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Respiratory System Courtney Shelton CST, BA ST Objectives Identify respiratory tracts Identify structures of respiration Discuss respiration and mechanics of breathing Discuss the exchange of gases Discuss volumes Discuss neurological control Overview The organs of the respiratory system perform two basic funtions Air distribution Gas exchange Overview In addition to air distribution and gas exchange, the respiratory system: Filters air Warms air Humidifies air Overview Respiratory organs (or organs associated with the respiratory system such as the sinuses) also influence speech production and make olfaction possible. Structural Plan Organs Nose Pharynx Larynx Trachea Bronchi lungs Structural Plan The basic design is that of a tube with many braches ending in millions of extremely tiny, very thin-waled sacs called alveoli. Air distribution system is like an upside down tree. Structural Plan Alveoli function to exchange gases by distributing the air close enough to blood for the gas exchange to occur. The alveoli can do this because of 2 characteristics. The wall of each alveolus is made of a single layer of cells. The thin barrier is called the respiratory membrane. There are millions of alveoli. Respiratory Tracts Divided into upper and lower. Upper respiratory tract includes: Nose Pharynx Larynx Lower respiratory tract includes: Trachea Bronchial tree Lungs Respiratory Mucosa Defined as the membrane that lines most of the air distribution tubes in the system. WARNING! Don’t confuse this with the respiratory membrane! It separates the air in the alveoli from the blood in surrounding capillaries. Respiratory Mucosa The layer of protective mucus that covers a large portion of the membrane that lines the respiratory tree serves as the most important air purification mechanism. It forms a mucus blanket. Cilia Cilia move mucus from the lower portions of the bronchial tree upward toward the pharynx. Cilia only beat in one direction. Cigarette smoke paralyzes cilia causing an accumulation of mucus resulting in a smoker’s cough. Nose Air enters through the external nares or nostrils. It flows into left and right nasal cavities, which are lined with respiratory mucosa. Nasal septum separates the two cavities. Four paranasal sinuses drain into the nasal cavities. They are: frontal, maxillary, sphenoidal, and ethmoidal. Nose The paranasal sinuses are lined with a mucous membrane that assists in the production of mucus for the resp tract. They also lighten the skull and serve as resonant chambers for the production of sound. Pharynx Most people call this the throat! It is divided into three portions Nasopharynx- uppermost Oropharynx- behind mouth Laryngopharynx- lowest segment Pharynx Air and food pass through this structure. The left and right auditory tubes open into the nasopharynx. They connect the inner ear with the nasopharynx. The connection permits equalization of air pressure between the middle and inner ear. Pharynx Pharyngeal tonsils are located in the nasopharynx. Palatine tonsils are located in the oropharynx. Larynx Voice box Composed of several layers of cartilage. The largest is the thyroid cartilage (Adam’s apple). Two short fibrous bands, the vocal cords, stretch across the interior of the larynx. When they are tense, the voice is high pitched. Larynx Glottis- the space between the vocal cords. Epiglottis- cartilage that partially covers the opening of the larynx. Acts like a trap door that closes during swallowing to prevent food from entering the trachea. Trachea Windpipe Extends from larynx to the bronchi Functions as a passageway for air C-shaped rings with soft tissue in between them Bronchi, Bronchioles, Alveoli Trachea is the main trunk of the chair Primary bronchi are the right and left bronchus. They are the first branches off the trachea. In each lung, they branch into smaller or secondary bronchi whose walls are kept open by rings of cartilage. Bronchi, Bronchioles, Alveoli The secondary bronchi divide into smaller and smaller tubes. Ultimately, these tubes branch into tiny tubes whose walls only have smooth muscle. These tiny tubes are bronchioles. The bronchioles subdivide into microscopic tubes called alveolar ducts which resemble the main stem of grapes. Each alveolar duct ends in several alveolar sacs, which look like a bundle of grapes. Each grape is an alveoli. Alveoli Effective in gas exchange Extremely thin walled Lie in contact with capillaries Millions in each lung Surface of the respiratory membrane inside the alveolus is covered by surfactant that reduces surface tension in the alveoli and keep them from collapsing as air moves in and out Lungs and Pleura Lungs Right has 