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CHEMICAL ENGINEERING – Molecular Biorefining: A New Strategy for Fungible Biofuels This research focuses on the development of a innovative approach for producing biofuels that exhibit superior cost, carbon, and sustainability characteristics compared to conventional biofuels. We have engineered industrially relevant microorganisms to produce desaturated fatty-acids, which will be split across the carbon-carbon double bond via inorganic catalysis to produce a high quality diesel molecule along with a chemical co-product (i.e. butanol). The figure below demonstrates the effective production of the desired desaturated Palmitate (C16) molecule. Sugar, Cellulosic Biomass, Syngas Acetyl-CoA Acyl-ACP Δ4 desaturase ∆4-Acyl-ACP thioesterase Palmitate (16:1 Δ4) COOH Hydrogenolysis COOH Reduction Diesel Blend COH or COH Further catalysis to a broad range of industrial Alcohols (Butanol, Ethanol) or Alkanes chemicals and fuels