Download QIANG LIU, M.D.

CURRICULUM VITAE
QIANG LIU, M.D.
MEDICAL LICENSE:
New York State, Medical and Surgery, License #: 235782
Illinois State, Physician and Surgeon, License #: 036 –116201
New Jersey State, Physician, License #: 25MA08243400
BOARD CERTIFICATION:
Anatomic Pathology and Clinical Pathology, 2005
EDUCATION AND DEGREES:
1978 - 1983
1984 - 1988
M.D.
M.Sc.
Henan Medical University, Henan, China
Beijing Medical University, Beijing, China
PROFESSIONAL EXPERIENCE:
July, 2007 – present
Assistant professor, Department of Pathology, Einstein College of Medicine, New York
• Surgical and GI/liver pathology
July, 2006 – June, 2007
Fellow of GI/liver Pathology, Department of Pathology, The University of Chicago
• Clinical training: GI/liver pathology
• Research: Gene expression in chronic ulcerative colitis.
July, 2005 – June, 2006
Fellow in Surgical Pathology, Department of Pathology, New York University School of
Medicine
• Clinical training: Surgical pathology
July, 2001 – June, 2005
Resident, Department of Pathology, New York University School of Medicine
• Clinical training: Anatomic and clinical pathology
• Research: The role of oncogenes and tumor suppressor genes in tumorigenesis of
pancreas
1. Establishing BOP-induced hamster pancreatic cancer model and determining its
suitability for molecular alterations, imaging and gene therapy
2. Generating mouse model systems using the most frequent oncogene present in
human pancreatic cancer, K-ras
3. Generating mouse model systems with inactivation of the tumor suppressor genes
involved in human pancreatic cancer (p16, p53, and DPC4/SMAD4)
July, 1999 – June, 2001
Research Fellow, Surgical Research Lab at San Francisco General Hospital, University of
California at San Francisco
Curriculum Vitae of Qiang Liu, page 2
• Study of cystic fibrosis transmembrane regulator (CFTR) gene mutations and
pancreatitis
February 1994 – June, 1999
Research Fellow, Department of General Surgery, Rush-Presbyterian- St. Luke's Medical
Center
• Study of the effects of cigarette smoking on the hamster pancreas as a possible model
for pancreatic cancer
• Study of the effects of IL-6, GCSF, and glutamine-enriched formula in the septic
complications of acute pancreatitis in dogs
• Study of the effects of bombesin, transforming growth factor-ß, epidermal growth factor
and lexipafant (BB882) on bacterial translocation in rat pancreatitis
• Tumor angiogenesis of gastrointestinal neuroendocrine tumors, pheochromocytomas,
and thyroid carcinomas
July, 1988 – January, 1994
Attending Surgeon, Department of General Surgery, The First Teaching Hospital of Beijing
Medical University, China
• Clinical practice: Practiced General Surgery specializing in pancreatic and liver
diseases.
• Research: Study of “analysis of K-ras gene mutations in patients with pancreatic
adenocarcinoma”
• Taught General Surgery to fifth year medical students for two semesters.
July, 1984 – June, 1988
Resident and Postgraduate Student, Department of General Surgery, The First Teaching
Hospital of Beijing Medical University, China
• Clinical training: Rotated for three years in surgical specialties including orthopedics,
urology, general and thoracic surgery. Spent three months in anesthesiology and
surgical intensive care units and nine months in the emergency room.
• Research: Study of pancreatic exocrine function in patients with acute hemorrhagic
necrotizing pancreatitis. Title of thesis: "The Long-Term Observation and Pancreatic
Exocrine Function Study in Patients with Acute Hemorrhagic Necrotizing Pancreatitis"
August, 1983 – June, 1984
Intern/Resident, Department of Surgery, Zhumadian Medical School, China
• Clinical training and teaching
HONORS AND AWARDS:
1. Stowell-Orbison Awards, Certificates of Merit. The 96th Annual Meeting of the United
States and Canadian Academy of Pathology. March 24-30, 2007 San Diego, CA
“Immunohistochemical Expression of Vitamin D Receptor Correlates with Decreased
Immunohistochemical Activity of Peroxisome Proliferator-Activated Receptor-a in
Steatohepatitis”
2. Research grant, Rush University Committee on Research. “The Effect of Lexipafant on
the Septic Complications of Acute Pancreatitis,” July 1997.
Curriculum Vitae of Qiang Liu, page 3
3. National Contest for Research Article of Excellence, Chinese Association of Surgery.
“Analysis of Pancreatic Juice in Patients with Acute Hemorrhagic Necrotizing Pancreatitis
by Endoscopic Retrograde Pancreatic Drainage,” May, 1993.
