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Joint Department of Mathematics and Microbial Sciences Research Theme Mathematical Modelling in Microbiology Wednesday 4th December 2013 Bennett Link Lecture Theatre 2:00pm – 5:30pm 14:00- 14:05 Welcome Marco Oggioni (Genetics, Leicester) 14:05 – 14:25 Dov Stekel (Integrative Systems Biology, Nottingham) “The dynamic balance of import and export on zinc homeostasis in Escherichia coli” 14:25 – 14:45 Christopher Bayliss (Genetics, Leicester) & Michael Tretyakov (Mathematics, Nottingham) “Phase Variation” 14:45 – 15:05 Miguel Cámara (Biomolecular Sciences, Nottingham) “Computer modelling of quorum sensing systems” 15:05 – 15:25 Tom Walsh (Genetics, Leicester) “Some genomics problems in yeast” 15:25 – 15:45 Refreshments (Ground Floor Foyer) The day will explore the panorama of existing interactions that exist locally between the 2 research fields of Mathematical Modelling and Microbiology. It will also offer you the chance to share your knowledge and make new contacts. 15:45 – 16:05 Alexander Gorban (Mathematics, Leicester) A. Zinovyev (Inst. Curie, Paris) E. Smirnova (Siberian Federal University, Russia) “Three small studies in mining biological data: 1) Cluster structures in bacterial genomes;n2) Two straight lines in bacterial genome statistics; 3) Adaptation and disadaptation of populations: measurement of ecological stress.” 16:05 – 16:25 Marco Oggioni (Genetics, Leicester) & Alessandro Boianelli (Engineering, Siena) “A non-linear deterministic model for regulation of diauxic lag on cellobiose by the pneumococcal multidomain transcriptional regulator CelR” 16:25 – 16:45 Andrey Morozov (Mathematics, Leicester) (i) Predation on infected host promotes pathogens' biodiversity (ii) Patterns of patchy spread in multi-species reaction-diffusion population models 16:45 – 17:30 Ideas and Discussion • Chris Turkington: “Influence on phage of phase variable restriction enzymes” • Chiara Mocenni: “Within host evolution in invasive infection” • Hasan Yesilkaya: “A systems approach to galactose metabolism” • Martha Clokie: “Bacteria – phage interactions” ALL WELCOME