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REVIEW OF LITERATURE: Review of related literature is an important aspect of any research. It involves systematic synoptic understanding of the research works already conducted in the same field over a period of time. It provides some insight regarding strong points and limitations of the previous studies and enables the researcher to improve his own investigation. All available literature concerning the problem at hand must necessarily be surveyed and examined before a definition of the research problem is given. This means that the researcher must be well conversant with relevant theories in the field, reports and records also all other relevant literature. Review of literature is done to find out what data and other materials are available for operational purposes knowing what data are available often serves to narrow the problem itself as well as the technique that might be lose. This would also help a researcher to know if there are certain problems under study are inconsistent with each other and so on. Studies on related problems are useful for indicating the type of difficulties that may be encountered in the present study as also the possible analytical shortcomings. Health and nutrition are the most important contributing factors for human resource development. Good nutrition is the fundamental basic requirement for positive health, functional efficiency and productivity. Nutrition science provides abundant evidence of the importance of nutrition in not only promoting proper physical growth and development, but also in ensuring adequate immuno-competence and cognitive development. Now a days overweight and obesity as an important public health problem in developing as well as in developed countries. So it is very important to know about the factors responsible for the obesity and the consequence and also the prevalence of obesity. So various surveys are being conducted by different researchers. Some are given below. 31 2.1 ANTHROPOMETRY AND OBESITY: Valsamakis, et al. (2004) found in their study the association of simple anthropometric measures of obesity with visceral fat and metabolic syndrome in male Caucasian and indo Asian subjects. The aims of this study were first; to investigate the relationship between simple anthropometric measures of obesity with visceral fat as assessed by a single slice magnetic resonance imaging (MRI) can in patients attending a hospital clinic. Second is to determine which anthropometric measure best relates to the adverse metabolic profile of the metabolic syndrome. 41 male subjects were studied by MRI scan to measure visceral fat at L 4/ L5 level and to investigate its relationship with simple anthropometric measures. 83 male subjects were studied to determine which anthropometric measures best predicts the metabolic complications of obesity in the setting of a hospital clinic. It was found that waist circumference was the best anthropometric measurement that correlated with MRI visceral fat mass assessed at L 4/ L5 in 41 subjects who had an MRI scan amongst the variables which also included age, BMI, Sagittal diameter and ethnicity. Sagittal diameter better predicts the adverse metabolic profile of the metabolic syndrome. Although there is considerable variation in abdominal fat topography between ethnic groups and also within populations, sagittal diameter assessment is a technique that is simple and best predicts the metabolic syndrome. Kim et al, (2004), conducted a study on BMI and metabolic disorders in South Korean adults. The prevalence of overweight, obesity and metabolic disorders and their relationship with body mass index (BMI) were studied in South Korean adults. The appropriate BMI categories for overweight and obesity for Koreans were evaluated. The 1998 Korea national Health and Nutrition examination survey provided data on body weight, height, fasting serum glucose, triacylglycerol, total, low density lipoprotein and high density lipoprotein cholesterol, and blood pressure, various other questions that were incorporated into theirs study. A total of 39060 persons over the age of one year from 12283 households participated in the Health and Nutrition interview survey. Of these 10876 people over the age of 10 years old participated in the health examination, also 7692 adults over the 32 age of 20 years. The overweight and obesity prevalence rates were low among Korean adults. 23.4% and 1.7% in men and 24.9% and 3.2% in women, respectively. But the prevalence of diabetes, hypertension, abnormal concentration of serum triacylglycerols and total, low density lipoprotein and high density lipoprotein cholesterol were high at 10.5%, 27.1%, 29.0%, 34.5%, 28.4%, and 37.4% respectively. These disorders were age dependent and there was a strong linear relationship between BMI and the disorders. Marild, et al, (2004) carried a study on prevalence trends of obesity and overweight among 10 year old children in western Sweden and the relationship with parental body mass index. A cross sectional study of 10 y old children born in 1990, was performed during September 2000 to June 2001 at school health centers in three communities in the western part of Sweden. Evaluation was performed in 6311 children or 81% of the target population. Data from a cohort of children, born in 1974, who form the national growth charts, were available for comparison. The mean body mass index was 17.9 kg/m2 in 10 year old children born in 1990 and 17.0 kg/m 2 for 10 year old born in 1974. Of the 10 years old children in 2000-2001, born in 1990, 18% were overweight and 2.9% obese, which corresponds to a two fold increase in presence of overweight and a four fold increase in presence of obesity among 10 year old children from 1984 to 2000. There was a significant correlation between parental and children body mass index. The prevalence of obesity and being overweight appeared to be higher in children whose parents did not participate in the study. Parental ponderosity or reluctance to participate in the study was related to a higher prevalence of being overweight or obese in the children. There is a need for the health care system to recognize the threats to the health of the population of this new epidemic and initiate preventive measures and treatment programmes. Oliveira, et al., (2004) studied the relationships in women between body mass index and the intravascular metabolism of chylomicrone like emulsions. Four groups of 10 normolipidemic non-diabetic women at the normal (BMI<25 kg/m2), preobese (BMI 25-30 Kg/m2), obese (BMI 30-40 kg/m2) and morbid obese (BMI >40 kg/m2). Chylomicron metabolism was 33 studied using a method with triacylglycerols studied using a method with triacylglycerol rich emulsions that mimic chylomicron. The chylomicron like emulsion doubly labeled the chylomicron like emulsion doubly labeled with 3H –triolein (To) and 14c cholesterol – oleate (Co) was intravenously injected to calculate the plasma fractional clearance rates (FCR, in mon -1) by a compartmental analysis model. FCR- To mirror both the lipolysis from lipoprotein lipase that the emulsion suffers while still in the circulation and the triacylglycerols portion that is not broken down and is removed from the plasma together with the remnant particles. FCR –To do not differ among the 4 groups. The lipolysis index was positively correlated with BMI. On the other hand FCR to progressively diminish from the normal to the morbid obese groups and there was a negative correlation between FCR Co and BMI. In obesity the capacity to break down chylomicron triacylglycerols by lipoprotein lipase in vivo increases but the ability the organisms to remove the resulting chylomicron remnants particles progressively diminishes as the BMI rises. Lara Esqueda, et al., (2004) observed from their study that the body mass index is a less sensitive tool for detecting cases with obesity associated co morbidities in short stature subjects. Information was obtained from 119975 subjects of a cardiovascular risk factors detection programme. Standardized questionnaires were used. Capillary glucose and cholesterol concentrations were measured. Diabetes, arterial hypertension and hypercholesterolemia were measured diabetes; arterial hypertension and hypercholesterolemia wee selected as end points. Sensitivity, specificity and the likelihood ratio for several BMI thresholds were calculated. ROC curves were constructed to identify the BMI cutoff points with best diagnostic performance. The area under the curve (AUC) was used to assess the proficiency of BMI. Short stature (heights<=150 cm for women or <=160 cm for men) was found in 24854 subjects (20.7%). These cases had a higher prevalence of type 2 diabetes and arterial hypertension even after adjusting for confounding variables. In addition, the frequency of abnormalities was higher even at the lowest BMI values, the prevalence increased in direct proportion with the BMI, but at a lower rate compared to cases with normal 34 4stature. The prevalence of obesity associated co morbidities is higher in subjects with short stature compared to those without it. The proficiency of BMI as the diagnostic tool is poor in short stature subjects. Halkjer, et al., (2004) observed in their study the food and drinking patterns as predictors at 6 year BMI adjusted changes in waist circumference. The subjects were 2300 middle aged men and women with repeated measurements of dietary intake, BMI and WC from 1982 to 1993. Intakes from ten food groups and from coffee, tea, wine, beer and spirits were assessed. Gender specific food factors were identified by factor analyses. Multiple linear regression analyses were done before and after adjustment for concurrent changes in BMI. A high intake of potatoes seemed to prevent again in WC for men, while a higher intake of refined bread was associated with gain in WC for women. The association persisted for refined bread, but not for potatoes, after adjustment for concurrent BMI changes. Among women, high intakes of beer and spirits were associated with gain in WC in both models. A higher intake of coffee for women and moderate to high intake of tea for men, while associated with gain in WC, but the associations were weakened, especially for men after adjustment for BMI changes. None of the food factors was associated with WC changes. Hengleng, et al., (2004) conducted a study on body mass index and factors related to overweight among women workers in electronic factories in peninsular Malaysia. Factors related to overweight were examined, in a cross sectional survey that included 1612 women workers from 10 large electronics assembly factories in peninsular Malaysia. Heights and weights were taken to calculate the Body Mass Index (BMI). Weights and BMI increased with increasing age. After adjusting for age, odds ratios for overweight were significantly raised for married women in relation to not married women, lower secondary education in relation to higher than upper secondary educations, monthly income RM 800-999 and RM 1000 in relation to < RM 600, working in rotating shifts that included night shifts and not staying in hostels. The overall prevalence of overweight was 37.4% and over all mean BMI were 24.25.4 kg/m2. Prevalence of overweight and mean BMI for younger age groups were similar to Malay women in the country wide 35 representative National health and Morbidity survey II, but the older age groups in this study had higher overweight prevalence and mean BMI than the National sample-Electronics women workers face a higher risk of overweight and is an important groups for nutrition intervention. Haeffner, et al., (2004) assessed the association between maternal smoking in pregnancy and BMI in young adults after adjusting for possible confounders. A longitudinal study was carried out based on a birth