in the U. S. and its territories. Data were obtained from the 2005 Behavioral Risk
Factor Surveillance System, an ongoing, state-based, random-digit telephone survey of the
noninstitutionalized U. S. population aged 18 years. An estimated 5.6% of U. S. adults (about 12
million) reported that they were dissatisfied/very dissatisfied with their lives. As the level of life
satisfaction decreased, the prevalence of fair/poor general health, disability, and infrequent social
support increased as did the mean number of days in the past 30 days of physical distress, mental
distress, activity limitation, depressive symptoms, anxiety symptoms, sleep insufficiency, and
pain. The prevalence of smoking, obesity, physical inactivity, and heavy drinking also increased
with decreasing level of life satisfaction. Moreover, adults with chronic illnesses were
significantly more likely than those without to report life dissatisfaction. Notably, all of these
associations remained significant after adjusting for sociodemographic characteristics. Our
findings showed that HRQOL and health risk behaviors varied with level of life satisfaction. As
life satisfaction appears to encompass many individual life domains, it may be an important
concept for public health research.
文献类型: Article
作者关键词: life satisfaction; health behaviors; quality of life; chronic illness; surveillance
KeyWords
Plus:
SPINAL-CORD-INJURY;
18-TO
64-YEAR-OLD
SWEDES;
PHYSICAL-ACTIVITY; OLDER-ADULTS; COLLEGE-STUDENTS; SELF-ESTEEM;
DEPRESSION; PERSONALITY; PREDICTORS; ANXIETY
地址: [Strine, Tara W.; Chapman, Daniel P.; Balluz, Lina S.; Moriarty, David G.; Mokdad, Ali H.]
Ctr Dis Control & Prevent, Div Adult & Community Hlth, Atlanta, GA 30341 USA.
通讯作者地址: Strine, TW (通讯作者),Ctr Dis Control & Prevent, Div Adult & Community Hlth,
4770 Buford Highway NE,Mailstop K-66, Atlanta, GA 30341 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 11
第 66 条，共 81 条
标题: Multifactorial assessment and targeted intervention for preventing falls and injuries among
older people in community and emergency care settings: systematic review and meta-analysis
作者: Gates, S (Gates, S.); Fisher, JD (Fisher, J. D.); Cooke, MW (Cooke, M. W.); Carter, YH
(Carter, Y. H.); Lamb, SE (Lamb, S. E.)
来 源 出 版 物 : BRITISH MEDICAL JOURNAL 卷 : 336 期 : 7636 页 : 130-133 DOI:
10.1136/bmj.39412.525243.BE 出版年: JAN 19 2008
Web of Science 核心合集中的 "被引频次": 205
被引频次合计: 212
引用的参考文献数: 16
摘要: Objective To evaluate the effectiveness of multifactorial assessment and intervention
programmes to prevent falls and injuries among older adults recruited to trials in primary care,
community, or emergency care settings.
Design Systematic review of randomised and quasi-randomised controlled trials, and
meta-analysis
Data sources Six databases (Medline, Embase, CENTRAL, CINAHL, PsycINFO, Social Science
Citation Index) to 22 March 2007, reference lists of included studies, and previous reviews.
Review methods Eligible studies were randomised or quasi-randomised trials that evaluated
interventions to prevent falls that were based in emergency departments, primary care, or the
community, that assessed multiple risk factors for falling and provided or arranged for treatments
to address these risk factors.
Data extraction Outcomes were number of falters, fall related injuries, fall rate, death, admission
to hospital, contacts with health services, move to institutional care, physical activity, and quality
of life. Methodological quality assessment included allocation concealment, blinding, tosses and
exclusions, intention to treat analysis, and reliability of outcome measurement.
Results 19 studies, of variable methodological quality, were included. The combined risk ratio for
the number of falters during follow-up among 18 trials was 0.91 (95% confidence interval 0.82 to
1.02) and for fall. related injuries (eight trials) was 0.90 (0.68 to 1.20). No differences were found
in admissions to hospital, emergency department attendance, death, or move to institutional care.
Subgroup analyses found no evidence of different effects between interventions in different
locations, populations selected for high risk of falls or unselected, and multidisciplinary teams
including a doctor, but interventions that actively provide treatments may be more effective than
those that provide only knowledge and referral.
Conclusions Evidence that multifactorial fall prevention programmes in primary care community
or emergency care settings are effective in reducing the number of falters or fall related injuries is
limited. Data were insufficient to assess fall and injury rates.
文献类型: Review
KeyWords Plus: CLINICAL-TRIALS
地址: [Gates, S.; Fisher, J. D.; Cooke, M. W.; Carter, Y. H.; Lamb, S. E.] Univ Warwick, Warwick
Med Sch, Warwick Clin Trials Unit, Coventry CV4 7AL, W Midlands, England.
[Lamb, S. E.] Univ Oxford, Kadoorie Crit Care Res Ctr, Oxford OX1 2JD, England.
通讯作者地址: Gates, S (通讯作者),Univ Warwick, Warwick Med Sch, Warwick Clin Trials
Unit, Coventry CV4 7AL, W Midlands, England.
电子邮件地址: [email protected]
来源出版物页码计数: 6
第 67 条，共 81 条
标题: US norms for six generic health-related quality-of-life indexes from the national health
measurement study
作者: Fryback, DG (Fryback, Dennis G.); Dunham, NC (Dunham, Nancy Cross); Palta, M (Palta,
Mari); Hanmer, J (Hanmer, Janel); Buechner, J (Buechner, Jennifer); Cherepanov, D (Cherepanov,
Dasha); Herrington, SA (Herrington, Shani A.); Hays, RD (Hays, Ron D.); Kaplan, RM (Kaplan,
Robert M.); Ganiats, TG (Ganiats, Theodore G.); Feeny, D (Feeny, David); Kind, P (Kind, Paul)
来源出版物: MEDICAL CARE 卷: 45 期: 12 页: 1162-1170 出版年: DEC 2007
Web of Science 核心合集中的 "被引频次": 169
被引频次合计: 171
引用的参考文献数: 31
摘 要 : Background: A number of indexes measuring self-reported generic health-related
quality-of-life (HRQoL) using preference-weighted scoring are used widely in population surveys
and clinical studies in the United States.
Objective: To obtain age-by-gender norms for older adults on 6 generic HRQoL indexes in a
cross-sectional US population survey and compare age-related trends in HRQoL.
Methods: The EuroQol EQ-5D, Health Utilities Index Mark 2, Health Utilities Index Mark 3,
SF-36v2 (TM) (used to compute SF-6D), Quality of Well-being Scale self-administered form, and
Health and Activities Limitations index were administered via telephone interview to each
respondent in a national survey sample of 3844 noninstitutionalized adults age 35-89. Persons age
65-89 and telephone exchanges with high percentages of African Americans were oversampled.