3 lobes Left has 2 lobe Apex is the narrow, superior portion under the collarbone Base rests on the diaphragm Lungs and Pleura Pleura Covers outer surface of the lungs and lines the inner surface of the rib cage Extensive, thin, moist, and slippery membrane Parietal and visceral Intrapleural space lies between the 2 pleural membranes and contains fluid Pneumothorax: presence of air in the intrapleural space on one side of the chest. Additional air increases pressure on the lung causing it to collapse. Respiration Exchange of gases between a living organism and its environment Breathing aka pulmonary ventilation is the process that moves air into and out of the lungs The exchange of gases between air in the lungs and in the blood is called external respiration Exchange of gases between the blood and the cells is called internal respiration Mechanics of Breathing 2 phases Inspiration- inhalation, moves air into lungs Expiration- exhalation, air moves out of lungs Air moves from an area where pressure is high to an area where pressure is lower. Respiratory muscles are responsible for the changes in the shape of the thoracic cavity that cause the air movements involved in breathing. Inspiration Occurs when chest cavity enlarges As cavity enlarges, the lungs expand and air rushes in Muscles of respiration are called inspiratory muscles and include the diaphragm and the external intercostals Expiration Inspiratory muscles relax Expiratory muscles are internal intercostals and abdominal muscles As the thoracic cavity decreases in size, the air pressure within it increases and air flows out of the lungs Exchange of Gases in Lungs Diffusion is movement down a concentration gradient Oxygen is continually removed from the blood and used by body cells Alveolar air is rich in oxygen: diffusion causes movement of oxygen from the area of high concentration (alveolar air) to the area of low concentration (capillary blood) Exchange of Gases in Lungs Blood flowing through the lung capillaries is high in carbon dioxide As cells remove oxygen, they add the waste product carbon dioxide to the blood Exchange of Gases in Tissues Internal respiration- exchange of gases that occurs between blood in tissue capillaries and the body cells Movement of oxygen and carbon dioxide during internal respiration is opposite from external respiration Diffusion is responsible for this movement Volumes of Air Exchanged in Pulmonary Ventilation Spirometer- a device that measures the amount of air exchanged in breathing. We breathe in about a pint of air with each breath. This amount is the tidal volume. Vital capacity is the largest amount of air that we can breathe out in one expiration. Volumes, cont’d Expiratory reserve volume is the amount of air that can be forcibly exhaled after expiring the tidal volume. Inspiratory reserve volume is the amount of air that can be forcibly inspired over and above a normal respiration. Residual volume is the air that remains in the lungs after the most forceful expiration. Regulation of Respiration The more work the body does, the more oxygen must be delivered to the cells. One way to do this is to increase the rate and depth of respirations. Heart beats faster, breathe faster, tidal volume increases during exercise. Regulation of Respiration Normal respiration depends on proper functioning of the muscles of respiration. They are stimulated by nervous impulses from the respiratory control centers located in the medulla and pons. These receptors sense the need for changing the rate or depth of respirations. Regulation of Respiration The 2 most important control centers are in the medulla Inspiratory center Expiratory center Pons has a modifying function Cerebral Cortex Influences respiration by modifying the rate at which neurons “fire” in the inspiratory and expiratory centers. We can voluntarily control our breathing, but there are limitations. Regardless of cerebral intent to the contrary, we resume breathing when our bodies sense the need for more oxygen. Receptors Influencing Respiration Chemoreceptors: Located in the carotid and aortic bodies Sensitive to increases in blood carbon dioxide levels and decreases in blood oxygen levels Receptors Influencing Respiration Pulmonary Stretch Receptors: Located throughout the pulmonary airways and in the alveoli Protect the resp system from excess stretching caused by harmful overinflation Types of Breathing Eupnea- normal respiratory rate Hyperventilation- very rapid and deep respirations Hypoventilation- very slow and shallow respirations Dyspnea- labored or difficult breathing Apnea- breathing stops completely for a short period Respiratory arrest- failure to resume breathing after a prolonged period of apnea