cohort born in 1978/79 in Ribeirao Preto; Brazil. Weight and length at birth were measured and mothers were asked to answer a standardized questionnaire shortly after delivery BMI was obtained at the time of compulsory military draft at the age of 18 years from a sub-sample of 1191 males corresponding to 36% of the original sample. The variation in BMI according to maternal smoking adjusting for weight and length at birth, maternal age, gestational age, maternal schooling, marital status, birth order and conscripts education level in a multiple linear regression model were assessed. The prevalence of maternal smoking was 25%. Conscript’s BMI in mothers who smoked during pregnancy was 0.71 kg/m2 higher than among those whose mothers did not smoke, after adjustment. Birth weight and maternal schooling were slightly associated with BMI in adult’s life. BMI was strongly associated with maternal smoking in pregnancy and remained so after adjustment for a series of variables. Hulanicka, et al., (2004) conducted a study on adiposity at the age of 50 in relation to BMI and WHR in childhood and adolescence. This study concerned groups of people all born in 1953, who as randomly selected sample of 7 years old children from city of Wroclaw, were examined once a year till their physical maturity. Longitudinally collected anthropometric data are available for 243 males and 269 females. Presently where the members of the groups are fifty an extensive medical examination and anthropometric measurements have been completed. Also the subjects had filled up questionnaire. This pertains to many information concerning their family situation, private and professional activities and SES. The material comprises 120 women and 116 men. For males correlation of BMI at the age of 50 with BMI at every age bracket between ages 8-18 is significant and 36 steadily increases. But in females this is only till the beginning of puberty. Correlation between BMI at the age of 50 and BMI at each age’s bracket between 11 and 17 is almost same. In men adult adiposity level (BMI and central body fat distribution (WHR) seem to be decided already at adolescence. In females the significant correlation of the tempo of maturation with the level of adiposity in children hood and adolescence disappears in adulthood. Taeymans, et al., (2004) conduct a study to detect anthropometric variables as predictors of body composition at ages 17/18 and 30 from age 6 onwards and to investigate their predictive value based on longitudinal data. The sample (n=67) was a part of a larger longitudinal growth study called LEGS. The original sample consisted of five cohorts and totaled 525 children. They were followed anthropometrically from kindergarten age to age 18. At the age 30 a sample of 37 male and 30 females’ subjects was measured again. Multiple step wise linear regression was used with anthropometric characteristics at each age separately from age 6 on as predictors for obesity or overweight characteristics measured at age 30, such as BMI, body weight and sum of skin folds. In men, moderate correlations were found between skin fold thickness measurements at ages 6 to 13 and BMI at age 30. Body weight in men can only be used as prediction for BMI 30 during the growth spurt period, while in women body weight has predictive value for BMI 30 at all ages. In men there is no skeletal growth related variables as possible predictor of BMI 30 while skin fold thicknesses have predictive value only in children hood and puberty. Mesomorphy is possible predictor from age 10 on. Ectomorphy is negatively related to BMI 30, as expected. Deriemaeker, et al., (2004) conducted a study on anthropometric measures of central obesity and cardiovascular risk factors in overweight youth. The subjects (94 girls and 87 boys) were between 2.2 and 17 years of age with a BMI>P 97. Plasma levels of glucose, cholesterol, triglycerides, HDL cholesterol, uric acid, fibrinogen, homocysteine, serum insulin by standards methods. LDL cholesterol, Homo insulin resistance index (HI) and triglycerides/ HDL cholesterol ratio (TH) was calculated. ST (using 37 Harpender Caliper) and waist C and upper arm C (using a adopted tape) were evaluated by two trained observers. In overweight girls and boys most measures of insulin resistance are related to increased central body fat, as assessed, by waist circumference. No additional information could be retrieved from skin fold or other anthropometric measurements in the metabolic evaluation of cardiovascular risks. Tufano et al., (2004) observed the anthropometric, hormonal and biochemical differences in lean and obese women before and after menopause. The menopausal status is associated with an increased risk of metabolic and cardiovascular diseases. 24 normal weight premenopausal, 24 normal weight postmenopausal, 24 obese premenopausal and 20 obese post menopausal women were taken for the study. All subjects were non smokers and free from hypertension, diabetes or impaired glucose tolerance. Anthropometric parameters, body composition, 17-a- Estradiol, LH, FSH, androstenedione, SHBG, testosterone and leptin were determined. Free androgen index (FAI) and insulin resistance index (HOMA) calculated. In comparison with pre- OB, post – OB had higher values of waist circumferences (P<0.02), while post NW showed no difference. Total and LDL cholesterol were higher in post-NW women, where in obese subjects they were already elevated in the premenopausal periods. Serum leptin levels were higher in post OB than in pre OB, where as they were similar in normal weight women. The risk of leptin levels may be related to the greater abdominal fat deposition. In addition, menopausal status of uncomplicated obese women is associated with a greater abdominal fat deposition and with higher values of free androgen index, which may be considered as factors of cardiovascular risk. Wildman, et al, (2004) conducted a study on appropriate body mass index and waist circumference cutoffs for categorization of overweight and central adiposity among Chinese adults. A nationally representative, cross sectional sample of 15239 Chinese adults aged 35-74 year was studied. Mean blood pressure, total cholesterol, LDL cholesterol, triacylglycerols, and glucose values were incrementally higher and mean HDL cholesterol values were incrementally lower with each unit increase in BMI and waist 38 circumference in both men and women. Lower cutoffs for BMI and waist circumference are needed in the identification of Chinese patients at high risk of cardiovascular disease. Bandini, et al, (2004) observed the relation of body mass index and body fatness to energy expenditure, longitudinal changes from preadolescence through adolescence. A study was conducted to test the hypothesis that reduced EE in the premenarcheal period in girls constitutes a risk factor for an increase in relative weight and percentage of body fat during adolescence. EE was measured at study entry in 196 premenarcheal nonobese girls from Massachusetts, USA Resting metabolic rate (RMR) was measured by indirect calorimeters. Total energy expenditure (TEE) was measured by the doubly labeled water method. Activity energy expenditure (AEE) was calculated from RMR and TEE. After the baseline study girls were followed annually until 4 years after menarche. At each visit height, weight and % BF by bioelectrical impedance were measured. Girls also completed annual food frequency and activity questionnaires. No significant relation in change in % BF with RMR, AEE, or TEE was found. A small positive relation between BMI and score and AEE and TEE, but no significant relation with RMR was found. It is suggested that EE in the premenarcheal period is not a risk factor for increases in % BF or BMI Z score in girls during adolescence. Ardern, et al., (2004) carried out a study on the development of health related waist circumference thresholds within BMI categories. The sample included adults classified as normal weight (BMI= 18.5-24.9), overweight (BMI= 25-29.9), obese I (BMI = 30-34.9) and Obese II (BMI 35) from the third U.S. national health and nutrition examination survey (n=6286). The optimal WC thresholds increased across BMI categories from 87 to 124 cm in men and from 79 to 115 cm in women. The validation study indicated improved sensitivity and specificity with the BMI specific WC thresholds compared with the single thresholds. Compared with the recommended WC thresholds, the BMI specific values improved the identification of health risk. In normal weight, overweight, obese I, and Obese II patients, WC cut offs of 90, 100, 110 and 125 cm in men and 80, 90, 39 105 and 115 cm in women respectively, can be used to identify those at increased risk. Nandurker, et al, (2004), observed the relationship between body mass index, diet, exercise and grastro–oesphageal reflux symptoms in a community. Community subjects (n= 211, mean age = 36 years, 43% males) completed validated questionnaires on gastro-esophageal reflux, energy expenditure, dietary intake and measures of personality and life event stress. Diet, exercise, BMI and other potential risk factors for reflux were analyzed using logistic regression analyses. The overall mean BMI was 26.6,79(37%) reported infrequent reflux and 16 (8%) reported frequent reflux. The median calorie intake was 2097 cal/ day. Among those with BMI >25, 10% reported frequent reflux compared to 4% of those with BMI<25. In models which included diet and exercise variables, BMI but not diet or exercise was associated with reflux. BMI may be associated with symptomatic gastro- esophageal reflux independent of diet and exercise. Cole, et al, (2005) conducted a study to know what is the best measure of adiposity change in growing children: BMI, BMI% BMI Z-score or BMI Centile. A study was conducted to identify the optimal BMI measure for change, whose short term variability was most consistent for children across the spectrum of adiposity. A total of 135 children from a kindergarten in Italy, aged 29-68 months at baseline, with BMI measured 3 times over a 9 month period. Each child’s short term variability in adiposity was summarized by the standard deviation (S.D.) of BMI and BMI % adjusted for age and BMI Z- Score. The within child S.D.S. of BMIZ-score and BMI Centile were significantly smaller in obese than non obese children, while the S.D.S. of BMI and BMI % were similar in the 2 groups. Also, the within Childs S.D.S. of Z score and centimes’ and to a lesser extent BMI % were significantly inversely correlated with baseline Z-score where as the S.D. of BMI was not. The changes in adiposity over time, as assessed by the 4 measures, were very highly correlated with each other, particularly for BMI with BMI %. Better alternatives are BMI itself or BMI %. The results underscore the importance of using a relatively stable method to assess adiposity change when following children at risk of obesity. 40 Hynkyung and Deurenberg, (2005) conducted a study on Body mass index ad body fat percent of Koreans in Seoul and Pusan compared to those of Caucasians. The relationships between percent body fat (% BF) and body mass index (BMI) in Koreans was determined. In addition, % BF and BMI were compared with those of Caucasians. Complete data were collected from 3297 subjects (2441 females and 856 males aged 18-79 years) between September and November 2001 in Seoul and Pusan, Korean Republic. For statistical analysis, only data from subjects aged 18-65 years (n=3200) were used. Body weight and height were measured, BMI (Kg/m 2) was computed and % BF was calculated using age and sex specific prediction formulas. % BF was assessed using an INBODY 2.0 body fat analyzer. Data analysis showed that females were significantly younger, smaller, and lighter and had a lower BMI than male’s % BF was higher in females than males. The differences between actual and predicted % BF were correlated with body fat level and age. There was a significant age related decrease in body fat in Koreans for any given BMI and sex, which was remarkably different, compared to age related increases in body fat in Caucasians. 