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Respiration Review Air bulk flow caused by lungs From air in lungs to red blood cells Blood bulk flow caused by heart From red blood cells to body cells Bulk Flow: Air into Lungs • Diaphragm allows inspiration • Intercostal muscles allow forceful expiration Diffusion of oxygen into Blood • The protein HEMOGLOBIN binds the oxygen tightly so that no diffusion occurs until the r.b.c. is near O2 deprived body cells Bulk Flow: Blood carries O2 to Body Cells The Major Components of Blood • Plasma: – Glucose, hormones, etc. suspended in a viscuous goo • White Blood Cells:(leukocytes) – Protect the cells from infection/invasion • Platelets: – Clot the blood to prevent it from spilling out when a rupture of the fluid conduit occurs • Red Blood Cells:(erythrocytes) – Transport O2 – 99% of all blood cells Red Blood Cells • The protein “Hemoglobin” binds to O2 • Binds CO2 more strongly than O2 • Binds CO much more strongly than CO2 (Carbon Monoxide Poisoning) • Contain no nucleus! • Recycled every week or so White Blood Cells • Slip in between blood vessel cells • Recognize and destroy foreign matter Platelets • Aid in blood clotting • Recognize micro tears in blood conduits and bind together to form a clot How blood is transported • Arteries: – Structures that carry blood away from the heart – Rigid to take pressure of blood right out of heart • Capillaries: – Very narrow and thin tubes between arteries and veins where diffusion occurs – Can close down or open up to regulate blood flow (e.g. stress, eating, etc...) • Veins: – Loosen to expand more (controlled by smooth muscles) – Store great quantities of blood Another Look at Blood Vessels How Blood Circulates: The Heart The Heart • Contraction of ventricals – Larger of heart chambers – Takes blood in from the atria – Pumps blood out to the body • Contraction of atria – Smaller chambers – Takes blood in from body – Pumps blood into the ventricals • Coordinated beating of atria then ventricals Cardiac Cycle • Right Ventrical pumps de-oxygenated blood to lungs • Left Ventrical pumps oxygenated blood to the body cells • Valves prevent backflow of blood Coordination of the Beating • Heart cells naturally beat slowly if ATP is present • If there was no coordination, the heart cells would all beat randomly (fibrillation) • Coordinated beating occurs because a group of cells (the pacemaker cells) send nerve impulses to the other cells stimulating them to beat at the right time • Atria beat from top down, pause, Ventricals beat from bottom up The Cardio-Pulmonary System