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DNT 200 NUTRITION FOR HEALTH SCIENCES SPECIALIZED NUTRITION SUPPORT 1 SPECIALIZED NUTRITIONAL SUPPORT "Obstacles are those frightful things you see when you take your eyes off your goal." Henry Ford (1863-1947) 2 SPECIALIZED NUTRITIONAL SUPPORT Algorithm Adequate Nutritional Status Yes Oral Diet; reassess regularly; simple IV’s If status changes Functional GI tract? Yes Appetite/Physical Ability to Eat? Yes Oral Diet; Supplement PRN No Withhold elective therapy; select feeding route No Long-Term Support Anticipated; Severely Malnourished? No Yes Tube Feeding TPN No PPN 3 SPECIALIZED NUTRITIONAL SUPPORT 4 SPECIALIZED NUTRITIONAL SUPPORT • Supplemental nutrition – When a person cannot get enough nutrition from regular meals, the first step is to supplement the diet with extra food between meals • Give snacks the person enjoys • May find it easier to drink than to eat – Liquids seem less filling – Are easy for debilitated people to handle – Examples • • • • Milk Milk shakes Proprietary foods Adding powdered milk to these beverages makes them higher in protein 5 SPECIALIZED NUTRITIONAL SUPPORT • Supplemental nutrition – Palatability can be a problem with long term use -- may need to add flavoring – Serve liquid feedings attractively • Served in a glass is more attractive than a can • Serve it COLD • Tube feedings – Delivers a nutrient solution via tube into the stomach or intestine – Individual should have a functioning GI tract (but may have an inability to ingest enough nutrients to meet present needs) 6 SPECIALIZED NUTRITIONAL SUPPORT • Tube feedings (con’t) – For people who cannot eat oral diets, tube feedings are preferred to feedings by vein wherever possible • Enteral nutrition helps maintain normal gut function – When the gut is not used for a long time, villi shrink and their enzyme activity slows – When the gut is not used for a long time, intestinal bacteria translocate to the portal vein and lymphatic system and cause infection • Enteral feedings are associated with fewer infections • Enteral feedings are less expensive 7 SPECIALIZED NUTRITIONAL SUPPORT • Tube feedings (con’t) – Feeding tube placement • Most commonly inserted through the nose and passed into the stomach or intestine • Can be surgically placed into openings in the esophagus, stomach, or jejunum – Feeding tubes come in a variety of diameters and lengths -- smallest tube through which the feeding will flow is best – Complications • Inadvertent placement of tube in the lungs • Tube obstructions • Can be serious and life threatening 8 SPECIALIZED NUTRITIONAL SUPPORT • Types of formula – Intact formulas • Are appropriate for people who are able to digest and absorb nutrients without difficulty • Can come as either protein isolate (HBV protein that has been separated from a source containing a variety of proteins [e.g. casein, albumin] or blenderized formulas) • Blenderized formulas can be either blenderized or purchased commercially – Hydrolyzed formulas -- are in a sense “pre-digested” and require minimal further digestion 9 SPECIALIZED NUTRITIONAL SUPPORT • Types of formula – Types of commercial formulas available • Ready-to-use liquid • Liquid concentrate • Powdered – Concentration • Standard = 1 kcalorie per cc • 1.5 kcalorie per cc • 2 kcalories per cc – Modular formulas -- contain specific nutrients for use as supplements 10 SPECIALIZED NUTRITIONAL SUPPORT • Types of formula (con’t) – Formula osmolality • Osmolality is the number of molecules and ionic particles (measured in osmoles) per liter of water in a solution • The greater the number of particles in a solution, the greater the osmolality • Normal osmolality of blood serum is about 300 mOsm per liter • Osmolality of formulas range from 250 to over 800 mOsm • A formula that approximates the osmolality of the 11 serum is referred to as an isotonic formula SPECIALIZED NUTRITIONAL SUPPORT • Types of formula (con’t) • A hypertonic formula has a higher osmolality than serum – Can cause water to be drawn from in and around the body cells into the intestine – Not a problem if the body has time to adopt to the hypertonic solution – Can otherwise cause diarrhea, vomiting, cramps