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Campus: Princeton High School Author(s): Jody Gerber and Rachella Fannin, Melinda Brooks Date Created / Revised: August 1, 2014; November 23, 2015, December 14, 2016 Six Weeks Period: 4th Grade Level & Course: Biology Timeline: 17 days Unit Title: Unit 8.2: Genetics and Heredity Stated Objectives: TEK # and SE Lesson # 2 B (6) Science concepts. The student knows the mechanisms of genetics, including the role of nucleic acids and the principles of Mendelian Genetics. The student is expected to: (A) identify components of DNA, and describe how information for specifying the traits of an organism is carried in the DNA; (E) identify and illustrate changes in DNA and evaluate the significance of these changes; (F) predict possible outcomes of various genetic combinations such as monohybrid crosses, dihybrid crosses and non-Mendelian inheritance; B (3) Scientific processes. The student uses critical thinking, scientific reasoning, and problem solving to make informed decisions within and outside the classroom. The student is expected to: 3F Research and describe the history of biology and contributions of scientists See Instructional Focus Document (IFD) for TEK Specificity Key Understandings Traits are passed from parent(s) to offspring in a predictable pattern. Misconceptions Some students use the terms gene and allele interchangeably. Some students may think that Punnett Squares determine fixed ratios and that results in the Punnett Squares as “people” rather than probabilities of offspring having a given genotype. The everyday meaning of the term dominance is strength and power in a contest with a weaker opponent (recessive). As a result, these students may have some or all of these common misconceptions: o Dominant alleles are more likely to be inherited than recessive alleles. o Dominant alleles are more likely to be adaptive than recessive alleles. o Recessive alleles are deleterious. o Mutations are recessive. o Dominant alleles regulate the expression of recessive alleles. o Dominant alleles are found at greater frequency than recessive alleles in populations. Students may think that every trait is represented by gene and that each gene has 2 and only 2 alleles. Key Vocabulary See vocabulary words for each day. Understanding vocabulary is imperative for students if they are going to pass STAAR. Use these words repeatedly. Suggested Day 5E Model Instructional Procedures (Engage, Explore, Explain, Extend/Elaborate, Evaluate) Materials, Resources, Notes, and Vocabulary Words Day 1 Wed Jan 11 Objective: Students will learn the basics of history and genetic theories Topic: Basic History of Genetics and Genetic Theory Engage Engage – Find a genetic video that would interest students - www.trypearsontexas.com - Untamed Science from Levine and Miller Explain – Use PPT and notes to explain the history of genetics o Common thoughts of Mendel’s day o Focus on Gregor Mendel o Genetic Theory 3 Modern Principles Day 2 Thurs Jan 12 Explain Elaborate Closing: Students will give an example of the 3 modern principles of genetics: Law of Dominance and Recessive, Law of Independent Assortment, Law of Segregation Objective: Students will learn genetic vocabulary Topic: Genetic Vocabulary Needed to Predict and Solve Genetic Problems Explain – Explain vocabulary words that students must know to predict and solve genetic problems. - Use plastic cups to explain vocabulary words and determine if students comprehend basic vocabulary Elaborate – Cross word puzzle or vocabulary word cards Closing: Students will complete a cross word and a card sort Materials - Copy notes for each student - Set of video for students to watch Resources – pages 308-311. 317 http://www2.edc.org/weblabs/ mendel/mendel.html Notes Vocabulary Words Genetics Heredity Gregor Mendel Factors Genes Purebred Hybrid True-breeding P, F1, and F2 Law of Dominance and Recessive Law of Independent Assortment Law of Segregation Materials - Copy notes for each student - Please and plastic cups/transparency (1 set for each student) Resources – See vocabulary below. Notes It is imperative that student understand these vocabulary words if they are going to solve genetic problems. Vocabulary Words Allele Genotype Phenotype Dominant Recessive Homozygous Heterozygous Day 3 – Fri Jan 13 Explain Explore Objective: Students will learn about and use Punnett squares to predict the outcome of the offspring Topic: Probability and Punnett Squares Materials - Copy notes for each student - 2 Coins/students (pennies) Explain – PPT and notes probability and Punnett Squares Resources – page 313-315 http://www.youtube.com/ watch?v=Y1PCwxUDTl8 Explore – Lab: Coin Toss Closing: Students discuss probability and where their traits came from Notes Vocabulary Words Probability Punnett Square Day 4 – Tues Jan 17 Engage Explain Explore Objective: Students will learn basic vocabulary and complete a monohybrid cross Topic: Monohybrid Crosses Engage – PTC, Thiourea, and Sodium Benzoate taste paper - Based on class results have students try and predict