Age-by-gender means were computed using sampling and poststratification weights to adjust
results to the US adult population.
Results: The 6 indexes exhibit similar patterns of age-related HRQoL by gender; however, means
differ significantly across indexes. Females report slightly lower HRQoL than do males across all
age groups. HRQoL seems somewhat higher for persons age 65-74 compared with people in the
next younger age decade, as measured by all indexes.
Conclusions: Six HRQoL measures show similar but not identical trends in population norms for
older US adults. Results reported here provide reference values for 6 self-reported HRQoL
indexes.
文献类型: Article; Proceedings Paper
作者关键词: health-related quality-of-life; health status; EQ-5D; SF-6D; QWB-SA; SF-6D;
Health Utilities Index; HUI2; HUI3; SF-36; population survey; adults; aging; patient-reported
outcomes; health outcomes measures; comparative studies
KeyWords Plus: PREFERENCE-BASED MEASURE; UNITED-STATES; UTILITIES INDEX;
EQ-5D; POPULATION; SCORES; SF-36; QUESTIONNAIRE; SELECTION; CATALOG
地址: Univ Wisconsin, Dept Populat Hlth Sci, Madison, WI 53726 USA.
Univ Wisconsin, Dept Ind & Syst Engn, Madison, WI USA.
Univ Calif Los Angeles, Dept Med, Los Angeles, CA 90024 USA.
Univ Calif Los Angeles, Dept Hlth Serv, Los Angeles, CA USA.
RAND Corp, Santa Monica, CA USA.
Univ Calif San Diego, Dept Family & Prevent Med, San Diego, CA 92103 USA.
Hlth Util Inc, Dundas, ON, Canada.
Kaiser Permanente NW, Ctr Hlth Res, Portland, OR USA.
Univ York, Ctr Hlth Econ, York YO10 5DD, N Yorkshire, England.
通讯作者地址: Fryback, DG (通讯作者),Univ Wisconsin, Dept Populat Hlth Sci, 610 Walnut St,
Madison, WI 53726 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 9
第 68 条，共 81 条
标题: A population-based study of the incidence and complication rates of herpes zoster before
zoster vaccine introduction
作者: Yawn, BP (Yawn, Barbara P.); Saddier, P (Saddier, Patricia); Wollan, PC (Wollan, Peter C.);
Sauver, JLS (Sauver, Jennifer L. St.); Kurland, MJ (Kurland, Marge J.); Sy, LS (Sy, Lina S.)
来源出版物: MAYO CLINIC PROCEEDINGS 卷: 82 期: 11 页: 1341-1349 出版年: NOV
2007
Web of Science 核心合集中的 "被引频次": 239
被引频次合计: 244
引用的参考文献数: 50
摘要: OBJECTIVE: To establish accurate, up-to-date, baseline epidemiological data for herpes
zoster (HZ) before the introduction of the recently licensed HZ vaccine.
METHODS: Using data from January 1, 1996, to October 15, 2005, we conducted a
population-based study of adult residents (222 years) of Olmsted County, MN, to determine (by
medical record review) the incidence of HZ and the rate of HZ-related complications. Incidence
rates were determined by age and sex and adjusted to the US population.
RESULTS: A total of 1669 adult residents with a confirmed diagnosis of HZ were identified
between January 1, 1996, and December 31, 2001. Most (92%) of these patients were
immunocompetent and 60% were women. When adjusted to the US adult population, the
incidence of HZ was 3.6 per 1000 person-years (95% confidence interval, 3.4-3.7), with a
temporal increase from 3.2 to 4.1 per 1000 person-years from 1996 to 2001. The incidence of HZ
and the rate of HZ-associated complications increased with age, with 68% of cases occurring in
those aged 50 years and older. Postherpetic neuralgia occurred in 18% of adult patients with HZ
and in 33% of those aged 79 years and older. Overall, 10% of all patients with HZ experienced 1
or more nonpain complications.
CONCLUSIONS: Our population-based data suggest that HZ primarily affects immunocompetent
adults older than 50 years; 1 in 4 experiences some type of HZ-related complication.
文献类型: Article
KeyWords
Plus:
QUALITY-OF-LIFE;
POSTHERPETIC
NEURALGIA;
VARICELLA-VACCINATION;
OLDER-ADULTS;
COST-EFFECTIVENESS;
CONTROLLED-TRIAL; EPIDEMIOLOGY; PAIN; IMPACT; VIRUS
地址: Olmsted Med Ctr, Res Dept, Rochester, MN USA.
Merck Res Labs, Dept Epidemiol, N Wales, PA USA.
Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA.
通讯作者地址: Yawn, BP (通讯作者),Olmsted Med Ctr, Res Dept, 210 9th St SE, Rochester, MN
USA.
电子邮件地址: [email protected]
来源出版物页码计数: 9
第 69 条，共 81 条
标题: Depression, chronic diseases, and decrements in health: results from the World Health
Surveys
作者: Moussavi, S (Moussavi, Saba); Chatterji, S (Chatterji, Somnath); Verdes, E (Verdes,
Emese); Tandon, A (Tandon, Ajay); Patel, V (Patel, Vikram); Ustun, B (Ustun, Bedirhan)
来源出版物: LANCET 卷: 370 期: 9590 页: 851-858 DOI: 10.1016/S0140-6736(07)61415-9
出版年: SEP 8 2007
Web of Science 核心合集中的 "被引频次": 988
被引频次合计: 1015
引用的参考文献数: 49
摘要: Background Depression is an important public-health problem, and one of the leading
causes of disease burden worldwide. Depression is often comorbid with other chronic diseases and
can worsen their associated health outcomes. Few studies have explored the effect of depression,
alone or as a comorbidity, on overall health status.
Methods The WHO World Health Survey (WHS) studied adults aged 18 years and older to obtain
data for health, health-related outcomes, and their determinants. Prevalence of depression in
respondents based on ICD-10 criteria was estimated. Prevalence values for four chronic physical
diseases-angina, arthritis, asthma, and diabetes-were also estimated using algorithms derived via a
Diagnostic Item Probability Study. Mean health scores were constructed using factor analysis and
compared across different disease states and demographic variables. The relation of these disease
states to mean health scores was determined through regression modelling.
Findings Observations were available for 245 404 participants from 60 countries in all regions of
the world. Overall, 1-year prevalence for ICD-10 depressive episode alone was 3.2% (95% CI
3.0-3.5); for angina 4.5% (4.3-4.8); for arthritis 4.1% (3.8-4.3); for asthma 3.3% (2.9-3.6); and for
diabetes 2.0% (1.8-2.2). An average of between 9.3% and 23.0% of participants with one or more
chronic physical disease had comorbid depression. This result was significantly higher than the
likelihood of having depression in the absence of a chronic physical disease (p<0.0001). After
adjustment for socioeconomic factors and health conditions, depression had the largest effect on
worsening mean health scores compared with the other chronic conditions. Consistently across
countries and different demographic characteristics, respondents with depression comorbid with
one or more chronic diseases had the worst health scores of all the disease states.