2.2 PHYSICAL ACTIVITY AND OBESITY: Hills and Byrne, (2004) carried out study on physical activity in the management of obesity physical activity is any movement of skeletal muscles that results in energy expenditure. Long term success in weight management depends on both physical activity and dietary modification. Exercise has a pivotal role in weight management, optimizing body composition by minimizing fat free mass losses and maximizing fat mass loss and enhancing metabolic fitness. The amount and the type of exercise needed to obtain health related benefits may differ from that recommended for fitness benefits. Public health messages about exercise have focused on improvements in general health and fitness rather than on weight loss, prevention of weight gain or weight regain. About 2.5 times more exercise than the US surgeon general’s recommendation is needed to maintain energy balance and thus maintain a certain weight. The challenge is to get the exercise prescription right at an individual level. 41 Janssen, et al, (2004) conducted a study on overweight and obesity in Canadian adolescents and their associations with dietary habits and physical activity patterns. Nationally representatives sample of 11-16 year old adolescents (n=5890) from the Canadian components of the 2001/2002 world health organization. Health behaviors in school aged children survey were used. Height, weight, dietary habits, and leisure time activities were determined from self report. Age and gender specific prevalence rate of overweight and obesity were calculated based on international body mass index cut points. Logistic regression was employed to examine the association among measures of overweight, obesity and lifestyle habits. Fifteen percent of 11-16 year old Canadian youth were overweight (preobese) and 4.6% were obese in 2002. These prevalence rates were greater in boys than girls, but did not vary according to age. There were no clear associations observed between dietary habits and measures of overweight and obesity. However, physical activity levels were lower and television viewing times were higher in overweight and obese boys and girls than normal weight youth. Dansou, et al, (2004) studied the effects of physical activity on adipose tissue cellularity in pre-menopausal obese women in Benin. This study investigated the effect of exercise on the adipocyte level of 6 obese women from Benia, who underwent physical training 3 times a week for 6 months. Another 6 obese women who didn’t undergo physical training were included as controls. Biopsy samples of adipose tissue were taken from the gluteal iliac region at baseline and after 6 months and analyzed by histochemistry and electron microscopy. All subjects had severe central obesity. Lipid content and adipocyte level were higher among the sedentary groups than the exercise groups intense exercise used more lipids than carbohydrates it is concluded that a regular, supervised exercise programme reduces lipid levels, thus inducing weight loss. Treuth, et al, (2004) carried a longitudinal study of fitness and activity in girls predisposed to obesity. Normal weight girls (N=91) were recruited at 8 year of age according to parental body mass index. LN = girls 42 with two lean parents. LNOB= girls with the obese and one lean parents and OB = girls with two obese parents. A longitudinal study was undertaken with annuals assessment at 8,9 and 10 year at age. The primary outcomes were fitness measured by treadmill testing and physical activity measured by heart rate monitoring and by questionnaire. The percent of the day spent active on the weekday and weekend didn’t change over time or between groups. Time spent on watching TV during the school year and summer was similar over the study period and between groups. The fitness and physical activity remain fairly constant in girls from 8 to 10 years of age, but girls of obese parents tend to be less fit. Fulkerson, et al, (2004) assessed weight bearing physical activity barriers, benefits, self efficiency, social influence and behaviors among girls and their mothers according to girls weight status, participants were 9 to 11 years old girls and their mothers who participated in the baseline assessment of a nutrition and PA intervention trial. Girls and mothers WBPA attitudes and mothers WBPA behaviors were self reported on questionnaire. Overweight status was based on BMI, compared with non-overweight girls. Overweight girls were significantly more likely to report barriers to WBPA participation and perceive social influence from family and friends to do more WBPA. They were also significantly less likely to report self efficacy regarding WBPA and to believe that they did enough WBPA compared with mothers of non overweight girls. Mothers of overweight girls were significantly more likely to report that it is difficult to persuade their daughters to do more WBPA and significantly less likely to report that WBPA was fun for their daughters. Kazaks and Stern, (2004) examined how diet, exercise and behavior contribute to obesity, as well as interventions that might be effective to control the epidemic. The genetic determinants and environmental factors associated with overweight and obesity were studied. Distorted food portions, food availability, dietary fat, energy dense foods, and calories in drinks encourage overeating. Reduced energy intake, reduced dietary fat intake, and increased physical activity are key elements in long term weight 43 management. Behavioral therapy and strategies to control obesity such as self monitoring, stimulus control, cognitive restructuring and social support are also studied. Several approaches to weight management are suggested. Kemper, (2004) determined the longitudinal relationship of two lifestyle factors (EE and EI) with body composition. Body composition was measured with height, weight and four skin folds (biceps, triceps subscapularis and supra iliaca). Overweight -ness was estimated from body mass index (BMI) and the sum of four skin folds (S4S). EE and EI were measured by cross check interview from structured questionnaires. The median value of EI/ EE in both sexes varies from 6/1 between age 13 to age 32. BI and S4S increase exponentially. The percentage of subjects that have BMI>25 increases from 2% at age 13 to 25% in females and 45% in males at age 36. A high EE is in males significantly related worth lower S4S and BMI. A high EI was not related to a lower BMI and S4S in both genders. A low physical activity pattern is the key factor in the increasing trends of youngsters of overweightness and obesity. Therefore, promotion of physical activity in adolescence and young adulthood seems to be effective in early prevention of obesity. Das, et al, (2004) observed the energy expenditure in extremely obese women. A cross sectional study was conducted in 30 extremely obese women. TEE was measured over 14d using the doubly labeled water method. Resting energy expenditure and the thermic effect of feeding (TEF) were measured using indirect calorimetry and activity energy expenditure (AEE) was calculated as TEE (REE- TEF). Body composition was determined using a 3-compartment model. Subsets were divided into turtle, of BMI for data analysis. TEE and REE increased with increasing BMI tertile TEE. No significant differences were observed among BMI tertile for AEE, TEF or physical activity level. Extremely obese individuals have higher absolute values for TEE and REE, indicating that excess energy intake contributes to the maintenance of excess weight. Standard equation developed for nonobese populations provided the most accurate estimates of REE for the obese individuals studied here. REE was not accurately predicted by equations developed in obese populations. 44 2.3 OBESITY AND SOCIOECONOMIC STATUS: Zhang and Wang, (2004) together studied the secular trends in the disparity of obesity across socioeconomic status (SES) groups among U.S. adults. National representative data collected in the national health and nutrition examination surveys conducted in 1971 to 1974, 1976 to 1980, 1988 to 1994, and 1999 to 2000 from 28,543 adults of 20 to 60 years old, was used in the study. Obesity was defined based on BMI calculated using measured weight and height. Trends in the relationship between obesity and education levels were analyzed controlling for age, gender and ethnicity. The disparity in obesity across SES has decreased over the past 3 decades. In national health and nutrition examination surveys I (1971 to 1974), there was as much as a 50% relative difference in the obesity prevalence across the three groups, but by 1999 to 2000, it decreased to 14%. This trend was more pronounced in women. This trend of diminishing disparities in obesity was also revealed by logistic and linear regression analysis. In most sociodemographic groups, the relationship between BMI and SES has been weakened over time, when the prevalence of obesity increased dramatically. Individual characteristics are not likely the main cause of the current obesity epidemic in the U.S., where as social environmental plays an important role. Monteiro, et al, (2004) examined the impact of different social, familiar and behavior factors on the risk of developing obesity in adolescents Brazil. A case control study nested in a population based cohort that was followed from birth in 1982. The cases were adolescents with obesity as defined by the world health organization. The control came from randomly chosen samples of members of the cohort examined in 1997 and 1998. Information concerning risk factors was obtained from cohort records that were collected at different ages. Multivariate analysis was carried out using logistic regression. The risk factor varies according to sex. Among boys, a family income at birth above one minimum wage and anxiety were associated with 6 and 4 fold increase in risk of obesity, respectively. In both sexes, a one unit increase in pre-pregnancy maternal body mass index was associated with a 10% increase in risk of obesity. Smoking, fat consumption 45 time spent in watching television or performing physical activity and concurrent maternal weight were not associated with obesity. Klumbiene, et al, (2004) analyzed the pattern of socio-demographic variations in the prevalence of obesity in Estonia, Finland and Lithuania. In addition the association between obesity and selected health behaviors was examined. Cross sectional surveys were conducted among representative national samples of adult population in 1994, 1996 and 1998. The number of participants aged 20-64 was 8759 in Estonia, 9488 in Finland and 5635 in Lithuania. The data were obtained from mailed questionnaire covering socio demographic characteristics, health behavior indicators and self reported height and weight. Obesity was defined as BMI>= 30 kg/m 2. The prevalence of obesity among men and women was 10% and 15% in Estonia, 11% and 10% in Finland and 10% and 18% in Lithuania, respectively. Obesity was more prevalent among those aged over 50 in all three countries. It was also more prevalent among the less educated women in all countries and among the less educated men and Finland. Obesity was less prevalent among daily smokers among Estonian men and women and Lithuanian men. Physically inactive Estonian women and Finnish men and women were more likely to be obese. A significant association is found between low educational levels and obesity in women in all the countries, but this association is found in Finnish men only. Thus, even through the social gradient of obesity is broadly similar