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Senior Adult Oncology Overview Cancer is the leading cause of death for those 60-79 years 60% of all cancers occur in patients who are 65 years or older Older individuals are more prone to develop cancer due to physiological changes associated with aging Older Adults Older patients can be classified into three categories: Young Old: 65-75 years Old: 76-85 years Oldest Old: over 85 years Age Distribution of U.S. Population, 1980, 1990, and 2005 Year 1980 85+ 80-84 75-79 70-74 65-69 60-64 55-59 50-54 45-49 40-44 35-39 30-34 25-29 20-24 15-19 10-14 5-9 0-4 Data source: The Bureau of the Census Year 1990 Year 2005 Frailty Decreased reserve and resistance to stressors Frail patients have an increased risk of complications from cancer treatments Risk for falling, disability, hospitalization, and death Fraility Criteria Unintentional weight loss (10 lbs or more in past year) Self reported exhaustion Weakness Slow walking speed Low physical activity Geriatric Syndromes Malnutrition Depression Polypharmacy Dementia Lack of Social Support Fall Risk Falls One of the most common geriatric syndromes 30-40% of adults older than 65 years fall each year Risk factors: muscle weakness and impairments in gait, vision, cognition, and ADLs Activities of Daily Living (ADLs) Able to bathe self Able to dress self Able to toilet self Control over bowel & bladder Able to transfer self Able to feed self Instrumental Activities of Daily Living (IADLs) Use the telephone Get to places beyond walking distance Grocery shop Prepare meals Housework Laundry Take medications Manage money Percent of Medicare Beneficiaries Reporting Difficulty with IADLs or ADLs by Age, 2004 35 30 Percent (%) 25 20 15 10 5 0 65-74 75-84 IADL Only Data Source: Medicare Current Beneficiary Survey 1 to 2 ADLs 85 years and over 3 to 6 ADLs Percent of Persons Age 65 and Over (age-adjusted) Reporting Selected Chronic Conditions by Sex, 2004-2005 60 Male Female 50 Percent (%) 40 30 20 10 0 Hypertension Arthritis Data Source: National Health Interview Survey Heart disease Cancer Diabetes Years of Education Among Persons Age 65 and Over (age-adjusted) by Sex and Race/Ethnicity, 2006 70 Female Male Percent (%) 60 50 40 30 20 10 0 Less than High School High School More than High Less than High School School White non-Hispanic Data source: Current Population Survey Black non-Hispanic High School Hispanic More than High School Cancer Treatment Benefits: Prolonged survival Maintenance and improvement of quality of life and function Palliation of symptoms Cancer Treatments Risks: Complications of surgery, radiation, and/or chemotherapy Affects on cognition, function, balance, vision, hearing, continence, and mood Treatment Decisions Life Expectancy Aggressiveness of Disease Functional Abilities Comorbidities Patient Goals Social Resources Tolerance of Treatment Treatment Decisions Advanced age alone should not preclude the use of effective cancer treatment Older patients with good performance status are able to tolerate most forms of treatments Treatment that diminishes quality of life with no significant survival benefit should be avoided