or nausea – It is preferable to use a formula that is as nearly isotonic as possible 12 SPECIALIZED NUTRITIONAL SUPPORT • Residue and fiber – Fiber is the portion of the intestinal contents that remain in the colon because people don’t have the enzymes to digest it, e.g. cellulose – Residue is the total amount of material in the colon; includes dietary fiber and also undigested foods, intestinal secretions, bacterial cell bodies, and cells shed from the intestinal mucosa – High fiber diets benefit people who can tolerate them because they maintain gut integrity 13 SPECIALIZED NUTRITIONAL SUPPORT • Other characteristics of formulas – Can be made from many different ingredients • May or may not contain lactose • May or may not include a higher biologic value protein – Cost can vary widely 14 SPECIALIZED NUTRITIONAL SUPPORT • Formula selection – No formula is perfect – Rule of thumb -- the formula that meets the client’s nutrient needs with the least risk of complication at the lowest cost is the one of choice – A formula given orally needs good taste -- the more hydrolyzed and lower its fat content, the less tasty it will be 15 SPECIALIZED NUTRITIONAL SUPPORT • Formula selection (con’t) – Additional factors • The client’s digestive and absorptive function – If the GI tract does not function, the client is not a candidate for oral or tube feeding – People with minimal GI function may benefit from hydrolyzed formulas 16 SPECIALIZED NUTRITIONAL SUPPORT • Formula selection (con’t) – Additional factors • The placement of the feeding tube (stomach vs. intestine) – Feedings delivered directly into the intestine must be easily digested -- however if the GI tract is functional they need not be hydrolyzed – Isotonic feedings are preferred for intestinal feedings 17 SPECIALIZED NUTRITIONAL SUPPORT • Formula selection (con’t) – Additional factors • Nutrient requirements -should be based on careful assessment • Individual preferences and tolerances (food allergies and sensitivities) -- consider lactose intolerance 18 SPECIALIZED NUTRITIONAL SUPPORT • Administration of tube feedings – Prepare formula in a clean environment with clean equipment and clean hands – Store opened or mixed formulas in refrigerator – Discard unlabeled or improperly labeled containers and all opened containers of formulas not used within 24 hours – Deliver formula in a fresh container daily -never add fresh formula to formula still in the container – Before adding formula to a feeding bag or bottle, rinse the feeding container, the tubing attached to it, and the feeding tube itself with 19 water SPECIALIZED NUTRITIONAL SUPPORT • Administration of tube feedings (con’t) – Change the feeding bag or bottle and tubing attached to it (except the feeding tube itself) every 12 to 24 hours – Formulas sometimes come pre-packaged in containers that can be used to dispense formula without being added to another feeding bag -greatly reduces the risk of bacterial contamination 20 SPECIALIZED NUTRITIONAL SUPPORT • Administration of tube feedings (con’t) – Rate of administration and concentration • People with severe stress or those who have not eaten for several weeks may not be able to tolerate large volumes of highly concentrated formulas • Rule of thumb -- people who have low albumin levels (less than 3.5 grams per 100ml) are more likely to have problems tolerating concentrated formulas • Formulas may have to be diluted to 1/2or 1/3 strength and given slowly (30 to 50 ml per hour) 21 SPECIALIZED NUTRITIONAL SUPPORT • Administration of tube feedings (con’t) – Rate of administration and concentration • Increase as tolerated, 25 ml per hour every 8-12 hours • Once the desired flow rate is reached, increase the concentration • If intolerance develops, back up and give the client more time to adapt 22 SPECIALIZED NUTRITIONAL SUPPORT • Administration of tube feedings (con’t) – Water is important • Supplemental water is often needed to meet client’s daily fluid requirements • Guideline -- adults need 1,500 to 2,000 ml of water daily • Indicators – Thirst in alert adults – Body weight changes – High serum electrolytes, hematocrit and blood pressure 23 SPECIALIZED NUTRITIONAL SUPPORT • Administration of tube