in all the countries studied; differences emerge with regard to the behavioral correlates of obesity. Musaiger, et al, (2004) investigated the social factors associated with body shape preferences for females and males as perceived by Arab women living in Qatar and correlated the current weight status of women studied with these preferences. The subjects were 535 non pregnant. Arab Women aged 20-67 years who attend health centers in Doha city, the capital of the state of Qatar. Illustrations of males and female body shapes ranging from very thin to very obese using the 9 figure silhouettes scale were shown to women and they were asked to select their preferred figure. Body mass index (BMI) was used to determine the weight status of women studied. Age, educational level and employment status were found to be significantly 46 associated with ideal body shape preference for both males and females, where as marital status and current weight status had no significant association. In general, the Arab women studied selected a more mid range of body fitness for males than for females. It is concluded that attention should be given to socio-cultural factors, such as body shape preferences, in any programme to promote ideal weight for the public. Sutjahjo, et al, (2004) carried out a study on perceived personal, social and environmental barriers to weight maintenance among young women. In Oct- Dec 2001 a total of 445 women aged 18-32 years, selected randomly from the Australian electoral roll, completed a mailed self report survey that included questions on 11 barriers to physical activity and 11 barriers to healthy eating relating to personal, social and environmental factors. Height, weight and socio demographic details were also obtained. Statistical analyses were conducted mid 2003. The most common perceived barriers to physical activity and healthy eating encountered by young women were related to motivation, time and cost. Women with children were particularly likely to report a lack of social support as an important barrier to healthy eating. Perceived barriers didn’t differ by SES or overweight status. Health promotion strategies aimed at preventing weight gain should take into account the specific perceived barriers to physical activity and healthy eating faced by women in this age groups, particularly lack of motivation, lack of time and cost. Strategies targeting perceived lack of time and lack of social support are particularly required for young women with children. Veiga, et al, (2004) assessed the changes in body mass index (BMI) among Brazilian adolescent. In 1975, 1989 and 1997, a household survey of the weight and statures of a probabilistic sample of about 50,000 Brazilian adolescents aged 10-19 years were taken. Weighted prevalence was calculated and an analysis was performed with the sample design taken into account. Adolescents of rich (South-east) and poor (north-east) regions showed a substantial increase in BMI. In the southeast, prevalence of overweight defined by international age and gender specific BMI cutoffs for both genders reached 17% in 1997, where as in the northeast the prevalence 47 tripled, reaching 5% among boy’s and 12% among girls. Older girls living in urban areas in the southeast showed a decrease in the prevalence from 16% to 13% in the latter 2 surveys. For all boys and for young girls, the BMI values for the 85th percentile in 1997 were much higher than the 95th percentile values in 1975. BMI increased dramatically in Brazilian adolescents, mainly among boys, among older girls from the richest region, the prevalence of overweight is decreasing. Danielzik, et al, (2004) identified the major risk factors of overweight and obesity like parental overweight, socio economic status and higher birth weight in pre-pubertal children. A total of 2631, 5-7 years old children and their parents are taken for the study. Main outcome measures are weight status, socio economic status, parental overweight, dietary intake, activity, inactivity and further determinants of the children. The prevalence of overweight was 9.2% in boys and 11.2% in girls, respectively. Family, environment and development related determinants showed some relation to overweight and obesity. In multivariate analysis parental overweight, a low SES as well as a high birth weight were the strongest independent risk factors of overweight and obesity in children. Additionally, there were sex specific risk factors. Parental smoking and single households were risk factors in boys; where as a low activity was associated with obesity in girls. Overweight families of low SES have the highest risk of overweight and obese children. Further prevention programme must also take into account sex specific risk factors. 2.4 OBESITY AND DISEASES: Douketis & Sharma, (2004) conducted a study on the management of hypertension in the overweight and obese patient. The management of hypertension in the overweight and obese patient is a frequently encountered but under investigated clinical problem. The conventional management of such patients involves weight reduction with dietary therapy or a combined approach with dietary and anti-obesity drug therapy. However, long term weight reduction, which is necessary to sustain blood 48 pressure (BP) control, is not feasible in over 80% of patients. Anti-obesity therapy with sibutramine may be associated with a modest worsening of BP control. Consequently, antihypertensive drug therapy is often required to supplement a weight reduction programme and also in patience with severe hypertension or hypertension associated end-organ damage. Concurrent disease is an important determinant of first line and supplementary antihypertensive drug therapy. Additional studies are needed to determine the long term efficacy and safety of anti-hypertensive and anti obesity management strategies in the overweight and obese hypertensive patients. Pischon, et al, (2004) reviews studies on the effects of weight loss on hypertension, dyslipidaemia, diabetes and impaired glucose tolerance. Dietary interventions as well as pharmacological treatment with orlistat and sibutramine are considered. It is concluded that slight reduction with non pharmacological methods and treatment with orlistat and sibutramine confer improvements in biochemical and physiological markers of cardiovascular risk. Hamilton, et al, (2004) studied on obesity and associated complications. The relationship between obesity and mortality is affected by several factors including age, ethnicity, body composition, body fat distribution, stature and fitness. The morbidities related to obesity are cardiovascular complications, congestive heart failure, ventricular ectopic, venous stasis, ulcers, venous thrombosis, pulmonary embolism, sleep apnea, gastrointestinal disorders, osteoarthritis, neurological consequences, and dermatological disorders. Some disorders unrelated to physical effects of adiposity include gall bladder disease, neoplasm, menstrual irregularity, infertility, polycystic ovary syndrome and skin problems. Additional obesity related complications affecting quality of life, emotional well being and self image as well as the economic casts of obesity are also discussed. Ogawa, et al, (2004) studied the prevalence of obesity and its association with the development of diabetes, macro-angioplasty and microangioplasty. The clinical records of 634 patients in a hospital with type 2 diabetes were surveyed. The relationship between obesity and diabetic retinopathy and nephropathy and macro-angioplasty was examined using 49 univariate and multivariate analysis. A body mass index (BMI) 25 kg/m2 was used as the diagnostic criterion for obesity. The prevalence of obesity at the time of survey was 35% and a history of obesity was reported in 70% of the survey population. The prevalence of nephropathy in previously obese patients was significantly higher than in non obese patients. The maximum BMI was significantly associated with the development of retinopathy and nephropathy, as shown by logistic regression analysis. This suggests that a history of obesity may be an important risk factor for the development of micro and macro angioplasty in Japanese with type 2 diabetes. Bramlage, et al, (2004) assessed the prevalence of hypertension and the diagnosis, treatment status and control rates of hypertension, in obese patients as compared to patient with normal weight. A cross sectional point prevalence study of 45125 unselected consecutive primary care attences was conducted in a representative nation wide sample of 1912 primary care physicians in Germany. Blood pressure levels were consistently higher in obese patients. Over-all prevalence of hypertension in normal weight patients was 34.3%, in overweight participants 60.6%, in grade I obesity 72.9%, in grade II obesity 77.1% and in grade III obesity 74.1%. The odds ratio (OR) for good BP control in diagnosed and treated patients was 0.8, in overweight patients, 0.6 in grade I 0.5 in grade II and 0.7 in grade III obese patients. The increasing prevalence of hypertension in obese patients and the low control rates in overweight and obese patients document the challenge that hypertension control in obese patients imposes on the primary care physician. Spruch, et al., (2004) analyzed the additional atherosclerosis risk factors in children and adolescents with simple obesity. The study included 106 children with simple obesity. The age of the studied children was 8-16 years. The evaluation of nutrition and diagnosis of obesity were performed on the basis of anthropometrical measurements. In all of the children, body weight, height, thickness of skin folds, circumference of the hips and waist were taken. Also BMI as well as WHR were evaluated with relation to age standards included in the tables and Centile grids. The concentration of triglycerides, total cholesterol and HDL cholesterol were assayed in the 50 blood serum. The level of LDL cholesterol and VLDL cholesterol was determined with an indirect method. The increased total cholesterol level in blood serum was noticed in 68% children with simple obesity. The increased level of atherogenic fraction (LDL cholesterol) was observed in 74.5% obese children and reduced level of protective fraction in 63.2% children. Obesity in both parents was confirmed in 9.5% families of the examined children. In 46% of the family obesity was confirmed in one of the parents. The results indicate that atherosclerosis prophylactics should be realized from the very early childhood. Erem, et al, (2004) estimated the prevalence of overweight and obesity in the Trabzon region and its associations with demographic factors, socioeconomic factors, family history of selected medical conditions, lifestyle factors and hypertension in the adult population. A total of 5016 subjects were included in the study. Individuals more than 20 years were selected from their family health cards. Systolic and diastolic pressure levels were measured for all subjects. Study procedures were carried out in the local health care centers in each town over an 8 month period. The prevalence of obesity was 23.5%; 29.4% in women and 16.5% in men. The combined prevalence of both overweight and obesity was 60.3%. The prevalence of abdominal obesity was 29.4%, 38.9% among women and 18.1% among men. The prevalence of obesity increased with age, being highest in the 60-69 year old age groups, but lower again in the 70+ age groups. Obesity was associated positively with marital status, parity, cessation of cigarette smoking, alcohol consumption and household’s income and inversely with level of education, cigarette use and physical activity. Busetto, et al, (2004)conducted by a study on the short term effects of weight loss on the cardiovascular risk factors such as blood pressure blood glucose, total cholesterol ,high density Lipo-protein, (HDL) cholesterol and triglycerides were determined before and 15.32.1 months after laparoscopic gastric banding in 650 morbidly obese patients. Global cardiovascular risk was calculated according to the prospective cardiovascular Munster (PROCAM) scoring system. Mean weight loss was 22.720.4 Kg. Normalization of the metallic alteration was observed in 51 67.3% of patients with diabetes, 38.3% of patients with hypercholesterolemia, 72.5% of patients with low HDL-cholesterol, 72.3% patients with hypertriglyceridemia and 46.7% of patients with hypertension. Percentage of weight loss was significantly related to the reductions of fasting blood glucose, triglyceride level and the PROCARM score and to the increase of HDL cholesterol concentrations observed after surgery. However the strength of these four relationships was generally low. Weight loss observed in the first 12 to 18 months after gastric banding was associated with a significant improvement of single cardiovascular risk factors and global risk. On the other hand, the extent of weight loss was poorly related to the magnitude of improvement in cardiovascular risk. Ribeiro et al, (2004) analyzed the body fatness and clustering of cardiovascular disease risk factors in Portuguese children and adolescent. The cluster of CVD risk factor was determined in 1533 children, 731 males and 802 females. Sex and age specific high risk quartiles were formed for each of the biological risk factors and the life style factor. Thus for blood pressure, cholesterol, and obesity, the sex and age adjusted 4 th quartile was defined as the ‘high risk’ quartile, while for physical activity the 1 st quartile (1) was defined as the high risk quartile. The majority of the children at risk of obesity are at risk of other risk factors. 8-15 years old children in the highest quartile of body fitness are an increased risk of having a cluster of other risk factors, namely HBP, HTC and LPAI. These data provide further evidence that juvenile obesity warrants early intervention because of the patterns of unhealthy behavior are formed in adolescence and young adulthood. Vorona, et al, (2005) examined the association between restricted sleep and obesity in a heterogeneous adult primary care population. A total of 1001 patients from 4 primary care practices in Virginia, USA participated in this prospective study. The relationship between body mass index (BMI) and reported total sleep time per 24 hours was analyzed after categorizing patients according to their BMI as being of normal weight (<25), overweight (25-29.9), obese (30-39.9) or extremely obese (40). Analyzable forms from 924 patients aged 18-19 years indicated that the mean BMI was 30, women 52 slept more than men, overweight and obese patients slept less than patients with a normal BMI and this trend of decreasing sleep time was reversed in the extremely obese patients. This study found that reduced amounts of sleep are associated with overweight and obesity. Interventions manipulating total sleep time could elucidate a cause and effect relationship between insufficient sleep and obesity. Parsi (2004) conducted a study on obesity and cardiovascular diseases. 5459, patients were examined, in 2002, 37.3% of whom were overweight or obese. The ratio of male: female was 44:56%. The main symptoms for their consultation at the cardiologists were dyspnoea during exercise, thoracic pain, and decrease in physical exercise capacity, day time fatigue, and peripheral edema. These patients had arterial hypertension (31.42%), cardiac failure (47.30%) angina pectoris (12.10%) and other complaints (10.18%). There is a clear relationship between obesity and cardiovascular diseases. Because of high costs for morbidity due to obesity in hospital and outpatients care, attention should be focused on the reduction of obesity. Zepter, et al, (2004) studied on the mechanism of obesity- related hypertension. Obesity has become an epidemic problem in western societies, contributing to metabolic disease, hypertension and cardiovascular diseases. Although the importance of obesity as a cause of hypertension is well established, the molecular basis of the relationship between obesity and increased blood pressure remains poorly understood. This brief review examines the association between obesity and hypertension along with the mechanisms and proposed to explain this association, while presenting evidence of a direct causal effect of adipose tissue in the development of hypertension through the involvement of the adrenal cortex. Tingfan, et al, (2004) assessed the relation between obesity and asthmatic airway inflammation. Asthmatic patients aged 7-18 year old were recruited. Weight-for-height Z score was calculated from anthropometry. Exhaled nitric oxide (ENO) was measured by online single breath method using a chemiluminescence analyzer; where as leukotriene B4 (LTB4) concentration in exhaled breath condensate (EBC) were quantified using 53 competitive enzyme immunoassay. Ninety two asthmatics and 23 controls were recruited. The mean ENO and LTB4 concentrations in EBC were higher in asthmatic patients than controls. Obesity as defined by weight >120% median weight for height was not associated with any alteration in ENO or LTB4 concentrations in patients with Asthma. ENO and LTB4 concentrations in EBC are increased in childhood asthma. However, these inflammatory markers didn’t differ between obese and non obese children with asthma. Loon, et al (2004) conducted a study on intromycellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly endurance athletes. Immunofluorescence microscopy was performed on muscle biopsies obtained from eight high trained endurance athletes, eight type 2 diabetes patients and eight overweight sedentary men after an overnight fast. Mixed muscle lipid content was substantially greater in the endurance athletes. More than 40% of the greater mixed muscle lipid content was attributed to a higher proportion type I muscle fibers. The remaining difference was explained by a significantly greater IMCL content in the type I muscle fibers of the trained athletes. Differences in the IMCL content between groups or fiber types were accounted for by differences in lipid droplet density, not lipid droplet size. In conclusion, IMCL contents can be substantially greater in trained endurance athletes compared with overweight or type 2 diabetes patients. Because structural characteristics and intramyocellular distribution of lipids aggregates seems to be similar between groups, we conclude that elevated IMCL deposits are unlikely to be directly responsible for inducing insulin resistance. Wannamethee, et al, (2004) conducted study to examine the prevalence of disease burden and disability associated with overweight and obesity in men aged 60-79 years and assessed whether the current WHO weight guidelines are appropriate in the elderly. In total 4232 men aged 6079 year with measured weight and height were taken for the study. Cardiovascular risk factors, prevalence of diabetes, cardiovascular disease, cancer, disability, were observed in the subjects. In total 17% of the men were obese and a further 52% were overweight. Prevalence of hypertension, low HDL cholesterol, higher triacylglycerols, and insulin resistance and the 54 prevalence of most disease outcomes increased with increasing degrees of overweight and obesity. Men in the normal weight range (18.5-24.5 kg/m2) had the lowest prevalence of ill health. Compared with normal weight men, obese men showed a 2 fold risk of major CVD and locomotors disability and were nearly 3 times as likely to have diabetes, CV interventions or to be on CV medication. In elderly men, overweight and obesity are associated with a significantly increased burden of disease, in particular CV related disorders and disability. Consedine, et al, (2004) studied on obesity and awareness of obesity as risk factors for breast cancer in six ethnic groups. A stratified cluster sampling plan was used to recruit 1364 older women from Brooklyn, NY, during 2000-2002. Two groups were born in the United States, where as others were from the English-speaking Caribbean, Haiti the Dominican republic and Eastern Europe. Participants provided demographics, height and weight measures, and estimates of the risk obesity posed for breast cancer. Women from all groups were significantly overweight (BMI>25 kg/m2), although European Americans were lowest, followed by Dominicans and Haitians. Knowledge of obesity as a breast cancer risk factor was also poor across groups, but Dominicans and Haitians, had the loosest scores on knowledge. Importantly, knowledge was not associated with BMI in the overall sample, even when controlling for demographic and ethnicity, although logistic regressions comparing normal weight women with overweight and obese grouping suggested some knowledge of breast cancer risk in the overweight, but not in the obese groups. Cikim, et al, (2004) evaluated the relationship between different types of obesity and cardiovascular risk indictors. A total of 623 overweight and 2559 obese women were divided into four groups according to their BMI and waist to hip ratio. In simple overweight BMI 25-30 kg/ m2 and WHR <0.8, was observed, in abdominal adiposity BMI >30 kg/m2 and WHR >0.8, was recorded, in peripheral obesity BMI >30 kg / m2 and WHR <0.8 and central obesity BMI>30kg m and WHR >0.8 was recorded. The levels of the risk indicators measured were significantly higher in the central obesity groups. Total body fat and abdominal accumulation seems to result in more serious 55 hyper insulinaemia and insulin resistance in central obesity. Measuring BMI and WHR in obese patients may reveal their risk for coronary heart disease. Groot, et al, (2005) investigated the relationship between body mass index (BMI) and nitric oxide in exhaled air (eNo) in Netherlands. Twenty four (10 males and 14 females) healthy non smoking subjects of mean age 27-39 years, mean BMI 23.0 kg/m2, mean eNo level 18.1 ppb were enrolled in this study. The results showed that these lung function parameters of all subjects were normal none of the subjects had airflow obstruction and the mean forced vital capacity was 85.0 %. BMI was positively associated with mean eNo (p=0.007). The findings show a significant increase in eNo level in subjects with higher BMI. The data suggest that direct or indirect up regulation of inflammatory processes outside the adipose tissue and a contribution of obesity related inflammatory activity tot eh pathophysiology of asthma. Rode, et al, (2005) studied the relationship between pre-pregnancy and obstetric body mass index BMI as well as fetal complications in large, unselected cohort of Danish women with single cephalic pregnancies. A cohort of 8092 women from the Copenhagen first trimester study with a registered pre-pregnancy BMI and a single cephalic term delivery were stratified into 3 BMI groups, normal weight (BMI > 25 kg/m2), overweight (BMI 25-29.9 kg/m2) and obese (BMI30 kg/m2). The effects of BMI and parity on the outcome were analyzed using multivariate logistic regression analyses. Overweight women had an odds ratio (OR) of 3.4 for diabetes, 1.9 for hypertension, 1.7 for preeclampsia and 1.5 for cesarean delivery. The corresponding figures for obese women were 15.3 4.8, 2.7 and 1.7 respectively. No relationship was found between BMI and vacuum extraction. Obese women had an increased risk of delivering macroscopic but also low birth weight children. The rate of complications during pregnancy and delivery increases with an increasing pre-pregnancy BMI in women with single cephalic term pregnancies, particularly in nulliparous women. 