4. Research grant, Chinese Ministry of Health. “Analysis of K-ras Gene Mutations in
Patients with Pancreatic Adenocarcinoma,” January 1992.
MEMBERSHIPS:
American Pancreatic Association, 1996 to 1999
United States and Canadian Academy of Pathology, 2001 to present
American Society for Clinical Pathology, 2004 to present
RESEARCH TECHNIQUES:
1. Animal Surgery:
Animal models of pancreatitis in dogs, mice, and rats
Animal models of pancreatic cancer in hamsters
Animal model of portal hypertension in dogs and rats
2. Molecular Biology:
Isolation of DNA and RNA
Gel electrophoresis (agarose, polyacrylamide)
Southern hybridization, PCR, SSCP, DNA sequencing, RT-PCR
3. Tissue Processing and Immunohistochemistry
Paraffin and frozen section preparation and Immunohistochemical staining of factor
VIII, P53, and Pancreatitis associate protein
Cryopreservation of parathyroid tissue
4. Immunology:
ELISA: tumor necrotic factor assay
Western blot analysis of pancreatitis associate protein
5. Cell cultures:
Pancreatic acinar cell line
Primary cultures of pancreatic acinar cells and hepatocytes
6. Microbiology:
Gram positive, Gram negative and anaerobic bacterial cultures
PEER REVIEWED ARTICLES AND BOOK CHAPTER:
1. Tsuang W, Subramanian R, Liu Q. The need for liver biopsy in a patient with acute HCV infection.
Nat Clin Pract Gastroenterol Hepatol. 2008;5:54-7.
2. Liu Q, Tobias H, Petrovic LM. Drug-Induced Hepatitis Associated with Ezetimibe Therapy. Dig Dis
Sci 2007;52:602-5.
3. Liu Q, Hajdu C, Petrovic LM. Pseudopapillary Solid Tumor of Pancreas. Gastroenterology
2007,132:1224, 1638.
Curriculum Vitae of Qiang Liu, page 4
4. Liu Q, Bannan M, Melamed J, Witkin GB, Nonaka D. Two cases of hepatoid adenocarcinoma of the
intestine in association with inflammatory bowel disease. Histopathology. 2007;51:123–5.
5. Chen D, Kaplan L and Liu Q. Evaluation of Two Chemiluminescent Immunoassays of ADVIA
Centaur for Hepatitis B Serology Markers. Clin Chim Acta. 2005 May;355:41-5.
6. Kim T, Liu Q, Gattuso P, and Prinz RA. Histopathologic Changes Induced by Cellophane Wrapping
of the Pancreas are Unaffected by Cigarette Smoke Exposure in Hamsters. Pancreatology 2002;2:45662.
7. Kouris GJ, Liu Q, Gattuso P, and Prinz RA. The Effect of Glucagon-like Peptide 2 on Intestinal
Permeability and Bacterial Translocation in Acute Necrotizing Pancreatitis. Am J Surg. 2001
Jun;181:571-5
8. Liu Q, and Harris HW. Increased Susceptibility of Pancreatic Acinar Cells to Hyperstimulatory
Stress in Delta F508 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Heterozygous
Mice. Gastroenterology 2000; 118:A1041
9. Liu Q, Gattuso P, and Prinz RA. The Effect of Interleukin-6 on Bacterial Translocation in Acute
Canine Pancreatitis. International J Pancreatology 2000;27:157-165
10. Liu Q, Gattuso P, and Prinz RA. The Effect of Lexipafant on Bacterial Translocation in Acute
Necrotizing Pancreatitis in Rats . Am Surg 1999;65:611-617
11. Liu Q, Gattuso P, and Prinz RA. Total Thyroidectomy for Benign Thyroid Disease. Surgery
1998;123:2-7
12. Liu Q and Prinz RA. Pancreatitis Associated with Hyperlipidemia and Hyperparathyroidism. In:
Howard JM, Idezuki Y, Ihse I, Prinz RA eds. Surgical Diseases of the Pancreas 3rd ed. Baltimore:
Williams & Wilkins, 1998:271
13. Liu Q, Gattuso P, and Prinz RA. The Effect of Epidermal Growth Factor on the Septic
Complications of Acute Pancreatitis. J Surg Res 1997;69:171-177
14. Liu Q, Gattuso P, and Prinz RA. Tumor Angiogenesis in Pheochromocytomas and
Paragangliomas. Surgery 1996;120:938-943
15. Liu Q, Gattuso P, and Prinz RA. The Effect of Transforming Growth Factor-ß on Bacterial
