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1 Nervous System Emergencies Chemeketa Community College Paramedic Program 2 Causes of Coma (We’ll be talking about these…) • Structural • Metabolic • Drugs • Cardiac (Shock, Arrhythmias, Hypertension, Stroke • Respiratory (Toxic Inhalations, COPD) • Infectious Process (Meningitis) 3 And these….. • Amyotrophic lateral sclerosis (ALS) • Muscular Dystrophy • Bell’s Palsy • Multiple Sclerosis • Parkinson’s • Peripheral neuropathy • Central pain syndrome 4 The nervous system • CNS – 43 pairs of nerves – Brain • 12 pairs of cranial nerves – Spinal cord • 31 pairs of spinal nerves • PNS 5 • Neurons – Dendrites, soma, axon, synapse • Neurotransmitters – Acetylcholine, norepi, epi, dopamine • Skull - brain • Spine - spinal cord • Meninges – Dura mater, arachnoid membrane, pia mater • Cerebrospinal fluid 6 Brain • Cerebrum • Frontal lobe • Temporal lobe • Parietal lobe • Occipital lobe • Cerebellum 7 8 9 Brainstem • Brain stem – – – – Medulla Pons Midbrain Reticular formation • Diencephalon – Hypothalamus – Thalamus – Limbic system 10 Blood supply to brain • Vertebral arteries – Through foramen magnum – Cerebellum – Basilar artery – pons and cerebellum, cerebrum • Internal carotid arteries – Carotid canals – Anterior cerebral arteries – Frontal lobes, lateral cerebral cortex, posterior cerebral artery • Circle of Willis 11 Ventricles • Lateral ventricle • Third ventricle • Fourth ventricle 12 13 14 15 16 17 Spinal Cord • 17-18 inches long!! To first lumbar vertebra • Reflexes • Afferent - sensory • Efferent - motor • Interneurons - connecting 18 Peripheral Nervous System • Cranial nerves • Somatic sensory • Somatic motor • Visceral sensory • Visceral motor • Brachial plexus 19 Cranial nerves “Some say marry money, but my brother says bad boys marry money." • I Olfactory – smell • II Optic – vision • III Oculomotor – Constriction, movement • IV Trochlear – Downward gaze • V Trigeminal – Facial sensation, chewing • VI Abducens – Lateral eye movement • VII Facial – Taste, frown, smile • VIII Acoustic – Hearing, balance • IX Glossopharyngeal – Throat, taste, gag, swallowing • X Vagus – Larnx, voice, decreased HR • XI Spinal Accessory – Shoulder shrug • XII Hypoglossal – Tongue movement 20 Learn the cranial nerves • • • • • • • • On Olfactory Old Optic Olympus Oculomotor Towering Trochlear Top, Trigeminal A Abducens Finn Facial And Acoustic • German Glossopharyngeal • Viewed Vagus • Some Spinal Accessory • Hops Hypoglossal OR…… 21 Autonomic Nervous System • Sympathetic – Fight or Flight • Parasympathetic – Feed or Breed 22 23 Initial Assessment Be organized and systematic • • • • • • Mentation Ensure patent airway Spinal precautions prn Monitor for respiratory arrest, vomiting Oxygenate If ventilating with BVM, use NORMAL rate – PCO2 – SaO2 24 Assessment – History Be organized and systematic! • • • • General health Previous medical conditions Medications History with complaint • Bystanders / Family – Length of Coma, Sudden or Gradual Onset, Recent Head Trauma, Past medical hx, alcohol/drug use or abuse, complaints before coma 25 What led up to 9-1-1? • Time of onset • Seizure activity • Environment • Cold, hot, drug paraphernalia • Medications / Medic Alerts 26 Assessment - Physical • General appearance • Mentation – Mood – Clarity of thought – Perceptions – Judgment – Memory & attention 27 Assessment - Physical (cont.) • Speech – Aphasia • Apraxia • Skin • Posture, balance and gait • Abnormal involuntary movements 28 Assessment - Physical • Vital signs – Hypertension – Hypotension – Heart rate (fast, slow) – Ventilation (rate, quality) – Temperature, fever • Cushing’s Triad 29 Assessment - Physical (cont.) • Head / neck – Facial expression – Eyes • Acuity, fields, position & alignment, iris, pupils, extraocular muscles 30 31 Assessment – Physical (cont.) – Ears • Acuity – Nose – Mouth • Odors • Thorax and lungs – Auscultate 32 Assessment - Physical (cont.) • Cardiovascular – Heart rate – Rhythm – Bruits – Jugular vein pressure – Auscultation – ECG monitoring 33 Assessment - Physical (cont.) • Abdomen • Nervous – Cranial nerves – Motor system • Muscle tone, muscle strength, flexion, extension, grip, coordination • Assessment tools – Pulse Oximetry, End tidal CO2, Blood Glucose 34 Assessment • Ongoing assessment 35 Management • Airway and ventilatory support – Oxygen – Positioning – Assisted ventilation – Suction – Intubation • Circulatory support – Venous access 36 Management (cont.) • Non-pharmacological interventions – Positioning – Spinal precautions 37 Pharmacological interventions • • • • • • • • Anti-anxiety agent Anti-convulsant Anti-inflammatories Diuretic Sedative-hypnotic Skeletal muscle relaxant Hyperglycemic Anti-Emetic 38 Management (cont.) • Psychological support • Transport considerations – Mode – Facility 39 Head to Toe • Pupils • Respiratory Status • Spinal Evaluation 40 Pupils • Cranial nerve III (occulomotor) • Brain herniation = same side dilation • Both dilated = anoxia, brain stem injury • Anisocoria = unequal pupil – normal? 41 Cardinal Positions of Gaze • Patient should be able to follow your finger • Conjugate gaze - structural lesion – Irritable focus - away – Destructive focus – toward • Dysconjugate gaze – brainstem dysfunction 42 Respiratory Status • Cheyne-Stokes – Brain Injury • Central Neurogenic Hyperventilation – Cerebral Edema 43 Respiratory Status (cont.) • Ataxic – CNS Damage = poor thoracic control • Apneustic – Damage to upper Pons 44 Respiratory Status (cont.) • Diaphragmatic – C-spine • Kussmaul – DKA 45 Spinal Evaluation • Tingling (pins & needles) • Loss of Sensation or Function • Pain, Tenderness • Priapism • Deformity, tight neck muscles 46 Spinal Evaluation (cont.) • Motion, Sensation, Position/each extremity • “Gas pedal”, grips • If unconscious, pain response • Incontinence, rectal for S-1 47 Neurological Exam • Decorticate Posturing – Above Brainstem • Decerebrate Posturing – Brainstem • Flaccid • Babinski’s sign 48 Neurological Exam • Glascow Coma Scale – Motor, 1 - 6 – Verbal, 1 - 5 – Eye, 1 - 4 49 50 Altered Mental Status/Coma • Structural Lesions – Acute onset – Unresponsive/asymmetric pupillary response • Toxic - Metabolic States – Slow onset – Preserved pupillary response 51 Causes of Coma Structural • Trauma, Tumor • Epilepsy, Hemorrhage • Other Lesions 52 Causes of Coma - Metabolic • Anoxia, Hepatic Coma • Hypoglycemia, DKA • Thiamine Deficiency • Kidney, liver failure • Seizure 53 Causes of Coma - Drugs • Barbiturates, Narcotics • Hallucinogens • Depressants • Alcohol 54 Causes of Coma - Cardiovascular • Hypertensive Encephalopathy • Dysrhythmias, Cardiac Arrest 55 Causes of Coma - Respiratory • COPD • Toxic Gases 56 Causes of Coma - Infections • Meningitis • Encephalitis • AIDS Encephalitis 57 AEIOU - TIPS • A = Alcohol, Acidosis • E = Epilepsy • I = Infection • O = Overdose • U = Uremia 58 AEIOU - TIPS • T = Trauma, Tumor • I = Insulin • P = Psychosis • S = Stroke 59 Management • C-spine • Airway • Oxygen • Hyperventilate if ICP is up??? 60 Management • D50 - 25 grams • Narcan - 2.0 mg • Thiamine 100 mg 61 62 Seizures • Behavioral alteration due to massive electrical discharge. • Generalized or Partial 63 Generalized • Grand Mal • Petit Mal 64 Partial Seizures • Simple or Complex (Psychomotor) • May spread to generalized 65 Causes • Brain Injury, Epilepsy, Tumor • Hypoglycemia, Hyperthermia • Eclampsia • Hypoxia 66 Grand Mal (generalized) • Aura, Loss of consciousness • Tonic, Hypertonic Phases • Clonic • Post-Seizure, Post-Ictal 67 Other Types • Focal Motor - One Area of the Body • Psychomotor - Auras • Petit Mal, 10-30 Seconds • Hysterical - How Do You Tell? 68 Management • Good history and physical first • ABCs • IV, EKG, BG • Body Temp, Position on Side • Suction if needed • Calm, Quiet 69 Status Epilepticus • Two or More Seizures • Consciousness Not Regained • Non-compliance With Meds 70 Management of Status Seizures • 100% O2, BVM • IV, EKG, BG • D50, Thiamine (if needed) • Valium 5-10 mg (or Versed 0.5 – 1.0 mg) 71 72 Coma • Abnormally deep state of unconsciousness – Structural lesions – Toxic metabolic states 73 DDX Structural lesions Commonly asymmetrical neurological signs Acute onset Unresponsive or asymmetrical pupillary responses Toxic-metabolic coma Neurological findings symmetrical Coma slow in onset Preserved pupillary response 74 Management • Supportive • Prevention • Medication administration 75 Stroke (CVA) - what do they look like? • Motor, Speech, Sensory Centers • Altered mentation • Upper Airway Noises • Unequal Pupils, Visual Disturbances • Hemiparalysis / Hemiparesis 76 Stroke (CVA) • Eyes Deviate Away From Paralysis, or Look Toward Lesion • Dysphagia • Dysphasia 77 Ischemic or Hemorrhagic?? • Most common • Usually 2ndary to tumor or atherosclerosis • Slow onset • Long history • May be assoc. with Af • Hx angina, previous CVA • Least common • Usually 2ndary to aneurysm, AV malformation, HTN • Abrupt onset • Commonly during stress • May be assoc. with cocaine • May be asymptomatic 78 before rupture Transient Ischemic Attacks (TIA) • Little Strokes, Emboli, Carotid Disease • Stroke Symptoms Gone in a Day • Usually Mean a Big One Is on the Way 79 Cincinnati Prehospital Stroke Scale • Facial droop • Arm drift • Speech “you can’t teach an old dog new tricks” 80 81 Management CVA / TIA • Protect Patient • ABCs / C-spine • ETT? BVM? OPA? • Hyperventilate if unresponsive 82 Management CVA / TIA • CBG, IV, EKG • Reassure, calm (they can hear, usually) • Position, Transport 83 84 Headaches • Tension – Muscle contractions • Migraines – Constriction, dilation of blood vessels; seratonin or hormone imbalance? • Cluster – Bursts; occur during sleep • Sinus – Allergies or infection/inflammation of membranes 85 Management of H/A • Tension – Aspirin, acetaminophen, ibuprofen • Migraines – Beta blockers, calcium channel blockers, antidepressants, serotonin-inhibitors • Cluster – Antihistamines, corticosteroids, calcium channel blockers • Sinus – Antibiotics, antihistamines, analgesics 86 Muscular Dystrophy • Inherited • Progressive degeneration of muscle fibers • Duchenne MD most common (1-2/10,000 male children) • No Tx • Death usually from pulmonary infection, before age 21 87 Multiple Sclerosis • Gradual destruction of myelin in brain and spinal cord • Autoimmune? • 1/1000 (women 3/2 men) 88 Parkinson’s Disease • Degeneration or damage to nerve cells in basal ganglia; 130/100,000 • Lack of dopamine prevents control of muscle contraction • Progressive • Initial; slight tremor in one extremity – Shuffling gait – Untreated, severe incapacity in 5-7 years 89 Central Pain Syndrome • Infection/disease of trigeminal nerve – Paroxysmal episodes of severe unilateral pain • • • • Lips Cheek, Gums Chin • Pt usually older than 50 • Trigger point • Treated with tegratol 90 Bell’s Palsy • Inflammation of 7th cranial nerve • Sudden onset • Usually temporary, usually 2ndary to infection including Lyme disease, herpes, mumps, HIV • 1/60-70 91 Bell’s Palsy, cont. • Sx; – Eyelid, corner of mouth droops – Taste may be impaired • Tx: – Corticosteroid, analgesics 92 Amyotrophic Lateral Sclerosis • Motor neuron disease – Pt usually over 50; more common in men • Sx; first, weakness in hands and arms with fasciculations • Late – pt unable to speak, swallow, move • Awareness, intellect maintained. • Death usually w/in 2-4 years /p Dx 93 Peripheral Neuropathy • Affects peripheral nervous system incl. Spinal nerve roots, cranial nerves – – – – – – – – Diabetes Vit. B deficiencies Alcoholism Uremia Leprosy Drugs Viral infections Lupus 94 Nervous System Emergencies SUMMARY • Complex and Varied • Attention to Assessment • Attention to Treatment • Good History and Exam • Good Documentation 95 S:\HealthOccupations\EMS\EMT Paramedic\Neuro\Nervous System emergencies.ppt 96