Interpretation Depression produces the greatest decrement in health compared with the chronic
diseases angina, arthritis, asthma, and diabetes. The comorbid state of depression incrementally
worsens health compared with depression alone, with any of the chronic diseases alone, and with
any combination of chronic diseases without depression. These results indicate the urgency of
addressing depression as a public-health priority to reduce disease burden and disability, and to
improve the overall health of populations.
文献类型: Article
KeyWords Plus: QUALITY-OF-LIFE; PRIMARY-CARE PATIENTS; MAJOR DEPRESSION;
MEDICAL COMORBIDITY; OLDER-ADULTS; SYMPTOMS; COSTS; DISABILITY;
ILLNESS; IMPACT
地址: WHO, Dept Measurement & Hlth Informat Syst, Geneva 27, Switzerland.
Asian Dev Bank, Econ & Res Dept, Manila, Philippines.
London Sch Hyg & Trop Med, London WC1, England.
通讯作者地址: Chatterji, S (通讯作者),WHO, Dept Measurement & Hlth Informat Syst, Geneva
27, Switzerland.
电子邮件地址: [email protected]
来源出版物页码计数: 8
第 70 条，共 81 条
标题: Resistance exercise in individuals with and without cardiovascular disease: 2007 update - A
scientific statement from the American Heart Association Council on Clinical Cardiology and
Council on Nutrition, Physical Activity, and Metabolism
作者: Williams, MA (Williams, Mark A.); Haskell, WL (Haskell, William L.); Ades, PA (Ades,
Philip A.); Amsterdam, EA (Amsterdam, Ezra A.); Bittner, V (Bittner, Vera); Franklin, BA
(Franklin, Barry A.); Gulanick, M (Gulanick, Meg); Laing, ST (Laing, Susan T.); Stewart, KJ
(Stewart, Kerry J.)
来 源 出 版 物 : CIRCULATION 卷 : 116 期 :
10.1161/CIRCULATIONAHA.107.185214 出版年: JUL 31 2007
5
页 :
572-584
DOI:
Web of Science 核心合集中的 "被引频次": 366
被引频次合计: 392
引用的参考文献数: 128
摘 要 : Prescribed and supervised resistance training (RT) enhances muscular strength and
endurance, functional capacity and independence, and quality of life while reducing disability in
persons with and without cardiovascular disease. These benefits have made RT an accepted
component of programs for health and fitness. The American Heart Association recommendations
describing the rationale for participation in and considerations for prescribing RT were published
in 2000. This update provides current information regarding the (1) health benefits of RT, (2)
impact of RT on the cardiovascular system structure and function, (3) role of RT in modifying
cardiovascular disease risk factors, (4) benefits in selected populations, (5) process of medical
evaluation for participation in RT, and (6) prescriptive methods. The purpose of this update is to
provide clinicians with recommendations to facilitate the use of this valuable modality.
文献类型: Review
作者关键词: AHA Scientific Statements; exercise; cardiovascular diseases
KeyWords Plus: CORONARY-ARTERY-DISEASE; RANDOMIZED CONTROLLED-TRIAL;
DAILY ENERGY-EXPENDITURE; RESTING BLOOD-PRESSURE; QUALITY-OF-LIFE;
OLDER-ADULTS; TRAINING IMPROVES; RISK-FACTORS; CARDIAC REHABILITATION;
MYOCARDIAL-INFARCTION
来源出版物页码计数: 13
第 71 条，共 81 条
标题: Antipsychotic drug use and mortality in older adults with dementia
作者: Gill, SS (Gill, Sudeep S.); Bronskill, SE (Bronskill, Susan E.); Normand, SLT (Normand,
Sharon-Lise T.); Anderson, GM (Anderson, Geoffrey M.); Sykora, K (Sykora, Kathy); Lam, K
(Lam, Kelvin); Bell, CM (Bell, Chaim M.); Lee, PE (Lee, Philip E.); Fischer, HD (Fischer, Hadas
D.); Herrmann, N (Herrmann, Nathan); Gurwitz, JH (Gurwitz, Jerry H.); Rochon, PA (Rochon,
Paula A.)
来源出版物: ANNALS OF INTERNAL MEDICINE 卷: 146 期: 11 页: 775-786 出版年: JUN
5 2007
Web of Science 核心合集中的 "被引频次": 233
被引频次合计: 236
引用的参考文献数: 69
摘要: Background: Antipsychotic drugs are widely used to manage behavioral and psychological
symptoms in dementia despite concerns about their safety.
Objective: To examine the association between treatment with antipsychotics (both conventional
and atypical) and all-cause mortality.
Design: Population -based, retrospective cohort study.
Setting: Ontario, Canada.
Patients: Older adults with dementia who were followed between 1 April 1997 and 31 March
2003.
Measurements: The risk for death was determined at 30, 60, 120, and 180 days after the initial
dispensing of antipsychotic medication. Two pairwise comparisons were made: atypical versus no
antipsychotic use and conventional versus atypical antipsychotic use. Groups were stratified by
place of residence (community or long-term care). Propensity score matching was used to adjust
for differences in baseline health status.
Results: A total of 27 259 matched pairs were identified. New use of atypical antipsychotics was
associated with a statistically significant increase in the risk for death at 30 days compared with
nonuse in both the community-dwelling cohort (adjusted hazard ratio, 1.31 [95% CI, 1.02 to 1.70];
absolute risk difference, 0.2 percentage point) and the long-term care cohort (adjusted hazard
ratio, 1.55 [CI, 1.15 to 2.07]; absolute risk difference, 1.2 percentage points). Excess risk seemed
to persist to 180 days, but unequal rates of censoring over time may have affected these results.
Relative to atypical antipsychotic use, conventional antipsychotic use was associated with a higher
risk for death at all time points. Sensitivity analysis revealed that unmeasured confounders that increase the risk for death could diminish or eliminate the observed associations.
Limitations: Information on causes of death was not available. Many patents did not continue their
initial treatments after 1 month of therapy. Unmeasured confounders could affect associations.
Conclusions: Atypical antipsychotic use is associated with an increased risk for death compared
with nonuse among older adults with dementia. The risk for death may be greater with
conventional antipsychotics than with atypical antipsychotics.
文献类型: Article
KeyWords Plus: RANDOMIZED CONTROLLED-TRIAL; PROPENSITY SCORE MODELS;
SUDDEN CARDIAC DEATH; QUALITY-OF-LIFE; NURSING-HOMES; ATYPICAL
ANTIPSYCHOTICS;
PSYCHOLOGICAL
SYMPTOMS;
ELDERLY-PATIENTS;
NEUROPSYCHIATRIC SYMPTOMS; VENOUS THROMBOEMBOLISM
地址: Queens Univ, Kingston, ON K7L 2V7, Canada.
