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KASPER/MOLTZAN QUIZ October 30, 2007 Dr. El-Gabalawy’s Connective Tissue Disease Dr. Targownik’s PUD Dr. Silver’s Psorias Dr. Bellas’s Post-Op Fever Dr. Karpinski’s Renal Transplant Dr. Wiebe’s Med Recs Reading Article: The Use of DXA Scans in the Diagnosis and Treatment of Osteoporosis Reading Article: Sarcoid Heart Disease 1) Which of the following is not associated with scleroderma: a) telangiectasia b) small bowel bacterial overgrowth c) calcinosis d) increased risk of malignancy e) cardiac conduction defects 2) Which of the following investigations are rarely useful in the diagnosis and management of polymyositis: a) MRI b) EMG c) muscle biopsy d) abdominal CT scanning e) pulmonary function tests 3) Which of the following is not an acceptable gastroprotective strategy in high-risk NSAID users: a) PPIs b) H2-receptor antagonists c) Misoprostol d) COX-2 inhibitors e) Avoidance of NSAIDs 4) Which of the following is TRUE: a) All dyspeptic patients who do not respond to a trial of empiric antisecretory therapy and HP eradication should undergo upper endoscopy b) A normal upper endoscopy may improve patient satisfaction in patients with non-ulcer dyspepsia c) Eradication of HP in HP+ patients is associated with a 50% absolute reduction in dyspepsia when compared to placebo d) PPIs are not effective for patients with non-ulcer dyspepsia e) The majority of patients with dyspeptic symptoms will have underlying peptic ulcer disease 5) Which medication is containdicated in the treatment of psoriasis? a) cyclosporin b) soriatiane c) prednisone d) mycophenolate mofetil e) methotrexate 6) True or false: Methotrexate alters the progression of joint disease in psoriasis 7) Which of the following medications can exacerbate psoriasis a) metoprolol b) amoxicillin c) hydroxychloroquine d) a and c e) all of the above 8) Which of the following statements about Post-op fever is incorrect? a) b) c) d) 9) Which order best represents the frequency of infectious etiologies of post-op fever: a) b) c) d) 10) The incidence of post-op fever is ~50% ~90% of fevers occurring within 48 hours of OR have a non-infectious cause ~90% of fevers occurring >4 days post-op have an infectious cause >50% of cases of post-op fever are caused by atelectasis Wound > Pneumonia > UTI UTI > Pneumonia > Wound Wound > UTI > Pneumonia Pneumonia > UTI > Wound Which of the following statements about post-op delirium is correct? a) b) c) d) It is uncommon (incidence < 5%) It is overdiagnosed It does not affect post-op mortality It is associated with decreased functional recovery 11) Which of the following represents an immunologic contraindication to transplantation? a) Blood group 0 recipient and blood group AB donor b) Donor specific HLA antibodies present in the recipient c) 0 of 6 HLA match between donor and recipient d) all the above e) 1 and 2 12) Which of the following medications does not increase calcineurin inhibitor levels (i.e. CnI; cyclosporine or tacrolimus)? a) erythromycin b) rifampin c) ketoconazole d) diltiazem 13) Which of the following most accurately reflects current outcomes in living donor kidney transplantation? a) 1yr graft survival 98%, acute rejection rate in first year ~10%, graft half-life 20-25 years b) 1yr graft survival 95%, acute rejection rate in first year ~20%, graft half-life 15-20 years c) 1yr graft survival 90%, acute rejection rate in first year ~30%, graft half-life 10-15 years 14) If the patient does not have any medications, what do you record on the Med Rec form? 15) If you complete the Medication Reconciliation for a patient and you do the H&P for the same patient, are you writing the home medications in both places? 16) What should you record in the patient’s H&P if you have completed a Medication Reconciliation Form? 17) Which of the following is NOT true about cardiac sarcoidosis? a) serum angiotensin converting enzyme activity can be used to help make the diagnosis b) if the patient is asymptomatic the granulomas in the heart will likely resolve on their own within two years c) MRI is the imaging modality that is the most sensitive to make the diagnosis d) cardiac sarcoidosis is a diagnosis of exclusion and other autoimmune diseases need to be ruled out Answers: 1) 2) 3) 4) 5) 6) 7) 8) 9) 10) 11) 12) 13) 14) 15) 16) 17) d d b b c false d d c d e – complete HLA mismatch transplants are routinely performed, but ABO incompatibility and a positive cross-match are absolute contraindications Answer is b - rifampin will increase P4503A4 activity enhancing CnI metabolism hence reducing drug levels, the other 3 compete with CnI for metabolism and increase CnI levels a You do not leave the form blank. You document that patient does not have any meds. no You should record: See Med Rec Form for home meds. a