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The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH If patient changes suddenly …. Search for occult infection, e.g., urinary tract infection (UTI) Review medication list for potentially contributory medications or potentially harmful interactions Rule out drug or alcohol withdrawal Support referrals to geriatrics, pharmacy, internal medicine The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH Case Study Mrs. Smith is a 91 years old lady admitted from R.H. with low back pain The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH History of presenting illness sudden increase in low back pain 3 days ago; unable to walk new onset of urinary incontinence at home GP started Lorazepam 1 mg Q HS 5 days ago for poor sleep confusion over 48 hours –disoriented to time, not consistently recognizing family The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH Course in the hospital indwelling Foley catheter inserted not sleeping well – she is awake during the night and sleeping much of the day takes pain medication regularly due to low back pain not drinking or eating much stays in bed most of the day The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH Past Medical History Hypothyroidism Dyslipidemia Hearing loss Macular degeneration Hypertension ?TIA Arthritis Chronic Low Back Pain Degenerative Disc Disease, Scoliosis The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH Social History Widowed, 3 children, 9 grandchildren Retired teacher – grade school and ESL Enjoys listening to music, attending socials and visiting with families The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH Baseline Function Walks with walker independently to D/Room Toilets independently; no history of incontinence Assisted with bath 2 x per week 1 year history of short term memory loss, repeats stories, forgets family visits The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH Investigations X Ray spine: no obvious fracture except for possibly a displaced right transverse process fracture of L3 Urine C & S: result pending CT Head: mild cerebral atrophy, moderate ischemic change in the white matter, no acute infarct or intracranial hemorrhage The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH Blood work Lab Findings Normal Range urea 11.2 3.0-6.5 mmol/L Creat 115 60-115 umol/L TSH 18 12-22 pmol/L WBC 13,3 4.0 – 11.0 x 10 9/L Hgb 130 130-180 g/L Albumin 23 35 - 50 g/L Medications Aspirin 81 mg OD Lorazepam 1 mg Q HS Baclofen 10 mg TID Levothyroxine 0.125 mg OD Hydrochlorothiazide 25 mg OD Lipitor 20 mg OD Fosinopril 20 mg OD Colace 100mg BID Senokot 2 tabs Q HS Tylenol # 3 1-2 Q 4 H PRN The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH What are Mrs. Smith’s risk factors for delirium and functional decline? a) Age o True o False b) ADL impairment o True o False c) Dehydration o True o False d) Vision impairment o True o False d) Hearing Impairment o True o False The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH What medications could contribute to her confusion? a) Baclofen 10 mg TID o True o False b) Levothyroxine 0.125 mg OD oTrue o False c)Lorazepam 1 mg Q HS oTrue o False d) Tylenol # 3 1-2 Q 4 H PRN oTrue o False The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH Based on the clinical presentation and blood work what would you suspect as the most likely cause of Mrs. Smith’s cognitive and functional decline? a) Displaced right transverse process fracture of L3 o True o False b) Arthritis flare up o True o False c) Urinary Tract Infection o True o False d) Hypothyroidism o True o False The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH Based on Mrs. Smith’s history and her current clinical presentation she is most likely experiencing… a) Delirium o True o False b) Dementia o True o False The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH Distinguishing Delirium from Dementia Delirium Dementia Onset Hrs – days Months Fluctuations Within a day Within days Attention Impaired Not until Severe Disorganized thinking Usually present Memory Impairment Level of Consciousness Often impaired Not until Severe Adapted from Rudolph, J.L, Marcantonio, E.R., Geriatrics & Aging 2003: 6(10): 14 – 19. I WATCH DEATH I - Infections W - Withdrawal A – Acute Metabolic T – Toxins C – CNS Pathology H – Hypoxia D – Deficiencies E – Endocrine A – Acute Vascular T – Trauma H – Heavy Metals The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH HELP CNS Assessment Cognitive Assessment SMMSE Mini-Cog Confusion Assessment Method Digit Span Test The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH HELP CNS Assessment Functional Assessment Mobility status Fall’s risk Continence Emotional Health Discharge barriers Nutritional status The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH HELP Interventions Mrs. Smith Delirium Protocol (suggest to D/C Lorazepam, Tylenol #3, Baclofen; routine urinalysis done on admission ) Recommend more blood work( B12, calcium, glucose, lytes) Early mobilization Protocol Fluid Repletion protocol Vision protocol Hearing Protocol Referrals to OT, PT, SW, RD, Geriatrician The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH HELP Interventions Mrs. Smith Remove catheter, check for voiding Check for constipation Regular Pain Assessment Sleep Enhancement Protocols Discharge Planning The Hospital Elder Life Program © 2000, Sharon K. Inouye, MD, MPH