Univ Toronto, Toronto, ON M4X 1K9, Canada.
Inst Clin Evaluat Sci, Toronto, ON M4X 1K9, Canada.
Harvard Univ, Sch Med, Boston, MA 02115 USA.
Harvard Univ, Sch Publ Hlth, Boston, MA 02115 USA.
Univ British Columbia, Vancouver, BC V5Z 1M9, Canada.
Univ Massachusetts, Sch Med, Meyers Primary Care Inst, Fallon Clin Fdn, Worcester, MA 01605
USA.
Univ Massachusetts, Sch Med, Meyers Primary Care Inst, Fallon Community Hlth Plan,
Worcester, MA 01605 USA.
通讯作者地址: Gill, SS (通讯作者),St Marys Lake Hosp, 340 Union St, Kingston, ON K7L 5A2,
Canada.
来源出版物页码计数: 12
第 72 条，共 81 条
标题: Acute coronary care in the elderly, Part I Non-ST-segment-elevation acute coronary
syndromes - A scientific statement for healthcare professionals from the American Heart
Association council on clinical cardiology - In collaboration with the society of geriatric
cardiology
作者: Alexander, KP (Alexander, Karen P.); Newby, K (Newby, Kristin); Cannon, CP (Cannon,
Christopher P.); Armstrong, PW (Armstrong, Paul W.); Gibler, WB (Gibler, W. Brian); Rich, MW
(Rich, Michael W.); Van de Werf, F (Van de Werf, Frans); White, HD (White, Harvey D.); Weaver,
WD (Weaver, W. Douglas); Naylor, MD (Naylor, Mary D.); Gore, JM (Gore, Joel M.); Krumholz,
HM (Krumholz, Harlan M.); Ohman, EM (Ohman, E. Magnus)
来 源 出 版 物 : CIRCULATION 卷 : 115 期 : 19
10.1161/CIRCULATIONAHA.107.182615 出版年: MAY 15 2007
页 :
2549-2569
DOI:
Web of Science 核心合集中的 "被引频次": 257
被引频次合计: 276
引用的参考文献数: 131
摘要: Background - Age is an important determinant of outcomes for patients with acute coronary
syndromes (ACS); however, community practice reveals a disproportionately lower use of
cardiovascular medications and invasive treatment even among elderly patients with ACS who
would stand to benefit. Reasons include limited trial data to guide the care of older adults and
uncertainty about benefits and risks, particularly with newer medications or invasive treatments
and in the setting of advanced age or complex health status.
Methods and Results - This 2-part American Heart Association scientific statement summarizes
evidence on patient heterogeneity, clinical presentation, and treatment of non-ST-elevation ACS in
relation to age (< 65, 65 to 74, 75 to 84, and >= 85 years). In addition, we review methodological
issues that influence the acquisition and application of evidence to the elderly patients treated in
community practice. A writing group combining international cardiovascular and geriatric
perspectives convened to summarize available data from trials (5 combined Virtual Coordinating
Center for Global Collaborative Cardiovascular Research [VIGOUR] trials) and 3 registries
(Global Registry of Acute Coronary Events, National Registry of Myocardial Infarction, and the
Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early
implementation of the American College of Cardiology/American Heart Association guidelines
national quality improvement initiative [CRUSADE]) to provide a conceptual framework for
future work in the care of the elderly with acute cardiac disease. Treatment for
non-ST-segment-elevation ACS ( Part I) and ST-segment-elevation myocardial infarction (Part II)
are reviewed. In addition, ethical considerations pertaining to acute care and secondary prevention
are considered ( Part II). The primary goal is to identify the areas in which sufficient evidence is
available to guide practice, as well as to determine areas that warrant further study. Although
treatment-related benefits should rise in an elderly population with high disease risk, data to assess
these benefits are limited, outcomes of importance vary, and heterogeneity among the elderly
increases treatment- related risks. Although a uniform approach to care in the oldest of the old is
unlikely, understanding the major contributors to benefits and risks from treatment will advance
the ability to apply guideline-based care in this subset of patients.
Conclusions - Although a few recent trials have described treatment effects in older patients,
others continue to exclude patients on the basis of age. Going forward, prospective trials should
enroll elderly subjects proportionate to their prevalence among the treated population to define
risk and benefit. Findings from age subgroup analyses should be reported in a consistent manner
across trials, including absolute and relative risks for efficacy and safety. Outcomes of particular
relevance to the elderly, such as quality of life, physical function, and independence, should also
be considered. Creatinine clearance should be calculated for every elderly patient to enable
appropriate dosing. In addition, physicians need an understanding of conditions unique to older
patients (eg, frailty, cognitive impairment) that influence treatment goals and outcomes. With
these efforts, treatment risks can be minimized, and benefits can be placed in the health context of
the elderly patient with ACS.
文献类型: Review
作者关键词: AHA scientific statements; acute coronary syndromes; elderly
KeyWords Plus: WAVE MYOCARDIAL-INFARCTION; MOLECULAR-WEIGHT HEPARIN;
PLATELET GLYCOPROTEIN IIB/IIIA; HIGH-RISK PATIENTS; PROSPECTIVE
RANDOMIZED MULTICENTER; TISSUE-PLASMINOGEN ACTIVATOR; EARLY
INVASIVE MANAGEMENT; PLACEBO-CONTROLLED TRIAL; QUALITY-OF-CARE;
UNSTABLE ANGINA
电子邮件地址: [email protected]
来源出版物页码计数: 21
第 73 条，共 81 条
标题: Acute coronary care in the elderly, Part II - ST-segment-elevation myocardial infarction - A
scientific statement for healthcare professionals from the American Heart Association council on
clinical cardiology - In collaboration with the Society of Geriatric Cardiology
作者: Alexander, KP (Alexander, Karen P.); Newby, LK (Newby, L. Kristin); Armstrong, PW
(Armstrong, Paul W.); Cannon, CP (Cannon, Christopher P.); Gibler, WB (Gibler, W. Brian); Rich,
MW (Rich, Michael W.); Van de Werf, F (Van de Werf, Frans); White, HD (White, Harvey D.);
Weaver, WD (Weaver, W. Douglas); Naylor, MD (Naylor, Mary D.); Gore, JM (Gore, Joel M.);
Krumholz, HM (Krumholz, Harlan M.); Ohman, EM (Ohman, E. Magnus)
来 源 出 版 物 : CIRCULATION 卷 : 115 期 : 19
10.1161/CIRCULATIONAHA.107.182616 出版年: MAY 15 2007
页 :
2570-2589
DOI:
Web of Science 核心合集中的 "被引频次": 216
被引频次合计: 231
引用的参考文献数: 129
摘要: Background - Age is an important determinant of outcomes for patients with acute coronary
syndromes. However, community practice reveals a disproportionately lower use of
cardiovascular medications and invasive treatment even among elderly patients who would stand
to benefit. Limited trial data are available to guide care of older adults, which results in
uncertainty about benefits and risks, particularly with newer medications or invasive treatments
and in the setting of advanced age and complex health status.
