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Nausea and Vomiting A Palliative Approach to Care Nausea and vomiting • Nausea is the unpleasant feeling of the need to vomit. • Vomiting is the expulsion of stomach contents from the mouth • Distinction helps with accurate assessment and management Causes of Nausea and Vomiting • Iatrogenic - medications, chemotherapy, radiotherapy • Metabolic - hypercalcaemia, urinary tract infection, altered taste • Organic - constipation, bowel obstruction Causes of Nausea and Vomiting • Psychological - anxiety, anticipatory • Other - odour from food or wounds • Cause is often unknown at end of life Constipation and nausea • Constipation – a major cause Due to: – Reduced fluid intake – Low fibre diet – Decreased mobility – Medication Other Causes of N & V • Medications which slow gastrointestinal motility due to colonic slowing or gastroparesis • Poor neuromuscular coordination may affect residents with diabetes, stroke • Positional changes in neck due to weight loss Assessment history • Establish whether the resident is vomiting • Description of the vomiting • What precipitates nausea and vomiting? • Is there a pattern? • What eases the nausea and vomiting? • Check for constipation Non-pharmacological therapy • Correct reversible causes • Environmental factors - fresh air, absence of offensive smells • Offer non-odourous foods, eat slowly & small amounts frequently • Avoid lying flat before and after meals • Diversional therapies - relaxation Oral care • Maintain good mouth care is important part of management: – water and toothpaste – small soft brush – soaking dentures in weak non-toxic solution – artificial saliva eg. oralbalance Pharmacological management General guidelines include: • Determine the most likely cause • Identify contributing factors • Select an appropriate anti-emetic • Consider possibility of toxicity • Possible benefit of treatment versus potential burden Pharmacological management Pharmacological interventions: • ensure patient compliance • evaluate regularly • give prophylactically • select appropriate route for drug administration Pharmacological management If cause is gastrointestinal – poor gastric emptying, use of: • Prokinetic agent • Metroclopromide • Cisapride • Domperidone Pharmacological management If cause is affected by psychological issues: • diazepam • alprazolam • lorazepam may block physical manifestations of anxiety Pharmacological management If cause is intracranial with pressure related to tumour • dexamethasone • haloperidol • cyclazine Hyperacidity • Hyperacidity can cause nausea and or vomiting • Can produce heartburn, acidity or bitter taste • Treatment – non absorbable antacids • Histamine H2-receptor antagonist (ranitidine) • Proton pump inhibitor (omeprazole) Summary • Nausea and vomiting can occur independently • Important to identify and treat reversible causes • Constipation a major cause of nausea in RACF • Pharmacological and non-pharmacological therapies