Translocation of Acute Pancreatitis in Rats. Pancreas 1996;13:448
16. Liu Q, Gattuso P, and Prinz RA. Simultaneous Fine-Needle Aspiration and Core-Needle Biopsy of
Thyroid Nodules. Am Surg 1995;61:628-633
17. Liu Q, Gattuso P, and Prinz RA. The Effect of Bombesin on Bacterial Translocation of Acute
Pancreatitis in Rats (Abstract). Pancreas 1995;11:439
18. Huang YT, Yang YM, Liu Q. Point Mutation of K-ras Gene in Pancreatic Carcinoma. Chinese
Med J 1994;74:77-79,125-126
19. Yang YM, Huang YT, Liu Q. Ras Genes and Pancreatic Neoplasms. Chinese Med J 1994;74:386388
20. Liu Q , Zhang BS, Huang YT. Long-Term Results of Surgical Treatment for Acute Hemorrhagic
Necrotizing Pancreatitis. Chinese Med J (English) 1993;106: 500-503
21. Liu Q, Zhang BS, Huang YT. Analysis of Pancreatic Juice in Patients with Acute Hemorrhagic
Necrotizing Pancreatitis. Chinese Med J 1993;
Curriculum Vitae of Qiang Liu, page 5
22. Liu Q, Zhang BS, Huang YT. Acute Hemorrhagic Necrotic Pancreatitis: Clinical Pathology and
Long-Term Results of Surgical Treatment. Chinese J Surg 1991;29:104-106
23. Mao CY, Liu Q et al. Diagnosis and Treatment of Severe Pancreatitis. Chinese J Surg
1990;28:24-27
24. Mao CY, Liu Q et al. A Retrospective Study on Diagnosis and Treatment of Severe Acute
Pancreatitis. Chinese Med J (English) 1990;103:546-51
25. Huang YT, Liu Q et al. Short Term Observation of Portal Pressure After Portosystemic Shunt.
Chinese J Surg 1986;24:711-714
ABSTRACTS AND MEETING PRESENTATIONS:
1. Liu Q, Tanaka KE, Whitney KM and Hart J. Two toned hepatocytes: A striking histologic change
likely due to a drug effect. 98th Annual Meeting of USCAP., Boston, Massachusetts, March 7-13, 2009.
2. Liu Q, Campbell LK, and Hart J. Immunohistochemical Expression of Vitamin D Receptor Correlates
with Decreased Immunohistochemical Activity of Peroxisome Proliferator-Activated Receptor-α in
Steatohepatitis. 96th Annual Meeting of USCAP. San Diego, CA, March 24-30, 2007.
3. Liu Q, Hart J and Noffsinger A. Reduced Immunoexpression of O6- Methylguanine-DNA
Methyltransferase (MGMT) in Inflammatory Bowel Disease (IBD)- Associated and Sporadic Serrated
Polyps. 96th Annual Meeting of USCAP. San Diego, CA, March 24-30, 2007.
4. Liu Q, Tao Z, Bannan M, Melamed J. Appendiceal Diverticulitis: A Greater Susceptibility to
Perforation of the Appendix. Am J Clin Pathol 2006;126:658
5. Liu Q, Chiriboga L, Yee H, Zeremski M, Talal AH, Petrovic LM. Increased Expression of
CXCR3 in Acute Allograft Rejection Following Liver Transplantation. Am J Clin Pathol
2006;126:657
6. Liu Q, Yee H, Chiriboga L, West B. Composite Gastric Carcinoma –Carcinoids: Analysis of
Histolopathology and Immunohistochemical Features. Modern Pathology supplement 3, 2006;19:6465
7. Liu Q, and Melamed J. Enhancement of Imprint Cytology with Immunohistochemistry and Fine
Needle Aspiration in Intraoperative Evaluation of Sentinel Nodes for Metastatic Malignant Melanoma.
Modern Pathology supplement 2006;19:321A
8. Liu Q, West B, and Pellicer A. The Effect of Sindbis Viral Vectors on the N-Nitroso-bis(2oxopropyl)amine (BOP) Induced Hamster Pancreatic Ductal Adenocarcinoma and
Cholangiocarcinoma. Modern Pathology supplement 2005; 18: 283A-284A
9. Liu Q, and Liu C. The Clinical Significance of Small Monoclonal B Cell Population Detected by Flow
Cytometry in Patients with Negative Morphologic Findings on Bone Marrow Biopsy. Modern Pathology
supplement 2005;18:240A
10. Liu Q, Gattuso P, and Prinz RA. Angiogenesis as a Prognostic Indicator in GI Neuroendocrine
Tumors. International Surgical Week. Lisbon, Portugal. August 28, 1995