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NAVIGATING DECISIONS ABOUT LIFE-SUSTAINING TREATMENTS KRISTEN CHASTEEN MD PALLIATIVE MEDICINE, HENRY FORD HOSPITAL OBJECTIVES • Recognize that eliciting a patient’s values is the first step in making decisions about life sustaining treatments • Describe an overview of common life-sustaining medical treatments • CPR • Mechanical ventilation • Artificial nutrition and hydration • Describe some of the risks and benefits of lifesustaining therapies FACTORS INFLUENCING DECISIONS Values Emotions Decisions about lifesustaining treatments Faith Medical facts RISKS AND BENEFITS MARY • 80 year-old woman • History of diabetes, mild kidney disease and now has a new diagnosis of early Alzheimer’s dementia • Hospitalized once in the past year for a serious bladder infection • Lives alone in an apartment since her husband died 8 years ago • Daughter, Julie, lives nearby and visits several times a week • Faith is important to her and she is an active member of a Presbyterian church VALUES • Independence • Recognize and communicate with family, friends • Strong faith in God and belief in miracles also influences decision making CARDIOPULMONARY RESUSCITATION (CPR) • When Mary was in the hospital last time, the doctor asked her about her code status • Full code – in the event of cardiac arrest, CPR should be attempted • DNR/DNAR/Do not resuscitate - in the event of cardiac arrest, CPR should not be attempted CARDIAC ARREST • Loss of heart function, breathing, and consciousness • The heart's electrical system malfunctions and the heart stops pumping blood to the rest of the body • Results in death without immediate treatment CARDIOPULMONARY RESUSCITATION (CPR) • Pressing hard and fast on the center of the chest to pump blood through the body CARDIOPULMONARY RESUSCITATION (CPR) • CPR also involves • Pushing oxygen into the lungs by a mask or by inserting a breathing tube • Defibrillation • Intravenous medications INTUBATION • Inserting a breathing tube down the mouth into the windpipe (trachea) and pushing oxygen into the lungs using a machine called a ventilator DEFIBRILLATION • Using electric shocks to restart the heart INTRAVENOUS MEDICATION • Putting strong medications like epinephrine into the vein to help restart the heart OUTCOMES • Cardiac arrest out of the hospital • 10% survival to hospital discharge • Cardiac arrest in the hospital • 20% survival to hospital discharge • ½ of survivors will have minimal or no brain damage • Patients with lower chance of survival • • • • Older, frail, chronic medical illness Live in a nursing facility Kidney or liver problems Widespread (metastatic) cancer BENEFIT • Chance of survival to be well enough to leave the hospital • Chance of returning to previous health state and level of functioning RISKS • High chance of dying in an ambulance, emergency room, or intensive care unit (ICU) • Interferes with family presence at the time of death • Patient pain and suffering during CPR • Patient pain and suffering from additional procedures during an ICU stay after the arrest • Prolonged dying process may be burdensome for family • Chance of survival with brain impairment or reduced level of functioning CPR • http://www.acpdecisions.org/products/videos/ MARY'S CHOICE MARY • Mary lives for another 5 years and progresses to advanced dementia • Unable to get out of bed • No longer recognizes friends and family and barely speaks • Lives in a skilled nursing facility • Eating very little • Transferred to the hospital after developing pneumonia VENTILATOR • A tube is inserted down the mouth into the windpipe (trachea) and a machine is used to push oxygen into the lungs • Not able to eat or talk • Often given sedating medications to ease discomfort • Tracheostomy: If a ventilator is used long-term, a surgery may be performed to make a hole in the windpipe (trachea) and insert a tube to connect to the ventilator BENEFITS • Supports breathing while an acute illness (like infection) is treated • May allow full recovery to previous health state • Some people with brain, spinal cord, or nerve diseases may have breathing problems many years before the end of their lives and a ventilator may help them live longer and enjoy additional years of satisfying life RISKS • Someone with advanced incurable illness is much less likely to survive or return to their previous health state • Pain from the breathing tube and other procedures in the ICU • Worsening confusion • Restraints JULIE SPEAKS FOR MARY MARY • Admitted to the hospital • Given IV antibiotics to treat her lung infection • Given small doses of morphine to ease her discomfort from difficulty breathing • Recovers from her infection, but not able to eat • A swallowing test shows that when she swallows, food goes into her lungs • Julie asks about a feeding tube TUBE FEEDING • When a person cannot swallow or is too sick to eat, a feeding tube delivers liquid nutrition formula directly into the stomach • A temporary tube can be placed through the nose into the stomach (NG tube) • A long-term tube can be placed by a surgery through the skin into the stomach or intestines (PEG tube) BENEFITS • For people with a temporary serious illness, a feeding tube can allow adequate nutrition until they are able to recover and eat on their own • For people with a blockage in their throat or esophagus, a feeding tube may bypass the blockage • Some people with brain or nerve diseases may lose the ability to swallow many years before the end of their lives and a feeding tube may help them live longer RISKS • • • • • Infections Bleeding Tube leaking Diarrhea, cramping Nausea and vomiting FOR PEOPLE WITH ADVANCED DEMENTIA OR AT THE END OF LIFE • Can cause agitation and cause restraints to be needed to prevent pulling at the tube • Do not prevent aspiration of saliva into the lungs or recurrent lung infections • Do not extend life • Can cause swelling in the body, diarrhea, stomach pain, and fluid in the lungs ARTIFICIAL HYDRATION • Medical treatment that provides water and salt (saline) to someone who is too sick to drink enough on their own or who has problems swallowing • Given by an IV in a vein or under the skin ARTIFICIAL HYDRATION AT THE END OF LIFE • People stop drinking as part of the natural dying process • People who are very near the end of life usually do not feel thirst • Can cause swelling, fluid build-up in the lungs and back of the throat, nausea or vomiting MARY • Enrolls in hospice care and returns to the nursing home • Sponge swabs used to prevent dry mouth and lotion to prevent dry skin • Small doses of morphine used as needed to continue to allow her to breath comfortably • Dies with Julie at her bedside one week later REFERENCES 1. 2. 3. 4. 5. 6. Cervo FA, Bryan L, Farber S. To PEG or not to PEG: A review of evidence for placing feeding tubes in advanced dementia and the decision-making process. Geriatrics. 2006;61(6):30-35. Coalition for Compassionate Care of California http://coalitionccc.org/ Daya MR, Schmicker RH, Zive DM, et al. Out-of-hospital cardiac arrest survival improving over time: Results from the resuscitation outcomes consortium (ROC). Resuscitation. 2015. doi: S0300-9572(15)00063-5 [pii]. Ebell MH, Jang W, Shen Y, Geocadin RG, Get With the Guidelines-Resuscitation Investigators. Development and validation of the good outcome following attempted resuscitation (GO-FAR) score to predict neurologically intact survival after in-hospital cardiopulmonary resuscitation. JAMA Intern Med. 2013;173(20):1872-1878. doi: 10.1001/jamainternmed.2013.10037 [doi]. El-Jawahri A, Mitchell SL, Paasche-Orlow MK, et al. A randomized controlled trial of a CPR and intubation video decision support tool for hospitalized patients. J Gen Intern Med. 2015. doi: 10.1007/s11606-015-3200-2 [doi]. Girotra S, Nallamothu BK, Spertus JA, et al. Trends in survival after in-hospital cardiac arrest. N Engl J Med. 2012;367(20):1912-1920. doi: 10.1056/NEJMoa1109148 [doi]. QUESTIONS?