Download CONTENTS

CONTENTS
1. Adjusting the Lock and Adjusting the Key in Cyclodextrin
Chemistry: An Introduction ..................................................................
R. Breslow
2. Models for Enzymic Systems: An Introduction....................................
F. H. Westheimer
1
17
3. Studies on the Mechanism of Action and Stereochemical Behavior
of Semisynthetic Model Enzymes .........................................................
E. T. Kaiser, H. L. Levine, T. Otuski, H. E. Fried,
and R.-M. Dupeyre
35
4. Asymmetric Transformation of a-Substituted Carbonyl Compounds
Via Enamine or Iminazoline Formation ...............................................
S. Yoshikawa, H. Matsushita, and S. Shibata
49
5. Model Studies and the Biochemical Function of Coenzymes ............
D. Dolphin
65
6. Carbon Acid Oxidations and Oxygen Activation by Flavins ..............
T. C. Brake
89
7. Flavin Coenzyme Analogs as Probes of Flavoenzyme Reaction
Mechanisms ...........................................................................................
C. Walsh, F Jacobson, and C. C. Ryerson
119
8. Structure-Function Relationship of Vitamin B12 Coenzyme
(Adenosylcobalamin) in the Diol-Dehydrase System .........................
T. Toraya and S. Fukui
139
9. Some Mechanistic Aspects of Coenzyme B12-Dependent
Rearrangements .....................................................................................
J. Halpern
165
10. Vitamin B12 Models with Macrocyclic Ligands ....................................
Y. Murakami
11. Nature of the Iron-Oxygen Bond and Control of Oxygen Affinity
of the Heme by the Structure of the Globin in Hemoglobin ............
M. F. Perutz
12. The Chemical Basis of Variations in Hemoglobin Reactivity .............
T. G. Traylor, A. P. Berzinis, J. B. Cannon, D. H. Campbell,
J. F Geibel, T. Mincey, S. Tsuchiya, and D. K. White
13. Evidence Regarding Mechanisms for Protein Control of Heme
Reactivity..................................................................................................
B. M. Hoffman, J. C. Swartz, M. A. Stanford, and Q. H. Gibson
14. Activation of Dioxygen Using Group VIII Metal Complexes .............
B. R. James
15. Studies of the Mechanism of Oxygen Activation and Transfer
Catalyzed by Cytochrome P-450 ............................................................
J. T. Groves, S. Krishnan, G. E. Avaria, and T. E. Nemo
16. Oxygen Activation: Participation of Metalloenzymes and Related
Metal Complexes ...................................................................................
291
I. Tabushi and N. Koga
17. Oxygen Activation in Oxygenase Systems: Model Approach
Using Iron-Porphyrin ..............................................................................
307
Z. Yoshida, H. Sugimoto, andH. Ogoshi
179
201
219
235
253
277
18. Intermediate Spin States of Iron Porphyrins.......................................... 327
H. Kobayashi, Y. Kaizu, and K. Eguclii
19. The Active Site of Sepioteuthis lessoniana Hemocyanin ..................... 341
A. Nakahara, W. Mori, S. Suzuki, and M. Kimura
20. Chemical Approaches to Nitrogen Fixation.......................................... 351
W. E. Newton
21. A Possible Mimic of the Nitrogenase Reaction ..................................... 379
J. Chart
22. Molybdothiol and Molybdoselenol Complex Catalysts: Acetylene
Reduction and Electron Spin Resonance Characteristics ..................... 393
Y. Sugiura, T. Kikuchi, and H. Tanaka
23. Metal Ion Effects in the Reactions of Phosphosulfate ........................... 409
W. Tagaki and T. Eiki