which is dominant and recessive Explain – Use PPT and notes to explain how to solve monohybrid crosses Materials - Get PTC, Thiourea, and Sodium Benzoate taste paper (1/student) - Copy notes and worksheet for each student Resources – pages 316 http://biology.clc.uc.edu/courses /bio105/geneprob.htm Notes Explore – Monohybrid worksheet Closing: Students will complete a WS over monohybrid crosses. Day 5 – Wed Jan 18 Evaluate Explore Vocabulary Words Monohybrid Genotype Phenotype Probability Punnett Square Gamete Homozygous Heterozygous Objective: Students will apply their knowledge of monohybrid crosses to complete an activity Topic: Monohybrid Crosses (cont.) Materials - Copy Gizmo lab (Mouse Lab) for each student Evaluate – Quiz over monohybrid cross Resources Explore – monohybrid activity Notes - Schedule computer lab in advance - Have students study for a quiz over monohybrid crosses Closing: Students will be able to complete a monohybrid cross Vocabulary Words Monohybrid Genotype Phenotype Probability Punnett Square Gamete Homozygous Heterozygous Day 6 Thurs Jan 19 Objective: Students will learn about dihybrid crosses Topic: Dihybrid Crosses Explain Elaborate Explain – Use PPT and notes to explain dihybrid crosses - Teach FOIL method and/or double monohybrid crosses Materials - Copy notes and worksheet for each student Resources - page 316-318 Day 7 Fri Jan 20 Elaborate – Dihybrid worksheet Notes Closing: Students will complete a dihybrid cross Vocabulary Words Dihybrid Genotype Phenotype Probability Punnett Square Gamete Homozygous Heterozygous Objective: Students will complete an activity over dihybrid crosses Topic: Dihybrid Crosses (cont.) Materials - Copy Gizmo lab for each student Explore – Bikini Bottom Dihybrid crosses Resources - page 316-318 Closing: Students will set up and complete a dihybrid cross Notes - Schedule computer lab in advance - Tell students to study for dihybrid quiz Explore Vocabulary Words Dihybrid Genotype Phenotype Probability Punnett Square Gamete Homozygous Heterozygous Day 8 Mon Jan 23 Evaluate Explain Explore Elaborate Objective: Students will learn there are exceptions to genetics, so students will learn about non-Mendelian genetics Materials Copy notes and worksheet for each student Resources – pages 395 Topic: Non-Mendelian Crosses: : Incomplete Dominance and Codominance Explain – Use PPT and notes to explain incomplete dominance and codominance (compare and contrast) Explore- Incomplete and Co-Dominance Elaborate - incomplete dominance and codominance worksheet Day 9 Tues Jan 24 Topic: Non-Mendelian Crosses: Polygenic and Multiple Alleles, Sex-linked Explain Elaborate Explain – Use PPT and notes to explain sex-linked traits Elaborate – Sex-linked worksheet Notes Vocabulary Words Sex-linked X chromosome Y chromosome Hemophilia Color-blindness Materials Copy notes and worksheet for each student Use hemophilia and color blindness as examples Resources – pages 319, 394 Closing: Students will complete a WS over sex-linked traits Explain – Use PPT and notes to explain polygenic and multiple allele Explore – Computer activity (blood typing) o Nobelprize.org Notes The worksheet is an excellent worksheet for helping students understand incomplete codominance and codominance Vocabulary Words Incomplete Dominance Codominance Day 10 Wed Jan 25 Explain Explore Objective: Students will use a manipulative to understand the rules of genetics Topic: Genetic Traits Materials: Mr Potato Head Explore: Mr Potato Head activity Closing: Students will use determine traits passed on from mom and dad and create a “Mr potato head” child Day 11 Thurs Jan 26 Objective: Students will learn the terminology of a pedigree Topic: Pedigree with computer activity Explain Explore Explain – Use PPT and notes to explain pedigree Explore – Computer Activity Pedigree Or have students complete a pedigree for their own family. Gummy Bear Pedigree Closing: Students will create a gummy bear pedigree from a set of guidelines Materials Copy notes and computer activity for each student Gummy bear Resources – pages 175 - 176 http://www.zerobio.com/drag_gr11/ pedigree/pedigree_overview.htm Notes Schedule computer lab in advance if you want to do this activity Vocabulary Words Pedigree Materials Copy notes and worksheet for each student Resources – pages 319, 486 Notes If you want to do the computer activity you will need to schedule the computer lab Vocabulary Words Polygenic Multiple Alleles Day 12 Fri Jan 27 Objective: Students will explore DNA fingerprinting. Topic: - DNA Fingerprinting Explain Explore http://learn.genetics.utah.edu/content/labs/gel/ Materials Resources – page 433 http://www.pbslearningmedia.org/asset/tdc02_int_createdna fp2/ Notes Schedule computer lab Vocabulary Words Assessment: Genetics Review Closing: the students will complete the computer generation. Day 13 Mon January 30 Accommodations for Special Populations Assessment: Genetics Test Accommodations for instruction will be provided as stated on each student’s (IEP) Individual Education Plan for special education, 504, at risk, and ESL/Bilingual.