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Schizophrenia Therapeutics: A Market Briefing
Description:
Schizophrenia is a life long affliction. There is no permanent cure for this illness. However, numerous drugs
have made the effective management of the disease a reality.
This briefing examines both corrent and emerging therapeutic approaches for the management of
schizophrenia. It provides an analysis of the current and future markets for these agents, including forecasts
to 2009 segmented by geographic region and by type of drug and likely market scenarios for new agents not
yet available. The briefing discusses the drugs currently in clinical trials, provides epidemiological
information, and profiles the major competitors.
The information presented in this report is the result of primary and secondary research. Secondary
research included data gathered from company product literature and other corporate brochures and
documents, as well as information found in the scientific and trade press. Primary research consisted of
interviews and correspondance with company executives, clinicians, researchers and public health officials.
The market forecasts are based on epidemiology, historical growth rates, probable product introductions,
analyst expectations, and expert consensus.
Contents:
CHAPTER ONE: EXECUTIVE SUMMARY
Epidemiology
Management of Schizophrenia
Drugs in Development
Market Summary
World Market for Novel Antipsychotics
Scope and Methodology
CHAPTER TWO: INTRODUCTION
Schizophrenia
Symptoms
Economic Burden
Causes
Complications
Distorted Perceptions of Reality
Hallucinations and Illusions
Delusions
Incidence
Types
CHAPTER THREE: TREATMENT OPTIONS
Pharmacological Treatments
Relapse Management
Adherence
Non-Pharmacological Treatments
Psychosocial Treatments
CHAPTER FOUR: DRUGS IN CLINICAL TRIALS
Newer Treatment Approaches
Preclinical Agents
A320436
Dopamine D2 Partial Agonist Agent
ORG 25543
MEM 3454
Clera 120
Phase I Clinical Agents
LY 483518
SB 277011
MGS 0028
Muscarinic M1 Agonist Compound
SGS 518
Neboglamine
Phase II Clinical Agents
DAR 0100
Palindore
Reminertant
Lurasidone
Talnetant
Phase III Clinical Agents
Bifeprunox
Lonasen
Iloperidone
CHAPTER FIVE: MARKET FORECASTS
Opportunities and Drivers
World Market Breakdown
5H2 and D2 Antagonist Antipsychotic Agents
Atypical Antipsychotic Agents
5H1A and D2 Partial Agonist and D2 and D3 Antagonist Agents
Novel Antipsychotic Agents
Geographical Breakdown of Antipsychotic Agents
CHAPTER SIX: KEY PLAYERS
Astra Zeneca PLC
Abbott Laboratories
Johnson and Johnson
Novartis AG
Pfizer Inc.
LIST OF EXHIBITS
Exhibit 1: Schizophrenia Cases, Geographical Breakdown
Exhibit 2: Status of Key Late-Stage Antipsychotic Agents
Exhibit 3: World Market for Antipsychotics Summary 2004-2009
Exhibit 4: World Market for Antipsychotics by Geographic Segment Summary 2004-2009
Exhibit 5: World Market for Antipsychotics by Drug Type Summary 2004-2009
Exhibit 6: World Market for Novel Antipsychotics 2006-2009
Exhibit 7: Schizophrenia Cases, Geographical Breakdown
Exhibit 8: World Market for Antipsychotic Agents 2004-2009
Exhibit 9: Expected Launch Dates of Late Stage Antipsychotic Agents
Exhibit 10: World Market for Antipsychotics by Drug Type (5 H2 & D2 antagonists, atypical antipsychotics, 5
H1A & D2 partial agonist, D2 & D3 antagonists, and benzamides) 2004-2009
Exhibit 11: World Market for 5H2 and D2 Antagonist Segment
Exhibit 12: World Market for Atypical Antipsychotic Segment
Exhibit 13: World Market for 5H1A and D2 Partial Agonist Segment
Exhibit 14: World Market for D2 and D3 Antagonist Segment
Exhibit 15: World Market for Novel Antipsychotic Therapies 2006-2009
Exhibit 16: World Market for Antipsychotics by Geographic Segment (U.S., Europe, Japan, ROW) 2004-2009
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