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UNIT 4: DNA, Chromosomes, and Cell Division DAYSHEET 48: Meiosis and Sexual Reproduction Name _____________________________________ Biology I Date: __________ Catalyst/Bellringer: Use your reading strategies as you read the article below about cancer. Then answer the questions at the bottom. Purpose: To find out what causes cancer Activate Prior Knowledge: What do you already know about cancer? CANCER Cancer is a family of diseases that are caused by genetic mutations, or mistakes in DNA. Mutations can be caused by many things, including exposure to UV rays or contact with certain chemicals (like those found in cigarettes). Mutations can also occur by random chance when the DNA is replicating. Usually mistakes are caught by the cell, but if they’re not the cell could become cancerous. The mutations that cause cancer all have one thing in common – they make the cell and grow and divide uncontrollably. In cancer cells, mitosis happens at a very fast rate. If one cell grows and divides uncontrollably, it can form a mass of cells called a tumor. The tumor can suck nutrients and oxygen away from nearby cells in the body, causing healthy cells to die. NORMAL CELLS CANCER CELLS Many tumors are benign (not dangerous). The tumor can be removed and the person can continue to live a healthy life. But sometimes the cells in a tumor can begin to spread to other parts of the body. When cancer cells spread, the cancer is said to be malignant. If this happens, the person may need to get surgery, chemotherapy, or radiation treatment to try to kill the cancer cells. 1. What is a mutation? __________________________________________________________ 2. What are some things that can cause mutations? ____________________________________ 3. What type of mutation causes cancer? ____________________________________________ 4. What is a tumor? ____________________________________________________________ 5. What does it mean when a tumor is malignant? ____________________________________ Activity 1: Cornell Notes Biology Objective / Essential Question: Main Ideas / Questions: 1. What are the differences between sexual and asexual reproduction? Notes: Characteristic Asexual Reproduction Sexual Reproduction Bacteria – Binary Fission Example Yeast - Budding # of Parents Offspring Where does the DNA come from? Advantages Disadvantages Asexual Reproduction: ______________________________________ _________________________________________________________ Sexual Reproduction: _______________________________________ _________________________________________________________ 2. What cells are involved in sexual reproduction? How are they made? The sperm and egg are called ________________ and only have _________ as much DNA has the other cells in our body. We say these cells are ________________, and use the symbol _____ when talking about these cells. These cells are made by a process called ______________. During this process, DNA from different chromosomes gets mixed up in a process called __________________________________________. This creates new combinations of genes and results in offspring that are genetically unique. Activity 1 Continued: Cornell Notes Main Ideas / Questions: Notes: 3. What about the other cells in our body? The rest of our body cells (such as our skin cells, hair cells, brain cells, cheek cells, etc.) are called ________________ cells. These cells have _________________ the DNA, so we say they are ________________, and use the symbol ______ when talking about these cells. 4. What are the steps of sexual reproduction? Summary 1N 2N Steps to Calculating Chromosome Number HAMMER out the question Use your 1N and 2N columns to figure out what you have and what you are trying to find Use the following rules to calculate chromosome number: 1N 2N MULTIPLY BY 2 2N 1N DIVIDE BY 2 Teacher Example: 1. A human skin cell has 46 chromosomes. How many chromosomes will be in a human egg cell 2. An egg cell of a cockroach has 5 chromosomes. How many chromosomes will be in the fertilized zygote? Your Turn: 3. A squirrel tail cell has 50 chromosomes. How many chromosomes are present an unfertilized squirrel egg cell? Activity 2: Time to Practice! SOMATIC CELLS vs. GAMETES Determine if the cells below are SOMATIC (BODY) CELLS or GAMETES. If the cell is a SOMATIC CELL, write an S in the blank. If the cell is a GAMETE, write a G in the blank. EXAMPLE: __S_ Eye cell 1. ____Cheek cell 2. ____Heart cell 3. ____Sperm cell 4. ____Skin cell 5. ____Nerve cell 6. ____Muscle cell 7. ____Egg cell 8. ____Lung cell 9. ____Liver cell 10. ____Hair cell 11. ____Stomach cell 12. ____Kidney cell DIPLOID vs. HAPLOID Determine if the cells below are HAPLOID or DIPLOID. If the cell is HAPLOID, write an H in the blank. If the cell is DIPLOID, write a D in the blank. EXAMPLE: __D_ Eye cell 1. ____Cheek cell 2. ____Heart cell 3. ____Sperm cell 4. ____Skin cell 5. ____Zygote 6. ____Muscle cell 7. ____Egg cell 8. ____Lung cell 9. ____Liver cell 10. ____Hair cell 11. ____Gametes 12. ____Kidney cell SENTENCE COMPLETION Circle the answer that best completes the sentences below. 