Methods and Results - Part II of this American Heart Association scientific statement summarizes
evidence on presentation and treatment of ST-segment-elevation myocardial infarction in relation
to age (< 65, 65 to 74, 75 to 84, and >= 85 years). The purpose of this statement is to identify
areas in which the evidence is sufficient to guide practice in the elderly and to highlight areas that
warrant further study. Treatment-related benefits should rise in an elderly population, yet data to
confirm these benefits are limited, and the heterogeneity of older populations increases
treatment-associated risks. Elderly patients with ST-segment-elevation myocardial infarction more
often have relative and absolute contraindications to reperfusion, so eligibility for reperfusion
declines with age, and yet elderly patients are less likely to receive reperfusion even if eligible.
Data support a benefit from reperfusion in elderly subgroups up to age 85 years. The selection of
reperfusion strategy is determined more by availability, time from presentation, shock, and
comorbidity than by age. Additional data are needed on selection and dosing of adjunctive
therapies and on complications in the elderly. A "one-size-fits-all" approach to care in the oldest
old is not feasible, and ethical issues will remain even in the presence of adequate evidence.
Nevertheless, if the contributors to treatment benefits and risks are understood,
guideline-recommended care may be applied in a patient-centered manner in the oldest subset of
patients.
Conclusions - Few trials have adequately described treatment effects in older patients with
ST-segment-elevation myocardial infarction. In the future, absolute and relative risks for efficacy
and safety in age subgroups should be reported, and trials should make efforts to enroll the elderly
in proportion to their prevalence among the treated population. Outcomes of particular relevance
to the older adult, such as quality of life, physical function, and independence, should also be
evaluated, and geriatric conditions unique to this age group, such as frailty and cognitive
impairment, should be considered for their influence on care and outcomes. With these efforts,
treatment risks can be minimized, and benefits can be placed within the health context of the
elderly patient.
文献类型: Review
作者关键词: AHA scientific statements; acute coronary syndromes; elderly
KeyWords
Plus:
TISSUE-PLASMINOGEN-ACTIVATOR;
LEFT-VENTRICULAR
DYSFUNCTION; SHOCK TRIAL REGISTRY; INTRAVENOUS THROMBOLYTIC
THERAPY; RANDOMIZED CONTROLLED-TRIAL; PLACEBO-CONTROLLED TRIAL;
COOPERATIVE CARDIOVASCULAR PROJECT; SCANDINAVIAN SIMVASTATIN
SURVIVAL; CONVERTING ENZYME-INHIBITORS; FRONT-LOADED ALTEPLASE
电子邮件地址: [email protected]
来源出版物页码计数: 20
第 74 条，共 81 条
标题: Comprehensive geriatric assessment for older patients with cancer
作者: Extermann, M (Extermann, Martine); Hurria, A (Hurria, Arti)
来源出版物: JOURNAL OF CLINICAL ONCOLOGY 卷: 25 期: 14 页: 1824-1831 DOI:
10.1200/JCO.2007.10.6559 出版年: MAY 10 2007
Web of Science 核心合集中的 "被引频次": 344
被引频次合计: 353
引用的参考文献数: 79
摘要: Purpose
During the last decade, oncologists and geriatricians have begun to work together to integrate the
principles of geriatrics into oncology care. The increasing use of a comprehensive geriatric
assessment (CGA) is one example of this effort. A CGA includes an evaluation of an older
individual's functional status, comorbid medical conditions, cognition, nutritional status,
psychological state, and social support; and a review of the patient's medications. This article
discusses recent advances on the use of a CGA in older patients with cancer.
Methods
In this article, we provide an update on the studies that address the domains of a geriatric
assessment applied to the oncology patient, review the results of the first studies evaluating the use
of a CGA in developing interventions to improve the care of older adults with cancer, and discuss
future research directions.
Results
The evidence from recent studies demonstrates that a CGA can predict morbidity and mortality in
older patients with cancer. Accumulating data show the benefits of incorporating a CGA in the
evaluation of older patients with cancer. Prospective trials evaluating the utility of a CGA to guide
interventions to improve the quality of cancer care in older adults are justified.
Conclusion
Growing evidence demonstrates that the variables examined in a CGA can predict morbidity and
mortality in older patients with cancer, and uncover problems relevant to cancer care that would
otherwise go unrecognized.
文献类型: Review
KeyWords Plus: CELL LUNG-CANCER; QUALITY-OF-LIFE; BREAST-CANCER;
PROSTATE-CANCER;
COGNITIVE
FUNCTION;
FUNCTIONAL
STATUS;
ELDERLY-PATIENTS;
ADJUVANT
CHEMOTHERAPY;
PROGNOSTIC-FACTORS;
PHYSICAL FUNCTION
地址: Univ S Florida, H Lee Moffitt Canc Ctr, Tampa, FL 33612 USA.
City Hope Natl Med Ctr, Duarte, CA USA.
通讯作者地址: Extermann, M (通讯作者),Univ S Florida, H Lee Moffitt Canc Ctr, 12902
Magnolia Dr, Tampa, FL 33612 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 8
第 75 条，共 81 条
标题: Correlates of physical health of informal caregivers: A meta-analysis
作者: Pinquart, M (Pinquart, Martin); Sorensen, S (Soerensen, Silvia)
来源出版物: JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES
AND SOCIAL SCIENCES 卷: 62 期: 2 页: P126-P137 出版年: MAR 2007
Web of Science 核心合集中的 "被引频次": 117
被引频次合计: 118
引用的参考文献数: 212
摘要: Effects of caregiving on physical health have received less theoretical and empirical
attention than effects on psychological health. This meta-analysis integrates results from 176
studies on correlates of caregiver physical health. Caregiver depressive symptoms had stronger
associations with physical health than did objective stressors. Higher levels of care recipient
behavior problems were more consistently related to poor caregiver health than were care receiver
impairment and intensity of caregiving. Higher age, lower socioeconomic status, and lower levels
of informal support were related to poorer health. Predictors of physical health are not identical to
predictors of psychological health. Associations of caregiving stressors with health were stronger
among older samples, dementia caregivers, and men. In sum, negative effects of caregiving on
physical health are most likely to be found in psychologically distressed caregivers facing
dementia-related stressors.
文献类型: Review
KeyWords Plus: QUALITY-OF-LIFE; ADULT DAUGHTER CAREGIVERS; FAMILY
CAREGIVERS; ALZHEIMERS-DISEASE; SPOUSE CAREGIVERS; DEPRESSIVE
SYMPTOMS;
DEMENTIA
PATIENTS;
SOCIAL
SUPPORT;
OLDER-ADULTS;
PARKINSONS-DISEASE
地址: [Pinquart, Martin] Friedrich Schiller Univ, Dept Dev Psychol, D-07743 Jena, Germany.