56 Auer, et al, (2005) studied about obesity, body fat and coronary atherosclerosis, in six hundred and seventy three men and four hundred and twenty eight women who underwent coronary angiography for suspected or known coronary heart disease were analyzed. The body mass index BMI and the BF were used as main exposure variables, and either the presence of significant coronary diameter stenosis or a coronary artery disease severity score were defined as outcome variables, in a sex specific logistic regression analysis. Among male patients, BF was slightly higher with increasing number of vessels involved. In contrast, BMI slowed no association with presence and severity of coronary artery disease (CAD). These results did not differ between younger and older men and females, associated with an increasing number of vessels involved. These results suggested that BF may be predictive of an increasing number of coronary vessels involved among male patients, but not among female patients. This study failed to detect a positive association of presence and severity of CAD with BMI. Rana, et al, (2004) studied obesity and the risk of death after acute myocardial infarction. A prospective cohort study of 1898 patients hospitalized with confirmed acute myocardial infraction was done. The patients were categorized according to WHO criteria for body mass index (BMI). Of the 1898 eligible patients, 607 were normal weight, 832 were overweight, 331 were class I obese and 128 were Class II or more obese. The relative risk of death in all obese patients was 1.46 compared with those with normal weight. BMI appeared to have a positive, graded relation with post myocardial information death. Shah (2009) conducted a study on obesity and sexuality in women as sexual health is an important part of an individual’s overall health. This article presents the definitions and classification of female sexual dysfunction (FSD), emphasizes the importance of obtaining a sexual health assessment, and describes the tools that can be used for this assessment. The impact of obesity on reproductive health over a women’s entire life span is described. The treatment of obesity will have a positive effect on a woman’s sexual health, with a likely improvement in FSD and a decrease in risk factors related to contraception, pregnancy, infertility and menopause. 57 Zavorsky (2009) reviewed the cardiopulmonary aspects of obesity in non-pregnant women. The effects of obesity on pulmonary diffusing capacity and pulmonary gas exchange are related to the waist-to-hip ratio. Obese women have an increased risk for heart failure compared with normal weight women, a risk that progressively worsens with increasing body mass index. They also have poor cardiac accommodation and possess a lower oxygen pulse at peak exercise. Cardiac output, heart rate and total blood volume are higher in obese women whereas ejection fraction is lower compared with normal weight women; substantial weight loss normalizes these parameters. Lash and Armstrong (2003) reviewed the impact of obesity on women’s reproductive health and fertility. Obesity is associated with early puberty, aberrant menstrual patterns, decreases contraceptive efficacy, ovulatory disorders, and an increased miscarriage rate and worse assisted reproductive technology outcomes. Losing weight can ameliorate many of these problems. Dennis (2007) reviewed the effects of obesity that have particular relevance for postmenopausal women. The health consequences of obesity include increased risk of heart disease, hypertension, diabetes, sleep apnea, cancer, osteoarthritis and mental health problems. Post-menopausal women have reached an age when the incidence of chronic health conditions becomes more prevalent. In addition to physical disease risks a lifetime of ridicule and disrespect may seriously and adversely affect general and health related quality of life. Thus, obese post-menopausal women stand at a crossroads between living the remainder of their lives in essentially good health and facing the likely on set of chronic diseases that might have been prevented. 2.5 DIET AND OBESITY: Kiefer and Kunze, (2005), studied on changes in dietary behaviour and body weight within the framework of the weight reduction program. Ten 600 minute sessions of professional counseling were performed in 150 clients formed in small groups. Food intake and dietary behavior were determined 58 using a weighing protocol and questionnaire. To determine long term success, a follow up control check was conducted after a minimum of 6 months and a maximum of 24 months, after counseling was stopped. The results showed that body weight was reduced by an average of 3.96 kg over 9 weeks. At one year follow up., 73.2% of clients had a body weight below their initial weight, 37% had a body weight below their end weight and 14.8% had a body weight similar with end weight. During the counseling period, energy intake from foods and drinks was significantly reduced, primarily through reduction in food intake, from 37.8% of total energy intake in week 1 to 34.7% in week 9. There were reductions in cholesterol, sucrose, salt and alcohol intakes. It is concluded that due to the long term success in terms of weight loss and modification of dietary behaviors, the programme is well suited for weight reduction. Layman, (2004), assessed that protein quantity and quality at levels above the RDA improves adult weight loss. Evidence is accumulating that diets with reduced carbohydrates and increased levels of high quality protein are effective for weight loss. These diets appear to provide a metabolic advantage during restricted energy intake that targets increased loss of body fat while reducing loss of lean tissue and stabilizing regulations of blood glucose. It is proposed that the branched chain amino acid leaking is a key to the metabolic advantage of a higher protein diet because of its unequal roles in the regulation of muscle protein synthesis, insulin signaling and glucose recycling via alanine. These metabolic actions of leucine require plasma and intracellular concentration to increase above minimum levels maintained by current dietary guide liens and dietary practices in the USA. The research suggests that increased use of high quality protein at breakfast may be important for the metabolic advantage of a higher protein diet. Schmidhuber and Shetty, (2004), studied on nutrition transition, obesity and non communicable diseases. The last few decades have seen fundamental changes in food intake patterns around the world. The changes are characterized by an increase in the amounts of food consumed and a shift in the composition of the diet towards more meat, eggs, dairy 59 products, and fats and oils. The main drivers for this transition are rapidly falling food prices, urbanization with the development of new marketing changes and freer trade and globalization are also discussed. Policy options on possible remedies to stop the obesity epidemic are examined. Pandher and Jasvinder, (2004), studied on energy and nutrient intake in obese children. The energy and nutrient intake and energy intake to basal metabolic rate (EI: BMR) ratio of 60 students (30 males and 30 females) were determined. The students were from 3 public schools in Ludhiana and were chosen on the basis of their weight for age data, being 20% above normal. The average daily intake of energy for both sexes was higher than the recommended dietary allowance (RDA) with values of 2161.40±351.24 and 2139.38 298.71 Kcal, respectively for males and females. The higher energy intake was due to higher intake of fats, oils, milk and milk products, roots and tubers. Protein, carbohydrate and fat contributions to total energy intake in males and females were 12.6, 52.99 and 34.41% and 12.35, 54.46 and 33.19% respectively. EI: BMR ratio was 1.64 and 1.95 for males and females, respectively. The overall intake for both sexes of ascorbic acid, retinol, thiamine, and folate exceeded the RDA, including calcium, vitamin B12 where as pyridoxine and iron intakes were lower than the RDA. The intake of niacin, riboflavin and vitamin B12 were higher where as pyridoxine and iron intakes were lower than the RDA. The intake of niacin, riboflavin and vitamin B12 were close to the RDA. The high levels of Vit C were due to increased intake of citrus fruits among subjects. Daily iron intake was below the RDA due to the inadequate consumption of green leafy vegetables, whole cereals and pulses. Tentolouris, et al, (2004) studied the effect of two different is energetic meals, one rich in carbohydrates and one rich in fat, on plasma active ghrelin levels in lean or obese subjects. Eight obese and eight lean women, strictly matched for age, were fed two isoenergetic meals of different composition, one rich in fat and one rich in carbohydrates on separate days. Plasma active ghrelin level was measured just before and at 1.2 and 3 hours after meal consumption. Overall plasma active ghrelin level was significantly lower in the obese compared to the lean women. 60 Furthermore, ghrelin levels decreased significantly by 30% from baseline values in the lean subjects in the first hour after the carbohydrate rich meal returning to near baseline levels by 2 hours, while no significant change was observed in obese subjects. After the fat rich meal, active ghrelin levels did not change significantly in either group. A fat rich meal does not suppress plasma active ghrelin levels in either lean or obese women. More-over in obese, unlike lean women, a higher carbohydrate meal also fails to suppress plasma ghrelin levels, which are already quite low. This suggests that ghrelin induced satiety mechanisms may be compromised in these subjects. Hauner, (2004), conducted a study to know whether a low carbohydrate or low fat diet is better for weight low. Several recent clinical studies show that a low carbohydrate diet produces greater initial weight loess than conventional low fat diets, and is associated with a greater reduction of elevated serum triacylglycerols. After one year, however, weight loss is similar with both diets. Since the intake of saturated fat is higher on a low carbohydrate diet, there may be an increased risk of elevated levels of LDL cholesterol, thus furthering atherosclerosis, over the long term. Before, low carbohydrate diets can be considered an equivalent alternative to low fat diets for the treatment of obesity, long term clinical trials are urgently required. The greater weight loss under low carbohydrate diets would appear to be due to a lower calorie intake. Successful weight loss largely depends on restricting the intake of calories, but the supply of essential nutrients should be guaranteed. Hill, (2004), studied to know does dieting make you fat. Dieting makes you fat, the title of a 1980s book on weight control is a popularized paradox, conveying conclusion that is consistent with personal experience and the reported failure of most dietary approaches in the treatment of obesity. Few studies have been designed specifically to test this association. Yet there are prospective data showing that baseline dieting or dietary restraint increased the risk of weight gain, especially in women. Metabolic adaptations and the disinhibited eating of restrained eaters have been the most commonly cited explanations in the development and persistence of binge eating. 