1. Human skin cells are (HAPLOID / DIPLOID) Human skin cells contain (23 / 46) chromosomes Human skin cells are (SOMATIC / GAMETE) cells 2. Human egg and sperm cells are ( HAPLOID / DIPLOID) Human egg and sperm cells contain (23 / 46) chromosomes Human egg and sperm cells are (SOMATIC / GAMETE) cells 3. After the sperm fertilizes the egg, the resulting zygote has (23 / 46) chromosomes. CALCULATING CHROMOSOME NUMBER Use the steps listed below to solve the following problems HAMMER out the question Use your 1N and 2N columns to figure out what you have and what you are trying to find Use the following rules to calculate chromosome number: 1N 2N MULTIPLY BY 2 2N 1N DIVIDE BY 2 1. A mosquito zygote contains 12 chromosomes. How many chromosomes are in a mosquito sperm cell? A. 0 B. 6 C. 12 D. 23 2. If a somatic cell in a snake contains 24 chromosomes, how many chromosomes would be in the snake sperm cell? A. 3 B. 6 C. 12 D. 24 E. 4 3. If a gamete in the common garden pea plant contains 7 chromosomes, how many chromosomes would a garden pea plant’s leaf cell contain? A. 0 B. 7 C. 14 D. 28 4. An orangutan zygote contains 48 chromosomes. How many chromosomes does an orangutan zygote receive from the mother’s egg? A. 0 B. 23 C. 46 D. 92 5. If the sperm cells of a fish contain 12 chromosomes, how many chromosomes would be found in the diploid cells of that fish? A. 3 B. 6 C. 12 D. 24 6. If an organism has a diploid number of 28, how many chromosomes would be found in one of its unfertilized egg cells? A. 7 B. 14 C. 28 D. 56 7. After a mouse egg cell containing 30 chromosomes is fertilized, how many chromosomes will be in the zygote? A. 0 B. 15 C. 45 D. 60 8. Horses have 64 chromosomes in each hair cell. How many chromosomes should be in each horse gamete? A. 16 B. 32 C. 64 D. 96 9. The bromeliad flower has 100 chromosomes in each haploid pollen cell. How many chromosomes will be a bromeliad root cell? A. 25 B. 50 C. 100 D. 200 10. The species Ursus maritimus has 70 chromosomes in each somatic cell. How many chromosomes do Ursus maritimus receive from their father? A. 15 B. 35 C. 70 D. 140 INTERPRETING DATA TABLE 6-1 Chromosome Number of Various Organisms Organism 2N Number of Chromosomes Penicillium 4 Saccharomyces (yeast) 18 Mosquito 6 Housefly 12 Garden Pea 14 Corn 20 Fern 1,262 Frog 26 Human 46 Orangutan 48 Dog 78 Use Table 6-1 to answer the questions below. Assume that the chromosome numbers in the table for each organism is 2n. 1. How many chromosomes would a DOG’S skin cell contain?____________________ How many chromosomes would a male DOG’S sperm cell contain?_____________ 2. How many chromosomes would a FROG’S tongue cell contain?________________ How many chromosomes would a female FROG’S egg cell contain?_____________ 3. How many chromosomes would a MOSQUITO wing cell contain?________________ How many chromosomes would a male MOSQUITO sperm cell contain?_________ 4. Which organism has the MOST chromosomes? _____________________________ 5. Which organism has the LEAST chromosomes? _____________________________ 6. Do you think organism complexity is related to chromosome number? Why or why not? Activity 3: Modeling Crossing Over When sperm and egg are produced by the process of meiosis, new genetic combinations are created through a process called crossing over. In crossing over, pairs of chromosomes get together and exchange genes - pieces of DNA – creating new genetic combinations that never existed before! This is the reason why even siblings with the same two parents usually look very different! Directions: In order to create a model of crossing over follow the steps below: 1. Ask your teacher for a chromosome cut-out paper 2. Cut out the original chromosomes and paste them in the box labeled “Origin Chromosomes” 3. Cut out the crossing over chromosomes 4. Cut off a piece of the white chromosome, and a piece of the black chromosome and switch them! 5. Glue your new chromosome combinations in the box labeled “Crossed Over Chromosomes” ORIGINAL CHROMOSOMES CROSSED OVER CHROMOSOMES HW48: Meiosis and Sexual Reproduction Biology I Name: _______________________________ Date: ____________________________ Below are the chromosome numbers for some common organisms. Fill in the blanks on the chart and then answer the questions. ORGANISM SOMATIC CELL (2n) GAMETE (n) Human 46 23 Garden Pea 14 Fruit Fly 4 Tomato 24 Dog 78 Chimpanzee Leopard frog Corn 24 26 10 1. What is the diploid number of chromosome in corn? ______________ 2. What is the haploid number of chromosome in corn? ______________ 3. What is number of chromosome in tomato somatic cell? ______________ 4. What is the number of chromosome in a leopard frog gamete? ______________ 5. Which cells in the human contain only 23 chromosomes? ______________ 6. What is the number of chromosomes in a human zygote? ______________ Calculating Chromosome Number: 1. Each giraffe somatic cell contains 20 chromosomes. How many chromosomes does a giraffe sperm cell contain? (A) 0 (B) 10 (C) 20 (D) 40 2. An elephant egg cell contains 15 chromosomes. How many chromosomes are found in the fertilized elephant zygote? (A) 0 (B) 7.5 (C) 15 (D) 30