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Brochure More information from http://www.researchandmarkets.com/reports/2374451/ Blood Component Preparation: From Benchtop to Bedside Description: This convenient resource has it all—not only the different methods for blood component preparation but also the effects that those methods have on the product itself and, thus, the blood recipient. The book addresses four major areas: overview of methods, additive solutions and containers, frequently used modifications, and updates on recent technologies and techniques. Chapters cover: - Component therapy concepts. - The platelet-rich plasma, buffy-coat and apheresis methods. - RBC and platelet additive solutions and containers. - Leukocyte reduction. - Component irradiation. - Components for infants. - Pathogen reduction technologies. - Use of automation. - LEAN manufacturing. This book will be a useful reference for transfusion service physicians and those in the component preparation unit alike. Contents: Preface About the Editors 1 Blood Component Therapy from the Beginning Paul J Schmidt, MD Background Events Blood and Politics Plasma Civilian Blood and Plasma Banks Serum for Transfusion Red Blood Cells Platelets Cryoprecipitate Granulocytes Yesterday and Tomorrow References 2 Preparation of Whole-Blood-Derived Platelet Concentrates Ralph R Vassallo, MD, FACP History and Description of Platelet Components from Whole Blood Whole Blood Collection Variables and Their Effects on PRP-PCs Bacterial Contamination of PRP-PCs Prestorage Pooled PRP-PCs PRP-PCs vs Apheresis PCs and Buffy-Coat PCs Nonplatelet Content of PRP-PCs Conclusion References 3 The Buffy-Coat Method Pieter F van der Meer, PhD, and Dirk de Korte, PhD Blood Bag Systems and Automated Separators Production of BC-Derived Platelet Concentrates BC-Reduced Red Cell Concentrates and Plasma Overnight Hold of Whole Blood Further Automation of Centrifugation and Separation Processes Characteristics of BC-Derived Platelet Concentrates After Production Storage of BC-Derived Platelet Concentrates In-Vivo Evaluation of BC-Derived Platelet Concentrates Seven-Day Platelet Storage Summary References 4 Apheresis Preparation of Blood Components James W Smith, MD, PhD Historical Development of Apheresis Preparation of Blood Components Rationale for Apheresis Component Preparation Technologies Involved in Apheresis Component Preparation Components Prepared by Apheresis Adverse Effects on Donors and Recipients Summary References 5 Containers and Storage Solutions for Red Blood Cells John R Hess, MD, MPH, FACP, FAAAS, and Walter E Kelley, DO Development of Liquid Red Cell Storage Red Cell Metabolism Effects of Storage Solution Ingredients Compositions of Solutions How Storage Solutions Work Plastic Bags Red Cell Rejuvenation Solutions Development of Frozen Red Cell Storage Freeze-Dried Red Cells References 6 Containers and Additive Solutions for Platelets Hans Gulliksson, PhD Historical Background In-Vitro Platelet Aging at 22 C vs In-Vivo Aging at 37 C The Use of PAS in Combination with Different Methods for the Preparation of Platelets for Transfusion In-Vitro Activation of Platelets During Collection, Preparation, and Storage at 22 C Effects on Platelet Metabolism and Function Associated with Chemical Components in PAS The Platelet Storage Container In-Vivo Characteristics of PAS PAS Options and Alternatives References 7 White Blood Cell Reduction of Blood Components Eleftherios C Vamvakas, MD, PhD, MPH Proven Benefits of WBC Reduction Process Control of WBC Reduction Prevention of Transfusion-Related Immunomodulation Prevention of Transmission of Variant CreutzfeldtJakob Disease Other Possible Benefits of WBC Reduction Conclusion References 8 Transfusion-Associated Graft-vs-Host Disease and Component Manufacture Jed B Gorlin, MD, MBA Background Pathophysiology Treatment General Considerations for Irradiation Indications for Irradiation Alternatives to Irradiation References 9 Blood Components for Infants Ronald G Strauss, MD Red Blood Cell Transfusions Platelet Transfusions Plasma Transfusions Cryoprecipitated AHF Transfusions References 10 Pathogen-Inactivation Technologies for Blood Components Miguel Lozano, MD, PhD Technologies for Plasma Technologies for Platelets Technologies for Red Blood Cells Summary References 11 Automation in Blood Component Preparation Methods Joan Cid, MD, PhD First-Generation Automation Second-Generation Automation Third-Generation Automation The Future of Automation for Blood Component Preparation Methods Conclusion References 12 Six Sigma and Lean Concepts in the Component Laboratory Bobbi Keefe, MT(ASCP), and Michelle Stefan What Is Lean? What Is Six Sigma? Six Sigma and Lean Synergy Project Teams and Project Management Lean Six Sigma Tools Case Study 1: Carter BloodCare’s Component Processing Laboratory Case Study 2: Implementation of Automation in a Component Laboratory Keys to Success References Index Ordering: Order Online - http://www.researchandmarkets.com/reports/2374451/ Order by Fax - using the form below Order by Post - print the order form below and send to Research and Markets, Guinness Centre, Taylors Lane, Dublin 8, Ireland. Page 1 of 2 Fax Order Form To place an order via fax simply print this form, fill in the information below and fax the completed form to 646-607-1907 (from USA) or +353-1-481-1716 (from Rest of World). If you have any questions please visit http://www.researchandmarkets.com/contact/ Order Information Please verify that the product information is correct. 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