61 Lowe and Timko, (2004), studied to know Dieting: really harmful, merely ineffective or actually helpful? Dieting has developed a negative reputation among many researchers and health care professionals. However, “dieting” can refer to a variety of behavioral patterns that are associated with different effects on eating and body weight. The wisdom of dieting depends on what kind of dieting is involved, who is doing it and why. Thus, depending on what one means by the term, dieting can be quite, harmful, merely ineffective or actually beneficial. In particular, we argue that judgments about the desirability of dieting should consider the likely consequences to particular individuals of engaging in or not engaging in dieting behavior. Waller, et al, (2004) tested the hypothesis that providing a structured snack in the form of a ready to eat breakfast cereal would help regulate excess energy intake and contribute to weight loss in night snackers. Adult of age range 18-65 years of age, BMI 25 kg/m2, with self reported night snacking behaviors, were randomized into a cereal groups (CR) and a no cereal groups (MC). During a period of 4 weeks, the cereal groups was instructed to consume a serving of ready to eat cereals with low fat milk 90 minutes after their evening meal. Concurrently, the non cereal groups continued their regular diet. At baseline, there were no significant differences between groups for age, body weight, body mass index, daily calorie intake or evening calorie intake. There was correlation between number of days of compliance with past dinner cereal consumption and weight loss. Compared to baseline, the complaint CR groups reduced their total daily calorie intake by- 396.50641.6 Kcal where as the NC groups experienced a reduction of-23.22889.60 kcal/ day during the same period. Reduction in post dinner calorie intake for the compliant CR groups was significantly greater compared to the NC groups. Eating ready to eat cereal after the evening meal may attenuate calorie intake in night snackers and promote weight loss in compliant individuals. Mori, et al, (2004) examined whether dietary fish enhanced the effects of weight loss in serum leptin levels, in 69 overweight, treated hypertensive men and women. Participants were randomized to a daily fish 62 meal, a weight reduction regimen, the two regimens combined or a control groups for 16 weeks. A total of 63 individuals completed the study. Weight fell 5.6+/ -0.8 kg with energy restriction. Blood pressure (BP) reductions in the combined fish weight loss groups were twice that seen with either intervention alone. At baseline, in all groups combined, serum leptin levels correlated with serum insulin, but not with body weight. The greatest change in serum leptin occurred in the fish weight loss groups. In the fish weight loss groups, the change in serum leptin was predicted by changes in serum insulin, and 24 hours heart rate. Using general linear models, there was a significant fish and weight loss interaction on post intervention serum leptin after adjustment for baseline levels, independent of post intervention insulin. A daily fish meal as part of a weight reducing regimen was more effective than either measure alone at reducing leptin levels. Reduction in leptin may be related to the substantial fall in BP seen with fish weight loss programme. Hensrud, (2004) studied on diet and obesity. The main aim was to reviews the factors that influence energy intake and dietary treatments used to promote weight loss. Increasing portion size, eating away from home and consuming a variety of higher energy dense foods appear to increase energy intake. Hormonal influence on diet continues to be explored. Very low calorie diets and low carbohydrate diets lead to greater initial weight loss, but long term results are no better than more moderate calories restricted diets. A programme using meal replacements appears to lead to weight loss slightly greater than calories restricted diets and offers one option to treat obesity. Dietary patterns low in energy density and glycemic index have potential in treating obesity and should be studied further. Further studies should explore dietary strategies and combination therapies that contribute to weight loss, long term weight maintenance and improved health. Anderson and Moore, (2004) studied on dietary proteins in the regulation of food intake and body weight in humans. This review presents 4 lines of evidence supporting the role of proteins in the regulation of food intake and maintenance of healthy body weight. It is concluded that the 63 protein content of food and perhaps its source, is a strong determinants of short term satiety and of how much food is eaten. Although the role of protein in the regulation of long term food intake and body weight is less clear, the evidence reviewed suggest that further research to define its role is merited. Such research has the potential to lead to new functional foods, food formulations and dietary recommendation for achieving healthy body weight. Blanck, et al, (2004) studied on diet and physical activity behavior among users of prescription weight loss medications. The sample consisted of 135435 non institutionalized adults aged 18 years old and older. The prevalence and odds of prescription weight loss medication use, odds of 10% weight loss, and among current weight loss medication users, the prevalence and odds for diets and physical activity behaviors were determined. 10.2% of obese women and 3.1% of obese men reported using prescription weight loss medications in the past 2 years of users, 28.2% had lost at least 10% of their pretreatment body weight. The odds of losing at least this much weight were higher among women, those who usually consumed 5 fruits and vegetables daily and those who met physical activity recommendations. Among current prescription weight loss medication users, 26.7% reported both eating fewer calories and meeting recommended leisure time physical activity levels. Of those meeting both recommendation, almost half had lost 10% of their pretreatment body weight. Of current users, 9% reported using the medications for weight maintenance. Only 26.7% of prescription weight loss mediation users reported following recommended diet and physical activity behaviors. Further research is needed to assess whether behavioral changes are associated with greater weight loss and maintenance among prescription weight loss medication users. Hauner, (2004) assessed to know whether a low carbohydrate or low fat diet is better for weight loss? Several recent clinical studies show that a low carbohydrate diet produces a greater initial weight loss than conventional low fat diets, and is associated with a greater reduction of elevated serum triacylglycerols. After one year, however, weight loss is 64 similar with both diets. Since the intake of saturated fat is higher on a low carbohydrate diet, there may be an increased risk of elevated levels of LDL cholesterol, thus furthering atherosclerosis, over the long term. Before a low carbohydrate diets can be considered an equivalent alternative to low fat diets for the treatment of obesity, long term clinical trials are urgently required. The greater weight loss under low carbohydrate diets would appear to be due to a lower calorie intake. Successful weight loss largely depends on restricting the intake of calories, but the supply of essential nutrients should be guaranteed. Seshadri, et al, (2004) conducted a study to compare the effects of low carbohydrate diet and a conventional diet on lipoprotein sub-fractions and inflammation in severely obese subjects. The changes in lipoprotein sub-fractions and C- reactive protein levels in 78 severely obese subjects, including 86% with either diabetes or metabolic syndrome, who were randomly to either a low carbohydrate or conventional diet for 6 months, were compared. Subjects on a low carbohydrate diet experienced a greater decrease in large very low density lipoprotein (VLDL) levels but more frequently developed detectable chylomicron. Both diet groups experienced similar decreases in the number of low density lipoprotein particles and increases in large high density lipoprotein concentrations. Over all, Creactive protein levels decreased modestly in both diet groups. However, patients with a high risk baseline level experienced a greater decrease in C – Reactive protein levels on a low carbohydrate diet, independent of weight loss. In this study, there is an overall favourable effect of a low carbohydrate diet on lipoprotein sub-fractions, and on inflammation in high risk subjects. Both diets had similar effects on LDL and HDL sub-fractions. Miyashita, et al, (2004) investigated the effects of low carbohydrate diet on glucose and lipid metabolism, especially on visceral fat accumulation, and comparing that of a high carbohydrate diet. Obese subjects with type 2 diabetes mellitus were randomly assigned to take a low calorie and low carbohydrate diet or a low calorie and high carbohydrate diet, for 4 weeks. Similar decreases in body weight and serum glucose level were observed in both groups. Fasting serum insulin levels were reduced in 65 the low carbohydrate diet groups, compared to high carbohydrate diet groups. Total serum cholesterol and triglyceride levels decreased in both groups, but were not significantly different from each other. High density lipoprotein cholesterol increased in the low carbohydrate diet group, but not in the higher carbohydrate diet groups. There was a large decrease in visceral fat area measured by computed tomography in the low carbohydrate diet groups compared to the high carbohydrate diet groups. The ratio of visceral fat area to subcutaneous fat area did not change in the high carbohydrate diet groups, but it decreased significantly in the low carbohydrate diet groups. Manco, et al, (2004) studied the effects of dietary fatty acids on insulin sensitivity and secretion. Globalization and global market have contributed to increased consumption of high fat, energy-dense diets particularly rich in saturated fatty acids (SFAs). Poly unsaturated fatty acids (PUFAs) regulate fuel partitioning within the cells by inducing their own oxidation through the reduction of lipogenic gene expression and the enhancement of the expression of those genes controlling lipid oxidation and thermogensis. Moreover, PUFAs prevent insulin resistance by increasing membrane fluidity and GLUT4 transport. In contrast, SFAS are stored in non adipocyte cells as triglycerides leading to cellular damage as a sequence of their lipotoxicity. Triglyceride accumulation in skeletal muscle cells derives from increased FA uptake coupled with deficient FA oxidation. The biochemical mechanisms responsible for lower fatty acid oxidation involve reduced Carnitrine Polmitoyl Transferase (CPT) activity, as a likely consequence of increased intracellular concentration of malonyl COA; reduced glycogen syntheses activity and impairment of insulin signaling and glucose transport. Bharati et al, (2007) studied the prevalence and causes of chronic energy deficiency and obesity in Indian women. The study was based on 81,712 women from 26 states and 6 zones, which were grouped according to geographic proximity of the states of India. A multiple linear regression analysis was done to see the relation between nutritional status of women and different socioeconomic factors. The data revealed that the prevalence 66 of CED, overweight, and obesity in India are 31.2%, 9.4% and 2.6% respectively. The incidences of CED and obesity are negatively related. The prevalence of CED is the lowest in Arunachal Pradesh and highest in Orissa. Punjab has the highest prevalence of obesity and Bihar has the lowest. For the zone wise distribution the Northeast Zone has the lowest degree of prevalence of CED and the East zone is at the bottom of the list with the highest degree of malnutrition. 