[Pinquart, Martin] Friedrich Schiller Univ, Ctr Appl Dev Sci, D-07743 Jena, Germany.
[Soerensen, Silvia] Univ Rochester, Sch Med & Dent, Rochester, NY 14627 USA.
通讯作者地址: Pinquart, M (通讯作者),Friedrich Schiller Univ, Dept Dev Psychol, Steiger 3
Haus 1, D-07743 Jena, Germany.
电子邮件地址: [email protected]
来源出版物页码计数: 12
第 76 条，共 81 条
标题: Enhancing the quality of life of dementia caregivers from different ethnic or racial groups A randomized, controlled trial
作者: Belle, SH (Belle, Steven H.); Burgio, L (Burgio, Louis); Burns, R (Burns, Robert); Coon, D
(Coon, David); Czaja, SJ (Czaja, Sara J.); Gallagher-Thompson, D (Gallagher-Thompson,
Dolores); Gitlin, LN (Gitlin, Laura N.); Klinger, J (Klinger, Julie); Koepke, KM (Koepke, Kathy
Mann); Lee, CC (Lee, Chin Chin); Martindale-Adam, J (Martindale-Adam, Jennifer); Nichols, L
(Nichols, Linda); Schulz, R (Schulz, Richard); Stahl, S (Stahl, Sidney); Stevens, A (Stevens,
Alan); Winter, L (Winter, Laraine); Zhang, S (Zhang, Song)
团体作者: Resources Enhancing Alzheimers
来源出版物: ANNALS OF INTERNAL MEDICINE 卷: 145 期: 10 页: 727-738 出版年: NOV
21 2006
Web of Science 核心合集中的 "被引频次": 250
被引频次合计: 251
引用的参考文献数: 28
摘要: Background: Caring for a family member with dementia is extremely stressful, contributes
to psychiatric and physical illness among caregivers, and increases the risk for caregiver death.
Finding better ways to support family caregivers is a major public health challenge.
Objective: To test the effects of a structured multicomponent intervention on quality of life and
clinical depression in caregivers and on rates of institutional placement of care recipients in 3
diverse racial or ethnic groups.
Design: Randomized, controlled trial.
Setting: In-home caregivers in 5 U.S. cities.
Participants: 212 Hispanic or Latino, 219 white or Caucasian, and 211 black or African-American
caregivers and their care recipients with Alzheimer disease or related disorders.
Intervention: Caregivers within each racial or ethnic group were randomly assigned to an
intervention or to a control group. The intervention addressed caregiver depression, burden,
self-care, and social support and care recipient problem behaviors through 12 in-home and
telephone sessions over 6 months. Caregivers in the control group received 2 brief "check-in"
telephone calls during the 6-month intervention.
Measurements: The primary outcome was a quality-of-life indicator comprising measures of
6-month caregiver depression, burden, self-care, and social support and care recipient problem
behaviors. Secondary outcomes were caregiver clinical depression and institutional placement of
the care recipient at 6 months.
Results: Hispanic or Latino and white or Caucasian caregivers in the intervention group
experienced significantly greater improvement in quality of life than those in the control group (P
< 0.001 and P = 0.037, respectively). Black or African-American spouse caregivers also improved
significantly more (P = 0.003). Prevalence of clinical depression was lower among caregivers in
the intervention group (12.6% vs. 22.7%; P = 0.001). There were no statistically significant
differences in institutionalization at 6 months.
Limitations: The study used only a single 6-month follow-up assessment, combined heterogeneous
cultures and ethnicities into a single group, and excluded some ethnic groups.
Conclusions: A structured multicomponent intervention adapted to individual risk profiles can
increase the quality of life of ethnically diverse dementia caregivers.
文献类型: Article
KeyWords Plus: SOCIAL SUPPORT; OLDER ADULTS; INTERVENTIONS; DEPRESSION;
METAANALYSIS; DESIGN; BURDEN; SCALE; REACH
地址: Univ Pittsburgh, Pittsburgh, PA 15260 USA.
Univ Alabama, Tuscaloosa, AL USA.
Univ Tennessee, Ctr Hlth Sci, Memphis, TN 38163 USA.
Geriatr Grp Memphis, Memphis, TN USA.
Arizona State Univ, Tempe, AZ USA.
Univ Miami, Miami, FL 33152 USA.
Stanford Univ, Sch Med, Palo Alto, CA 94304 USA.
Vet Affairs Palo Alto Hlth Care Syst, Palo Alto, CA USA.
Thomas Jefferson Univ, Philadelphia, PA 19107 USA.
NINR, Bethesda, MD 20892 USA.
NIH, Bethesda, MD 20892 USA.
Scott & White Mem Hosp & Clin, Temple, TX 76508 USA.
通讯作者地址: Schulz, R (通讯作者),Univ Pittsburgh, 121 Univ Pl,6th Floor, Pittsburgh, PA
15260 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 12
第 77 条，共 81 条
标题: Recommendations for a standard research assessment of insomnia
作者: Buysse, DJ (Buysse, Daniel J.); Ancoli-Israel, S (Ancoli-Israel, Sonia); Edinger, JD
(Edinger, Jack D.); Lichstein, KL (Lichstein, Kenneth L.); Morin, CM (Morin, Charles M.)
来源出版物: SLEEP 卷: 29 期: 9 页: 1155-1173 出版年: SEP 1 2006
Web of Science 核心合集中的 "被引频次": 342
被引频次合计: 349
引用的参考文献数: 178
摘要: Study Objectives: To present expert consensus recommendations for a standard set of
research assessments in insomnia, reporting standards for these assessments, and
recommendations for future research.
Participants: N/A.
Interventions: N/A.
Methods and Results: An expert panel of 25 researchers reviewed the available literature on
insomnia research assessments. Preliminary recommendations were reviewed and discussed at a
meeting on March 10-11, 2005. These recommendations were further refined during writing of the
current paper. The resulting key recommendations for standard research assessment of insomnia
disorders include definitions/diagnosis of insomnia and comorbid conditions; measures of sleep
and insomnia, including qualitative insomnia measures, diary, polysomnography, and actigraphy;
and measures of the waking correlates and consequences of insomnia disorders, such as fatigue,
sleepiness, mood, performance, and quality of life.
Conclusions: Adoption of a standard research assessment of insomnia disorders will facilitate
comparisons among different studies and advance the state of knowledge. These recommendations
are not intended to be static but must be periodically revised to accommodate further
developments and evidence in the field.
