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Week 1
An introduction to genetics and learning the lingo.
Lecture 1
Biotechnology News
Inheritance and Reproduction News
DNA and Destiny
Epigenetics
Imprinting
DNA Packaging
Chromosomes
Nucleosomes and Chromatin
Human genes
Normal Human Karyotype
Human Genome Project
The Central Dogma
Gene Expression and Cell Differentiation
The Structure of Proteins
Four Levels of Protein Structure
Hemoglobin
Sickle-cell Disease
Lecture 2
mRNA Has Specialized Regions with Important Functions
mRNA Has Specialized Regions with Important Functions 2
The promoter
Control of Gene Expression
Control of Gene Expression 2
Control of Gene Expression 3
mRNA is Translated in the 5' to 3’ Direction
DNA and Protein are Colinear
Activators
Activators 2
Amino Acids and Proteins
Epigenetics Defined
Epigenetics Defined 2
Epigenetics in Action
Methylation
Genomic Imprinting
Genomic Imprinting 2
Genomic Imprinting 3
Genomic Imprinting 4
Lifestyle and Methylation Patterns: Nutrition
Lifestyle and Methylation Patterns: Exercise
Lifestyle and Methylation Patterns: Smoking
Lifestyle and Methylation Patterns: Smoking 2
Lecture 3
What Causes Mutations
DNA and Mutations
Frame-shift Mutations
Frame-shift Mutation 2
The Central Dogma In Detail
For Proteins, Form Shapes Function
Lecture 4
Allele Definition
Allele Definition 2
Homologous Chromosomes
Homologous Chromosomes 2
Variation In Gene Expression
Penetrance and Expressivity
Human Polygenic Traits
Pleiotropy
Pleiotropic and Polygenic Traits
Epistasis
Lecture 5
Hormone Action
Serotonin
Irritable Bowel Syndrome
“The Violence Gene”
“Warrior Gene”
Neurons
Neurotransmitters
Alcoholic Flies
Sexually Spurned Flies Turn to the Bottle
Lecture 6
Comparative Genomics
Knockout Mice
Knockout Mice 2
The Human Genome Project Information
Developmental Genetics
Hox Genes
Eyeless Gene
PAX6
RNA Interference
Drosophila as Human Disease Models: Drug Discovery
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