2.6 OBESITY AND PREGNANCY: Andreasen, et al, (2004) reviewed on obesity and pregnancy. Their paper reviews the potential complications associated with obesity and pregnancy. The complications associated with obesity in pregnancy are gestational diabetes mellitus, hypertensive disorders (hypertension, preeclampsia, and eclampsia) and thromboembolic complications. The complications associated with obesity during labor are augmentation, early amniotomy, cephalopelvic disproportion, caesarean section and preoperative morbidity. The complications associated with obesity in neonates are fetal macrosomia, shoulder dystopia, small for gestational age, late fetal death and congenital malformations, especially neural tube defects. The data suggest that obesity is associated with a higher risk of all reviewed complications except small for gestational age. Waller and Dawson, (2004) conducted a study on the relationship between maternal obesity and adverse pregnancy outcomes. This chapter reviews the literature on maternal obesity with adverse pregnancy outcomes. The methodological issues pertinent to the measurement of obesity in epidemiological studies and the effect of obesity on reproductive function. Pregnancy complications and adverse outcomes of pregnancy (late fetal death, small for gestational age infants, preterm birth and birth defects) are also discussed. 2.7 OBESITY AND PSYCHOSOCIAL ASPECTS: Biedert and Margraf, (2004) studied on the psychosocial aspects of obesity. Obesity is generally a lifelong problem with numerous weight 67 related medical complications. The relationship between body weight and risk of developing a significant disease, as well as total mortality and morbidity, has been examined in many epidemiological studies. Such studies provide insight into biological relationship. In addition to negative physical effects, obesity may also have deleterious psychological and social effects on the individuals concerned. It is not obesity as a physical state that creates a psychological burden for many obese individuals, but rather the people or society who create this burden and suffering. Discrimination and prejudice may have adverse effects on the psychological well being of subgroup of obese persons. Fabricatore and Wadden, (2004) studied on psychological aspects of obesity. Obesity is a complex condition associated with a host of medical disorders. A common assumption is that obesity must also be related to psychological and emotional complications. Research on the psychosocial aspects of obesity has grown more sophisticated over the years, from purely theoretical papers to cross-sectional comparisons of people with and without obesity to prospective investigations of the temporal sequence of obesity and mood disturbance. These studies have shown that obesity, by itself, does not appear to be systematically associated with psychopathological outcomes. Certain obese individuals however are at a greater risk of psychiatric disorder, especially depression. The present paper reviews the research findings and presents there clinical implications. Chiefly, treatment provides should not assume that a depressed or other wise disturbed obese persons needs only to loose weight in order to return to psychological health. Significant mood disturbances should be treated equally aggressively, regardless of a patient’s weight status. Ryden, et al, (2004) conducted a study to examine the effects of weight change on personality traits after 2 years in severely obese subjects treated conventionally or surgically. Personality traits were assessed using 7 of 15 scales from the Karolinska scales of personality (KSP): Somatic anxiety, muscular tension, psychasthenia, psychic anxiety, monotony avoidance, impulsiveness and irritability. A total of 1380 surgical candidates, 1241 68 conventionally treated patients and 1135 subjects form the SOS (Swedish obese subjects) reference study representing the general populations of Sweden completed the KSP. Data presented in this study were gathered twice from the patients and once form the reference subjects. Significance tests and effects sizes (ES) were calculated. At baseline, the obese were characterized as more anxiety prone, impulsive, irritable and less monotony avoiding than the reference groups. These were observed more in surgery patients than in conventionally treated patients. At follow-up, it was found that anxiety proneness decreased and monotony avoidance increased with increasing weight loss. The conventionally treated were on average, weight stable and hence only a small decreased was noted regarding somatic anxiety. The surgery groups lost an average of 28 kg and the differences between surgically treated and the reference groups decreased on all scales except impulsiveness, which remained unchanged. The largest improvement was in relation to psychasthenia. 2.8 OBESITY AND HEALTH CONSCIOUSNESS: Vriendt, et al, (2009) investigated the role of socio-demographic and life style determinants on the nutrition knowledge of Belgian women and the association between their knowledge and dietary behavior. A total of 803 women, aged 18-39 years, were included in a cross – sectional study and completed a general and nutrition knowledge questionnaire and a 2 – day food record. Their height and weight were measured under standardized conditions. Linear regression models showed independent significant associations between the following determinants and the women’s nutrition knowledge (in order of importance) educational level, age, kind of occupation, smoking behavior and work status. Inconsistent or no associations were found for body mass index, physical activity, living situation, and whether or not they had children. The investigated determinants accounted for 13-14.5% of variance in total nutrition knowledge. A rise in nutrition knowledge was associated with a significant rise in consumption of vegetable and fruit, but no differences were seen for other dietary indicators. Most important determinants of the women’s 69 nutrition knowledge were educational level, age and their kind of occupation. Women who had better knowledge of nutrition also exhibited better dietary behaviors, thus underlying the importance of nutrition education for improving dietary behavior. Kristal, et al (2007) studied on nutrition knowledge, attitudes and perceived norms as correlates of selecting low fat diets. Participants were 97 women, aged 45-59, with a broad range of dietary fat intakes. Usual dietary patterns were assessed with a food frequency questionnaire, 8 days of food diaries and an 18- item questionnaire on fat–related diet behavior. Participants completed a questionnaire with 125 items. A Q-sort and item and factor analyses were used to develop their knowledge, two attitude and four norms scales. These scales had fair internal consistency reliabilities (ranges were 0.53 – 0.73) and most were significantly associated with both percent of energy from fat and fat- related diet behavior. Factors most strongly associated with low-fat diets were related to perceived norms and knowledge about fat in foods. In multiple regression models, norms and knowledge contributed significantly and independently to both measures of diet behavior, while the variance explained by attitudes was small. These findings support the inclusion of components that enhance practical food knowledge and change dietary behavior norms in nutrition education programs. These scales may also be useful tools, both to evaluate nutrition intervention programs and to develop hypotheses about dietary behavior which can be tested empirically. Charlton, et al (2004) identified the major sources and credibility of nutrition information among black urban South African women, with a focus on messages related to obesity. Three hundred and ninety-four black women aged 17-49 years were conveniently sampled from the Western Cape and Gauteng provinces in South Africa. The most frequently encountered source of nutrition information was the media, particularly the radio and TV (73.4% and 72.1% of subjects, respectively, obtained information from this source in the past year) followed by family/friends (64.6%). Despite only 48.5% of subjects having received nutrition information from a health professional, this was the most highly credible information source. A lack of knowledge 70 on certain aspects of nutrition was identified as well as misconceptions regarding diet and obesity. To improve the nutrition knowledge and the effectiveness of nutrition education activities in South Africa, it is recommended that health and nutrition educators become more actively involved with the training of health professionals, particularly those engaged in delivery of services at primary care level and in turn encourage health professionals to engage more with media sources. Kearney, et al, (2003) studied on attitudes toward and beliefs about nutrition and health among a random sample of adults in the republic of Ireland and Northern Ireland, by using a self administered questionnaire. A randomly selected sample of 1256 adults from the republic of Ireland and Northern Ireland completed the attitudinal questionnaire. A majority of subjects (62%) perceived that they make conscious efforts to eat a healthy diet either most of the time or quite often, while just over half (52%) agreed that they do not need to make changes to their diet as it is healthy enough. Subjects most likely to make conscious efforts to try to eat a healthy diet were females, older subjects (51-64 yrs) and those with the highest intakes of fruit and vegetable and lowest quartile of fat (% food energy). The results suggest that people appear to be reasonably accurate at evaluating their own diet in terms of how healthy it is. In terms of the two food groups examined in this study, some optimistic bias was evident for vegetables but not for fruit. It may be useful therefore to assess attitudes and beliefs about healthy eating by way by examining attitudes to such food groups individually. Susan, et al, (2000) compared relative weight, weight loss efforts and nutrient intakes among similarly health conscious vegetarian, post vegetarian and non vegetarian premenopausal women. Demographic data, life style practices and weight loss efforts (by questionnaire), body mass index (BMI; Kg/m2) and dietary intake (via multiple-pass 24-hour diet recall) were compared in a convenience sample of 90 current vegetarians, 35 post vegetarians and 68 non-vegetarians. Age (31.9 + 18.8), educational attainment, smoking status, alcohol use, physical activity and perceived health status were similar among the three groups of women. BMI did not 71 differ by dietary pattern and averaged 23.7 + 4.7 for all women combined. Participants had intentionally lost ≥ 10 pounds a mean of 2.1 times and 39% of women perceived themselves to be overweight; again, no differences were observed among dietary groups. Dietary intake of vegetarians and current non-vegetarians were consistent with current recommendations for macronutrient composition (<30% fat, <10% saturates). Compared to current non vegetarians, current vegetarians had lower intakes of protein, saturated fat, cholesterol, niacin, vitamin- B12 and D and higher fiber and magnesium intakes. Vegetarians mean vitamin B12 and D intakes were well below recommendations. Hankey, et al, (2003) studied about the eating habits, beliefs, attitudes and knowledge among health professionals regarding the links between obesity, nutrition and health. A systematic stratified sample of 2290 subjects incorporated general practitioners (n= 1400), practice nurse (n=613) and all practicing dieticians (n=360) who were all member of the British Dietetic Association. The overall response rate was 65%. All professionals showed a clear understanding of nutrition and health. But understanding of obesity as a disease and of the effectiveness of weight management using low energy diets was limited. Below 10% had carried out audit to determine the incidence of obesity and overweight, and most were uncertain about their own effectiveness in delivering weight management advice. This study confirms that health professional have some knowledge of nutrition and weight management but are unclear how to deliver effective weight management advice. Further training is justified to ensure the effective provision of nutritional advice to patients. 72