文献类型: Review
作者关键词: insomnia; diagnosis; polysomnography; sleep diary; actigraphy; questionnaires
KeyWords Plus: DSM-III-R; EPWORTH SLEEPINESS SCALE; MATCHED NORMAL
SLEEPERS; TEST-RETEST RELIABILITY; RESTLESS LEGS SYNDROME; SELF-REPORT
MEASURES; IV FIELD TRIAL; REPORT QIDS-SR; PSYCHIATRIC-DISORDERS;
OLDER-ADULTS
地址: Univ Pittsburgh, Sch Med, Dept Psychiat, Pittsburgh, PA USA.
Univ Calif San Diego, Dept Psychiat, San Diego, CA 92103 USA.
Vet Affairs San Diego Healthcare Syst, San Diego, CA USA.
Vet Adm Hosp, Dept Psychol, Durham, NC USA.
Duke Univ, Dept Psychol, Durham, NC 27706 USA.
Univ Alabama, Dept Psychol, Tuscaloosa, AL 35487 USA.
Univ Laval, Dept Psychol, Quebec City, PQ, Canada.
通讯作者地址: Buysse, DJ (通讯作者),3811 OHara St, Pittsburgh, PA 15213 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 19
第 78 条，共 81 条
标题: Meaningful change and responsiveness in common physical performance measures in older
adults
作者: Perera, S (Perera, S); Mody, SH (Mody, SH); Woodman, RC (Woodman, RC); Studenski,
SA (Studenski, SA)
来源出版物: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 卷: 54 期: 5 页:
743-749 DOI: 10.1111/j.1532-5415.2006.00701.x 出版年: MAY 2006
Web of Science 核心合集中的 "被引频次": 485
被引频次合计: 490
引用的参考文献数: 28
摘要: OBJECTIVES: To estimate the magnitude of small meaningful and substantial individual
change in physical performance measures and evaluate their responsiveness. DESIGN: Secondary
data analyses using distribution- and anchor-based methods to determine meaningful change.
SETTING: Secondary analysis of data from an observational study and clinical trials of
community-dwelling older people and subacute stroke survivors.
PARTICIPANTS: Older adults with mobility disabilities in a strength training trial (n = 100),
subacute stroke survivors in an intervention trial (n = 1.00), and a prospective cohort of
community-dwelling older people (n = 492).
MEASUREMENTS: Gait speed, Short Physical Performance Battery (SPPB), 6-minute-walk
distance (6MWD), and self-reported mobility.
RESULTS: Most small meaningful change estimates ranged from 0.04 to 0.06 m/s for gait speed,
0.27 to 0.55 points for SPPB, and 19 to 22 m for 6MWD. Most substantial change estimates
ranged from 0.08 to 0.14 m/s for gait speed, 0.99 to 1.34 points for SPPB, and 47 to 49 m for
6MWD. Based on responsiveness indices, per-group sample sizes for clinical trials ranged from
13 to 42 for substantial change and 71 to 161 for small meaningful change.
CONCLUSION: Best initial estimates of small meaningful change are near 0.05 m/s for gait
speed, 0.5 points for SPPB, and 20 m for 6MWD and of substantial change are near 0.10 m/s for
gait speed, 1.0 point for SPPB, and 50 m for 6MWD. For clinical use, substantial change in these
measures and small change in gait speed and 6MWD, but not SPPB, are detectable. For research
use, these measures yield feasible sample sizes for detecting meaningful change.
文献类型: Article
作者关键词: meaningful change; responsiveness; physical performance measures; gait speed;
SPPB; 6-minute walk
KeyWords Plus: 6-MINUTE WALK TEST; QUALITY-OF-LIFE; HEALTH-STATUS;
CLINICAL-PRACTICE; TRIAL; EXERCISE; MOBILITY; THERAPY; DECLINE; BALANCE
地址: Univ Pittsburgh, Div Geriatr Med, Pittsburgh, PA 15213 USA.
Univ Pittsburgh, Dept Biostat, Pittsburgh, PA 15213 USA.
Dept Vet Affairs Hosp, Geriatr Res Educ & Clin Ctr, Pittsburgh, PA USA.
Ortho Biotech LLC, Clin Affairs, Bridgewater, NJ USA.
通讯作者地址: Perera, S (通讯作者),Univ Pittsburgh, Div Geriatr Med, 3471 5th Ave,Suite 500,
Pittsburgh, PA 15213 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 7
第 79 条，共 81 条
标题: Physical activity and survival after breast cancer diagnosis
作者: Holmes, MD (Holmes, MD); Chen, WY (Chen, WY); Feskanich, D (Feskanich, D);
Kroenke, CH (Kroenke, CH); Colditz, GA (Colditz, GA)
来源出版物: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 卷: 293 期:
20 页: 2479-2486 DOI: 10.1001/jama.293.20.2479 出版年: MAY 25 2005
Web of Science 核心合集中的 "被引频次": 691
被引频次合计: 704
引用的参考文献数: 57
摘要: Context Physical activity has been shown to decrease the incidence of breast cancer, but the
effect on recurrence or survival after a breast cancer diagnosis is not known.
Objective To determine whether physical activity among women with breast cancer decreases
their risk of death from breast cancer compared with more sedentary women.
Design, Setting, and Participants Prospective observational study based on responses from 2987
female registered nurses in the Nurses' Health Study who were diagnosed with stage I, II, or III
breast cancer between 1984 and 1998 and who were followed up until death or June 2002,
whichever came first.
Main Outcome Measure Breast cancer mortality risk according to physical activity category (<3,
3-8.9, 9-14.9,15-23.9, or &GE; 24 metabolic equivalenttask [MET] hours per week).
Results Compared with women who engaged in less than 3 MET-hours per week of physical
activity, the adjusted relative risk (RR) of death from breast cancer was 0.80 (95% confidence
interval [CI], 0.60-1.06) for 3 to 8.9 MET-hours per week; 0.50 (95% Cl, 0.31-0.82) for 9 to 14.9
MET-hours per week; 0.56 (95% Cl, 0.38-0.84) for 15 to 23.9 MET-hours per week; and 0.60
(95% Cl, 0.40-0.89) for 24 or more MET-hours per week (P for trend =.004). Three MET-hours is
equivalent to walking at average pace of 2 to 2.9 mph for 1 hour. The benefit of physical activity
was particularly apparent among women with hormone-responsive tumors. The RR of breast
cancer death for women with hormone-responsive tumors who engaged in 9 or more MET-hours
per week of activity compared with women with hormone-responsive tumors who engaged in less
than 9 MET-hours per week was 0.50 (95% Cl, 0.34-0.74). Compared with women who engaged
in less than 3 MET-hours per week of activity, the absolute unadjusted mortality risk reduction
was 6% at 10 years for women who engaged in 9 or more MET-hours per week.
Conclusions Physical activity after a breast cancer diagnosis may reduce the risk of death from
this disease. The greatest benefit occurred in women who performed the equivalent of walking 3
to 5 hours per week at an average pace, with little evidence of a correlation between increased
benefit and greater energy expenditure. Women with breast cancer who follow US physical
activity recommendations may improve their survival.
