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Risk factor definitions 02 RISK FACTOR Intrinsic risk factor Extrinsic risk factor …is related to an individual’s own actions …is an integral part of and environment the individual and Something that increases (tobacco, pollution, the chances of getting cannot be changed diet, etc.) a disease (genetics, age, etc.) Risk factors are multiple and differ according to the cancer type Smoking tobacco Radiation Chemicals RISK FACTORS Hereditary Viruses Age HPV EBV HBV General health Hormones Diet Obesity Sun exposure Bacteria H.pylori Absolute risk vs. Relative risk Absolute risk Relative risk The risk of an individual developing cancer during their entire lifetime The risk of a group of people developing cancer in comparison to another group Benefits of assessing risk ! Allows the individual at risk to undertake prevention strategies (e.g. stop smoking, avoid radiation) ! Alerts physicians to those individuals at risk of developing cancer ! Enables screening procedures to detect cancer at an early stage ! Early detection enables physicians to initiate treatment, whist the tumour is still in the initial stages