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Flowcharts for Zika Additonal Questions
Collection Areas WITHOUT Active Transmission of Zika Virus
Additional Question for Zika: In the past 4 weeks, have you been in any of the areas on this list? (Have
donor review list of locations on CDC webpage http://www.cdc.gov/zika/geo/index.html.)
Donor Eligibility: The Zika virus, which is spread by mosquitos, has recently emerged in the Americas.
While most Zika virus infections are asymptomatic or self-limited, infections have been associated with
serious birth defects (i.e. microcephaly) and a neurological condition, Guillain-Barré syndrome. Therefore,
donors who have traveled to areas with active Zika virus transmissions are deferred from donation for 4
weeks after the date of departure from the area.
NOTE: An “area with active transmission” of Zika virus is an area included on the CDC website listing of
areas with local vector-borne (i.e., mosquito-acquired) transmission of Zika virus. For the current listing,
refer to: http://www.cdc.gov/zika/geo/index.html.
(See February 2016 FDA Guidance: Recommendations for Donor Screening, Deferral, and Product
Management to Reduce the Risk of Transfusion-Transmission of Zika Virus.)
Zika Additional
Question
In the past
4 weeks, have you been
in any of the areas on this list?
(Refer to current list on
CDC webpage.)
No
Accept donor
Yes
Determine 4 week deferral
period based on the date of
departure from the area.
Defer donor
Next question
Collection Areas WITH Active Transmission of Zika Virus
Additional Question for Zika #1: In the past 4 weeks, have you had Zika virus infection?
Donor Eligibility: The Zika virus, which is spread by mosquitos, has recently emerged in the Americas.
While most Zika virus infections are asymptomatic or self-limited, infections have been associated with
serious birth defects (i.e. microcephaly) and a neurological condition, Guillain-Barré syndrome. Therefore,
donors who have a history of infection with Zika virus, are deferred for 4 weeks after resolution of
symptoms.
(See February 2016 FDA Guidance: Recommendations for Donor Screening, Deferral, and Product
Management to Reduce the Risk of Transfusion-Transmission of Zika Virus.)
Zika Additional
Question #1
In the past 4 weeks,
have you had Zika virus
infection?
No
Accept donor
?
Yes
Determine 4 week deferral
period based on the date
donor was symptom free.
Defer donor
Next question
Collection Areas WITH Active Transmission of Zika Virus
Additional Question for Zika #2: In the past 4 weeks, have you had 2 or more of the following symptoms:
fever, rash, joint pain, muscle pain, conjunctivitis (red eyes), headache?
Donor Eligibility: Donors who provide a history of having two or more of the listed symptoms, which are
associated with Zika virus infection, are deferred for 4 weeks after resolution of the symptoms.
NOTE: Refer to CDC’s website for more information on the signs and symptoms of Zika virus infection:
http://www.cdc.gov/zika/symptoms/index.html.
(See February 2016 FDA Guidance: Recommendations for Donor Screening, Deferral, and Product
Management to Reduce the Risk of Transfusion-Transmission of Zika Virus.)
Zika Additional
Question #2
In the past 4 weeks,
have you had 2 or more of the
following symptoms: fever, rash,
joint pain, muscle pain,
conjunctivitis (red eyes),
headache?
No
Accept donor
Yes
Determine 4 week deferral
period based on the date
donor was symptom free.
Defer donor
Next question
Collection Areas WITH Active Transmission of Zika Virus
Additional Question for Zika #3: In the past 4 weeks, have you had sexual contact with a man, who in the
3 months prior to your sexual contact, had Zika virus infection OR had 2 or more symptoms of Zika virus
infection?
Donor Eligibility: The Zika virus can be transmitted from person to person by sexual contact, and the
Zika virus may remain in semen for several weeks. Donors who provide a history of having had sexual
contact with a man who, in the 3 months prior to the sexual contact, has had Zika virus infection OR 2 or
more of the listed symptoms are deferred from donating for 4 weeks following date of last sexual contact.
The symptoms of Zika virus infection are: fever, rash, joint pain, muscle pain, conjunctivitis (red eyes),
headache.
NOTE: Refer to CDC’s website for more information on the signs and symptoms of Zika virus infection:
http://www.cdc.gov/zika/symptoms/index.html.
(See February 2016 FDA Guidance: Recommendations for Donor Screening, Deferral, and Product
Management to Reduce the Risk of Transfusion-Transmission of Zika Virus.)
Zika Additional
Question #3
In the
past 4 weeks, have
you had sexual contact with
a man, who in the 3 months prior to your
sexual contact, had Zika virus infection
OR had 2 or more symptoms
of Zika virus
infection?
No
Accept donor
Yes
Determine 4 week deferral
period based on last date
of sexual contact.
Defer donor
Next question