文献类型: Article
KeyWords Plus: RECEIVING ADJUVANT CHEMOTHERAPY; BODY-MASS INDEX;
NATIONAL DEATH INDEX; QUALITY-OF-LIFE; POSTMENOPAUSAL WOMEN;
UNITED-STATES; OLDER-ADULTS; WEIGHT-GAIN; RISK; EXERCISE
地址: Brigham & Womens Hosp, Dept Med, Channing Lab, Boston, MA USA.
Harvard Univ, Sch Med, Boston, MA USA.
Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA.
通讯作者地址: Holmes, MD (通讯作者),Channing Labs, 181 Longwood Ave, Boston, MA 02115
USA.
电子邮件地址: [email protected]
来源出版物页码计数: 8
第 80 条，共 81 条
标题: Exercise and well-being: a review of mental and physical health benefits associated with
physical activity
作者: Penedo, FJ (Penedo, FJ); Dahn, JR (Dahn, JR)
来 源 出 版 物 : CURRENT OPINION IN PSYCHIATRY 卷 : 18 期 : 2 页 : 189-193 DOI:
10.1097/00001504-200503000-00013 出版年: MAR 2005
Web of Science 核心合集中的 "被引频次": 421
被引频次合计: 431
引用的参考文献数: 37
摘要: Purpose of review This review highlights recent work evaluating the relationship between
exercise, physical activity and physical and mental health. Both cross-sectional and longitudinal
studies, as well as randomized clinical trials, are included. Special attention is given to physical
conditions, including obesity, cancer, cardiovascular disease and sexual dysfunction. Furthermore,
studies relating physical activity to depression and other mood states are reviewed. The studies
include diverse ethnic populations, including men and women, as well as several age groups (e.g.
adolescents, middle-aged and older adults).
Recent findings Results of the studies continue to support a growing literature suggesting that
exercise, physical activity and physical-activity interventions have beneficial effects across several
physical and mental-health outcomes. Generally, participants engaging in regular physical activity
display more desirable health outcomes across a variety of physical conditions. Similarly,
participants in randomized clinical trials of physical-activity interventions show better health
outcomes, including better general and health-related quality of life, better functional capacity and
better mood states.
Summary The studies have several implications for clinical practice and research. Most work
suggests that exercise and physical activity are associated with better quality of life and health
outcomes. Therefore, assessment and promotion of exercise and physical activity may be
beneficial in achieving desired benefits across several populations. Several limitations were noted,
particularly in research involving randomized clinical trials. These trials tend to involve limited
sample sizes with short follow-up periods, thus limiting the clinical implications of the benefits
associated with physical activity.
文献类型: Article
作者关键词: exercise; health; physical activity
KeyWords Plus: QUALITY-OF-LIFE; BODY-MASS INDEX; BREAST-CANCER;
OLDER-ADULTS; WOMEN; DISEASE; TRIAL; RISK; REHABILITATION; PREVENTION
地址: Univ Miami, Dept Psychol, Coral Gables, FL 33124 USA.
Univ Miami, Sylvester Comprehens Canc Ctr, Coral Gables, FL 33124 USA.
Miami Vet Affairs Med Ctr, Miami, FL USA.
通讯作者地址: Penedo, FJ (通讯作者),Univ Miami, Dept Psychol, POB 248185, Coral Gables,
FL 33124 USA.
电子邮件地址: [email protected]
来源出版物页码计数: 5
第 81 条，共 81 条
标题: Measuring the psychological outcomes of falling: A systematic review
作者: Jorstad, EC (Jorstad, EC); Hauer, K (Hauer, K); Becker, C (Becker, C); Lamb, SE (Lamb,
SE)
团体作者: ProFaNE Grp
来源出版物: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 卷: 53 期: 3 页:
501-510 DOI: 10.1111/j.1532-5415.2005.53172.x 出版年: MAR 2005
Web of Science 核心合集中的 "被引频次": 152
被引频次合计: 157
引用的参考文献数: 55
摘要: The objectives were to identify fall-related psychological outcome measures and to
undertake a systematic quality assessment of their key measurement properties. A Cochrane
review of fall-prevention interventions in older adults was used to identify fall-related
psychological measurements. PubMed, CINAHL, and PsycINFO were systematically searched to
identify instruments not used in trials and papers reporting the methodological quality of relevant
measures. Reference lists of articles were searched for additional literature, and researchers were
contacted. Two reviewers undertook quality extraction relating to content, population, reliability,
validity, responsiveness, practicality, and feasibility. Twenty-five relevant papers were identified.
Twenty-three measures met the inclusion criteria: six single-item questions, Falls Efficacy Scale
(FES), revised FES, modified FES, FES-UK, Activities-specific Balance and Confidence Scale
(ABC), ABC-UK, Confidence in maintaining Balance Scale, Mobility Efficacy Scale, adapted
FES, amended FES, Survey of Activities and Fear of Falling in the Elderly (SAFFE), University
of Illinois at Chicago Fear of Falling Measure, Concern about Falling Scale, Falls Handicap
Inventory, modified SAFFE, Consequences of Falling Scale, and Concern about the Consequences
of Falling Scale. There is limited evidence about the measurement properties of single-item
measures. Several multiitem measures obtained acceptable reliability and validity, but there is less
evidence regarding responsiveness, practicality, and feasibility. Researchers should select
measures based on the constructs they intend to study. Further research is needed to establish and
compare the instruments' measurement properties.
文献类型: Article
作 者 关 键 词 : balance confidence; fall-related self-efficacy; fear of falling; measurement
properties; systematic review
KeyWords Plus: QUALITY-OF-LIFE; SELF-EFFICACY; BALANCE
ELDERLY-PATIENTS; HIP FRACTURE; OLDER-ADULTS; FEAR;
MOBILITY; RESTRICTION
CONFIDENCE;
COMMUNITY;
地址: Univ Warwick, Warwick Med Sch, Warwick Emergency Care & Rehabil, Ctr Primary Hlth
Care Studies, Coventry CV4 7AL, W Midlands, England.
Univ Heidelberg, Bethanien Krankenhaus, Res Dept, Heidelberg, Germany.
Robert Bosch Krankenhaus, Dept Geriatr Rehabil, Stuttgart, Germany.
Univ Ulm, Geriatr Ctr, Ulm, Germany.
John Radcliffe Hosp, Oxford Radcliffe Hosp NHS Trust, Kadoorie Crit Care Res Ctr, Oxford OX3
9DU, England.
通讯作者地址: Jorstad, EC (通讯作者),Univ Warwick, Warwick Med Sch, Warwick Emergency
Care & Rehabil, Ctr Primary Hlth Care Studies, Coventry CV4 7AL, W Midlands, England.
电子邮件地址: [email protected]
来源出版物页码计数: 10