feedings (con’t) – Water is important • Water should be used to flush the feeding tube before and after a feeding – Prevents the line from being clogged – Hydrates the patient – Give water orally if the person can drink it 24 SPECIALIZED NUTRITIONAL SUPPORT • Administration of tube feedings (con’t) – Delivery of feedings • Bolus feeding – Administered 4 to 6 times per day – Patient can move about freely between feedings • Continuous drip – Delivered slowly over 16 to 24 hour period – Benefits people intolerant of larger feeding volumes – Infusion pumps may be used to assure accurate and constant flow rates • Prevention of complications -- monitor to ensure early detection of problems 25 SPECIALIZED NUTRITIONAL SUPPORT • Administration of tube feedings (con’t) – Delivery of feedings • Feeding tubes used to administer drugs – Tube feedings widely used for people who are seriously ill -- these people also need many medications – Crushing tablets and mixing them with water is a common practice but should be avoided » May clog tube » Some types of tablets should not be crushed -designed to be released more slowly 26 SPECIALIZED NUTRITIONAL SUPPORT • Administration of tube feedings (con’t) – Delivery of feedings • Psychological implications of tube feedings – Feeding becomes merely nourishment, not an expression of personal preference, social pressure, or cultural tradition – Many feel self conscious about how the tube looks and may feel tied down by the feeding equipment 27 SPECIALIZED NUTRITIONAL SUPPORT • Intravenous nutrition – Terms • Intravenous means through a vein • Parenteral nutrition is the delivery of nutrients through a vein, bypassing the intestine • Dextrose is a form of glucose that is especially soluble in water and used in IV solutions 28 SPECIALIZED NUTRITIONAL SUPPORT • Intravenous nutrition – Parenteral IV solutions may consist of some or all of the essential nutrients: • Water • Amino Acids • Dextrose • Lipids • Electrolytes (minerals) • Vitamins • Trace elements 29 SPECIALIZED NUTRITIONAL SUPPORT • Intravenous nutrition – Simple IV solutions generally provide • Water • Dextrose • Electrolytes • Three liters provide about 510 kcalories per day ***** 30 SPECIALIZED NUTRITIONAL SUPPORT • Intravenous nutrition – IV fat emulsions and peripheral total parenteral nutrition • Peripheral veins are the smaller diameter veins that bring blood to the extremities(arms and legs) • Simple glucose solutions containing only amino acids fall short of meeting total nutrient needs • IV fat emulsions make it possible to deliver needed nutrients by peripheral vein – Provides a concentrated source of kcalories – IV fat is isotonic -- does not irritate veins – Provides essential fatty acids **** 31 SPECIALIZED NUTRITIONAL SUPPORT • Intravenous nutrition (con’t) – Peripheral TPN cannot deliver quite enough nutrients for people with very high energy needs - is suitable for short term (7-14 days) nutritional support *** 32 SPECIALIZED NUTRITIONAL SUPPORT • Intravenous nutrition (con’t) – TPN by central vein • Abbreviated TPN • IV catheter surgically placed in a large diameter central vein • Enables quick dilution of concentrated solutions -- by the time these solutions reach the peripheral veins, they are not so irritating • Advantage -- concentrated solutions of nutrients can be delivered to people who cannot or should not be fed through the GI ** 33 tract SPECIALIZED NUTRITIONAL SUPPORT • Intravenous nutrition (con’t) • Actual concentrations of formula determined by each person’s unique nutritional needs • Electrolytes, trace elements, and fat can be added • Other possible additions – Albumin – Heparin -- prevents clots from forming on the catheter that might obstruct the flow of formula – Insulin -- to help regulate blood glucose levels • Like a tube feeding, TPN should be started slowly to give the client time to adjust to the high glucose concentrations and the osmolality of the TPN * formula 34 SPECIALIZED NUTRITIONAL SUPPORT • Intravenous nutrition (con’t) • Possible indications for TPN – Major small bowel resections – Severe diarrhea – Inflammatory bowel diseases – Moderate to severe pancreatitis – Severe malnutrition when the GI tract is non-functional 35